A comparison of methods for inferring causal relationships between genotype and phenotype using additional biological measurements

Genome-wide association analysis identifies novel blood pressure loci and offers biological insights into cardiovascular risk

(2017) Helen R Warren et al.   NATURE GENETICS

Genome-wide association analyses for lung function and chronic obstructive pulmonary disease identify new loci and potential druggable targets

(2017) Louise V Wain et al.   NATURE GENETICS

Consistent Estimation in Mendelian Randomization with Some Invalid Instruments Using a Weighted Median Estimator

(2016) Jack Bowden et al.   GENETIC EPIDEMIOLOGY

Challenges and novel approaches for investigating molecular mediation

(2016) R.C. Richmond et al.   HUMAN MOLECULAR GENETICS

Identification, analysis, and interpretation of a human serum metabolomics causal network in an observational study

(2016) Azam Yazdani et al.   JOURNAL OF BIOMEDICAL INFORMATICS

Generating a robust statistical causal structure over 13 cardiovascular disease risk factors using genomics data

(2016) Azam Yazdani et al.   JOURNAL OF BIOMEDICAL INFORMATICS

Integration of summary data from GWAS and eQTL studies predicts complex trait gene targets

(2016) Zhihong Zhu et al.   NATURE GENETICS

A Causal Network Analysis of the Fatty Acid Metabolome in African-Americans Reveals a Critical Role for Palmitoleate and Margarate

(2016) Azam Yazdani et al.   OMICS-A JOURNAL OF INTEGRATIVE BIOLOGY

Predicting gene targets from integrative analyses of summary data from GWAS and eQTL studies for 28 human complex traits

(2016) Jennifer M. Whitehead Pavlides et al.   Genome Medicine

Mendelian Randomization versus Path Models: Making Causal Inferences in Genetic Epidemiology

(2015) Andreas Ziegler et al.   HUMAN HEREDITY

International genome-wide meta-analysis identifies new primary biliary cirrhosis risk loci and targetable pathogenic pathways

(2015) Heather J. Cordell et al.   Nature Communications

Learning Bayesian Networks with thebnlearnRPackage

(2015) Marco Scutari   Journal of Statistical Software

Integrative genomic analysis identifies epigenetic marks that mediate genetic risk for epithelial ovarian cancer

(2014) Devin C Koestler et al.   BMC Medical Genomics

Mendelian randomization: genetic anchors for causal inference in epidemiological studies

(2014) G. Davey Smith et al.   HUMAN MOLECULAR GENETICS

Network Mendelian randomization: using genetic variants as instrumental variables to investigate mediation in causal pathways

(2014) S. Burgess et al.   INTERNATIONAL JOURNAL OF EPIDEMIOLOGY

Interrogating causal pathways linking genetic variants, small molecule metabolites, and circulating lipids

(2014) So-Youn Shin et al.   Genome Medicine

Epigenome-wide association data implicate DNA methylation as an intermediary of genetic risk in rheumatoid arthritis

(2013) Yun Liu et al.   NATURE BIOTECHNOLOGY

A Unified Framework for Association Analysis with Multiple Related Phenotypes

(2013) Matthew Stephens   PLoS One

Five Years of GWAS Discovery

(2012) Peter M. Visscher et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Stitching together Multiple Data Dimensions Reveals Interacting Metabolomic and Transcriptomic Networks That Modulate Cell Regulation

(2012) Jun Zhu et al.   PLOS BIOLOGY

Disentangling molecular relationships with a causal inference test

(2009) Joshua Millstein et al.   BMC GENETICS