Neutrophil Functions in Periodontal Homeostasis

Investigating the Association Between Periodontal Disease and Risk of Pancreatic Cancer

(2016) Jeffrey S. Chang et al.   PANCREAS

Update on Prevalence of Periodontitis in Adults in the United States: NHANES 2009 to 2012

(2015) Paul I. Eke et al.   JOURNAL OF PERIODONTOLOGY

Basic biology and role of interleukin-17 in immunity and inflammation

(2015) Camille Zenobia et al.   PERIODONTOLOGY 2000

DEL-1 restrains osteoclastogenesis and inhibits inflammatory bone loss in nonhuman primates

(2015) Jieun Shin et al.   Science Translational Medicine

Novel therapeutic targets in rheumatoid arthritis

(2015) Marije I. Koenders et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Activation of the NLRP3 inflammasome in Porphyromonas gingivalis-accelerated atherosclerosis

(2015) Yohei Yamaguchi et al.   Pathogens and Disease

Regulation of immune responses by neutrophils

(2014) Jing Wang et al.   Annals of the New York Academy of Sciences

Social networking of human neutrophils within the immune system

(2014) P. Scapini et al.   BLOOD

Porphyromonas gingivalis Manipulates Complement and TLR Signaling to Uncouple Bacterial Clearance from Inflammation and Promote Dysbiosis

(2014) Tomoki Maekawa et al.   Cell Host & Microbe

Invasion of Oral and Aortic Tissues by Oral Spirochete Treponema denticola in ApoE−/−Mice Causally Links Periodontal Disease and Atherosclerosis

(2014) Sasanka S. Chukkapalli et al.   INFECTION AND IMMUNITY

Proteases, neutrophils, and periodontitis: the NET effect

(2014) William M. Nauseef   JOURNAL OF CLINICAL INVESTIGATION

Papillon-Lefèvre syndrome patient reveals species-dependent requirements for neutrophil defenses

(2014) Ole E. Sørensen et al.   JOURNAL OF CLINICAL INVESTIGATION

Homeostatic Regulation of Blood Neutrophil Counts

(2014) S. von Vietinghoff et al.   JOURNAL OF IMMUNOLOGY

Genetic and Intervention Studies Implicating Complement C3 as a Major Target for the Treatment of Periodontitis

(2014) T. Maekawa et al.   JOURNAL OF IMMUNOLOGY

Neutrophil homeostasis and inflammation: novel paradigms from studying periodontitis

(2014) G. Hajishengallis et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Quantifying oral inflammatory load: oral neutrophil counts in periodontal health and disease

(2014) M. Landzberg et al.   JOURNAL OF PERIODONTAL RESEARCH

The inflammophilic character of the periodontitis-associated microbiota

(2014) G. Hajishengallis   Molecular Oral Microbiology

Lack of cathelicidin processing in Papillon-Lefèvre syndrome patients reveals essential role of LL-37 in periodontal homeostasis

(2014) Sigrun Eick et al.   Orphanet Journal of Rare Diseases

Defective Neutrophil Recruitment in Leukocyte Adhesion Deficiency Type I Disease Causes Local IL-17-Driven Inflammatory Bone Loss

(2014) N. M. Moutsopoulos et al.   Science Translational Medicine

Historical and contemporary hypotheses on the development of oral diseases: are we there yet?

(2014) Bob T. Rosier et al.   Frontiers in Cellular and Infection Microbiology

The Multifaceted Functions of Neutrophils

(2013) Tanya N. Mayadas et al.   Annual Review of Pathology-Mechanisms of Disease

Commensal bacteria-dependent select expression of CXCL2 contributes to periodontal tissue homeostasis

(2013) Camille Zenobia et al.   CELLULAR MICROBIOLOGY

Periodontitis

(2013) Philip M. Preshaw et al.   ENDOCRINOLOGY AND METABOLISM CLINICS OF NORTH AMERICA

Breaking bad: Manipulation of the host response byPorphyromonas gingivalis

(2013) George Hajishengallis et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Neutrophil Homeostasis and Periodontal Health in Children and Adults

(2013) E. Hajishengallis et al.   JOURNAL OF DENTAL RESEARCH

Diverse novel functions of neutrophils in immunity, inflammation, and beyond

(2013) Attila Mócsai   JOURNAL OF EXPERIMENTAL MEDICINE

Whatˈs your age again? Determination of human neutrophil half-lives revisited

(2013) Tamar Tak et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Activation of neutrophils by autocrine IL-17A–IL-17RC interactions during fungal infection is regulated by IL-6, IL-23, RORγt and dectin-2

(2013) Patricia R Taylor et al.   NATURE IMMUNOLOGY

Polymicrobial Infection with Major Periodontal Pathogens Induced Periodontal Disease and Aortic Atherosclerosis in Hyperlipidemic ApoEnull Mice

(2013) Mercedes F. Rivera et al.   PLoS One

Oral Neutrophil Transcriptome Changes Result in a Pro-Survival Phenotype in Periodontal Diseases

(2013) Flavia S. Lakschevitz et al.   PLoS One

Potential association between prediabetic conditions and gingival and/or periodontal inflammation

(2013) Oelisoa Mireille Andriankaja et al.   Journal of Diabetes Investigation

Leukocyte adhesion deficiencies

(2012) Suhair Hanna et al.   Annals of the New York Academy of Sciences

Neutrophil Function: From Mechanisms to Disease

(2012) Borko Amulic et al.   Annual Review of Immunology

Lessons from rare maladies

(2012) Estelle S. Harris et al.   CURRENT OPINION IN HEMATOLOGY

Therapeutic potential of targeting IL-17

(2012) Sarah A Jones et al.   NATURE IMMUNOLOGY

The leukocyte integrin antagonist Del-1 inhibits IL-17-mediated inflammatory bone loss

(2012) Mehmet A Eskan et al.   NATURE IMMUNOLOGY

Endogenous modulators of inflammatory cell recruitment

(2012) George Hajishengallis et al.   TRENDS IN IMMUNOLOGY

The Th17 Pathway and Inflammatory Diseases of the Intestines, Lungs, and Skin

(2011) Casey T. Weaver et al.   Annual Review of Pathology-Mechanisms of Disease

IL-23-producing CD68+ macrophage-like cells predominate within an IL-17-polarized infiltrate in chronic periodontitis lesions

(2011) Jean-Pierre Allam et al.   JOURNAL OF CLINICAL PERIODONTOLOGY

How has neutrophil research improved our understanding of periodontal pathogenesis?

(2011) Gabriel Nussbaum et al.   JOURNAL OF CLINICAL PERIODONTOLOGY

Fusobacterium nucleatum GroEL induces risk factors of atherosclerosis in human microvascular endothelial cells and ApoE−/− mice

(2011) H-R. Lee et al.   Molecular Oral Microbiology

Diabetes mellitus and periodontitis: a tale of two common interrelated diseases

(2011) Evanthia Lalla et al.   Nature Reviews Endocrinology

Neutrophils, from Marrow to Microbes

(2010) Niels Borregaard   IMMUNITY

The C5a Receptor Impairs IL-12-Dependent Clearance of Porphyromonas gingivalis and Is Required for Induction of Periodontal Bone Loss

(2010) S. Liang et al.   JOURNAL OF IMMUNOLOGY

Refractory Periodontitis Population Characterized by a Hyperactive Oral Neutrophil Phenotype

(2010) Guy M. Aboodi et al.   JOURNAL OF PERIODONTOLOGY

Periodontitis: a polymicrobial disruption of host homeostasis

(2010) Richard P. Darveau   NATURE REVIEWS MICROBIOLOGY

Comparison of neutrophil functions in aggressive and chronic periodontitis

(2010) Mark I. Ryder   PERIODONTOLOGY 2000

Neutrophil kinetics in health and disease

(2010) Charlotte Summers et al.   TRENDS IN IMMUNOLOGY

Surface RANKL of Toll-like receptor 4-stimulated human neutrophils activates osteoclastic bone resorption

(2009) A. Chakravarti et al.   BLOOD

Evidence for a cross-talk between human neutrophils and Th17 cells

(2009) M. Pelletier et al.   BLOOD

Interleukin-1 and IL-23 Induce Innate IL-17 Production from γδ T Cells, Amplifying Th17 Responses and Autoimmunity

(2009) Caroline E. Sutton et al.   IMMUNITY

IL-17 induces osteoclastogenesis from human monocytes alone in the absence of osteoblasts, which is potently inhibited by anti-TNF-α antibody: A novel mechanism of osteoclastogenesis by IL-17

(2009) Toru Yago et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

TLR2-Dependent Inflammatory Response to Porphyromonas gingivalis Is MyD88 Independent, whereas MyD88 Is Required To Clear Infection

(2009) E. Burns et al.   JOURNAL OF IMMUNOLOGY

Novel aspects in the regulation of the leukocyte adhesion cascade

(2009) Emmanouil Chavakis et al.   THROMBOSIS AND HAEMOSTASIS

Periodontal Manifestation of Leukocyte Adhesion Deficiency Type I

(2008) Reem Dababneh et al.   JOURNAL OF PERIODONTOLOGY

Del-1, an Endogenous Leukocyte-Endothelial Adhesion Inhibitor, Limits Inflammatory Cell Recruitment

(2008) E. Y. Choi et al.   SCIENCE