Disruption of Rhodopsin Dimerization with Synthetic Peptides Targeting an Interaction Interface

Analysis of Human Dopamine D3Receptor Quaternary Structure

(2015) Sara Marsango et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Higher-Order Architecture of Rhodopsin in Intact Photoreceptors and Its Implication for Phototransduction Kinetics

(2015) Monika Gunkel et al.   STRUCTURE

The GPCR heterotetramer: challenging classical pharmacology

(2015) Sergi Ferré   TRENDS IN PHARMACOLOGICAL SCIENCES

G-Protein-Coupled Receptors Oligomerization: Emerging Signaling Units and New Opportunities for Drug Design

(2014) Merce Tena-Campos et al.   CURRENT PROTEIN & PEPTIDE SCIENCE

Transmembrane peptides as unique tools to demonstrate the in vivo action of a cross-class GPCR heterocomplex

(2014) Leo T. O. Lee et al.   FASEB JOURNAL

Inherent Instability of the Retinitis Pigmentosa P23H Mutant Opsin

(2014) Yuanyuan Chen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

CrossTalk opposing view: Weighing the evidence for class A GPCR dimers, the jury is still out

(2014) Nevin A. Lambert et al.   JOURNAL OF PHYSIOLOGY-LONDON

Time-Resolved Fluorescence Spectroscopy Measures Clustering and Mobility of a G Protein-Coupled Receptor Opsin in Live Cell Membranes

(2014) William D. Comar et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Major ligand-induced rearrangement of the heptahelical domain interface in a GPCR dimer

(2014) Li Xue et al.   Nature Chemical Biology

GPCR: G protein complexes—the fundamental signaling assembly

(2013) Beata Jastrzebska   AMINO ACIDS

Asymmetry of the rhodopsin dimer in complex with transducin

(2013) Beata Jastrzebska et al.   FASEB JOURNAL

The rhodopsin-transducin complex houses two distinct rhodopsin molecules

(2013) Beata Jastrzebska et al.   JOURNAL OF STRUCTURAL BIOLOGY

Crystal structure of oligomeric β1-adrenergic G protein–coupled receptors in ligand-free basal state

(2013) Jianyun Huang et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Rhodopsin Forms a Dimer with Cytoplasmic Helix 8 Contacts in Native Membranes

(2012) Adam M. Knepp et al.   BIOCHEMISTRY

Oligomerization of G Protein-Coupled Receptors: Computational Methods

(2012) J. Selent et al.   CURRENT MEDICINAL CHEMISTRY

Structural Determinants of the Supramolecular Organization of G Protein-Coupled Receptors in Bilayers

(2012) Xavier Periole et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Structure of the human κ-opioid receptor in complex with JDTic

(2012) Huixian Wu et al.   NATURE

Crystal structure of the µ-opioid receptor bound to a morphinan antagonist

(2012) Aashish Manglik et al.   NATURE

Validation of an Optical Microplate Label-Free Platform in the Screening of Chemical Libraries for Direct Binding to a Nuclear Receptor

(2011) Laura Vela et al.   ASSAY AND DRUG DEVELOPMENT TECHNOLOGIES

A dynamic scaffolding mechanism for rhodopsin and transducin interaction in vertebrate vision

(2011) Daniele Dell'Orco et al.   BIOCHEMICAL JOURNAL

The Bilayer Enhances Rhodopsin Kinetic Stability in Bovine Rod Outer Segment Disk Membranes

(2011) Scott C. Corley et al.   BIOPHYSICAL JOURNAL

Structural Basis of M3Muscarinic Receptor Dimer/Oligomer Formation

(2011) Sara M. McMillin et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Rhodopsin–transducin heteropentamer: Three-dimensional structure and biochemical characterization

(2011) Beata Jastrzebska et al.   JOURNAL OF STRUCTURAL BIOLOGY

Crystal structure of metarhodopsin II

(2011) Hui-Woog Choe et al.   NATURE

The Significance of G Protein-Coupled Receptor Crystallography for Drug Discovery

(2011) J. A. Salon et al.   PHARMACOLOGICAL REVIEWS

Asymmetry of GPCR oligomers supports their functional relevance

(2011) Pascal Maurice et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Complexes between photoactivated rhodopsin and transducin: progress and questions

(2010) Beata Jastrzebska et al.   BIOCHEMICAL JOURNAL

Time-resolved FRET between GPCR ligands reveals oligomers in native tissues

(2010) Laura Albizu et al.   Nature Chemical Biology

Structures of the CXCR4 Chemokine GPCR with Small-Molecule and Cyclic Peptide Antagonists

(2010) B. Wu et al.   SCIENCE

Nanoscale organization of β 2 -adrenergic receptor-Venus fusion protein domains on the surface of mammalian cells

(2009) Dusan Vobornik et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Functional reconstitution of the human serotonin receptor 5-HT6 using synthetic transmembrane peptides

(2009) Won-Kyu Lee et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

G protein-coupled receptor hetero-dimerization: contribution to pharmacology and function

(2009) Graeme Milligan   BRITISH JOURNAL OF PHARMACOLOGY

Bioinformatics and molecular modelling approaches to GPCR oligomerization

(2009) Lisa M Simpson et al.   CURRENT OPINION IN PHARMACOLOGY

The apparent cooperativity of some GPCRs does not necessarily imply dimerization

(2009) Marc Chabre et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Different Properties of the Native and Reconstituted Heterotrimeric G Protein Transducin†

(2008) Anna Goc et al.   BIOCHEMISTRY

Ligand sensitivity in dimeric associations of the serotonin 5HT2c receptor

(2008) Filippo Mancia et al.   EMBO REPORTS

Vertebrate Membrane Proteins: Structure, Function, and Insights from Biophysical Approaches

(2008) D. J. Muller et al.   PHARMACOLOGICAL REVIEWS

A day in the life of a G protein-coupled receptor: the contribution to function of G protein-coupled receptor dimerization

(2007) G Milligan   BRITISH JOURNAL OF PHARMACOLOGY