Therapeutic Role of Functional Components in Alliums for Preventive Chronic Disease in Human Being

Role of p38 MAPK activation and mitochondrial cytochrome-c release in allicin-induced apoptosis in SK-N-SH cells

(2016) Jianhui Zhuang et al.   ANTI-CANCER DRUGS

Attenuation of oxidative stress, inflammation, and endothelial dysfunction in hypercholesterolemic rabbits by allicin

(2016) Ahmed R. El-Sheakh et al.   CANADIAN JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY

Diallyl Disulfide (DADS), a Constituent of Garlic, Inactivates NF- B and Prevents Colitis-Induced Colorectal Cancer by Inhibiting GSK-3 

(2016) S. M. Saud et al.   Cancer Prevention Research

The flavonoid fisetin as an anticancer agent targeting the growth signaling pathways

(2016) Thamaraiselvan Rengarajan et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Garlic Attenuates Plasma and Kidney ACE-1 and AngII Modulations in Early Streptozotocin-Induced Diabetic Rats: Renal Clearance and Blood Pressure Implications

(2016) Khaled K. Al-Qattan et al.   Evidence-based Complementary and Alternative Medicine

Inhibition ofα-Glucosidase by Thiosulfinate as a Target for Glucose Modulation in Diabetic Rats

(2016) Abdulrahman L. Al-Malki   Evidence-based Complementary and Alternative Medicine

A novel reductive amination method with isotopic formaldehydes for the preparation of internal standard and standards for determining organosulfur compounds in garlic

(2016) De-Cheng Tsai et al.   FOOD CHEMISTRY

Identification of QTLs for resistant starch and total alkaloid content in brown and polished rice

(2016) Y.W. Zeng et al.   GENETICS AND MOLECULAR RESEARCH

Consumption of Fresh Yellow Onion Ameliorates Hyperglycemia and Insulin Resistance in Breast Cancer Patients During Doxorubicin-Based Chemotherapy: A Randomized Controlled Clinical Trial

(2016) Farnaz Jafarpour-Sadegh et al.   INTEGRATIVE CANCER THERAPIES

Diet Supplementation with Allicin Protects against Alcoholic Fatty Liver Disease in Mice by Improving Anti-inflammation and Antioxidative Functions

(2016) Suraphan Panyod et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Aged Garlic Extract Attenuates Neuronal Injury in a Rat Model of Spinal Cord Ischemia/Reperfusion Injury

(2016) Berker Cemil et al.   JOURNAL OF MEDICINAL FOOD

Garlic-Derived Organic Polysulfides and Myocardial Protection

(2016) Jessica M Bradley et al.   JOURNAL OF NUTRITION

Garlic and Heart Disease

(2016) Ravi Varshney et al.   JOURNAL OF NUTRITION

A new phenylpropanoid glucoside and a chain compound from the roots of Allium tuberosum

(2016) Yun-Shan Fang et al.   NATURAL PRODUCT RESEARCH

Effect of garlic on plasma lipoprotein(a) concentrations: A systematic review and meta-analysis of randomized controlled clinical trials

(2016) Amirhossein Sahebkar et al.   NUTRITION

Allium cepaExtract and Quercetin Protect Neuronal Cells from Oxidative Stress via PKC-εInactivation/ERK1/2 Activation

(2016) Bo Kyung Lee et al.   Oxidative Medicine and Cellular Longevity

Interaction of Hydrogen Sulfide with Nitric Oxide in the Cardiovascular System

(2016) B. V. Nagpure et al.   Oxidative Medicine and Cellular Longevity

Vasorelaxant Effect of a New Hydrogen Sulfide-Nitric Oxide Conjugated Donor in Isolated Rat Aortic Rings through cGMP Pathway

(2016) Dan Wu et al.   Oxidative Medicine and Cellular Longevity

Mechanisms of Neuroprotection by Quercetin: Counteracting Oxidative Stress and More

(2016) Lucio G. Costa et al.   Oxidative Medicine and Cellular Longevity

Anti-Proliferation Effects of Garlic (Allium sativumL.) on the Progression of Benign Prostatic Hyperplasia

(2016) Kyung-Sook Chung et al.   PHYTOTHERAPY RESEARCH

Purification and characterization of a soluble glycoprotein from garlic (Allium sativum) and itsin vitrobioactivity

(2016) Yan Wang et al.   PREPARATIVE BIOCHEMISTRY & BIOTECHNOLOGY

Onionin A inhibits ovarian cancer progression by suppressing cancer cell proliferation and the protumour function of macrophages

(2016) Junko Tsuboki et al.   Scientific Reports

In situ allicin generation using targeted alliinase delivery for inhibition of MIA PaCa-2 cells via epigenetic changes, oxidative stress and cyclin-dependent kinase inhibitor (CDKI) expression

(2015) Sagar V. Chhabria et al.   APOPTOSIS

Two new phenylpropane glycosides from Allium tuberosum Rottler

(2015) Sang Hyun Han et al.   ARCHIVES OF PHARMACAL RESEARCH

Coevolution between Human's Anticancer Activities and Functional Foods from Crop Origin Center in the World

(2015) Ya-Wen Zeng et al.   Asian Pacific Journal of Cancer Prevention

A novel natural compound from garlic (Allium sativum L.) with therapeutic effects against experimental polymicrobial sepsis

(2015) Sung Kyun Lee et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

The defense substance allicin from garlic permeabilizes membranes of Beta vulgaris, Rhoeo discolor, Chara corallina and artificial lipid bilayers

(2015) Martin C.H. Gruhlke et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

H2S-induced S-sulfhydration of pyruvate carboxylase contributes to gluconeogenesis in liver cells

(2015) YoungJun Ju et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Emerging critical roles of Fe–S clusters in DNA replication and repair

(2015) Jill O. Fuss et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Effects of a quercetin-rich onion skin extract on 24 h ambulatory blood pressure and endothelial function in overweight-to-obese patients with (pre-)hypertension: a randomised double-blinded placebo-controlled cross-over trial

(2015) Verena Brüll et al.   BRITISH JOURNAL OF NUTRITION

Quercetin Enhances Chemosensitivity to Gemcitabine in Lung Cancer Cells by Inhibiting Heat Shock Protein 70 Expression

(2015) Seung Hyeun Lee et al.   Clinical Lung Cancer

The JNK Signaling Pathway Is a Novel Molecular Target for S-Propargyl- L-Cysteine, a Naturally-Occurring Garlic Derivatives: Link to Its Anticancer Activity in Pancreatic Cancer In Vitro and In Vivo

(2015) Wei Wang et al.   CURRENT CANCER DRUG TARGETS

Allium cepaL. and Quercetin Inhibit RANKL/Porphyromonas gingivalisLPS-Induced Osteoclastogenesis by Downregulating NF-κB Signaling Pathway

(2015) Tatiane Oliveira et al.   Evidence-based Complementary and Alternative Medicine

Identification and Quantification of Flavonoids from Two Southern Italian Cultivars of Allium cepa L., Tropea (Red Onion) and Montoro (Copper Onion), and Their Capacity to Protect Human Erythrocytes from Oxidative Stress

(2015) Idolo Tedesco et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Allium Discoloration: Color Compounds Formed during Pinking of Onion and Leek

(2015) Roman Kubec et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Therapeutic administration of an ingredient of aged-garlic extracts, S-allyl cysteine resolves liver fibrosis established by carbon tetrachloride in rats

(2015) Shintaro Kodai et al.   JOURNAL OF CLINICAL BIOCHEMISTRY AND NUTRITION

s-Ethyl Cysteine ands-Methyl Cysteine Protect Human Bronchial Epithelial Cells Against Hydrogen Peroxide Induced Injury

(2015) Te-chun Hsia et al.   JOURNAL OF FOOD SCIENCE

A Single Meal Containing Raw, Crushed Garlic Influences Expression of Immunity- and Cancer-Related Genes in Whole Blood of Humans

(2015) Craig S Charron et al.   JOURNAL OF NUTRITION

Analysis of lifespan-promoting effect of garlic extract by an integrated metabolo-proteomics approach

(2015) Chun-Hao Huang et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Prevention of Cardiovascular Diseases by Garlic-Derived Sulfur Compounds

(2015) Taiichiro SEKI et al.   JOURNAL OF NUTRITIONAL SCIENCE AND VITAMINOLOGY

Relation of allium vegetables intake with head and neck cancers: Evidence from the INHANCE consortium

(2015) Carlotta Galeone et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Decreased glycation and structural protection properties of γ-glutamyl-S-allyl-cysteine peptide isolated from fresh garlic scales (Allium sativumL.)

(2015) Dehong Tan et al.   NATURAL PRODUCT RESEARCH

Post-injury administration of allicin attenuates ischemic brain injury through sphingosine kinase 2: In vivo and in vitro studies

(2015) Jia-Ji Lin et al.   NEUROCHEMISTRY INTERNATIONAL

On the antioxidant, neuroprotective and anti-inflammatory properties of S-allyl cysteine: An update

(2015) Ana Laura Colín-González et al.   NEUROCHEMISTRY INTERNATIONAL

Effect of onion peel extract on endothelial function and endothelial progenitor cells in overweight and obese individuals

(2015) Eun-Yong Choi et al.   NUTRITION

Cardioprotective Efficacy of Red Wine Extract of Onion in Healthy Hypercholesterolemic Subjects

(2015) Hui-Fang Chiu et al.   PHYTOTHERAPY RESEARCH

Hypocholesterolemic Efficacy of Quercetin Rich Onion Juice in Healthy Mild Hypercholesterolemic Adults: A Pilot Study

(2015) Tsong-Ming Lu et al.   PLANT FOODS FOR HUMAN NUTRITION

Identification of a flavin-containingS-oxygenating monooxygenase involved in alliin biosynthesis in garlic

(2015) Naoko Yoshimoto et al.   PLANT JOURNAL

Ethanolic Extract of Allium cepa Stimulates Glucose Transporter Typ 4-Mediated Glucose Uptake by the Activation of Insulin Signaling

(2015) Sudeep Gautam et al.   PLANTA MEDICA

Depletion of H2S during obesity enhances store-operated Ca2+entry in adipose tissue macrophages to increase cytokine production

(2015) Gopal V. Velmurugan et al.   Science Signaling

Spirostanol steroids from the roots of Allium tuberosum

(2015) Yun-Shan Fang et al.   STEROIDS

Garlic-derived compound S-allylmercaptocysteine (SAMC) is active against anaplastic thyroid cancer cell line 8305C (HPACC)

(2015) Yuexin Liu et al.   TECHNOLOGY AND HEALTH CARE

Interaction of Quercetin of Onion with Axon Guidance Protein Receptor, NRP-1 Plays Important Role in Cancer Treatment: An In Silico Approach

(2015) Tahirah Yasmin et al.   Interdisciplinary Sciences-Computational Life Sciences

Depletion of H2S during obesity enhances store-operated Ca2+entry in adipose tissue macrophages to increase cytokine production

(2015) Gopal V. Velmurugan et al.   Science Signaling

A review on the effects of Allium sativum (Garlic) in metabolic syndrome

(2015) A. Hosseini et al.   JOURNAL OF ENDOCRINOLOGICAL INVESTIGATION

Immunomodulation and Anti-Inflammatory Effects of Garlic Compounds

(2015) Rodrigo Arreola et al.   Journal of Immunology Research

Novel quercetin-3-O-glucoside eicosapentaenoic acid ester ameliorates inflammation and hyperlipidemia

(2015) Satvir Sekhon-Loodu et al.   INFLAMMOPHARMACOLOGY

Hydrogen sulfide-mediated cardioprotection: mechanisms and therapeutic potential

(2015) Madhav Lavu et al.   CLINICAL SCIENCE

De Novo Assembly and Annotation of the Chinese Chive (Allium tuberosum Rottler ex Spr.) Transcriptome Using the Illumina Platform

(2015) Shu-Mei Zhou et al.   PLoS One

S-benzyl-cysteine-mediated Cell Cycle Arrest and Apoptosis Involving Activation of Mitochondrial-dependent Caspase Cascade through the p53 Pathway in Human Gastric Cancer SGC-7901 Cells

(2014) Hua-Jun Sun et al.   Asian Pacific Journal of Cancer Prevention

Antitumor mechanisms of S-allyl mercaptocysteine for breast cancer therapy

(2014) Hong Zhang et al.   BMC Complementary and Alternative Medicine

Inhibitory effect of liposomal quercetin on acute hepatitis and hepatic fibrosis induced by concanavalin A

(2014) Y. Wan et al.   BRAZILIAN JOURNAL OF MEDICAL AND BIOLOGICAL RESEARCH

Evaluation of TNF-α serum level in patients with recalcitrant multiple common warts, treated by lipid garlic extract

(2014) Soha Kenawy et al.   Dermatologic Therapy

Role of JNK Activation and Mitochondrial Bax Translocation in Allicin-Induced Apoptosis in Human Ovarian Cancer SKOV3 Cells

(2014) Ling Xu et al.   Evidence-based Complementary and Alternative Medicine

Furostanol saponins from the seeds of Allium cepa L.

(2014) Chuang-Jun Li et al.   FITOTERAPIA

Neuroprotective effects of Z-ajoene, an organosulfur compound derived from oil-macerated garlic, in the gerbil hippocampal CA1 region after transient forebrain ischemia

(2014) Dae Young Yoo et al.   FOOD AND CHEMICAL TOXICOLOGY

Vasodilatory activity of human quercitin metabolites

(2014) Iveta Najmanová et al.   FREE RADICAL BIOLOGY AND MEDICINE

In vivo effects of dietary quercetin and quercetin-rich red onion extract on skeletal muscle mitochondria, metabolism, and insulin sensitivity

(2014) T. M. Henagan et al.   Genes and Nutrition

Garlic Essential Oil Protects against Obesity-Triggered Nonalcoholic Fatty Liver Disease through Modulation of Lipid Metabolism and Oxidative Stress

(2014) Yi-Syuan Lai et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Functional components and medicinal properties of food: a review

(2014) Christian Izuchukwu Abuajah et al.   JOURNAL OF FOOD SCIENCE AND TECHNOLOGY-MYSORE

Beneficial effect of quercetin on cholestatic liver injury

(2014) Shih-Yi Lin et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

The effects of diallyl sulfide uponPorphyromonas gingivalislipopolysaccharide stimulated proinflammatory cytokine expressions and nuclear factor-kappa B activation in human gingival fibroblasts

(2014) E. Fu et al.   JOURNAL OF PERIODONTAL RESEARCH

Onion extract (Allium cepaL.), quercetin and catechin up-regulate paraoxonase 1 activity with concomitant protection against low-density lipoprotein oxidation in male Wistar rats subjected to oxidative stress

(2014) Nidhi Jaiswal et al.   JOURNAL OF THE SCIENCE OF FOOD AND AGRICULTURE

Quercetin-rich onion peel extract suppresses adipogenesis by down-regulating adipogenic transcription factors and gene expression in 3T3-L1 adipocytes

(2014) Cho-Rong Bae et al.   JOURNAL OF THE SCIENCE OF FOOD AND AGRICULTURE

Allicin induces apoptosis of the MGC-803 human gastric carcinoma cell line through the p38 mitogen-activated protein kinase/caspase-3 signaling pathway

(2014) XUECHENG ZHANG et al.   Molecular Medicine Reports

Evaluating the Anti-Neuroinflammatory Capacity of Raw and Steamed Garlic as Well as Five Organosulfur Compounds

(2014) Su-Chen Ho et al.   MOLECULES

Allicin: Chemistry and Biological Properties

(2014) Jan Borlinghaus et al.   MOLECULES

Chemical Composition, Antibacterial and Antioxidant Activities of Six Essentials Oils from the Alliaceae Family

(2014) Dima Mnayer et al.   MOLECULES

Systemic Approaches Identify a Garlic-Derived Chemical, Z-ajoene, as a Glioblastoma Multiforme Cancer Stem Cell-Specific Targeting Agent

(2014) Yuchae Jung et al.   MOLECULES AND CELLS

Spice plant Allium cepa: Dietary supplement for treatment of type 2 diabetes mellitus

(2014) Muhammad Sajid Hamid Akash et al.   NUTRITION

Proteomic Analysis of the Effects of Aged Garlic Extract and Its FruArg Component on Lipopolysaccharide-Induced Neuroinflammatory Response in Microglial Cells

(2014) Hui Zhou et al.   PLoS One

Garlic Revisited: Antimicrobial Activity of Allicin-Containing Garlic Extracts against Burkholderia cepacia Complex

(2014) Daynea Wallock-Richards et al.   PLoS One

Fistular onion stalk extract exhibits anti-atherosclerotic effects in rats

(2014) BENHONG HE et al.   Experimental and Therapeutic Medicine

s-Methyl cysteine enhanced survival of nerve growth factor differentiated PC12 cells under hypoxic conditions

(2014) Chun-lin Liu et al.   Food & Function

Protective effect of S-allyl-l-cysteine against endoplasmic reticulum stress-induced neuronal death is mediated by inhibition of calpain

(2013) Toru Imai et al.   AMINO ACIDS

Garlic and cardioprotection: insights into the molecular mechanisms

(2013) Tarak Nath Khatua et al.   CANADIAN JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY

Protective effects of garlic extract on cardiac function, heart rate variability, and cardiac mitochondria in obese insulin-resistant rats

(2013) Luerat Supakul et al.   EUROPEAN JOURNAL OF NUTRITION

Cytotoxic and anti-inflammatory effects of onion peel extract on lipopolysaccharide stimulated human colon carcinoma cells

(2013) Jungmi Kim et al.   FOOD AND CHEMICAL TOXICOLOGY

Antiobesity effects of quercetin-rich onion peel extract on the differentiation of 3T3-L1 preadipocytes and the adipogenesis in high fat-fed rats

(2013) Jiyoung Moon et al.   FOOD AND CHEMICAL TOXICOLOGY

Synthetic polysulfane derivatives induce cell cycle arrest and apoptotic cell death in human hematopoietic cancer cells

(2013) Brigitte Czepukojc et al.   FOOD AND CHEMICAL TOXICOLOGY

Spirostane, furostane and cholestane saponins from Persian leek with antifungal activity

(2013) Masoud Sadeghi et al.   FOOD CHEMISTRY

Garlic intake is an independent predictor of endothelial function in patients with ischemic stroke

(2013) K. -K. Lau et al.   Journal of Nutrition Health & Aging

Inhibitory effects and molecular mechanisms of garlic organosulfur compounds on the production of inflammatory mediators

(2013) Sixiang You et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Site-Specific Anticancer Effects of Dietary Flavonoid Quercetin

(2013) Katrin Sak   NUTRITION AND CANCER-AN INTERNATIONAL JOURNAL

Role of Di-allyl Disulfide, a Garlic Component in NF-κB Mediated Transient G2-M Phase Arrest and Apoptosis in Human Leukemic Cell-lines

(2013) Pritha Dasgupta et al.   NUTRITION AND CANCER-AN INTERNATIONAL JOURNAL

Anti-Wrinkle and Anti-Inflammatory Effects of Active Garlic Components and the Inhibition of MMPs via NF-κB Signaling

(2013) So Ra Kim et al.   PLoS One

Evaluation of Garlic Cultivars for Polyphenolic Content and Antioxidant Properties

(2013) Shuxia Chen et al.   PLoS One

Diallyl disulfide impairs hippocampal neurogenesis in the young adult brain

(2013) Seung Taek Ji et al.   TOXICOLOGY LETTERS

Effect of Allium cepa and Allium sativum on some immunological cells in rats

(2012) TY Mirabeau et al.   African Journal of Traditional Complementary and Alternative Medicines

Polychlorinated biphenyls impair blood–brain barrier integrity via disruption of tight junction proteins in cerebrum, cerebellum and hippocampus of female Wistar rats

(2012) K. Selvakumar et al.   HUMAN & EXPERIMENTAL TOXICOLOGY

Effect of Processing and Cooking Conditions on Onion (Allium cepa L.) Induced Antiplatelet Activity and Thiosulfinate Content

(2012) Pablo F. Cavagnaro et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Antidiabetic effect of S-allylcysteine: Effect on Thyroid hormone and circulatory antioxidant system in experimental diabetic rats

(2012) Ganapathy Saravanan et al.   JOURNAL OF DIABETES AND ITS COMPLICATIONS

Onion (Allium cepa) extract attenuates brain edema

(2012) Soo-Wang Hyun et al.   NUTRITION

Antifungal saponins from bulbs of garlic, Allium sativum L. var. Voghiera

(2012) Virginia Lanzotti et al.   PHYTOCHEMISTRY

Diallyl sulfide, diallyl disulfide and diallyl trisulfide affect drug resistant gene expression in colo 205 human colon cancer cells in vitro and in vivo

(2012) Kuang-Chi Lai et al.   PHYTOMEDICINE

The Role of Diallyl Sulfides and Dipropyl Sulfides in theIn VitroAntimicrobial Activity of the Essential Oil of Garlic,Allium sativumL., and Leek,Allium porrumL.

(2012) Sergio Casella et al.   PHYTOTHERAPY RESEARCH

The biology of reactive sulfur species (RSS)

(2012) Martin C.H. Gruhlke et al.   PLANT PHYSIOLOGY AND BIOCHEMISTRY

Effect of garlic on high fat induced obesity

(2011) M. Kim et al.   ACTA BIOLOGICA HUNGARICA

Functional characterization of the recombinant antimicrobial peptide Trx-Ace-AMP1 and its application on the control of tomato early blight disease

(2011) Yin Wu et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

The antioxidant effects of garlic saponins protect PC12 cells from hypoxia-induced damage

(2011) Hong Luo et al.   BRITISH JOURNAL OF NUTRITION

Antimicrobial properties of allium species

(2011) Kyu Hang Kyung   CURRENT OPINION IN BIOTECHNOLOGY

Consumption of Large Amounts of Allium Vegetables Reduces Risk for Gastric Cancer in a Meta-analysis

(2011) Yong Zhou et al.   GASTROENTEROLOGY

Carotenoid Accumulation and Characterization of cDNAs Encoding Phytoene Synthase and Phytoene Desaturase in Garlic (Allium sativum)

(2011) Pham Anh Tuan et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Neuroprotective effects of diallyl trisulfide in SOD1-G93A transgenic mouse model of amyotrophic lateral sclerosis

(2010) Yansu Guo et al.   BRAIN RESEARCH

S-Allyl-Mercapto-Captopril: A Novel Compound in the Treatment of Cohen-Rosenthal Diabetic Hypertensive Rats

(2010) Firas Younis et al.   Journal of Clinical Hypertension

Methanolic extract of onion (Allium cepa) attenuates ischemia/hypoxia-induced apoptosis in cardiomyocytes via antioxidant effect

(2009) Sok Park et al.   EUROPEAN JOURNAL OF NUTRITION

The Antidiabetic Effect of Onion and Garlic in Experimental Diabetic Rats: Meta-Analysis

(2009) Sejeong Kook et al.   JOURNAL OF MEDICINAL FOOD

Mechanisms of thiosulfinates from Allium tuberosum L.-induced apoptosis in HT-29 human colon cancer cells

(2009) Ju-Hye Lee et al.   TOXICOLOGY LETTERS

Allyl mercaptan, a garlic-derived organosulfur compound, inhibits histone deacetylase and enhances Sp3 binding on the P21WAF1 promoter

(2008) H. Nian et al.   CARCINOGENESIS