NFAT3 and TGF-β/SMAD3 regulate the expression of miR-140 in osteoarthritis

A role for age-related changes in TGFβ signaling in aberrant chondrocyte differentiation and osteoarthritis

(2012) Peter M van der Kraan et al.   ARTHRITIS RESEARCH & THERAPY

NF-AT5 is a critical regulator of inflammatory arthritis

(2011) Hyung-Ju Yoon et al.   ARTHRITIS AND RHEUMATISM

MicroRNA-22 and microRNA-140 suppress NF-κB activity by regulating the expression of NF-κB coactivators

(2011) Akemi Takata et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

MiR-140 is co-expressed withWwp2-Ctranscript and activated by Sox9 to targetSp1in maintaining the chondrocyte proliferation

(2011) Jun Yang et al.   FEBS LETTERS

Selective targeting of activating and inhibitory Smads by distinct WWP2 ubiquitin ligase isoforms differentially modulates TGFβ signalling and EMT

(2011) S M Soond et al.   ONCOGENE

Protein Kinase A Regulates Molecular Chaperone Transcription and Protein Aggregation

(2011) Yue Zhang et al.   PLoS One

Modulation of transforming growth factor beta signalling pathway genes by transforming growth factor beta in human osteoarthritic chondrocytes: involvement of Sp1 in both early and late response cells to transforming growth factor beta

(2011) Catherine Baugé et al.   ARTHRITIS RESEARCH & THERAPY

Genetic variation in the SMAD3 gene is associated with hip and knee osteoarthritis

(2010) Ana M. Valdes et al.   ARTHRITIS AND RHEUMATISM

MicroRNA-140 plays dual roles in both cartilage development and homeostasis

(2010) S. Miyaki et al.   GENES & DEVELOPMENT

Sequential Activation of NFAT and c-Myc Transcription Factors Mediates the TGF-β Switch from a Suppressor to a Promoter of Cancer Cell Proliferation

(2010) Garima Singh et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

HDAC4 Represses Matrix Metalloproteinase-13 Transcription in Osteoblastic Cells, and Parathyroid Hormone Controls This Repression

(2010) Emi Shimizu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Gain of miR-151 on chromosome 8q24.3 facilitates tumour cell migration and spreading through downregulating RhoGDIA

(2010) Jie Ding et al.   NATURE CELL BIOLOGY

Structure and activity of putative intronic miRNA promoters

(2010) A. M. Monteys et al.   RNA

Analyzing mRNA expression identifies Smad3 as a microRNA-140 target regulated only at protein level

(2010) H. Pais et al.   RNA

Hyperosmolarity regulates SOX9 mRNA posttranscriptionally in human articular chondrocytes

(2009) Simon R. Tew et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

MicroRNA-140 is expressed in differentiated human articular chondrocytes and modulates interleukin-1 responses

(2009) Shigeru Miyaki et al.   ARTHRITIS AND RHEUMATISM

Regulation of the IGFBP-5 and MMP-13 genes by the microRNAs miR-140 and miR-27a in human osteoarthritic chondrocytes

(2009) Ginette Tardif et al.   BMC MUSCULOSKELETAL DISORDERS

Hsp90  and p130cas: novel regulatory factors of MMP-13 expression in human osteoarthritic chondrocytes

(2008) Z Fan et al.   ANNALS OF THE RHEUMATIC DISEASES

Differential upregulation of the three transforming growth factor beta isoforms in human osteoarthritic cartilage

(2008) M Pombo-Suarez et al.   ANNALS OF THE RHEUMATIC DISEASES

Expression of microRNA-146 in rheumatoid arthritis synovial tissue

(2008) Tomoyuki Nakasa et al.   ARTHRITIS AND RHEUMATISM

Altered expression of MicroRNA in synovial fibroblasts and synovial tissue in rheumatoid arthritis

(2008) Joanna Stanczyk et al.   ARTHRITIS AND RHEUMATISM

Independent transcription of miR-281 in the intron of ODA in Drosophila melanogaster

(2008) Huiping Xiong et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Nicotine modulates expression of miR-140*, which targets the 3′-untranslated region of dynamin 1 gene (Dnm1)

(2008) Weihua Huang et al.   INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY

ADAMTS5−/− mice have less subchondral bone changes after induction of osteoarthritis through surgical instability: implications for a link between cartilage and subchondral bone changes

(2008) S.M. Botter et al.   OSTEOARTHRITIS AND CARTILAGE

The identification of differentially expressed microRNA in osteoarthritic tissue that modulate the production of TNF-α and MMP13

(2008) S.W. Jones et al.   OSTEOARTHRITIS AND CARTILAGE

Integrative MicroRNA and Proteomic Approaches Identify Novel Osteoarthritis Genes and Their Collaborative Metabolic and Inflammatory Networks

(2008) Dimitrios Iliopoulos et al.   PLoS One