Membrane-Mediated Oligomerization of G Protein Coupled Receptors and Its Implications for GPCR Function
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Title
Membrane-Mediated Oligomerization of G Protein Coupled Receptors and Its Implications for GPCR Function
Authors
Keywords
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Journal
Frontiers in Physiology
Volume 7, Issue -, Pages -
Publisher
Frontiers Media SA
Online
2016-10-25
DOI
10.3389/fphys.2016.00494
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Note: Only part of the references are listed.- The Molecular Switching Mechanism at the Conserved D(E)RY Motif in Class-A GPCRs
- (2016) Angelica Sandoval et al. BIOPHYSICAL JOURNAL
- The function of the two-pore channel TPC1 depends on dimerization of its carboxy-terminal helix
- (2016) Nina Larisch et al. CELLULAR AND MOLECULAR LIFE SCIENCES
- Interaction of G protein coupled receptors and cholesterol
- (2016) Gerald Gimpl CHEMISTRY AND PHYSICS OF LIPIDS
- Dynamic Cholesterol-Conditioned Dimerization of the G Protein Coupled Chemokine Receptor Type 4
- (2016) Kristyna Pluhackova et al. PLoS Computational Biology
- Membrane omega-3 fatty acids modulate the oligomerisation kinetics of adenosine A2A and dopamine D2 receptors
- (2016) Ramon Guixà-González et al. Scientific Reports
- Molecular dynamics simulations of GPCR–cholesterol interaction: An emerging paradigm
- (2015) Durba Sengupta et al. BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES
- Synaptobrevin Transmembrane Domain Dimerization Studied by Multiscale Molecular Dynamics Simulations
- (2015) Jing Han et al. BIOPHYSICAL JOURNAL
- Disruption of Rhodopsin Dimerization with Synthetic Peptides Targeting an Interaction Interface
- (2015) Beata Jastrzebska et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- High-Throughput Simulations of Dimer and Trimer Assembly of Membrane Proteins. The DAFT Approach
- (2015) Tsjerk A. Wassenaar et al. Journal of Chemical Theory and Computation
- Computational Lipidomics with insane: A Versatile Tool for Generating Custom Membranes for Molecular Simulations
- (2015) Tsjerk A. Wassenaar et al. Journal of Chemical Theory and Computation
- Uncovering the triggers for GPCR activation using solid-state NMR spectroscopy
- (2015) Naoki Kimata et al. JOURNAL OF MAGNETIC RESONANCE
- Spontaneous Adsorption of Coiled-Coil Model Peptides K and E to a Mixed Lipid Bilayer
- (2015) Kristyna Pluhackova et al. JOURNAL OF PHYSICAL CHEMISTRY B
- Biomembranes in atomistic and coarse-grained simulations
- (2015) Kristyna Pluhackova et al. JOURNAL OF PHYSICS-CONDENSED MATTER
- Multi-Component Protein - Protein Docking Based Protocol with External Scoring for Modeling Dimers of G Protein-Coupled Receptors
- (2015) Agnieszka A. Kaczor et al. Molecular Informatics
- Conformational dynamics of a class C G-protein-coupled receptor
- (2015) Reza Vafabakhsh et al. NATURE
- Two disparate ligand-binding sites in the human P2Y1 receptor
- (2015) Dandan Zhang et al. NATURE
- Structural insights into µ-opioid receptor activation
- (2015) Weijiao Huang et al. NATURE
- Methodological advances: the unsung heroes of the GPCR structural revolution
- (2015) Eshan Ghosh et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Structures for G-Protein-Coupled Receptor Tetramers in Complex with G Proteins
- (2015) Arnau Cordomí et al. TRENDS IN BIOCHEMICAL SCIENCES
- Preferred Supramolecular Organization and Dimer Interfaces of Opioid Receptors from Simulated Self-Association
- (2015) Davide Provasi et al. PLoS Computational Biology
- What can we learn from molecular dynamics simulations for GPCR drug design?
- (2015) Christofer S. Tautermann et al. Computational and Structural Biotechnology Journal
- Dimerization of the EphA1 Receptor Tyrosine Kinase Transmembrane Domain: Insights into the Mechanism of Receptor Activation
- (2014) Matthieu Chavent et al. BIOCHEMISTRY
- Cholesterol Modulates the Dimer Interface of the β2-Adrenergic Receptor via Cholesterol Occupancy Sites
- (2014) Xavier Prasanna et al. BIOPHYSICAL JOURNAL
- Cholesterol, sphingolipids, and glycolipids: What do we know about their role in raft-like membranes?
- (2014) Tomasz Róg et al. CHEMISTRY AND PHYSICS OF LIPIDS
- Computational Approaches for Modeling GPCR Dimerization
- (2014) Xuan-Yu Meng et al. CURRENT PHARMACEUTICAL BIOTECHNOLOGY
- A Functional Selectivity Mechanism at the Serotonin-2A GPCR Involves Ligand-Dependent Conformations of Intracellular Loop 2
- (2014) Jose Manuel Perez-Aguilar et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Structure of the human P2Y12 receptor in complex with an antithrombotic drug
- (2014) Kaihua Zhang et al. NATURE
- Structure of a Class C GPCR Metabotropic Glutamate Receptor 1 Bound to an Allosteric Modulator
- (2014) H. Wu et al. SCIENCE
- Stereospecific requirement of cholesterol in the function of the serotonin1A receptor
- (2013) Md. Jafurulla et al. BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES
- Perspective on the Martini model
- (2013) Siewert J. Marrink et al. CHEMICAL SOCIETY REVIEWS
- Molecular Modeling and Simulation of Membrane Lipid-Mediated Effects on GPCRs
- (2013) S.K. Sadiq et al. CURRENT MEDICINAL CHEMISTRY
- Single-molecule imaging revealed dynamic GPCR dimerization
- (2013) Rinshi S Kasai et al. CURRENT OPINION IN CELL BIOLOGY
- Bridging Molecular Docking to Membrane Molecular Dynamics To Investigate GPCR–Ligand Recognition: The Human A2A Adenosine Receptor as a Key Study
- (2013) Davide Sabbadin et al. Journal of Chemical Information and Modeling
- Toward Optimized Potential Functions for Protein–Protein Interactions in Aqueous Solutions: Osmotic Second Virial Coefficient Calculations Using the MARTINI Coarse-Grained Force Field
- (2013) Austin C. Stark et al. Journal of Chemical Theory and Computation
- Fluorescence resonance energy transfer microscopy as demonstrated by measuring the activation of the serine/threonine kinase Akt
- (2013) Joshua A Broussard et al. Nature Protocols
- Structural Features for Functional Selectivity at Serotonin Receptors
- (2013) D. Wacker et al. SCIENCE
- Membrane Driven Spatial Organization of GPCRs
- (2013) Sayan Mondal et al. Scientific Reports
- Receptor oligomerization: from early evidence to current understanding in class B GPCRs
- (2013) Stephanie Y. L. Ng et al. Frontiers in Endocrinology
- Regulation of G protein-coupled receptors by palmitoylation and cholesterol
- (2012) Alan D Goddard et al. BMC BIOLOGY
- Palmitoylation and membrane cholesterol stabilize μ-opioid receptor homodimerization and G protein coupling
- (2012) Hui Zheng et al. BMC CELL BIOLOGY
- Improved Parameters for the Martini Coarse-Grained Protein Force Field
- (2012) Djurre H. de Jong et al. Journal of Chemical Theory and Computation
- Cholesterol level influences opioid signaling in cell models and analgesia in mice and humans
- (2012) Hui Zheng et al. JOURNAL OF LIPID RESEARCH
- Identification of Cholesterol Binding Sites in the Serotonin1A Receptor
- (2012) Durba Sengupta et al. JOURNAL OF PHYSICAL CHEMISTRY B
- Crystal structure of the µ-opioid receptor bound to a morphinan antagonist
- (2012) Aashish Manglik et al. NATURE
- Cholesterol increases kinetic, energetic, and mechanical stability of the human 2-adrenergic receptor
- (2012) M. Zocher et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Single-molecule analysis of fluorescently labeled G-protein-coupled receptors reveals complexes with distinct dynamics and organization
- (2012) D. Calebiro et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Structural Basis for Allosteric Regulation of GPCRs by Sodium Ions
- (2012) W. Liu et al. SCIENCE
- Biased Signaling Pathways in 2-Adrenergic Receptor Characterized by 19F-NMR
- (2012) J. J. Liu et al. SCIENCE
- BRET and Time-resolved FRET strategy to study GPCR oligomerization: from cell lines toward native tissues
- (2012) Martin Cottet et al. Frontiers in Endocrinology
- Cholesterol-induced conformational changes in the oxytocin receptor
- (2011) Sabine Muth et al. BIOCHEMICAL JOURNAL
- The role of membrane thickness in charged protein–lipid interactions
- (2011) Libo B. Li et al. BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES
- Quantitative Modeling of Membrane Deformations by Multihelical Membrane Proteins: Application to G-Protein Coupled Receptors
- (2011) Sayan Mondal et al. BIOPHYSICAL JOURNAL
- Uncovering the intimate relationship between lipids, cholesterol and GPCR activation
- (2011) Joanne Oates et al. CURRENT OPINION IN STRUCTURAL BIOLOGY
- Oligomerization of the Serotonin1AReceptor in Live Cells: A Time-Resolved Fluorescence Anisotropy Approach
- (2011) Yamuna Devi Paila et al. JOURNAL OF PHYSICAL CHEMISTRY B
- Cholesterol Regulates -Opioid Receptor-Induced -Arrestin 2 Translocation to Membrane Lipid Rafts
- (2011) Y. Qiu et al. MOLECULAR PHARMACOLOGY
- Dimers and beyond: The functional puzzles of class C GPCRs
- (2011) Julie Kniazeff et al. PHARMACOLOGY & THERAPEUTICS
- Diversity and modularity of G protein-coupled receptor structures
- (2011) Vsevolod Katritch et al. TRENDS IN PHARMACOLOGICAL SCIENCES
- Disclosure of cholesterol recognition motifs in transmembrane domains of the human nicotinic acetylcholine receptor
- (2011) Carlos J. Baier et al. Scientific Reports
- Identification of cholesterol recognition amino acid consensus (CRAC) motif in G-protein coupled receptors
- (2010) Md. Jafurulla et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Self-Association of Models of Transmembrane Domains of ErbB Receptors in a Lipid Bilayer
- (2010) Anupam Prakash et al. BIOPHYSICAL JOURNAL
- Impact of the DRY Motif and the Missing "Ionic Lock" on Constitutive Activity and G-Protein Coupling of the Human Histamine H4 Receptor
- (2010) E. H. Schneider et al. JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS
- Role of Antibodies in Developing Drugs That Target G-Protein-Coupled Receptor Dimers
- (2010) Chris Hipser et al. MOUNT SINAI JOURNAL OF MEDICINE
- Structures of the CXCR4 Chemokine GPCR with Small-Molecule and Cyclic Peptide Antagonists
- (2010) B. Wu et al. SCIENCE
- Recent advances in bioluminescence resonance energy transfer technologies to study GPCR heteromerization
- (2009) Mohammed A Ayoub et al. CURRENT OPINION IN PHARMACOLOGY
- G-protein-coupled receptors, cholesterol and palmitoylation: facts about fats
- (2009) Bice Chini et al. JOURNAL OF MOLECULAR ENDOCRINOLOGY
- The structure and function of G-protein-coupled receptors
- (2009) Daniel M. Rosenbaum et al. NATURE
- Lipid Raft-Mediated Regulation of G-Protein Coupled Receptor Signaling by Ligands which Influence Receptor Dimerization: A Computational Study
- (2009) Mohammad Fallahi-Sichani et al. PLoS One
- Effect of cholesterol on the structure of a phospholipid bilayer
- (2009) F. de Meyer et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- A Role for a Specific Cholesterol Interaction in Stabilizing the Apo Configuration of the Human A 2A Adenosine Receptor
- (2009) Edward Lyman et al. STRUCTURE
- Stimulation- and palmitoylation-dependent changes in oligomeric conformation of serotonin 5-HT1A receptorsi
- (2008) Fritz Kobe et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH
- The A2A-adenosine receptor: a GPCR with unique features?
- (2008) J Zezula et al. BRITISH JOURNAL OF PHARMACOLOGY
- Ligand sensitivity in dimeric associations of the serotonin 5HT2c receptor
- (2008) Filippo Mancia et al. EMBO REPORTS
- Cholesterol-dependent Separation of the β2-Adrenergic Receptor from Its Partners Determines Signaling Efficacy
- (2008) Stéphanie M. Pontier et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- The MARTINI Coarse-Grained Force Field: Extension to Proteins
- (2008) Luca Monticelli et al. Journal of Chemical Theory and Computation
- Dimerization and oligomerization of G-protein-coupled receptors: debated structures with established and emerging functions
- (2008) László Szidonya et al. JOURNAL OF ENDOCRINOLOGY
- Molecular recognition of parathyroid hormone by its G protein-coupled receptor
- (2008) Augen A. Pioszak et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Insights from biophysical studies on the role of polyunsaturated fatty acids for function of G-protein coupled membrane receptors
- (2008) Klaus Gawrisch et al. PROSTAGLANDINS LEUKOTRIENES AND ESSENTIAL FATTY ACIDS
- A Specific Cholesterol Binding Site Is Established by the 2.8 Å Structure of the Human β2-Adrenergic Receptor
- (2008) Michael A. Hanson et al. STRUCTURE
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