San-Huang-Xie-Xin-Tang Constituents Exert Drug-Drug Interaction of Mutual Reinforcement at Both Pharmacodynamics and Pharmacokinetic Level: A Review

Coptisine from Coptis chinensis inhibits production of inflammatory mediators in lipopolysaccharide-stimulated RAW 264.7 murine macrophage cells

(2016) Jiasi Wu et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Nitro-oleic acid modulates classical and regulatory activation of macrophages and their involvement in pro-fibrotic responses

(2016) Gabriela Ambrozova et al.   FREE RADICAL BIOLOGY AND MEDICINE

Baicalein alleviates doxorubicin-induced cardiotoxicity via suppression of myocardial oxidative stress and apoptosis in mice

(2016) Bidya Dhar Sahu et al.   LIFE SCIENCES

Suitability of the in vitro Caco-2 assay to predict the oral absorption of aromatic amine hair dyes

(2016) Cindy Obringer et al.   TOXICOLOGY IN VITRO

Untargeted Metabolomics Reveals Dose-Response Characteristics for Effect of Rhubarb in a Rat Model of Cholestasis

(2016) Cong-En Zhang et al.   Frontiers in Pharmacology

Clinical Strategy for Optimal Traditional Chinese Medicine (TCM) Herbal Dose Selection in Disease Therapeutics: Expert Consensus on Classic TCM Herbal Formula Dose Conversion

(2015) Lin-Hua Zha et al.   AMERICAN JOURNAL OF CHINESE MEDICINE

Resolution of Inflammation by Resolvin D1 Is Essential for Peroxisome Proliferator–activated Receptor-γ–mediated Analgesia during Postincisional Pain Development in Type 2 Diabetes

(2015) Takayuki Saito et al.   ANESTHESIOLOGY

Small molecule inhibits activity of scavenger receptor A: Lead identification and preliminary studies

(2015) Yunyun Yuan et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Large dose means significant effect – dose and effect relationship of Chi-Dan-Tui-Huang decoction on alpha-naphthylisothiocyanate-induced cholestatic hepatitis in rats

(2015) Yanling Zhao et al.   BMC Complementary and Alternative Medicine

NDP-α-MSH attenuates heart and liver responses to myocardial reperfusion via the vagus nerve and JAK/ERK/STAT signaling

(2015) Alessandra Ottani et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Comparative pharmacokinetics of arctigenin in normal and type 2 diabetic rats after oral and intravenous administration

(2015) Xiao-yan Zeng et al.   FITOTERAPIA

Toll-like receptor 4 is involved in a protective effect of rhein on immunoglobulin A nephropathy

(2015) Qingxian Zhu et al.   INDIAN JOURNAL OF PHARMACOLOGY

Baicalin Inhibits Lipopolysaccharide-Induced Inflammation Through Signaling NF-κB Pathway in HBE16 Airway Epithelial Cells

(2015) Shou-jin Dong et al.   INFLAMMATION

STAT1 and IRF8 in Vascular Inflammation and Cardiovascular Disease: Diagnostic and Therapeutic Potential

(2015) Stefan Chmielewski et al.   INTERNATIONAL REVIEWS OF IMMUNOLOGY

Probing the Solution Structure of IκB Kinase (IKK) Subunit γ and Its Interaction with Kaposi Sarcoma-associated Herpes Virus Flice-interacting Protein and IKK Subunit β by EPR Spectroscopy

(2015) Claire Bagnéris et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A herbal formula comprising Rosae Multiflorae Fructus and Lonicerae Japonicae Flos inhibits the production of inflammatory mediators and the IRAK-1/TAK1 and TBK1/IRF3 pathways in RAW 264.7 and THP-1 cells

(2015) Brian Chi Yan Cheng et al.   JOURNAL OF ETHNOPHARMACOLOGY

Adipose-Derived Mesenchymal Stem Cells Prevent Systemic Bone Loss in Collagen-Induced Arthritis

(2015) M. G. Garimella et al.   JOURNAL OF IMMUNOLOGY

Baicalein attenuates renal fibrosis by inhibiting inflammation via down-regulating NF-κB and MAPK signal pathways

(2015) Wei Wang et al.   JOURNAL OF MOLECULAR HISTOLOGY

Effect of piperine on the bioavailability and pharmacokinetics of emodin in rats

(2015) Xin Di et al.   JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS

Rhein inhibits lipopolysaccharide-induced intestinal injury during sepsis by blocking the toll-like receptor 4 nuclear factor-κB pathway

(2015) KE ZHANG et al.   Molecular Medicine Reports

Selenofuranoside Ameliorates Memory Loss in Alzheimer-Like Sporadic Dementia: AChE Activity, Oxidative Stress, and Inflammation Involvement

(2015) Cristiano Chiapinotto Spiazzi et al.   Oxidative Medicine and Cellular Longevity

Role of organic cation transporters (OCTs) in the brain

(2015) Thomas Couroussé et al.   PHARMACOLOGY & THERAPEUTICS

Multiple ABC Transporters Efflux Baicalin

(2015) Bernadett Kalapos-Kovács et al.   PHYTOTHERAPY RESEARCH

Distinct single-cell signaling characteristics are conferred by the MyD88 and TRIF pathways during TLR4 activation

(2015) Zhang Cheng et al.   Science Signaling

Emodin Suppresses Maintenance of Stemness by Augmenting Proteosomal Degradation of Epidermal Growth Factor Receptor/Epidermal Growth Factor Receptor Variant III in Glioma Stem Cells

(2015) Jeongyub Kim et al.   STEM CELLS AND DEVELOPMENT

LKB1/AMPK inhibits TGF-β1 production and the TGF-β signaling pathway in breast cancer cells

(2015) Nian-Shuang Li et al.   TUMOR BIOLOGY

TRIB3-P62 interaction, diabetes and autophagy

(2015) Fang Hua et al.   Oncotarget

Genistein and Glyceollin Effects on ABCC2 (MRP2) and ABCG2 (BCRP) in Caco-2 Cells

(2015) Chandler Schexnayder et al.   International Journal of Environmental Research and Public Health

Immunoregulation of Bone Marrow-Derived Mesenchymal Stem Cells on the Chronic Cigarette Smoking-Induced Lung Inflammation in Rats

(2015) Xiaoyan Li et al.   Biomed Research International

Distinct single-cell signaling characteristics are conferred by the MyD88 and TRIF pathways during TLR4 activation

(2015) Zhang Cheng et al.   Science Signaling

Combination of Active Components of Xiexin Decoction Ameliorates Renal Fibrosis Through the Inhibition of NF-κB and TGF-β1/Smad Pathways in db/db Diabetic Mice

(2015) Jia-Sheng Wu et al.   PLoS One

Association of MTOR and AKT Gene Polymorphisms with Susceptibility and Survival of Gastric Cancer

(2015) Ying Piao et al.   PLoS One

Baicalein, a Bioflavonoid, Prevents Cisplatin-Induced Acute Kidney Injury by Up-Regulating Antioxidant Defenses and Down-Regulating the MAPKs and NF-κB Pathways

(2015) Bidya Dhar Sahu et al.   PLoS One

Rhein prevents endotoxin-induced acute kidney injury by inhibiting NF-κB activities

(2015) Chen Yu et al.   Scientific Reports

Baicalein Attenuates Angiotensin II-Induced Cardiac Remodeling via Inhibition of AKT/mTOR, ERK1/2, NF-κB, and Calcineurin Signaling Pathways in Mice

(2014) Ai-Wu Wang et al.   AMERICAN JOURNAL OF HYPERTENSION

Effect of Coptidis Rhizoma extracts in a water-based solution on insulin resistance in 3T3-L1 adipocytes

(2014) Yi YUAN et al.   BIOMEDICAL RESEARCH-TOKYO

Emodin Isolated from Polygoni cuspidati Radix Inhibits TNF-α and IL-6 Release by Blockading NF-κB and MAP Kinase Pathways in Mast Cells Stimulated with PMA Plus A23187

(2014) Yue Lu et al.   Biomolecules & Therapeutics

Revisiting PPARγ as a target for the treatment of metabolic disorders

(2014) Sun-Sil Choi et al.   BMB Reports

Protective effect of emodin against airway inflammation in the ovalbumin-induced mouse model

(2014) Tan Wang et al.   Chinese Journal of Integrative Medicine

Choline acetyltransferase and organic cation transporters are responsible for synthesis and propionate-induced release of acetylcholine in colon epithelium

(2014) Sandra Bader et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Taurine ameliorates neuropathy via regulating NF-κB and Nrf2/HO-1 signaling cascades in diabetic rats

(2014) Can Ali Agca et al.   FOOD AND CHEMICAL TOXICOLOGY

Rhein exerts pro- and anti-inflammatory actions by targeting IKKβ inhibition in LPS-activated macrophages

(2014) Yuan Gao et al.   FREE RADICAL BIOLOGY AND MEDICINE

Berberine Ameliorates Collagen-Induced Arthritis in Rats Associated with Anti-inflammatory and Anti-angiogenic Effects

(2014) Zhigang Wang et al.   INFLAMMATION

Emodin inhibits LPS-induced inflammatory response by activating PPAR-γ in mouse mammary epithelial cells

(2014) Zhengtao Yang et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Emodin Ameliorates LPS-Induced Acute Lung Injury, Involving the Inactivation of NF-κB in Mice

(2014) Min Xiao et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Preparation, pharmacokinetics and biodistribution of baicalin-loaded liposomes

(2014) Ling Zhao et al.   International Journal of Nanomedicine

Nuclear Factor-κB-inducing Kinase (NIK) Contains an Amino-terminal Inhibitor of Apoptosis (IAP)-binding Motif (IBM) That Potentiates NIK Degradation by Cellular IAP1 (c-IAP1)

(2014) Sunhee Lee et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Sweet taste receptor expression in ruminant intestine and its activation by artificial sweeteners to regulate glucose absorption

(2014) A.W. Moran et al.   JOURNAL OF DAIRY SCIENCE

Integrated pharmacokinetics of five protoberberine-type alkaloids in normal and insomnic rats after single and multiple oral administration of Jiao-Tai-Wan

(2014) Wei He et al.   JOURNAL OF ETHNOPHARMACOLOGY

Effects of San-Huang-Xie-Xin-tang, a traditional Chinese prescription for clearing away heat and toxin, on the pacemaker activities of interstitial cells of Cajal from the murine small intestine

(2014) Byung Joo Kim et al.   JOURNAL OF ETHNOPHARMACOLOGY

Baicalein, an active component of Scutellaria baicalensis, protects against lipopolysaccharide-induced acute lung injury in rats

(2014) Chen-Liang Tsai et al.   JOURNAL OF ETHNOPHARMACOLOGY

Casticin inhibits COX-2 and iNOS expression via suppression of NF-κB and MAPK signaling in lipopolysaccharide-stimulated mouse macrophages

(2014) Chian-Jiun Liou et al.   JOURNAL OF ETHNOPHARMACOLOGY

Aloe-emodin from rhubarb (Rheum rhabarbarum) inhibits lipopolysaccharide-induced inflammatory responses in RAW264.7 macrophages

(2014) Boyang Hu et al.   JOURNAL OF ETHNOPHARMACOLOGY

Alpha-lipoic acid improves high-fat diet-induced hepatic steatosis by modulating the transcription factors SREBP-1, FoxO1 and Nrf2 via the SIRT1/LKB1/AMPK pathway

(2014) Yi Yang et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Berberine derivatives reduce atherosclerotic plaque size and vulnerability in apoE−/− mice

(2014) Junwen Chen et al.   Journal of Translational Medicine

Berberine Induces Senescence of Human Glioblastoma Cells by Downregulating the EGFR-MEK-ERK Signaling Pathway

(2014) Q. Liu et al.   MOLECULAR CANCER THERAPEUTICS

Berberine regulates AMP-activated protein kinase signaling pathways and inhibits colon tumorigenesis in mice

(2014) Weidong Li et al.   MOLECULAR CARCINOGENESIS

Baicalein ameliorates cognitive deficits in epilepsy-like tremor rat

(2014) Xiaoyuan Mao et al.   NEUROLOGICAL SCIENCES

Effects of the antioxidant baicalein on the pharmacokinetics of nimodipine in rats: a possible role of P-glycoprotein and CYP3A4 inhibition by baicalein

(2014) Young-Ah Cho et al.   Pharmacological Reports

Approaches to Improve the Oral Bioavailability and Effects of Novel Anticancer Drugs Berberine and Betulinic Acid

(2014) Chandraiah Godugu et al.   PLoS One

Ginsenoside Metabolite Compound K Promotes Recovery of Dextran Sulfate Sodium-Induced Colitis and Inhibits Inflammatory Responses by Suppressing NF-κB Activation

(2014) Juan Li et al.   PLoS One

Berberine Protects against Neuronal Damage via Suppression of Glia-Mediated Inflammation in Traumatic Brain Injury

(2014) Chien-Cheng Chen et al.   PLoS One

Interaction of Rhubarb and Methotrexate in Rats: In Vivo and Ex Vivo Approaches

(2013) Chi-Sheng Shia et al.   AMERICAN JOURNAL OF CHINESE MEDICINE

Rhein Inhibits the Expression of Vascular Cell Adhesion Molecule 1 in Human Umbilical Vein Endothelial Cells with or without Lipopolysaccharide Stimulation

(2013) Gang Hu et al.   AMERICAN JOURNAL OF CHINESE MEDICINE

The Crosstalk Between Nrf2 and AMPK Signal Pathways Is Important for the Anti-Inflammatory Effect of Berberine in LPS-Stimulated Macrophages and Endotoxin-Shocked Mice

(2013) Chunfen Mo et al.   ANTIOXIDANTS & REDOX SIGNALING

Inhibition of 12/15 lipoxygenase by baicalein reduces myocardial ischemia/reperfusion injury via modulation of multiple signaling pathways

(2013) Lina Song et al.   APOPTOSIS

Rhein lysinate inhibits monocyte adhesion to human umbilical vein endothelial cells by blocking p38 signaling pathway

(2013) Yajun Lin et al.   ARCHIVES OF PHARMACAL RESEARCH

UPLC-ESI/MS determination of 17 active constituents in two categorized formulas of traditional Chinese medicine, Sanhuang Xiexin Tang and Fuzi Xiexin Tang: application in comparing the differences in decoctions and macerations

(2013) Qian Zhang et al.   BIOMEDICAL CHROMATOGRAPHY

Emodin inhibits growth and induces apoptosis in an orthotopic hepatocellular carcinoma model by blocking activation of STAT3

(2013) Aruljothi Subramaniam et al.   BRITISH JOURNAL OF PHARMACOLOGY

Pharmacokinetic–pharmacodynamic evaluation of the major component astragaloside IV on the immunomodulatory effects of Yu-ping-feng prescription

(2013) Jue Song et al.   EUROPEAN JOURNAL OF DRUG METABOLISM AND PHARMACOKINETICS

Emodin ameliorates lipopolysaccharide-induced mastitis in mice by inhibiting activation of NF-κB and MAPKs signal pathways

(2013) Depeng Li et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Potential role of ATP-binding cassette transporters in the intestinal transport of rhein

(2013) Ling Ye et al.   FOOD AND CHEMICAL TOXICOLOGY

Berberine exerts nephroprotective effect against cisplatin-induced kidney damage through inhibition of oxidative/nitrosative stress, inflammation, autophagy and apoptosis

(2013) Robert Domitrović et al.   FOOD AND CHEMICAL TOXICOLOGY

Effect of Emodin on Endoplasmic Reticulum Stress in Rats with Severe Acute Pancreatitis

(2013) Li Wu et al.   INFLAMMATION

Anti-inflammatory Activity of Baicalein in LPS-Stimulated RAW264.7 Macrophages via Estrogen Receptor and NF-κB-Dependent Pathways

(2013) Guan-Wei Fan et al.   INFLAMMATION

Berberine Attenuates Cigarette Smoke-Induced Acute Lung Inflammation

(2013) Kexiong Lin et al.   INFLAMMATION

Baicalein reduces lipopolysaccharide-induced inflammation via suppressing JAK/STATs activation and ROS production

(2013) Zhilin Qi et al.   INFLAMMATION RESEARCH

Influence of borneol and muscone on geniposide transport through MDCK and MDCK-MDR1 cells as blood–brain barrier in vitro model

(2013) Zhen-Zhen Chen et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Emodin Improves Lipopolysaccharide-Induced Microcirculatory Disturbance in Rat Mesentery

(2013) Ang Li et al.   MICROCIRCULATION

Berberine ameliorates experimental diabetes-induced renal inflammation and fibronectin by inhibiting the activation of RhoA/ROCK signaling

(2013) Xi Xie et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Differences in Pharmacokinetics and Anti-inflammatory Effects between Decoction and Maceration of Sanhuang Xiexin Tang in Rats and Mice

(2013) Qian Zhang et al.   PLANTA MEDICA

Berberine Ameliorates Chronic Kidney Injury Caused by Atherosclerotic Renovascular Disease through the Suppression of NFκB Signaling Pathway in Rats

(2013) Xin Wan et al.   PLoS One

Inhibitory Effect of Baicalin on iNOS and NO Expression in Intestinal Mucosa of Rats with Acute Endotoxemia

(2013) Aiwen Feng et al.   PLoS One

Emodin suppresses inflammatory responses and joint destruction in collagen-induced arthritic mice

(2013) Jin-Ki Hwang et al.   RHEUMATOLOGY

Drug-induced activation of the nervous control of inflammation: A novel possibility for the treatment of hypoxic damage

(2012) Alfio Bertolini   EUROPEAN JOURNAL OF PHARMACOLOGY

In vitro intestinal transport of oligomeric procyanidins (DP 2 to 4) across monolayers of Caco-2 cells

(2012) Stefanie Zumdick et al.   FITOTERAPIA

Identification of novel dietary phytochemicals inhibiting the efflux transporter breast cancer resistance protein (BCRP/ABCG2)

(2012) Kee W. Tan et al.   FOOD CHEMISTRY

Baicalin attenuates proinflammatory cytokine production in oxygen–glucose deprived challenged rat microglial cells by inhibiting TLR4 signaling pathway

(2012) Jincai Hou et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Yohimbine Enhances Protection of Berberine against LPS-Induced Mouse Lethality through Multiple Mechanisms

(2012) Hui Li et al.   PLoS One

Anti-Inflammatory Activity of a Novel Family of Aryl Ureas Compounds in an Endotoxin-Induced Airway Epithelial Cell Injury Model

(2012) Nuria E. Cabrera-Benitez et al.   PLoS One

CaMKKβ Is Involved in AMP-Activated Protein Kinase Activation by Baicalin in LKB1 Deficient Cell Lines

(2012) Ying Ma et al.   PLoS One

Coupling of UDP-glucuronosyltransferases and multidrug resistance-associated proteins is responsible for the intestinal disposition and poor bioavailability of emodin

(2012) Wei Liu et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Berberine protects against lipopolysaccharide-induced intestinal injury in mice via alpha 2 adrenoceptor-independent mechanisms

(2011) Hong-mei Li et al.   ACTA PHARMACOLOGICA SINICA

PPARγ activation by baicalin suppresses NF-κB-mediated inflammation in aged rat kidney

(2011) Hyun Ae Lim et al.   BIOGERONTOLOGY

Inhibition of the signalling kinase JAK3 alleviates inflammation in monoarthritic rats

(2011) Byung-Hak Kim et al.   BRITISH JOURNAL OF PHARMACOLOGY

Rhein inhibits angiogenesis and the viability of hormone-dependent and -independent cancer cells under normoxic or hypoxic conditions in vitro

(2011) Vivian E. Fernand et al.   CHEMICO-BIOLOGICAL INTERACTIONS

Antiangiogenic activity of berberine is mediated through the downregulation of hypoxia-inducible factor-1, VEGF, and proinflammatory mediators

(2011) T.P. Hamsa et al.   DRUG AND CHEMICAL TOXICOLOGY

Effects of silymarin and formulation on the oral bioavailability of paclitaxel in rats

(2011) Joon Hee Park et al.   EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES

ER Stress, P66shc, and P-Akt/Akt Mediate Adjuvant-Induced Inflammation, Which Is Blunted by Argirein, a Supermolecule and Rhein in Rats

(2011) Xiao-Dong Cong et al.   INFLAMMATION

Nanoscale hepatoprotective herbal decoction attenuates hepatic stellate cell activity and chloroform-induced liver damage in mice

(2011) Sherry Huang   International Journal of Nanomedicine

Baicalein, an active component of Scutellaria baicalensis Georgi, improves cardiac contractile function in endotoxaemic rats via induction of heme oxygenase-1 and suppression of inflammatory responses

(2011) Yen-Mei Lee et al.   JOURNAL OF ETHNOPHARMACOLOGY

Combined Phytochemistry and Chemotaxis Assays for Identification and Mechanistic Analysis of Anti-Inflammatory Phytochemicals in Fallopia japonica

(2011) Ming-Yi Shen et al.   PLoS One

Intestinal absorption mechanisms of berberine, palmatine, jateorhizine, and coptisine: involvement of P-glycoprotein

(2011) Xinfeng Zhang et al.   XENOBIOTICA

Scope of claim coverage in patents of fufang Chinese herbal drugs: Substitution of ingredients

(2011) Xinsheng Wang et al.   Chinese Medicine

Emodin suppresses lipopolysaccharide-induced pro-inflammatory responses and NF-κB activation by disrupting lipid rafts in CD14-negative endothelial cells

(2010) Guoquan Meng et al.   BRITISH JOURNAL OF PHARMACOLOGY

Berberine ameliorates TNBS-induced colitis by inhibiting lipid peroxidation, enterobacterial growth and NF-κB activation

(2010) In-Ah Lee et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Berberine Inhibits Inflammatory Response and Ameliorates Insulin Resistance in Hepatocytes

(2010) Tianjiong Lou et al.   INFLAMMATION

TNFα-induced and berberine-antagonized tight junction barrier impairment via tyrosine kinase, Akt and NFκB signaling

(2010) Maren Amasheh et al.   JOURNAL OF CELL SCIENCE

Berberine suppresses neuroinflammatory responses through AMP-activated protein kinase activation in BV-2 microglia

(2010) Dah-Yuu Lu et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Anti-atherogenic effect of San-Huang-Xie-Xin-Tang, a traditional Chinese medicine, in cultured human aortic smooth muscle cells

(2010) Yung-Song Wang et al.   JOURNAL OF ETHNOPHARMACOLOGY

Multidrug Resistance Proteins Restrain the Intestinal Absorption of trans-Resveratrol in Rats

(2010) M. Emília Juan et al.   JOURNAL OF NUTRITION

Berberine attenuates lipopolysaccharide-induced extracelluar matrix accumulation and inflammation in rat mesangial cells: Involvement of NF-κB signaling pathway

(2010) Qin Jiang et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Berberine Inhibits HIV Protease Inhibitor-Induced Inflammatory Response by Modulating ER Stress Signaling Pathways in Murine Macrophages

(2010) Weibin Zha et al.   PLoS One

Berberine suppresses proinflammatory responses through AMPK activation in macrophages

(2009) Hyun Woo Jeong et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Inhibitory effect of baicalein on IL-6-mediated signaling cascades in human myeloma cells

(2009) Shangqin Liu et al.   EUROPEAN JOURNAL OF HAEMATOLOGY

Metabolism and Pharmacokinetics of San-Huang-Xie-Xin-Tang, a Polyphenol-Rich Chinese Medicine Formula, in Rats andEx-VivoAntioxidant Activity

(2009) Chi-Sheng Shia et al.   Evidence-based Complementary and Alternative Medicine

Berberine reduces both MMP-9 and EMMPRIN expression through prevention of p38 pathway activation in PMA-induced macrophages

(2009) Zhouqing Huang et al.   INTERNATIONAL JOURNAL OF CARDIOLOGY

Berberine Differentially Modulates the Activities of ERK, p38 MAPK, and JNK to Suppress Th17 and Th1 T Cell Differentiation in Type 1 Diabetic Mice

(2009) Guoliang Cui et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Effective constituents in Xiexin Decoction for anti-inflammation

(2009) Bing-Liang Ma et al.   JOURNAL OF ETHNOPHARMACOLOGY

Potential ex vivo immunomodulatory effects of San-Huang-Xie-Xin-Tang and its component herbs on mice and humans

(2009) Chia-Yang Li et al.   JOURNAL OF ETHNOPHARMACOLOGY

Emodin suppresses cell proliferation and fibronectin expression via p38MAPK pathway in rat mesangial cells cultured under high glucose

(2009) Xuejuan Li et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Berberine Modifies Cysteine 179 of I B  Kinase, Suppresses Nuclear Factor- B-Regulated Antiapoptotic Gene Products, and Potentiates Apoptosis

(2008) M. K. Pandey et al.   CANCER RESEARCH