Intrinsic and Tumor Microenvironment-Induced Metabolism Adaptations of T Cells and Impact on Their Differentiation and Function
Published 2016 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Intrinsic and Tumor Microenvironment-Induced Metabolism Adaptations of T Cells and Impact on Their Differentiation and Function
Authors
Keywords
-
Journal
Frontiers in Immunology
Volume 7, Issue -, Pages -
Publisher
Frontiers Media SA
Online
2016-03-29
DOI
10.3389/fimmu.2016.00114
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Targeting hypoxic response for cancer therapy
- (2016) Elisa Paolicchi et al. Oncotarget
- Hypoxia: a key player in antitumor immune response. A Review in the Theme: Cellular Responses to Hypoxia
- (2015) Muhammad Zaeem Noman et al. AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY
- Interactions between Myc and MondoA transcription factors in metabolism and tumourigenesis
- (2015) Blake R Wilde et al. BRITISH JOURNAL OF CANCER
- Immune Regulation of Metabolic Homeostasis in Health and Disease
- (2015) Jonathan R. Brestoff et al. CELL
- mTOR coordinates protein synthesis, mitochondrial activity and proliferation
- (2015) Masahiro Morita et al. CELL CYCLE
- Nutrient and immune sensing are obligate pathways in metabolism, immunity, and disease
- (2015) Abishek Iyer et al. FASEB JOURNAL
- Metabolic Reprogramming of Immune Cells in Cancer Progression
- (2015) Subhra K. Biswas IMMUNITY
- The Cellular and Molecular Basis of Translational Immunometabolism
- (2015) Giuseppe Danilo Norata et al. IMMUNITY
- Signaling through the Phosphatidylinositol 3-Kinase (PI3K)/Mammalian Target of Rapamycin (mTOR) Axis Is Responsible for Aerobic Glycolysis mediated by Glucose Transporter in Epidermal Growth Factor Receptor (EGFR)-mutated Lung Adenocarcinoma
- (2015) Hideki Makinoshima et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- T cell metabolism drives immunity
- (2015) Michael D. Buck et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Programmed Death-1 Controls T Cell Survival by Regulating Oxidative Metabolism
- (2015) Victor Tkachev et al. JOURNAL OF IMMUNOLOGY
- Understanding the Mysterious M2 Macrophage through Activation Markers and Effector Mechanisms
- (2015) Tamás Rőszer MEDIATORS OF INFLAMMATION
- Assembling the T cell
- (2015) Grant Miura Nature Chemical Biology
- Immune Response Regulation in the Tumor Microenvironment by Hypoxia
- (2015) Sara Labiano et al. SEMINARS IN ONCOLOGY
- Targeting T cell metabolism for therapy
- (2015) David O'Sullivan et al. TRENDS IN IMMUNOLOGY
- PD-1 alters T-cell metabolic reprogramming by inhibiting glycolysis and promoting lipolysis and fatty acid oxidation
- (2015) Nikolaos Patsoukis et al. Nature Communications
- Special Conference on Tumor Immunology and Immunotherapy: A New Chapter
- (2015) K. T. Byrne et al. Cancer Immunology Research
- Tumor Immunology, toward a Success Story?
- (2015) Catherine Sautès-Fridman Frontiers in Immunology
- Environmental and Metabolic Sensors That Control T Cell Biology
- (2015) George Ramsay et al. Frontiers in Immunology
- Glutaminase: A Hot Spot For Regulation Of Cancer Cell Metabolism?
- (2015) Oncotarget
- Dysfunctional oxidative phosphorylation makes malignant melanoma cells addicted to glycolysis driven by the V600EBRAF oncogene
- (2015) Arnaldur Hall et al. Oncotarget
- Development of PD-1/PD-L1 Pathway in Tumor Immune Microenvironment and Treatment for Non-Small Cell Lung Cancer
- (2015) Jiabei He et al. Scientific Reports
- 2-Deoxy-D-glucose targeting of glucose metabolism in cancer cells as a potential therapy
- (2014) Dongsheng Zhang et al. CANCER LETTERS
- Immune-Based Antitumor Effects of BRAF Inhibitors Rely on Signaling by CD40L and IFN
- (2014) P.-C. Ho et al. CANCER RESEARCH
- Host Immune Response to Infection and Cancer: Unexpected Commonalities
- (2014) Romina S. Goldszmid et al. Cell Host & Microbe
- The Glucose Transporter Glut1 Is Selectively Essential for CD4 T Cell Activation and Effector Function
- (2014) Andrew N. Macintyre et al. Cell Metabolism
- Immune Escape Mechanisms as a Guide for Cancer Immunotherapy
- (2014) G. L. Beatty et al. CLINICAL CANCER RESEARCH
- Adipose tissue macrophages: the inflammatory link between obesity and cancer?
- (2014) Marek Wagner et al. EXPERT OPINION ON THERAPEUTIC TARGETS
- Mitochondrial Metabolism in T Cell Activation and Senescence: A Mini-Review
- (2014) Noga Ron-Harel et al. GERONTOLOGY
- Macrophages, Immunity, and Metabolic Disease
- (2014) Joanne C. McNelis et al. IMMUNITY
- Obesity and Its Metabolic Complications: The Role of Adipokines and the Relationship between Obesity, Inflammation, Insulin Resistance, Dyslipidemia and Nonalcoholic Fatty Liver Disease
- (2014) Un Jung et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Metabolic Mysteries of the Inflammatory Response: T Cell Polarization and Plasticity
- (2014) Kelley M. Fracchia et al. INTERNATIONAL REVIEWS OF IMMUNOLOGY
- Akt-dependent Activation of mTORC1 Complex Involves Phosphorylation of mTOR (Mammalian Target of Rapamycin) by IκB Kinase α (IKKα)
- (2014) Han C. Dan et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Interplay between the immune system and adipose tissue in obesity
- (2014) Mark A Exley et al. JOURNAL OF ENDOCRINOLOGY
- Glucose Uptake Is Limiting in T Cell Activation and Requires CD28-Mediated Akt-Dependent and Independent Pathways
- (2014) S. R. Jacobs et al. JOURNAL OF IMMUNOLOGY
- Tumor-Secreted Lactic Acid Promotes IL-23/IL-17 Proinflammatory Pathway
- (2014) H. Shime et al. JOURNAL OF IMMUNOLOGY
- Crosstalk between Adipocytes and Immune Cells in Adipose Tissue Inflammation and Metabolic Dysregulation in Obesity
- (2014) Jin Young Huh et al. MOLECULES AND CELLS
- Tumor endothelium FasL establishes a selective immune barrier promoting tolerance in tumors
- (2014) Gregory T Motz et al. NATURE MEDICINE
- Regulation of the pentose phosphate pathway in cancer
- (2014) Peng Jiang et al. Protein & Cell
- Regulation of the pentose phosphate pathway by an androgen receptor–mTOR-mediated mechanism and its role in prostate cancer cell growth
- (2014) E Tsouko et al. Oncogenesis
- Metabolic Regulation of Regulatory T Cell Development and Function
- (2014) David John Coe et al. Frontiers in Immunology
- Metabolic Regulation of T Lymphocytes
- (2013) Nancie J. MacIver et al. Annual Review of Immunology
- Host programmed death ligand 1 is dominant over programmed death ligand 2 expression in regulating graft-versus-host disease lethality
- (2013) A. Saha et al. BLOOD
- Oncogenic BRAF Regulates Oxidative Metabolism via PGC1α and MITF
- (2013) Rizwan Haq et al. CANCER CELL
- A Mechanism of Hypoxia-Mediated Escape from Adaptive Immunity in Cancer Cells
- (2013) I. B. Barsoum et al. CANCER RESEARCH
- Improved Insulin Sensitivity despite Increased Visceral Adiposity in Mice Deficient for the Immune Cell Transcription Factor T-bet
- (2013) Emilie Stolarczyk et al. Cell Metabolism
- Adipose Tissue Macrophages Function As Antigen-Presenting Cells and Regulate Adipose Tissue CD4 + T Cells in Mice
- (2013) David L. Morris et al. DIABETES
- Two p53-related metabolic regulators, TIGAR and SCO2, contribute to oroxylin A-mediated glucose metabolism in human hepatoma HepG2 cells
- (2013) Qinsheng Dai et al. INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY
- Macrophages, fat, and the emergence of immunometabolism
- (2013) Anthony W. Ferrante JOURNAL OF CLINICAL INVESTIGATION
- HIF-1 mediates metabolic responses to intratumoral hypoxia and oncogenic mutations
- (2013) Gregg L. Semenza JOURNAL OF CLINICAL INVESTIGATION
- Intestinal monocytes and macrophages are required for T cell polarization in response toCitrobacter rodentium
- (2013) Heidi A. Schreiber et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Leptin–cytokine crosstalk in breast cancer
- (2013) Gale Newman et al. MOLECULAR AND CELLULAR ENDOCRINOLOGY
- Tumor glycolysis as a target for cancer therapy: progress and prospects
- (2013) Shanmugasundaram Ganapathy-Kanniappan et al. Molecular Cancer
- Metabolism of inflammation limited by AMPK and pseudo-starvation
- (2013) Luke A. J. O'Neill et al. NATURE
- Hypoxia-inducible factors enhance the effector responses of CD8+ T cells to persistent antigen
- (2013) Andrew L Doedens et al. NATURE IMMUNOLOGY
- Adipocytes: Impact on tumor growth and potential sites for therapeutic intervention
- (2013) Simona Hefetz-Sela et al. PHARMACOLOGY & THERAPEUTICS
- Fueling Immunity: Insights into Metabolism and Lymphocyte Function
- (2013) E. L. Pearce et al. SCIENCE
- Chronic adipose tissue inflammation: all immune cells on the stage
- (2013) Gökhan Cildir et al. TRENDS IN MOLECULAR MEDICINE
- Oncogenic role and therapeutic target of leptin signaling in breast cancer and cancer stem cells
- (2012) Shanchun Guo et al. BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER
- Metabolic Reprogramming: A Cancer Hallmark Even Warburg Did Not Anticipate
- (2012) Patrick S. Ward et al. CANCER CELL
- T-Regulatory Cells: Key Players in Tumor Immune Escape and Angiogenesis
- (2012) A. Facciabene et al. CANCER RESEARCH
- Distinct metabolic programs in activated T cells: opportunities for selective immunomodulation
- (2012) Daniel R. Wahl et al. IMMUNOLOGICAL REVIEWS
- Molecular mechanisms of metabolic reprogramming in proliferating cells: implications for T-cell-mediated immunity
- (2012) Federica M. Marelli-Berg et al. IMMUNOLOGY
- Case Report: Sodium dichloroacetate (DCA) inhibition of the “Warburg Effect” in a human cancer patient: complete response in non-Hodgkin’s lymphoma after disease progression with rituximab-CHOP
- (2012) Stephen B. Strum et al. JOURNAL OF BIOENERGETICS AND BIOMEMBRANES
- Metabolic checkpoints in activated T cells
- (2012) Ruoning Wang et al. NATURE IMMUNOLOGY
- The cellular and signaling networks linking the immune system and metabolism in disease
- (2012) Olivia Osborn et al. NATURE MEDICINE
- Hypoxia-inducible factor-1 alpha-dependent induction of FoxP3 drives regulatory T-cell abundance and function during inflammatory hypoxia of the mucosa
- (2012) E. T. Clambey et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- What are regulatory T cells (Treg) regulating in cancer and why?
- (2012) Theresa L. Whiteside SEMINARS IN CANCER BIOLOGY
- The regulation of cancer cell death and metabolism by extracellular matrix attachment
- (2012) Cassandra L. Buchheit et al. SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY
- Cancer Cell Metabolism: One Hallmark, Many Faces
- (2012) Jason R. Cantor et al. Cancer Discovery
- Aerobic Glycolysis: Meeting the Metabolic Requirements of Cell Proliferation
- (2011) Sophia Y. Lunt et al. Annual Review of Cell and Developmental Biology
- Control of TH17/Treg Balance by Hypoxia-Inducible Factor 1
- (2011) Eric V. Dang et al. CELL
- Hallmarks of Cancer: The Next Generation
- (2011) Douglas Hanahan et al. CELL
- mTOR inhibition in breast cancer: unraveling the complex mechanisms of mTOR signal transduction and its clinical implications in therapy
- (2011) Ruth O'Regan et al. EXPERT OPINION ON THERAPEUTIC TARGETS
- HIF1α–dependent glycolytic pathway orchestrates a metabolic checkpoint for the differentiation of TH17 and Tregcells
- (2011) Lewis Z. Shi et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Editorial: Switching on arginase in M2 macrophages
- (2011) Volker Briken et al. JOURNAL OF LEUKOCYTE BIOLOGY
- The multifactorial role of leptin in driving the breast cancer microenvironment
- (2011) Sebastiano Andò et al. Nature Reviews Endocrinology
- Fats, inflammation and insulin resistance: insights to the role of macrophage and T-cell accumulation in adipose tissue
- (2011) Karen A. Harford et al. PROCEEDINGS OF THE NUTRITION SOCIETY
- α5β1-Integrin Expression Is Essential for Tumor Progression in Experimental Lung Cancer
- (2010) Jesse Roman et al. AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY
- Regulatory T cells and breast cancer: implications for immunopathogenesis
- (2010) Maria Angelica Ehara Watanabe et al. CANCER AND METASTASIS REVIEWS
- Immunity, Inflammation, and Cancer
- (2010) Sergei I. Grivennikov et al. CELL
- mTOR signalling and metabolic regulation of T cell differentiation
- (2010) Christian Peter et al. CURRENT OPINION IN IMMUNOLOGY
- The Mammalian Target of Rapamycin: Linking T Cell Differentiation, Function, and Metabolism
- (2010) Jonathan D. Powell et al. IMMUNITY
- Glutamine Uptake and Metabolism Are Coordinately Regulated by ERK/MAPK during T Lymphocyte Activation
- (2010) E. L. Carr et al. JOURNAL OF IMMUNOLOGY
- Activation of a Metabolic Gene Regulatory Network Downstream of mTOR Complex 1
- (2010) Katrin Düvel et al. MOLECULAR CELL
- Gluttony, sloth and the metabolic syndrome: a roadmap to lipotoxicity
- (2010) Roger H. Unger et al. TRENDS IN ENDOCRINOLOGY AND METABOLISM
- The Role of Regulatory T Cells in Cancer
- (2010) Tai-You Ha Immune Network
- Functional Anatomy of T Cell Activation and Synapse Formation
- (2009) David R. Fooksman et al. Annual Review of Immunology
- Targeted Therapy for Advanced Prostate Cancer: Inhibition of the PI3K/Akt/mTOR Pathway
- (2009) Todd Morgan et al. CURRENT CANCER DRUG TARGETS
- mTOR: taking cues from the immune microenvironment
- (2009) Greg M. Delgoffe et al. IMMUNOLOGY
- Anergic T Cells Are Metabolically Anergic
- (2009) Y. Zheng et al. JOURNAL OF IMMUNOLOGY
- CD8+ effector T cells contribute to macrophage recruitment and adipose tissue inflammation in obesity
- (2009) Satoshi Nishimura et al. NATURE MEDICINE
- Understanding the Warburg Effect: The Metabolic Requirements of Cell Proliferation
- (2009) M. G. Vander Heiden et al. SCIENCE
- Enhancing Mammalian Target of Rapamycin (mTOR)-Targeted Cancer Therapy by Preventing mTOR/Raptor Inhibition-Initiated, mTOR/Rictor-Independent Akt Activation
- (2008) X. Wang et al. CANCER RESEARCH
- Glucose deprivation inhibits multiple key gene expression events and effector functions in CD8+ T cells
- (2008) Candace M. Cham et al. EUROPEAN JOURNAL OF IMMUNOLOGY
- PI3K pathway alterations in cancer: variations on a theme
- (2008) T L Yuan et al. ONCOGENE
Add your recorded webinar
Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.
Upload NowCreate your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create Now