Pnpla3/Adiponutrin deficiency in mice does not contribute to fatty liver disease or metabolic syndrome

Patatin-like phospholipase domain-containing 3/adiponutrin deficiency in mice is not associated with fatty liver disease

(2010) Weiqin Chen et al.   HEPATOLOGY

I148M patatin-like phospholipase domain-containing 3 gene variant and severity of pediatric nonalcoholic fatty liver disease

(2010) Luca Valenti et al.   HEPATOLOGY

PNPLA3variants specifically confer increased risk for histologic nonalcoholic fatty liver disease but not metabolic disease

(2010) Elizabeth K. Speliotes et al.   HEPATOLOGY

The association of genetic variability in patatin-like phospholipase domain-containing protein 3 (PNPLA3) with histological severity of nonalcoholic fatty liver disease

(2010) Yaron Rotman et al.   HEPATOLOGY

Homozygosity for the patatin-like phospholipase-3/adiponutrin I148M polymorphism influences liver fibrosis in patients with nonalcoholic fatty liver disease

(2010) Luca Valenti et al.   HEPATOLOGY

The 148M allele of the PNPLA3 gene is associated with indices of liver damage early in life

(2010) Stefano Romeo et al.   JOURNAL OF HEPATOLOGY

The role of fructose in the pathogenesis of NAFLD and the metabolic syndrome

(2010) Jung Sub Lim et al.   Nature Reviews Gastroenterology & Hepatology

A feed-forward loop amplifies nutritional regulation of PNPLA3

(2010) Yongcheng Huang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Automated Lipid Identification and Quantification by Multidimensional Mass Spectrometry-Based Shotgun Lipidomics

(2009) Kui Yang et al.   ANALYTICAL CHEMISTRY

The MIQE Guidelines: Minimum Information for Publication of Quantitative Real-Time PCR Experiments

(2009) S. A. Bustin et al.   CLINICAL CHEMISTRY

Dissociation Between Fatty Liver and Insulin Resistance in Humans Carrying a Variant of the Patatin-Like Phospholipase 3 Gene

(2009) K. Kantartzis et al.   DIABETES

A single nucleotide polymorphism (SNP) rs2072907 in the adiponutrin gene (ADPN) was not associated with obesity and type 2 diabetes in Chinese Population

(2009) Hua Liang et al.   DIABETES RESEARCH AND CLINICAL PRACTICE

A common variant in PNPLA3, which encodes adiponutrin, is associated with liver fat content in humans

(2009) A. Kotronen et al.   DIABETOLOGIA

Genetic evidence for a role of adiponutrin in the metabolism of apolipoprotein B-containing lipoproteins

(2009) B. Kollerits et al.   HUMAN MOLECULAR GENETICS

Morbid obesity exposes the association between PNPLA3 I148M (rs738409) and indices of hepatic injury in individuals of European descent

(2009) S Romeo et al.   INTERNATIONAL JOURNAL OF OBESITY

A Sequence Variation (I148M) in PNPLA3 Associated with Nonalcoholic Fatty Liver Disease Disrupts Triglyceride Hydrolysis

(2009) Shaoqing He et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Adipose Triglyceride Lipase Deficiency Causes Tissue-specific Changes in Insulin Signaling

(2009) Petra C. Kienesberger et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The expression level of non-alcoholic fatty liver disease-related gene PNPLA3 in hepatocytes is highly influenced by hepatic lipid status

(2009) Menno Hoekstra et al.   JOURNAL OF HEPATOLOGY

A nonsynonymous gene variant in the adiponutrin gene is associated with nonalcoholic fatty liver disease severity

(2009) Silvia Sookoian et al.   JOURNAL OF LIPID RESEARCH

A common variant in the adiponutrin gene influences liver enzyme values

(2009) B. Kollerits et al.   JOURNAL OF MEDICAL GENETICS

Tri-iodothyronine upregulates adiponutrin mRNA expression in rat and human adipocytes

(2009) R.M. Calvo et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Genetic Variance in the Adiponutrin Gene Family and Childhood Obesity

(2009) Lovisa E. Johansson et al.   PLoS One

Population-Based Genome-wide Association Studies Reveal Six Loci Influencing Plasma Levels of Liver Enzymes

(2008) Xin Yuan et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Causes and Metabolic Consequences of Fatty Liver

(2008) Norbert Stefan et al.   ENDOCRINE REVIEWS

The Metabolic Syndrome

(2008) Marc-Andre Cornier et al.   ENDOCRINE REVIEWS

Polymorphisms in the adiponutrin gene are associated with increased insulin secretion and obesity

(2008) Lovisa E Johansson et al.   EUROPEAN JOURNAL OF ENDOCRINOLOGY

Mammalian patatin domain containing proteins: a family with diverse lipolytic activities involved in multiple biological functions

(2008) Petra C. Kienesberger et al.   JOURNAL OF LIPID RESEARCH

Genetic variation in PNPLA3 confers susceptibility to nonalcoholic fatty liver disease

(2008) Stefano Romeo et al.   NATURE GENETICS

Fatty Liver

(2007) Anna Kotronen et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY