Berberine Protects against Neuronal Damage via Suppression of Glia-Mediated Inflammation in Traumatic Brain Injury

Effect of berberine on cell cycle arrest and cell survival during cerebral ischemia and reperfusion and correlations with p53/cyclin D1 and PI3K/Akt

(2013) Yu-Shuang Chai et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Absence of TLR4 Reduces Neurovascular Unit and Secondary Inflammatory Process after Traumatic Brain Injury in Mice

(2013) Akbar Ahmad et al.   PLoS One

Oxidative Burst of Circulating Neutrophils Following Traumatic Brain Injury in Human

(2013) Yiliu Liao et al.   PLoS One

Tissue Distribution of Berberine and Its Metabolites after Oral Administration in Rats

(2013) Xiang-Shan Tan et al.   PLoS One

Berberine Ameliorates Experimental Autoimmune Neuritis by Suppressing both Cellular and Humoral Immunity

(2013) H. Li et al.   SCANDINAVIAN JOURNAL OF IMMUNOLOGY

Neuroprotection of early and short-time applying berberine in the acute phase of cerebral ischemia: Up-regulated pAkt, pGSK and pCREB, down-regulated NF-κB expression, ameliorated BBB permeability

(2012) Xiaolin Zhang et al.   BRAIN RESEARCH

Bererine induces peripheral lymphocytes immune regulations to realize its neuroprotective effects in the cerebral ischemia/reperfusion mice

(2012) Bing Song et al.   CELLULAR IMMUNOLOGY

A Review of Neuroprotection Pharmacology and Therapies in Patients with Acute Traumatic Brain Injury

(2012) Kevin W. McConeghy et al.   CNS DRUGS

Berberine suppresses amyloid-beta-induced inflammatory response in microglia by inhibiting nuclear factor-kappaB and mitogen-activated protein kinase signalling pathways

(2012) Liyun Jia et al.   JOURNAL OF PHARMACY AND PHARMACOLOGY

Berberine ameliorates β-amyloid pathology, gliosis, and cognitive impairment in an Alzheimer's disease transgenic mouse model

(2012) Siva Sundara Kumar Durairajan et al.   NEUROBIOLOGY OF AGING

Wogonin Improves Histological and Functional Outcomes, and Reduces Activation of TLR4/NF-κB Signaling after Experimental Traumatic Brain Injury

(2012) Chien-Cheng Chen et al.   PLoS One

Salidroside Improves Behavioral and Histological Outcomes and Reduces Apoptosis via PI3K/Akt Signaling after Experimental Traumatic Brain Injury

(2012) Szu-Fu Chen et al.   PLoS One

Berberine protects against lipopolysaccharide-induced intestinal injury in mice via alpha 2 adrenoceptor-independent mechanisms

(2011) Hong-mei Li et al.   ACTA PHARMACOLOGICA SINICA

Caveolin-1 Deletion Reduces Early Brain Injury after Experimental Intracerebral Hemorrhage

(2011) Che-Feng Chang et al.   AMERICAN JOURNAL OF PATHOLOGY

PI3K p55γ promoter activity enhancement is involved in the anti-apoptotic effect of berberine against cerebral ischemia–reperfusion

(2011) Jun Hu et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Minocycline Restores sAPPα Levels and Reduces the Late Histopathological Consequences of Traumatic Brain Injury in Mice

(2011) Eleni Siopi et al.   JOURNAL OF NEUROTRAUMA

Neural injury following stroke: are Toll-like receptors the link between the immune system and the CNS?

(2010) Catherine E Downes et al.   BRITISH JOURNAL OF PHARMACOLOGY

Preventive effect of Coptis chinensis and berberine on intestinal injury in rats challenged with lipopolysaccharides

(2010) Qian Zhang et al.   FOOD AND CHEMICAL TOXICOLOGY

TNFα-induced and berberine-antagonized tight junction barrier impairment via tyrosine kinase, Akt and NFκB signaling

(2010) Maren Amasheh et al.   JOURNAL OF CELL SCIENCE

Berberine suppresses neuroinflammatory responses through AMP-activated protein kinase activation in BV-2 microglia

(2010) Dah-Yuu Lu et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Role of CCL2 (MCP-1) in Traumatic Brain Injury (TBI): Evidence from Severe TBI Patients and CCL2−/− Mice

(2010) Bridgette D Semple et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

The Cytokine Response to Human Traumatic Brain Injury: Temporal Profiles and Evidence for Cerebral Parenchymal Production

(2010) Adel Helmy et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Inflammatory Neurodegeneration and Mechanisms of Microglial Killing of Neurons

(2010) Guy C. Brown et al.   MOLECULAR NEUROBIOLOGY

Improving Bioscience Research Reporting: The ARRIVE Guidelines for Reporting Animal Research

(2010) Carol Kilkenny et al.   PLOS BIOLOGY

Pathology and new players in the pathogenesis of brain edema

(2009) Sukriti Nag et al.   ACTA NEUROPATHOLOGICA

Berberine prevents hyperglycemia-induced endothelial injury and enhances vasodilatation via adenosine monophosphate-activated protein kinase and endothelial nitric oxide synthase

(2009) Yiqun Wang et al.   CARDIOVASCULAR RESEARCH

Berberine: a plant alkaloid with therapeutic potential for central nervous system disorders

(2009) S. K. Kulkarni et al.   PHYTOTHERAPY RESEARCH

Activation of AMPK attenuates neutrophil proinflammatory activity and decreases the severity of acute lung injury

(2008) Xia Zhao et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Post-injury baicalein improves histological and functional outcomes and reduces inflammatory cytokines after experimental traumatic brain injury

(2008) S-F Chen et al.   BRITISH JOURNAL OF PHARMACOLOGY

Signaling by death receptors in the nervous system

(2008) Georg Haase et al.   CURRENT OPINION IN NEUROBIOLOGY

Neuroprotective effects of berberine on stroke models in vitro and in vivo

(2008) Xi-Qiao Zhou et al.   NEUROSCIENCE LETTERS

The role of inflammation in CNS injury and disease

(2006) Sian-Marie Lucas et al.   BRITISH JOURNAL OF PHARMACOLOGY