-Synuclein-Induced Down-Regulation of Nurr1 Disrupts GDNF Signaling in Nigral Dopamine Neurons

Anti-Parkinsonian Effects of Nurr1 Activator in Ubiquitin-Proteasome System Impairment Induced Animal Model of Parkinson’s Disease

(2012) Zhen Zhang et al.   CNS & Neurological Disorders-Drug Targets

Comparison of the behavioural and histological characteristics of the 6-OHDA and α-synuclein rat models of Parkinson's disease

(2012) M. Decressac et al.   EXPERIMENTAL NEUROLOGY

MicroRNA-124 Is a Subventricular Zone Neuronal Fate Determinant

(2012) M. Akerblom et al.   JOURNAL OF NEUROSCIENCE

Impaired neurotransmission caused by overexpression of  -synuclein in nigral dopamine neurons

(2012) M. Lundblad et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

GDNF fails to exert neuroprotection in a rat  -synuclein model of Parkinson's disease

(2011) M. Decressac et al.   BRAIN

The Sirtuin 2 microtubule deacetylase is an abundant neuronal protein that accumulates in the aging CNS

(2011) Michele M. Maxwell et al.   HUMAN MOLECULAR GENETICS

Signaling of Glial Cell Line-Derived Neurotrophic Factor and Its Receptor GFRα1 Induce Nurr1 and Pitx3 to Promote Survival of Grafted Midbrain-Derived Neural Stem Cells in a Rat Model of Parkinson Disease

(2011) Zhinian Lei et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

Pitx3 Is a Critical Mediator of GDNF-Induced BDNF Expression in Nigrostriatal Dopaminergic Neurons

(2011) C. Peng et al.   JOURNAL OF NEUROSCIENCE

 -Synuclein Negatively Regulates Protein Kinase C  Expression to Suppress Apoptosis in Dopaminergic Neurons by Reducing p300 Histone Acetyltransferase Activity

(2011) H. Jin et al.   JOURNAL OF NEUROSCIENCE

Increased efficacy of the 6-hydroxydopamine lesion of the median forebrain bundle in small rats, by modification of the stereotaxic coordinates

(2011) E.M. Torres et al.   JOURNAL OF NEUROSCIENCE METHODS

Parkinson's disease and α-synuclein expression

(2011) Michael J. Devine et al.   MOVEMENT DISORDERS

Priorities in Parkinson's disease research

(2011) Wassilios G. Meissner et al.   NATURE REVIEWS DRUG DISCOVERY

Progressive neurodegenerative and behavioural changes induced by AAV-mediated overexpression of α-synuclein in midbrain dopamine neurons

(2011) M. Decressac et al.   NEUROBIOLOGY OF DISEASE

Exogenous α-Synuclein Fibrils Induce Lewy Body Pathology Leading to Synaptic Dysfunction and Neuron Death

(2011) Laura A. Volpicelli-Daley et al.   NEURON

Loss of the miR-21 allele elevates the expression of its target genes and reduces tumorigenesis

(2011) X. Ma et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

MicroRNA-7 targets IGF1R (insulin-like growth factor 1 receptor) in tongue squamous cell carcinoma cells

(2010) Lu Jiang et al.   BIOCHEMICAL JOURNAL

Post-transcriptional Regulation of α-Synuclein Expression by mir-7 and mir-153

(2010) Epaminondas Doxakis   JOURNAL OF BIOLOGICAL CHEMISTRY

Bioactivity of AAV2-neurturin gene therapy (CERE-120): Differences between Parkinson's disease and nonhuman primate brains

(2010) Raymond T. Bartus et al.   MOVEMENT DISORDERS

α-synuclein aggregation reduces nigral myocyte enhancer Factor-2D in idiopathic and experimental Parkinson's disease

(2010) Yaping Chu et al.   NEUROBIOLOGY OF DISEASE

miR-22 Forms a Regulatory Loop in PTEN/AKT Pathway and Modulates Signaling Kinetics

(2010) Nadav Bar et al.   PLoS One

NR4A orphan nuclear receptors as mediators of CREB-dependent neuroprotection

(2010) N. Volakakis et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

α-Synuclein and dopamine at the crossroads of Parkinson's disease

(2010) Lara Lourenço Venda et al.   TRENDS IN NEUROSCIENCES

Repairing the parkinsonian brain with neurotrophic factors

(2010) Liviu Aron et al.   TRENDS IN NEUROSCIENCES

Pitx3 potentiates Nurr1 in dopamine neuron terminal differentiation through release of SMRT-mediated repression

(2009) F. M. J. Jacobs et al.   DEVELOPMENT

Dynamic Changes in Presynaptic and Axonal Transport Proteins Combined with Striatal Neuroinflammation Precede Dopaminergic Neuronal Loss in a Rat Model of AAV  -Synucleinopathy

(2009) C. Y. Chung et al.   JOURNAL OF NEUROSCIENCE

Nurr1 Is Required for Maintenance of Maturing and Adult Midbrain Dopamine Neurons

(2009) B. Kadkhodaei et al.   JOURNAL OF NEUROSCIENCE

Nuclear and neuritic distribution of serine-129 phosphorylated α-synuclein in transgenic mice

(2009) H. Schell et al.   NEUROSCIENCE

Characterisation of a novel NR4A2 mutation in Parkinson's disease brain

(2009) P.M.A. Sleiman et al.   NEUROSCIENCE LETTERS

Repression of  -synuclein expression and toxicity by microRNA-7

(2009) E. Junn et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Phosphorylation Does Not Prompt, Nor Prevent, the Formation of  -synuclein Toxic Species in a Rat Model of Parkinson's Disease

(2008) S. Azeredo da Silveira et al.   HUMAN MOLECULAR GENETICS

Absolute requirement of GDNF for adult catecholaminergic neuron survival

(2008) Alberto Pascual et al.   NATURE NEUROSCIENCE