The Sweet Side of Immune Evasion: Role of Glycans in the Mechanisms of Cancer Progression

Tumor microenvironment (TME)-driven immune suppression in B cell malignancy

(2016) Nicole S. Nicholas et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

The cancer glycome: Carbohydrates as mediators of metastasis

(2015) Siobhan V. Glavey et al.   BLOOD REVIEWS

Immune checkpoint inhibition in lymphoid disease

(2015) Toby A. Eyre et al.   BRITISH JOURNAL OF HAEMATOLOGY

Sialic acids in cancer biology and immunity

(2015) Oliver M T Pearce et al.   GLYCOBIOLOGY

Immunosuppressive cells in tumor immune escape and metastasis

(2015) Yang Liu et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

Immune evasion in cancer: Mechanistic basis and therapeutic strategies

(2015) Dass S. Vinay et al.   SEMINARS IN CANCER BIOLOGY

Novel Immune Check-Point Regulators in Tolerance Maintenance

(2015) Yanxia Guo et al.   Frontiers in Immunology

The Role of Glycosylation in Breast Cancer Metastasis and Cancer Control

(2015) Alexandra C. Kölbl et al.   Frontiers in Oncology

Sweet escape: Sialic acids in tumor immune evasion

(2014) Christian Büll et al.   BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER

Glycans in immune recognition and response

(2014) Ron Amon et al.   CARBOHYDRATE RESEARCH

Cancer intelligence acquired (CIA): tumor glycosylation and sialylation codes dismantling antitumor defense

(2014) Kayluz Frias Boligan et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Interactions between Siglec-7/9 receptors and ligands influence NK cell–dependent tumor immunosurveillance

(2014) Camilla Jandus et al.   JOURNAL OF CLINICAL INVESTIGATION

Knockdown of Mgat5 Inhibits Breast Cancer Cell Growth with Activation of CD4+ T Cells and Macrophages

(2014) D. Li et al.   JOURNAL OF IMMUNOLOGY

Engagement of myelomonocytic Siglecs by tumor-associated ligands modulates the innate immune response to cancer

(2014) Heinz Läubli et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Inverse hormesis of cancer growth mediated by narrow ranges of tumor-directed antibodies

(2014) O. M. T. Pearce et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A red meat-derived glycan promotes inflammation and cancer progression

(2014) Annie N. Samraj et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Aberrant Glycosylation Promotes Lung Cancer Metastasis through Adhesion to Galectins in the Metastatic Niche

(2014) Nathan E. Reticker-Flynn et al.   Cancer Discovery

Altered Tumor-Cell Glycosylation Promotes Metastasis

(2014) Irina Häuselmann et al.   Frontiers in Oncology

Involvement of a Non-Human Sialic Acid in Human Cancer

(2014) Annie N. Samraj et al.   Frontiers in Oncology

Sweet and Sour: The Impact of Differential Glycosylation in Cancer Cells Undergoing Epithelial–Mesenchymal Transition

(2014) Leonardo Freire-de-Lima   Frontiers in Oncology

NK cell-based immunotherapy for malignant diseases

(2013) Min Cheng et al.   Cellular & Molecular Immunology

Multifarious roles of sialic acids in immunity

(2012) Ajit Varki et al.   Annals of the New York Academy of Sciences

Siglecs and Immune Regulation

(2012) Shiv Pillai et al.   Annual Review of Immunology

Tumor Defense Systems Using O-Glycans

(2012) Shigeru Tsuboi   BIOLOGICAL & PHARMACEUTICAL BULLETIN

Regulation of the metastatic cell phenotype by sialylated glycans

(2012) Matthew J. Schultz et al.   CANCER AND METASTASIS REVIEWS

Molecular Identification of GD3 as a Suppressor of the Innate Immune Response in Ovarian Cancer

(2012) T. J. Webb et al.   CANCER RESEARCH

The interaction between Siglec-15 and tumor-associated sialyl-Tn antigen enhances TGF-  secretion from monocytes/macrophages through the DAP12-Syk pathway

(2012) R. Takamiya et al.   GLYCOBIOLOGY

Aberrantly glycosylated MUC1 is expressed on the surface of breast cancer cells and a target for antibody-dependent cell-mediated cytotoxicity

(2012) Kirstine Lavrsen et al.   GLYCOCONJUGATE JOURNAL

Carbohydrate to carbohydrate interaction in development process and cancer progression

(2012) Kazuko Handa et al.   GLYCOCONJUGATE JOURNAL

MUC1 carrying core 2 O-glycans functions as a molecular shield against NK cell attack, promoting bladder tumor metastasis

(2012) Shigeru Tsuboi   INTERNATIONAL JOURNAL OF ONCOLOGY

Ganglioside Inhibition of CD8+ T Cell Cytotoxicity: Interference with Lytic Granule Trafficking and Exocytosis

(2012) H. C. Lee et al.   JOURNAL OF IMMUNOLOGY

Core2 O-glycan-expressing prostate cancer cells are resistant to NK cell immunity

(2012) TEPPEI OKAMOTO et al.   Molecular Medicine Reports

Vertebrate protein glycosylation: diversity, synthesis and function

(2012) Kelley W. Moremen et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Two opposing roles of O-glycans in tumor metastasis

(2012) Shigeru Tsuboi et al.   TRENDS IN MOLECULAR MEDICINE

Cell surface glycan–lectin interactions in tumor metastasis

(2011) Neela D.S. Rambaruth et al.   ACTA HISTOCHEMICA

Mechanisms and principles of N-linked protein glycosylation

(2011) Flavio Schwarz et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

Letter to the Glyco-Forum: Since there are PAMPs and DAMPs, there must be SAMPs? Glycan "self-associated molecular patterns" dampen innate immunity, but pathogens can mimic them

(2011) A. Varki   GLYCOBIOLOGY

Sialylation of the Fas Death Receptor by ST6Gal-I Provides Protection against Fas-mediated Apoptosis in Colon Carcinoma Cells

(2011) Amanda F. Swindall et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

DC-SIGN and SRCL bind glycans of carcinoembryonic antigen (CEA) and CEA-related cell adhesion molecule 1 (CEACAM1): recombinant human glycan-binding receptors as analytical tools

(2010) Alexandra Samsen et al.   EUROPEAN JOURNAL OF CELL BIOLOGY

Ganglioside-exposed dendritic cells inhibit T-cell effector function by promoting regulatory cell activity

(2010) Alessandra Jales et al.   IMMUNOLOGY

Bridging Innate and Adaptive Antitumor Immunity Targeting Glycans

(2010) Anastas Pashov et al.   JOURNAL OF BIOMEDICINE AND BIOTECHNOLOGY

Sialylation of 3-Methylcholanthrene-Induced Fibrosarcoma Determines Antitumor Immune Responses during Immunoediting

(2010) M. Cohen et al.   JOURNAL OF IMMUNOLOGY

Complement: a key system for immune surveillance and homeostasis

(2010) Daniel Ricklin et al.   NATURE IMMUNOLOGY

Molecular mimicry of host sialylated glycans allows a bacterial pathogen to engage neutrophil Siglec-9 and dampen the innate immune response

(2009) A. F. Carlin et al.   BLOOD

E-/P-selectins and colon carcinoma metastasis: first in vivo evidence for their crucial role in a clinically relevant model of spontaneous metastasis formation in the lung

(2009) S Köhler et al.   BRITISH JOURNAL OF CANCER

Altered expression of glycan genes in cancers induced by epigenetic silencing and tumor hypoxia: Clues in the ongoing search for new tumor markers

(2009) Reiji Kannagi et al.   CANCER SCIENCE

Sialic acids acquired byPseudomonas aeruginosaare involved in reduced complement deposition and siglec mediated host-cell recognition

(2009) Biswajit Khatua et al.   FEBS LETTERS

Suppression of Autoimmune Diabetes by Soluble Galectin-1

(2009) M. J. Perone et al.   JOURNAL OF IMMUNOLOGY

Immune surveillance and immunotherapy: Lessons from carbohydrate mimotopes

(2009) Anastas Pashov et al.   VACCINE

Altered Glycosylation of Proteins in Cancer: What Is the Potential for New Anti-Tumour Strategies

(2008) S. Brooks et al.   Anti-Cancer Agents in Medicinal Chemistry

Biological Modulation by Lectins and Their Ligands in Tumor Progression and Metastasis

(2008) Avraham Raz et al.   Anti-Cancer Agents in Medicinal Chemistry

Restoring the Association of the T Cell Receptor with CD8 Reverses Anergy in Human Tumor-Infiltrating Lymphocytes

(2008) Nathalie Demotte et al.   IMMUNITY

Fine specificity of natural killer T cells against GD3 ganglioside and identification of GM3 as an inhibitory natural killer T-cell ligand

(2008) Jun-Eui Park et al.   IMMUNOLOGY

The Immune System — is it Relevant to Cancer Development, Progression and Treatment?

(2007) R.J. Prestwich et al.   CLINICAL ONCOLOGY