An overview of structure–activity relationship studies of curcumin analogs as antioxidant and anti-inflammatory agents

Pharmacological protection of mitochondrial function mitigates acute limb ischemia/reperfusion injury

(2016) Wei Bi et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Synthesis of unsymmetrical monocarbonyl curcumin analogues with potent inhibition on prostaglandin E 2 production in LPS-induced murine and human macrophages cell lines

(2016) Mohd Fadhlizil Fasihi Mohd Aluwi et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Evaluation of multifunctional synthetic tetralone derivatives for treatment of Alzheimer's disease

(2016) Jing Leng et al.   Chemical Biology & Drug Design

Design, structure activity relationship, cytotoxicity and evaluation of antioxidant activity of curcumin derivatives/analogues

(2016) Pramod K. Sahu   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Synthesis and optimization of novel allylated mono-carbonyl analogs of curcumin (MACs) act as potent anti-inflammatory agents against LPS-induced acute lung injury (ALI) in rats

(2016) Heping Zhu et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Synthesis of α,β-Unsaturated Carbonyl-Based Compounds, Oxime and Oxime Ether Analogs as Potential Anticancer Agents for Overcoming Cancer Multidrug Resistance by Modulation of Efflux Pumps in Tumor Cells

(2016) Hua-Li Qin et al.   JOURNAL OF MEDICINAL CHEMISTRY

Radio-protective effect of some new curcumin analogues

(2016) Marwa G. El-Gazzar et al.   JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY B-BIOLOGY

Nitric oxide inhibitory activity and antioxidant evaluations of 2-benzoyl-6-benzylidenecyclohexanone analogs, a novel series of curcuminoid and diarylpentanoid derivatives

(2015) Sze Wei Leong et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Synthesis and Anti-Inflammatory Evaluation of Novel C66 Analogs for the Treatment of LPS-Induced Acute Lung Injury

(2015) Jianpeng Feng et al.   Chemical Biology & Drug Design

Antioxidant activity and electrochemical elucidation of the enigmatic redox behavior of curcumin and its structurally modified analogues

(2015) Niki S. Jha et al.   ELECTROCHIMICA ACTA

Immunomodulatory effects of diarylpentanoid analogues of curcumin

(2015) Syed Nasir Abbas Bukhari et al.   MEDICINAL CHEMISTRY RESEARCH

Synthesis, biological evaluation and QSAR studies of diarylpentanoid analogues as potential nitric oxideinhibitors

(2015) S. M. Mohd Faudzi et al.   MedChemComm

Synthesis and biological evaluation of a novel class of curcumin analogs as anti-inflammatory agents for prevention and treatment of sepsis in mouse model

(2015) Chenguang Zhao et al.   Drug Design Development and Therapy

Pharmacological evaluation and docking studies of α,β-unsaturated carbonyl based synthetic compounds as inhibitors of secretory phospholipase A2, cyclooxygenases, lipoxygenase and proinflammatory cytokines

(2014) Syed Nasir Abbas Bukhari et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Effects of Novel Diarylpentanoid Analogues of Curcumin on Secretory Phospholipase A2, Cyclooxygenases, Lipo-oxygenase, and Microsomal Prostaglandin E Synthase-1

(2014) Waqas Ahmad et al.   Chemical Biology & Drug Design

Synthesis of α, β-unsaturated carbonyl based compounds as acetylcholinesterase and butyrylcholinesterase inhibitors: Characterization, molecular modeling, QSAR studies and effect against amyloid β-induced cytotoxicity

(2014) Syed Nasir Abbas Bukhari et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Biological Activity and Molecular Docking Studies of Curcumin-Related α,β-Unsaturated Carbonyl-Based Synthetic Compounds as Anticancer Agents and Mushroom Tyrosinase Inhibitors

(2014) Syed Nasir Abbas Bukhari et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Synthesis and Sar Study of Diarylpentanoid Analogues as New Anti-Inflammatory Agents

(2014) Sze Leong et al.   MOLECULES

Anti-proliferative, anti-inflammatory and antioxidant effects of curcumin analogue A2

(2013) Zhi-Yun Du et al.   ARCHIVES OF PHARMACAL RESEARCH

Mechanisms of Resolution of Inflammation

(2011) Benjamin H. Maskrey et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Curcumin analogues as possible anti-proliferative & anti-inflammatory agents

(2011) A.-M. Katsori et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Effects of diarylpentanoid analogues of curcumin on chemiluminescence and chemotactic activities of phagocytes

(2011) Ibrahim Jantan et al.   JOURNAL OF PHARMACY AND PHARMACOLOGY

Synthesis and biological evaluation of novel curcumin analogues as anti-inflammatory, anti-cancer and anti-oxidant agents

(2011) Babasaheb P. Bandgar et al.   MEDICINAL CHEMISTRY RESEARCH

Synthesis of mono-carbonyl analogues of curcumin and their effects on inhibition of cytokine release in LPS-stimulated RAW 264.7 macrophages

(2010) Chengguang Zhao et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Exploration and synthesis of curcumin analogues with improved structural stability both in vitro and in vivo as cytotoxic agents

(2009) Guang Liang et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Synthesis and biological evaluation of curcumin-like diarylpentanoid analogues for anti-inflammatory, antioxidant and anti-tyrosinase activities

(2009) Ka-Heng Lee et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

A synthetic curcuminoid derivative inhibits nitric oxide and proinflammatory cytokine synthesis

(2009) Chau Ling Tham et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Antioxidant capacity of curcumin-directed analogues: Structure–activity relationship and influence of microenvironment

(2009) Ya-Jing Shang et al.   FOOD CHEMISTRY

Inhibition of LPS-induced production of inflammatory factors in the macrophages by mono-carbonyl analogues of curcumin

(2009) Guang Liang et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Biological activities of curcumin and its analogues (Congeners) made by man and Mother Nature

(2008) Preetha Anand et al.   BIOCHEMICAL PHARMACOLOGY

Synthesis and evaluation of electron-rich curcumin analogues

(2008) Michael W. Amolins et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Synthesis and anti-inflammatory activities of mono-carbonyl analogues of curcumin

(2008) Guang Liang et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Synthesis, crystal structure and anti-inflammatory properties of curcumin analogues

(2008) Guang Liang et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Dimethoxycurcumin, a synthetic curcumin analogue with higher metabolic stability, inhibits NO production, inducible NO synthase expression and NF-κB activation in RAW264.7 macrophages activated with LPS

(2008) Hyun-Ock Pae et al.   MOLECULAR NUTRITION & FOOD RESEARCH