Transcription Factor Snail Regulates Tumor Necrosis Factor α-Mediated Synovial Fibroblast Activation in the Rheumatoid Joint

Origin and function of myofibroblasts in kidney fibrosis

(2013) Valerie S LeBleu et al.   NATURE MEDICINE

The problem of choice: current biologic agents and future prospects in RA

(2013) Ernest H. Choy et al.   Nature Reviews Rheumatology

To Wnt or not to Wnt: the bone and joint health dilemma

(2013) Rik J. Lories et al.   Nature Reviews Rheumatology

Pressure and inflammatory stimulation induced increase of cadherin-11 is mediated by PI3K/Akt pathway in synovial fibroblasts from temporomandibular joint

(2013) M. Wu et al.   OSTEOARTHRITIS AND CARTILAGE

Unraveling the signaling pathways promoting fibrosis in Dupuytren's disease reveals TNF as a therapeutic target

(2013) L. S. Verjee et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Identification of Cadherin 11 as a Mediator of Dermal Fibrosis and Possible Role in Systemic Sclerosis

(2013) Minghua Wu et al.   Arthritis & Rheumatology

Brief Report: Amelioration of collagen-induced arthritis in mice by lentivirus-mediated silencing of microRNA-223

(2012) Yuan-Tsung Li et al.   ARTHRITIS AND RHEUMATISM

Myofibroblasts

(2012) Biao Hu et al.   CURRENT OPINION IN RHEUMATOLOGY

Snail/Gfi-1 (SNAG) family zinc finger proteins in transcription regulation, chromatin dynamics, cell signaling, development, and disease

(2012) Cindy Chiang et al.   CYTOKINE & GROWTH FACTOR REVIEWS

Mechanisms of fibrosis: therapeutic translation for fibrotic disease

(2012) Thomas A Wynn et al.   NATURE MEDICINE

Duality of fibroblast-like synoviocytes in RA: passive responders and imprinted aggressors

(2012) Nunzio Bottini et al.   Nature Reviews Rheumatology

TGFbeta Family Members Are Key Mediators in the Induction of Myofibroblast Phenotype of Human Adipose Tissue Progenitor Cells by Macrophages

(2012) Virginie Bourlier et al.   PLoS One

The Ins and Outs of the Epithelial to Mesenchymal Transition in Health and Disease

(2011) M. Angela Nieto   Annual Review of Cell and Developmental Biology

A p53/miRNA-34 axis regulates Snail1-dependent cancer cell epithelial–mesenchymal transition

(2011) Nam Hee Kim et al.   JOURNAL OF CELL BIOLOGY

Safety of biologic therapy in rheumatoid arthritis

(2011) Robert S. Woodrick et al.   Nature Reviews Rheumatology

The Pathogenesis of Rheumatoid Arthritis

(2011) Iain B. McInnes et al.   NEW ENGLAND JOURNAL OF MEDICINE

Cadherin-11 regulates fibroblast inflammation

(2011) S. K. Chang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The tumour-associated glycoprotein podoplanin is expressed in fibroblast-like synoviocytes of the hyperplastic synovial lining layer in rheumatoid arthritis

(2011) Anna-Karin H Ekwall et al.   ARTHRITIS RESEARCH & THERAPY

Snail1 transcription factor is a critical mediator of hepatic stellate cell activation following hepatic injury

(2010) Melania Scarpa et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Slug suppression induces apoptosis via Puma transactivation in rheumatoid arthritis fibroblast-like synoviocytes treated with hydrogen peroxide

(2010) Hoon-Suk Cha et al.   EXPERIMENTAL AND MOLECULAR MEDICINE

p53 inhibits tumor cell invasion via the degradation of snail protein in hepatocellular carcinoma

(2010) Seung-Oe Lim et al.   FEBS LETTERS

Gene delivery of TGF-β1 induces arthrofibrosis and chondrometaplasia of synovium in vivo

(2010) Rachael S Watson et al.   LABORATORY INVESTIGATION

Antitumor effect of novel small chemical inhibitors of Snail-p53 binding in K-Ras-mutated cancer cells

(2010) S-H Lee et al.   ONCOGENE

Cadherin 11 promotes invasive behavior of fibroblast-like synoviocytes

(2009) Hans P. Kiener et al.   ARTHRITIS AND RHEUMATISM

Amelioration of experimental arthritis by a telomerase-dependent conditionally replicating adenovirus that targets synovial fibroblasts

(2009) Shih-Yao Chen et al.   ARTHRITIS AND RHEUMATISM

Fibroblast-like synoviocytes in inflammatory arthritis pathology: the emerging role of cadherin-11

(2009) Sook Kyung Chang et al.   IMMUNOLOGICAL REVIEWS

Mesenchymal cells reactivate Snail1 expression to drive three-dimensional invasion programs

(2009) R. Grant Rowe et al.   JOURNAL OF CELL BIOLOGY

Treatment of Idiopathic Pulmonary Fibrosis with Etanercept

(2008) Ganesh Raghu et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Amelioration of collagen-induced arthritis in rats by adenovirus-mediated PTEN gene transfer

(2008) Chrong-Reen Wang et al.   ARTHRITIS AND RHEUMATISM

Tumor necrosis factor α drives cadherin 11 expression in rheumatoid inflammation

(2008) Bernard Vandooren et al.   ARTHRITIS AND RHEUMATISM

TNFα is required for cholestasis-induced liver fibrosis in the mouse

(2008) Erwin Gäbele et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Repression of PTEN Phosphatase by Snail1 Transcriptional Factor during Gamma Radiation-Induced Apoptosis

(2008) M. Escriva et al.   MOLECULAR AND CELLULAR BIOLOGY