Health benefits of walnut polyphenols: An exploration beyond their lipid profile

Urolithin A causes p21 up-regulation in prostate cancer cells

(2015) Claudia Sánchez-González et al.   EUROPEAN JOURNAL OF NUTRITION

Urolithins, gut microbiota-derived metabolites of ellagitannins, inhibit LPS-induced inflammation in RAW 264.7 murine macrophages

(2015) Jakub P. Piwowarski et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Ellagic acid enhances the antinociceptive action of venlafaxine in mouse acetic acid-induced pain: An isobolographic analysis

(2015) Mohammad Taghi Mansouri et al.   Pharmacological Reports

The ellagic acid-derived gut microbiota metabolite, urolithin A, potentiates the anticancer effects of 5-fluorouracil chemotherapy on human colon cancer cells

(2015) Antonio González-Sarrías et al.   Food & Function

Ellagic acid, an NF-κB inhibitor, ameliorates renal function in experimental diabetic nephropathy

(2014) Amjid Ahad et al.   CHEMICO-BIOLOGICAL INTERACTIONS

Metabolic Fate of Ellagitannins: Implications for Health, and Research Perspectives for Innovative Functional Foods

(2014) Cristina Garcia-Muñoz et al.   CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION

Ellagic acid protects against carrageenan-induced acute inflammation through inhibition of nuclear factor kappa B, inducible cyclooxygenase and proinflammatory cytokines and enhancement of interleukin-10 via an antioxidant mechanism

(2014) Nagla A. El-Shitany et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Ellagic Acid Metabolism by Human Gut Microbiota: Consistent Observation of Three Urolithin Phenotypes in Intervention Trials, Independent of Food Source, Age, and Health Status

(2014) Francisco A. Tomás-Barberán et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Role of Walnuts in Maintaining Brain Health with Age

(2014) Shibu M. Poulose et al.   JOURNAL OF NUTRITION

Walnuts Have Potential for Cancer Prevention and Treatment in Mice

(2014) W. Elaine Hardman   JOURNAL OF NUTRITION

Ellagic acid, a component of pomegranate fruit juice, suppresses androgen-dependent prostate carcinogenesis via induction of apoptosis

(2014) Aya Naiki-Ito et al.   PROSTATE

Walnut polyphenol metabolites, urolithins A and B, inhibit the expression of the prostate-specific antigen and the androgen receptor in prostate cancer cells

(2014) Claudia Sánchez-González et al.   Food & Function

Resveratrol and Alzheimer’s disease: message in a bottle on red wine and cognition

(2014) Alberto Granzotto et al.   Frontiers in Aging Neuroscience

Biology of Ageing and Role of Dietary Antioxidants

(2014) Cheng Peng et al.   Biomed Research International

A Walnut-Enriched Diet Reduces the Growth of LNCaP Human Prostate Cancer Xenografts in Nude Mice

(2013) Russel J. Reiter et al.   CANCER INVESTIGATION

MicroRNA ‘signature’ during estrogen-mediated mammary carcinogenesis and its reversal by ellagic acid intervention

(2013) Radha Munagala et al.   CANCER LETTERS

Central and peripheral antinociceptive effects of ellagic acid in different animal models of pain

(2013) Mohammad Taghi Mansouri et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Biological Significance of Urolithins, the Gut Microbial Ellagic Acid-Derived Metabolites: The Evidence So Far

(2013) Juan Carlos Espín et al.   Evidence-based Complementary and Alternative Medicine

Pomegranate Juice Metabolites, Ellagic Acid and Urolithin A, Synergistically Inhibit Androgen-Independent Prostate Cancer Cell Growth via Distinct Effects on Cell Cycle Control and Apoptosis

(2013) Roberto Vicinanza et al.   Evidence-based Complementary and Alternative Medicine

In vitro antioxidant and antiproliferative effects of ellagic acid and its colonic metabolite, urolithins, on human bladder cancer T24 cells

(2013) Zhenpeng Qiu et al.   FOOD AND CHEMICAL TOXICOLOGY

Comprehensive identification of walnut polyphenols by liquid chromatography coupled to linear ion trap–Orbitrap mass spectrometry

(2013) Jorge Regueiro et al.   FOOD CHEMISTRY

Effects of Walnuts on Endothelial Function in Overweight Adults with Visceral Obesity: A Randomized, Controlled, Crossover Trial

(2013) David L Katz et al.   JOURNAL OF THE AMERICAN COLLEGE OF NUTRITION

Primary Prevention of Cardiovascular Disease with a Mediterranean Diet

(2013) Ramón Estruch et al.   NEW ENGLAND JOURNAL OF MEDICINE

Atheroprotective effect of dietary walnut intake in ApoE-deficient mice: Involvement of lipids and coagulation factors

(2013) Reyhan Nergiz-Ünal et al.   THROMBOSIS RESEARCH

Modulation of signaling pathways in prostate cancer by green tea polyphenols

(2012) Naghma Khan et al.   BIOCHEMICAL PHARMACOLOGY

A high-fat diet containing whole walnuts (Juglans regia) reduces tumour size and growth along with plasma insulin-like growth factor 1 in the transgenic adenocarcinoma of the mouse prostate model

(2012) Paul A. Davis et al.   BRITISH JOURNAL OF NUTRITION

Validation of the Antiproliferative Effects of Organic Extracts from the Green Husk ofJuglans regiaL. on PC-3 Human Prostate Cancer Cells by Assessment of Apoptosis-Related Genes

(2012) Ali A. Alshatwi et al.   Evidence-based Complementary and Alternative Medicine

Ellagic acid protects human keratinocyte (HaCaT) cells against UVA-induced oxidative stress and apoptosis through the upregulation of the HO-1 and Nrf-2 antioxidant genes

(2012) You-Cheng Hseu et al.   FOOD AND CHEMICAL TOXICOLOGY

Intestinal Ellagitannin Metabolites Ameliorate Cytokine-Induced Inflammation and Associated Molecular Markers in Human Colon Fibroblasts

(2012) Juan A. Giménez-Bastida et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

In vivo anti-inflammatory and antioxidant properties of ellagitannin metabolite urolithin A

(2011) Hidekazu Ishimoto et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Can phytochemical antioxidant rich foods act as anti-cancer agents?

(2011) Sunan Wang et al.   FOOD RESEARCH INTERNATIONAL

Ellagitannins, ellagic acid and their derived metabolites: A review about source, metabolism, functions and health

(2011) J.M. Landete   FOOD RESEARCH INTERNATIONAL

Ellagic acid protects mitochondria from β-adrenergic agonist induced myocardial damage in rats; evidence from in vivo, in vitro and ultra structural study

(2011) Maharajan Mari Kannan et al.   FOOD RESEARCH INTERNATIONAL

Anti-carcinogenic action of ellagic acid mediated via modulation of oxidative stress regulated genes in Dalton lymphoma bearing mice

(2011) Sudha Mishra et al.   LEUKEMIA & LYMPHOMA

Protective Effects of Walnut Extract Against Amyloid Beta Peptide-Induced Cell Death and Oxidative Stress in PC12 Cells

(2011) Balu Muthaiyah et al.   NEUROCHEMICAL RESEARCH

Dietary walnuts inhibit colorectal cancer growth in mice by suppressing angiogenesis

(2011) Jutta M. Nagel et al.   NUTRITION

Dietary Walnut Suppressed Mammary Gland Tumorigenesis in the C(3)1 TAg Mouse

(2011) W. Elaine Hardman et al.   NUTRITION AND CANCER-AN INTERNATIONAL JOURNAL

Polyphenols as small molecular inhibitors of signaling cascades in carcinogenesis

(2011) Nam Joo Kang et al.   PHARMACOLOGY & THERAPEUTICS

Nuts, especially walnuts, have both antioxidant quantity and efficacy and exhibit significant potential health benefits

(2011) Joe A. Vinson et al.   Food & Function

Coffee polyphenols suppress diet-induced body fat accumulation by downregulating SREBP-1c and related molecules in C57BL/6J mice

(2010) Takatoshi Murase et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Differential Inhibitory Effects of the Polyphenol Ellagic Acid on Inflammatory Mediators NF-κB, iNOS, COX-2, TNF-α, and IL-6 in 1,2-Dimethylhydrazine-Induced Rat Colon Carcinogenesis

(2010) Syed Umesalma et al.   BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY

NF-κB-dependent anti-inflammatory activity of urolithins, gut microbiota ellagic acid-derived metabolites, in human colonic fibroblasts

(2010) Antonio González-Sarrías et al.   BRITISH JOURNAL OF NUTRITION

Pomegranate Ellagitannin-Derived Compounds Exhibit Antiproliferative and Antiaromatase Activity in Breast Cancer Cells In vitro

(2010) L. S. Adams et al.   Cancer Prevention Research

Angiogenesis as a potential target of pharmaconutrients in cancer therapy

(2010) Virginie Granci et al.   CURRENT OPINION IN CLINICAL NUTRITION AND METABOLIC CARE

Signaling by ROS drives inflammasome activation

(2010) Fabio Martinon   EUROPEAN JOURNAL OF IMMUNOLOGY

In vivo nutrigenomic effects of virgin olive oil polyphenols within the frame of the Mediterranean diet: a randomized controlled trial

(2010) Valentini Konstantinidou et al.   FASEB JOURNAL

Inflammatory Mediators of Hepatic Steatosis

(2010) Elizabeth Hijona et al.   MEDIATORS OF INFLAMMATION

Role of Reactive Oxygen Species in the Progression of Type 2 Diabetes and Atherosclerosis

(2010) Hideaki Kaneto et al.   MEDIATORS OF INFLAMMATION

Almond consumption improved glycemic control and lipid profiles in patients with type 2 diabetes mellitus

(2010) Sing-Chung Li et al.   METABOLISM-CLINICAL AND EXPERIMENTAL

Ellagitannins, ellagic acid and vascular health

(2010) Mar Larrosa et al.   MOLECULAR ASPECTS OF MEDICINE

Tea polyphenol (−)-epigallocatechin-3-gallate inhibits nicotine- and estrogen-induced α9-nicotinic acetylcholine receptor upregulation in human breast cancer cells

(2010) Shih-Hsin Tu et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Inflammation, Cytokines, Immune Response, Apolipoprotein E, Cholesterol, and Oxidative Stress in Alzheimer Disease: Therapeutic Implications

(2010) Giuseppina Candore et al.   REJUVENATION RESEARCH

Ellagic acid promotes Aβ42 fibrillization and inhibits Aβ42-induced neurotoxicity

(2009) Ying Feng et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Effect of ellagic acid on the expression of human telomerase reverse transcriptase (hTERT) α+β+ transcript in estrogen receptor-positive MCF-7 breast cancer cells

(2009) Areti Strati et al.   CLINICAL BIOCHEMISTRY

Inflammation and the pathogenesis of age-related macular degeneration

(2009) Albert J Augustin et al.   EXPERT OPINION ON THERAPEUTIC TARGETS

Human cancer cell antiproliferative and antioxidant activities of Juglans regia L.

(2009) Márcia Carvalho et al.   FOOD AND CHEMICAL TOXICOLOGY

Oxidative risk for atherothrombotic cardiovascular disease

(2009) Jane A. Leopold et al.   FREE RADICAL BIOLOGY AND MEDICINE

Effects of Pomegranate Chemical Constituents/Intestinal Microbial Metabolites on CYP1B1 in 22Rv1 Prostate Cancer Cells

(2009) Sashi G. Kasimsetty et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Effects of Fruit Ellagitannin Extracts, Ellagic Acid, and Their Colonic Metabolite, Urolithin A, on Wnt Signaling†

(2009) Meenakshi Sharma et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Gene expression, cell cycle arrest and MAPK signalling regulation in Caco-2 cells exposed to ellagic acid and its metabolites, urolithins

(2009) Antonio González-Sarrías et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Occurrence of urolithins, gut microbiota ellagic acid metabolites and proliferation markers expression response in the human prostate gland upon consumption of walnuts and pomegranate juice

(2009) Antonio González-Sarrías et al.   MOLECULAR NUTRITION & FOOD RESEARCH

A novel component of the metabolic syndrome: The oxidative stress

(2009) E. Hopps et al.   NUTRITION METABOLISM AND CARDIOVASCULAR DISEASES

Effects of one serving of mixed nuts on serum lipids, insulin resistance and inflammatory markers in patients with the metabolic syndrome

(2009) P. Casas-Agustench et al.   NUTRITION METABOLISM AND CARDIOVASCULAR DISEASES

Effect of ellagic acid on proliferation, cell adhesion and apoptosis in SH-SY5Y human neuroblastoma cells

(2008) Christina Fjaeraa et al.   BIOMEDICINE & PHARMACOTHERAPY

Coffee consumption and the risk of cancer: An overview

(2008) André Nkondjock   CANCER LETTERS

The effect of walnut intake on factors related to prostate and vascular health in older men

(2008) Kim J Spaccarotella et al.   Nutrition Journal