PNPLA3/adiponutrin functions in lipid droplet formation

PNPLA3 is regulated by glucose in human hepatocytes, and its I148M mutant slows down triglyceride hydrolysis

(2012) Julia Perttilä et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Mouse patatin-like phospholipase domain-containing 3 influences systemic lipid and glucose homeostasis

(2011) Aijun Qiao et al.   HEPATOLOGY

Expression and Characterization of a PNPLA3 Protein Isoform (I148M) Associated with Nonalcoholic Fatty Liver Disease

(2011) Yongcheng Huang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Human Fatty Liver Disease: Old Questions and New Insights

(2011) J. C. Cohen et al.   SCIENCE

Regulation of the promoter region of the human adiponutrin/PNPLA3 gene by glucose and insulin

(2010) Sharleen M. Rae-Whitcombe et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Patatin-like phospholipase domain-containing 3/adiponutrin deficiency in mice is not associated with fatty liver disease

(2010) Weiqin Chen et al.   HEPATOLOGY

Distinct regulation of adiponutrin/PNPLA3 gene expression by the transcription factors ChREBP and SREBP1c in mouse and human hepatocytes

(2010) Céline Dubuquoy et al.   JOURNAL OF HEPATOLOGY

Pnpla3/Adiponutrin deficiency in mice does not contribute to fatty liver disease or metabolic syndrome

(2010) Mahesh K. Basantani et al.   JOURNAL OF LIPID RESEARCH

A feed-forward loop amplifies nutritional regulation of PNPLA3

(2010) Yongcheng Huang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A Sequence Variation (I148M) in PNPLA3 Associated with Nonalcoholic Fatty Liver Disease Disrupts Triglyceride Hydrolysis

(2009) Shaoqing He et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Adipose Triglyceride Lipase Deficiency Causes Tissue-specific Changes in Insulin Signaling

(2009) Petra C. Kienesberger et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The expression level of non-alcoholic fatty liver disease-related gene PNPLA3 in hepatocytes is highly influenced by hepatic lipid status

(2009) Menno Hoekstra et al.   JOURNAL OF HEPATOLOGY

Characterization of desnutrin functional domains: critical residues for triacylglycerol hydrolysis in cultured cells

(2009) Robin E. Duncan et al.   JOURNAL OF LIPID RESEARCH

Adoption of PERILIPIN as a unifying nomenclature for the mammalian PAT-family of intracellular lipid storage droplet proteins: TABLE 1.

(2009) Alan R. Kimmel et al.   JOURNAL OF LIPID RESEARCH

The C-terminal Region of Human Adipose Triglyceride Lipase Affects Enzyme Activity and Lipid Droplet Binding

(2008) Martina Schweiger et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Lysobisphosphatidic Acid Controls Endosomal Cholesterol Levels

(2008) Julien Chevallier et al.   JOURNAL OF BIOLOGICAL CHEMISTRY