Autophagy and ionizing radiation in tumors: The “survive or not survive” dilemma

Guidelines for the use and interpretation of assays for monitoring autophagy in higher eukaryotes

(2014) Daniel J. Klionsky et al.   Autophagy

Autophagy upregulation by inhibitors of caspase-3 and mTOR enhances radiotherapy in a mouse model of lung cancer

(2014) Kwang Woon Kim et al.   Autophagy

Anti-cancer agent siramesine is a lysosomotropic detergent that induces cytoprotective autophagosome accumulation

(2014) Marie Stampe Ostenfeld et al.   Autophagy

The amplified cancer gene LAPTM4B promotes tumor growth and tolerance to stress through the induction of autophagy

(2012) Yang Li et al.   Autophagy

Targeting HMGB1-mediated autophagy as a novel therapeutic strategy for osteosarcoma

(2012) Jun Huang et al.   Autophagy

Andrographolide sensitizes cisplatin-induced apoptosis via suppression of autophagosome-lysosome fusion in human cancer cells

(2012) Jing Zhou et al.   Autophagy

Different involvement of autophagy in human malignant glioma cell lines undergoing irradiation and temozolomide combined treatments

(2012) Silvia Palumbo et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Paclitaxel resistance is associated with switch from apoptotic to autophagic cell death in MCF-7 breast cancer cells

(2012) G M A Ajabnoor et al.   Cell Death & Disease

Prognostic significance of Beclin 1 in intrahepatic cholangiocellular carcinoma

(2011) Li-Wei Dong et al.   Autophagy

Silencing of cellular prion protein (PrPC) expression by DNA-antisense oligonucleotides induces autophagy-dependent cell death in glioma cells

(2011) Giulia Barbieri et al.   Autophagy

MG-2477, a new tubulin inhibitor, induces autophagy through inhibition of the Akt/mTOR pathway and delayed apoptosis in A549 cells

(2011) Giampietro Viola et al.   BIOCHEMICAL PHARMACOLOGY

Sensitizing effect of 3-methyladenine on radiation-induced cytotoxicity in radio-resistant HepG2 cells in vitro and in tumor xenografts

(2011) Hsien-Chun Tseng et al.   CHEMICO-BIOLOGICAL INTERACTIONS

Induction of autophagy promotes differentiation of glioma-initiating cells and their radiosensitivity

(2011) Wenzhuo Zhuang et al.   INTERNATIONAL JOURNAL OF CANCER

The Zinc Ionophore PCI-5002 Radiosensitizes Non-small Cell Lung Cancer Cells by Enhancing Autophagic Cell Death

(2011) Kwang Woon Kim et al.   Journal of Thoracic Oncology

Cilengitide induces autophagy-mediated cell death in glioma cells

(2011) S. L. Lomonaco et al.   NEURO-ONCOLOGY

Autophagy contributes to resistance of tumor cells to ionizing radiation

(2011) Hassan Chaachouay et al.   RADIOTHERAPY AND ONCOLOGY

Combination treatment with arsenic trioxide and irradiation enhances cell-killing effects in human fibrosarcoma cells in vitro and in vivo through induction of both autophagy and apoptosis

(2010) Hui-Wen Chiu et al.   Autophagy

Bacillus Calmette-Guerin cell wall cytoskeleton enhances colon cancer radiosensitivity through autophagy

(2010) Jae-Min Yuk et al.   Autophagy

Autophagy in endometrial carcinomas and prognostic relevance of 'stone-like' structures (SLS): What is destined for the atypical endometrial hyperplasia?

(2010) Efthimios Sivridis et al.   Autophagy

Embryonic stem cell (ESC)-mediated transgene delivery induces growth suppression, apoptosis and radiosensitization and overcomes temozolomide resistance in malignant gliomas

(2010) I M Germano et al.   CANCER GENE THERAPY

Light-Chain 3A Autophagic Activity and Prognostic Significance in Non-small Cell Lung Carcinomas

(2010) Georgia Karpathiou et al.   CHEST

Autophagy inhibition contributes to radiation sensitization of esophageal squamous carcinoma cells

(2010) Y. S. Chen et al.   DISEASES OF THE ESOPHAGUS

Preclinical testing of the Akt inhibitor triciribine in T-cell acute lymphoblastic leukemia

(2010) Camilla Evangelisti et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Prognostic relevance of light chain 3 (LC3A) autophagy patterns in colorectal adenocarcinomas

(2010) A. Giatromanolaki et al.   JOURNAL OF CLINICAL PATHOLOGY

Targeting Epidermal Growth Factor Receptor-Associated Signaling Pathways in Non-Small Cell Lung Cancer Cells: Implication in Radiation Response

(2010) E. J. Choi et al.   MOLECULAR CANCER RESEARCH

The role of autophagy in sensitizing malignant glioma cells to radiation therapy

(2009) W. Zhuang et al.   ACTA BIOCHIMICA ET BIOPHYSICA SINICA

Prognostic significance of Beclin 1-dependent apoptotic activity in hepatocellular carcinoma

(2009) Ying-Hong Shi et al.   Autophagy

The prognostic role of Beclin 1 protein expression in high-grade gliomas

(2009) Luigi Pirtoli et al.   Autophagy

Combined Bcl-2/Mammalian Target of Rapamycin Inhibition Leads to Enhanced Radiosensitization via Induction of Apoptosis and Autophagy in Non-Small Cell Lung Tumor Xenograft Model

(2009) K. W. Kim et al.   CLINICAL CANCER RESEARCH

Beclin 1 and LC3 autophagic gene expression in cutaneous melanocytic lesions

(2009) Clelia Miracco et al.   HUMAN PATHOLOGY

The induction of autophagy by γ-radiation contributes to the radioresistance of glioma stem cells

(2009) Stephanie L. Lomonaco et al.   INTERNATIONAL JOURNAL OF CANCER

Promotion of autophagy as a mechanism for radiation sensitization of breast tumor cells

(2009) David A. Gewirtz et al.   RADIOTHERAPY AND ONCOLOGY

High-LET radiation combined with oxaliplatin induce autophagy in U-87 glioblastoma cells

(2008) Sami Benzina et al.   CANCER LETTERS

Synergistic Tumor-Killing Effect of Radiation and Berberine Combined Treatment in Lung Cancer: The Contribution of Autophagic Cell Death

(2008) Pei-ling Peng et al.   INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS

Autophagic cell death: the story of a misnomer

(2008) Guido Kroemer et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY