Parkinson's Disease Therapeutics: New Developments and Challenges Since the Introduction of Levodopa
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Title
Parkinson's Disease Therapeutics: New Developments and Challenges Since the Introduction of Levodopa
Authors
Keywords
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Journal
NEUROPSYCHOPHARMACOLOGY
Volume 37, Issue 1, Pages 213-246
Publisher
Springer Nature
Online
2011-09-28
DOI
10.1038/npp.2011.212
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Note: Only part of the references are listed.- Deep Brain Stimulation of Pedunculopontine Tegmental Nucleus (PPTg) Promotes Cognitive and Metabolic Changes: A Target-Specific Effect or Response to a Low-Frequency Pattern of Stimulation?
- (2012) A. Stefani et al. CLINICAL EEG AND NEUROSCIENCE
- Glutamate Receptors as Therapeutic Targets for Parkinsons Disease
- (2012) Kari Johnson et al. CNS & Neurological Disorders-Drug Targets
- Molecule of the Month
- (2012) Craig W. Lindsley CURRENT TOPICS IN MEDICINAL CHEMISTRY
- Association of Olfactory Bulb Volume and Olfactory Sulcus Depth with Olfactory Function in Patients with Parkinson Disease
- (2011) J. Wang et al. AMERICAN JOURNAL OF NEURORADIOLOGY
- Metabotropic glutamate receptor 5 antagonist protects dopaminergic and noradrenergic neurons from degeneration in MPTP-treated monkeys
- (2011) G. J. Masilamoni et al. BRAIN
- Discovery, Synthesis, and Structure−Activity Relationship Development of a Series ofN-(4-Acetamido)phenylpicolinamides as Positive Allosteric Modulators of Metabotropic Glutamate Receptor 4 (mGlu4) with CNS Exposure in Rats
- (2011) Darren W. Engers et al. JOURNAL OF MEDICINAL CHEMISTRY
- The Distinct Role of Medium Spiny Neurons and Cholinergic Interneurons in the D2/A2A Receptor Interaction in the Striatum: Implications for Parkinson's Disease
- (2011) A. Tozzi et al. JOURNAL OF NEUROSCIENCE
- Preladenant in patients with Parkinson's disease and motor fluctuations: a phase 2, double-blind, randomised trial
- (2011) Robert A Hauser et al. LANCET NEUROLOGY
- AAV2-GAD gene therapy for advanced Parkinson's disease: a double-blind, sham-surgery controlled, randomised trial
- (2011) Peter A LeWitt et al. LANCET NEUROLOGY
- Nonmotor Disturbances in Parkinson’s Disease
- (2011) Claudio L. Bassetti Neurodegenerative Diseases
- Methylphenidate for gait impairment in Parkinson disease: A randomized clinical trial
- (2011) A. J. Espay et al. NEUROLOGY
- The acute antiparkinsonian and antidyskinetic effect of AFQ056, a novel metabotropic glutamate receptor type 5 antagonist, in l-Dopa-treated parkinsonian monkeys
- (2011) Laurent Grégoire et al. PARKINSONISM & RELATED DISORDERS
- The metabotropic glutamate receptor antagonist 2-methyl-6-(phenylethynyl) pyridine decreases striatal VGlut2 expression in association with an attenuation of L-dopa-induced dyskinesias
- (2011) C. Marin et al. SYNAPSE
- Intraoperative Computed Tomography for Deep Brain Stimulation Surgery: Technique and Accuracy Assessment
- (2011) Kiarash Shahlaie et al. Operative Neurosurgery
- Clinical review of treatment options for select nonmotor symptoms of Parkinson's disease
- (2010) Lindy D. Wood et al. American Journal Geriatric Pharmacotherapy
- Depression in Parkinson's Disease: Symptom Improvement and Residual Symptoms After Acute Pharmacologic Management
- (2010) Roseanne DeFronzo Dobkin et al. AMERICAN JOURNAL OF GERIATRIC PSYCHIATRY
- Future of cell and gene therapies for Parkinson's disease
- (2010) Ole Isacson et al. ANNALS OF NEUROLOGY
- Premotor Parkinson's disease: Clinical features, detection, and prospects for treatment
- (2010) Andrew Siderowf et al. ANNALS OF NEUROLOGY
- Pathological gambling in Parkinson disease is reduced by amantadine
- (2010) Astrid Thomas et al. ANNALS OF NEUROLOGY
- Initiating levodopa/carbidopa therapy with and without entacapone in early Parkinson disease: The STRIDE-PD study
- (2010) Fabrizio Stocchi et al. ANNALS OF NEUROLOGY
- Metabotropic Glutamate Receptors: Physiology, Pharmacology, and Disease
- (2010) Colleen M. Niswender et al. Annual Review of Pharmacology and Toxicology
- Nonmotor Symptoms in Genetic Parkinson Disease
- (2010) Meike Kasten et al. ARCHIVES OF NEUROLOGY
- LRRK2 and Parkinson Disease
- (2010) Justus C. Dächsel et al. ARCHIVES OF NEUROLOGY
- Deep Brain Stimulation for Parkinson Disease
- (2010) Jeff M. Bronstein et al. ARCHIVES OF NEUROLOGY
- Effect of deep brain stimulation in the pedunculopontine nucleus on motor function in the rat 6-hydroxydopamine Parkinson model
- (2010) Felix Rauch et al. BEHAVIOURAL BRAIN RESEARCH
- Towards stem cell replacement therapies for Parkinson’s disease
- (2010) Ernest Arenas BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
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- (2010) Hyun-Jung Kim BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
- Olfaction as a biomarker in Parkinson’s disease
- (2010) James F Morley et al. Biomarkers in Medicine
- Optimized adeno-associated viral vector-mediated striatal DOPA delivery restores sensorimotor function and prevents dyskinesias in a model of advanced Parkinson’s disease
- (2010) Tomas Björklund et al. BRAIN
- Therapeutic potential of targeting group III metabotropic glutamate receptors in the treatment of Parkinson's disease
- (2010) Susan Duty BRITISH JOURNAL OF PHARMACOLOGY
- Gene Therapy in Parkinsonʼs Disease
- (2010) Li Rebekah Feng et al. CNS DRUGS
- Adenosine-Dopamine Interactions in the Pathophysiology and Treatment of CNS Disorders
- (2010) K. Fuxe et al. CNS Neuroscience & Therapeutics
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- (2010) T.M. Bridges et al. DRUG NEWS & PERSPECTIVES
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- (2010) W Michael Caudle et al. Expert Review of Neurotherapeutics
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- (2010) M. Politis et al. Science Translational Medicine
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- (2010) Liang Xu et al. Stem Cell Reviews and Reports
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- (2010) Liviu Aron et al. TRENDS IN NEUROSCIENCES
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- (2009) Michael S. Okun et al. ANNALS OF NEUROLOGY
- Scientific rationale for the development of gene therapy strategies for Parkinson's disease
- (2009) Tomas Björklund et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
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- (2009) Ya Zhou et al. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
- Effects of pedunculopontine nucleus area stimulation on gait disorders in Parkinson's disease
- (2009) M. U. Ferraye et al. BRAIN
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- (2009) Kjell Fuxe et al. CURRENT OPINION IN PHARMACOLOGY
- Discovery and Development of a Potent and Highly Selective Small Molecule Muscarinic Acetylcholine Receptor Subtype I (mAChR 1 or M1) Antagonist In Vitro and In Vivo Probe
- (2009) C. Weaver et al. CURRENT TOPICS IN MEDICINAL CHEMISTRY
- Perspectives on recent advances in the understanding and treatment of Parkinson’s disease
- (2009) A. H. Schapira et al. EUROPEAN JOURNAL OF NEUROLOGY
- Apomorphine and levodopa infusion therapies for advanced Parkinson’s disease: selection criteria and patient management
- (2009) Angelo Antonini et al. Expert Review of Neurotherapeutics
- Olfactory dysfunction as a diagnostic marker for Parkinson’s disease
- (2009) Antje Haehner et al. Expert Review of Neurotherapeutics
- Treatment of Parkinson’s disease by cortical stimulation
- (2009) Jean-Pascal Lefaucheur Expert Review of Neurotherapeutics
- Electrophysiological and behavioral evidence that modulation of metabotropic glutamate receptor 4 with a new agonist reverses experimental parkinsonism
- (2009) Corinne Beurrier et al. FASEB JOURNAL
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- (2009) Corey R Hopkins et al. Future Medicinal Chemistry
- Computer-assisted automatic localization of the human pedunculopontine nucleus in T1-weighted MR images: a preliminary study
- (2009) Yili Fu et al. International Journal of Medical Robotics and Computer Assisted Surgery
- Bilateral Deep Brain Stimulation vs Best Medical Therapy for Patients With Advanced Parkinson DiseaseA Randomized Controlled Trial
- (2009) Frances M. Weaver JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION
- Cortical and subcortical connections within the pedunculopontine nucleus of the primate Macaca mulatta determined using probabilistic diffusion tractography
- (2009) Bhooma R. Aravamuthan et al. JOURNAL OF CLINICAL NEUROSCIENCE
- Optimization of continuousin vivoDOPA production and studies on ectopic DA synthesis using rAAV5 vectors in Parkinsonian rats
- (2009) Tomas Björklund et al. JOURNAL OF NEUROCHEMISTRY
- Lack of functional relevance of isolated cell damage in transplants of Parkinson’s disease patients
- (2009) Oliver Cooper et al. JOURNAL OF NEUROLOGY
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- (2009) Laura B. Zahodne et al. JOURNAL OF NEUROLOGY
- Impact of STN-DBS on life and health satisfaction in patients with Parkinson's disease
- (2009) J. Ferrara et al. JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY
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- (2009) G Kagi et al. JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY
- Therapeutic efficacy of unilateral subthalamotomy in Parkinson's disease: results in 89 patients followed for up to 36 months
- (2009) L Alvarez et al. JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY
- Physiological identification of the human pedunculopontine nucleus
- (2009) S A Shimamoto et al. JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY
- Olfactory impairment is more marked in patients with mild dementia with Lewy bodies than those with mild Alzheimer disease
- (2009) S S Williams et al. JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY
- Predictors of cognitive and psychosocial outcome after STN DBS in Parkinson's Disease
- (2009) H. M. M. Smeding et al. JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY
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- Pharmacological Modulation of Glutamate Transmission in a Rat Model of L-DOPA-Induced Dyskinesia: Effects on Motor Behavior and Striatal Nuclear Signaling
- (2009) D. Rylander et al. JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS
- Non-motor functions in parkinsonian patients implanted in the pedunculopontine nucleus: Focus on sleep and cognitive domains
- (2009) Stefani Alessandro et al. JOURNAL OF THE NEUROLOGICAL SCIENCES
- Memantine in patients with Parkinson's disease dementia or dementia with Lewy bodies: a double-blind, placebo-controlled, multicentre trial
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- (2009) K Ray Chaudhuri et al. LANCET NEUROLOGY
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- (2009) Etienne C Hirsch et al. LANCET NEUROLOGY
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- (2008) J. L. Eberling et al. NEUROLOGY
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- (2008) A. Peppe et al. PARKINSONISM & RELATED DISORDERS
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- (2007) Christopher J. Langmead et al. PHARMACOLOGY & THERAPEUTICS
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