Tiny giants of gene regulation: experimental strategies for microRNA functional studies
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Title
Tiny giants of gene regulation: experimental strategies for microRNA functional studies
Authors
Keywords
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Journal
Wiley Interdisciplinary Reviews-Developmental Biology
Volume 5, Issue 3, Pages 311-362
Publisher
Wiley
Online
2016-03-08
DOI
10.1002/wdev.223
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Note: Only part of the references are listed.- Combined Label-Free Quantitative Proteomics and microRNA Expression Analysis of Breast Cancer Unravel Molecular Differences with Clinical Implications
- (2015) Angelo Gámez-Pozo et al. CANCER RESEARCH
- The BRAF Pseudogene Functions as a Competitive Endogenous RNA and Induces Lymphoma In Vivo
- (2015) Florian A. Karreth et al. CELL
- Single-Molecule Imaging Reveals that Argonaute Reshapes the Binding Properties of Its Nucleic Acid Guides
- (2015) William E. Salomon et al. CELL
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- (2015) Stanley D. Chandradoss et al. CELL
- Hepatitis C Virus RNA Functionally Sequesters miR-122
- (2015) Joseph M. Luna et al. CELL
- The let-7 microRNA Directs Vulval Development through a Single Target
- (2015) Matyas Ecsedi et al. DEVELOPMENTAL CELL
- Identification of the receptor tyrosine kinases (RTKs)-oriented functional targets of miR-206 by an antibody-based protein array
- (2015) Yazhou Cui et al. FEBS LETTERS
- microRNAs That Promote or Inhibit Memory Formation in Drosophila melanogaster
- (2015) Germain U. Busto et al. GENETICS
- miRNA-26b Overexpression in Ulcerative Colitis-associated Carcinogenesis
- (2015) Natalya Benderska et al. INFLAMMATORY BOWEL DISEASES
- Dysregulation of microRNA-219 promotes neurodegeneration through post-transcriptional regulation of tau
- (2015) Ismael Santa-Maria et al. JOURNAL OF CLINICAL INVESTIGATION
- Stable isotope labelling methods in mass spectrometry-based quantitative proteomics
- (2015) Osama Chahrour et al. JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS
- PTEN ceRNA networks in human cancer
- (2015) Laura Poliseno et al. METHODS
- Human Argonaute 2 Has Diverse Reaction Pathways on Target RNAs
- (2015) Myung Hyun Jo et al. MOLECULAR CELL
- Analysis of intronic and exonic reads in RNA-seq data characterizes transcriptional and post-transcriptional regulation
- (2015) Dimos Gaidatzis et al. NATURE BIOTECHNOLOGY
- miRWalk2.0: a comprehensive atlas of microRNA-target interactions
- (2015) Harsh Dweep et al. NATURE METHODS
- High-throughput functional genomics using CRISPR–Cas9
- (2015) Ophir Shalem et al. NATURE REVIEWS GENETICS
- miR-130a activates apoptotic signaling through activation of caspase-8 in taxane-resistant prostate cancer cells
- (2015) Yasunori Fujita et al. PROSTATE
- MicroRNA control of protein expression noise
- (2015) J. M. Schmiedel et al. SCIENCE
- A transgenic resource for conditional competitive inhibition of conserved Drosophila microRNAs
- (2015) Tudor A. Fulga et al. Nature Communications
- MicroRNA-Dependent Transcriptional Silencing of Transposable Elements in Drosophila Follicle Cells
- (2015) Bruno Mugat et al. PLoS Genetics
- Downregulation of the Host Gene jigr1 by miR-92 Is Essential for Neuroblast Self-Renewal in Drosophila
- (2015) Yeliz Yuva-Aydemir et al. PLoS Genetics
- Computational Biology in microRNA
- (2015) Yue Li et al. Wiley Interdisciplinary Reviews-RNA
- microRNAs That Promote or Inhibit Memory Formation in Drosophila melanogaster
- (2015) Germain U. Busto et al. GENETICS
- Small indels induced by CRISPR/Cas9 in the 5′ region of microRNA lead to its depletion and Drosha processing retardance
- (2015) Qian Jiang et al. RNA Biology
- MicroRNA Target Identification: Lessons from HypoxamiRs
- (2014) Thomas Bertero et al. ANTIOXIDANTS & REDOX SIGNALING
- miRNA-128 Suppresses Prostate Cancer by Inhibiting BMI-1 to Inhibit Tumor-Initiating Cells
- (2014) M. Jin et al. CANCER RESEARCH
- Development and Applications of CRISPR-Cas9 for Genome Engineering
- (2014) Patrick D. Hsu et al. CELL
- Detection of miRNA Expression in Intact Cells Using Activatable Sensor Oligonucleotides
- (2014) Byunghee Yoo et al. CHEMISTRY & BIOLOGY
- miR-8 controls synapse structure by repression of the actin regulator Enabled
- (2014) Carlos M. Loya et al. DEVELOPMENT
- Systematic Study of Drosophila MicroRNA Functions Using a Collection of Targeted Knockout Mutations
- (2014) Ya-Wen Chen et al. DEVELOPMENTAL CELL
- Global microRNA depletion suppresses tumor angiogenesis
- (2014) S. Chen et al. GENES & DEVELOPMENT
- Affinity Purification of Binding miRNAs for Messenger RNA Fused with a Common Tag
- (2014) Ke Wei et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Hunting the Needle in the Haystack: A Guide to Obtain Biologically Meaningful MicroRNA Targets
- (2014) Michael Karbiener et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Dosage and Temporal Thresholds in microRNA Proteomics
- (2014) Thomas Lee et al. MOLECULAR & CELLULAR PROTEOMICS
- Global Analyses of the Effect of Different Cellular Contexts on MicroRNA Targeting
- (2014) Jin-Wu Nam et al. MOLECULAR CELL
- Principles and Properties of Eukaryotic mRNPs
- (2014) Sarah F. Mitchell et al. MOLECULAR CELL
- Unambiguous Identification of miRNA:Target Site Interactions by Different Types of Ligation Reactions
- (2014) Stefanie Grosswendt et al. MOLECULAR CELL
- Assessing the ceRNA Hypothesis with Quantitative Measurements of miRNA and Target Abundance
- (2014) Rémy Denzler et al. MOLECULAR CELL
- Endogenous miRNA and Target Concentrations Determine Susceptibility to Potential ceRNA Competition
- (2014) Andrew D. Bosson et al. MOLECULAR CELL
- mRNA Destabilization Is the Dominant Effect of Mammalian MicroRNAs by the Time Substantial Repression Ensues
- (2014) Stephen W. Eichhorn et al. MOLECULAR CELL
- The multilayered complexity of ceRNA crosstalk and competition
- (2014) Yvonne Tay et al. NATURE
- Detecting and characterizing circular RNAs
- (2014) William R Jeck et al. NATURE BIOTECHNOLOGY
- miR-CLIP capture of a miRNA targetome uncovers a lincRNA H19–miR-106a interaction
- (2014) Jochen Imig et al. Nature Chemical Biology
- Mapping Argonaute and conventional RNA-binding protein interactions with RNA at single-nucleotide resolution using HITS-CLIP and CIMS analysis
- (2014) Michael J Moore et al. Nature Protocols
- A guide to genome engineering with programmable nucleases
- (2014) Hyongbum Kim et al. NATURE REVIEWS GENETICS
- Ribosome profiling: new views of translation, from single codons to genome scale
- (2014) Nicholas T. Ingolia NATURE REVIEWS GENETICS
- Identification and consequences of miRNA–target interactions — beyond repression of gene expression
- (2014) Jean Hausser et al. NATURE REVIEWS GENETICS
- Regulation of microRNA biogenesis
- (2014) Minju Ha et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
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- (2014) Jennifer Y Tan et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Rapid identification of regulatory microRNAs by miTRAP (miRNA trapping by RNA in vitro affinity purification)
- (2014) Juliane Braun et al. NUCLEIC ACIDS RESEARCH
- DIANA-TarBase v7.0: indexing more than half a million experimentally supported miRNA:mRNA interactions
- (2014) Ioannis S. Vlachos et al. NUCLEIC ACIDS RESEARCH
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- (2014) Tsui-Ting Ho et al. NUCLEIC ACIDS RESEARCH
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- (2014) C. S. Lu et al. PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES
- Macros in microRNA target identification
- (2014) Shikha Tarang et al. RNA Biology
- A TALEN-based strategy for efficient bi-allelic miRNA ablation in human cells
- (2014) C. Uhde-Stone et al. RNA
- Understanding functional miRNA–target interactions in vivo by site-specific genome engineering
- (2014) Andrew R. Bassett et al. Nature Communications
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- (2014) Peter M. Clark et al. Scientific Reports
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- (2014) Yi-Chien Lu et al. Cell Reports
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- (2014) Joseph M Ziegelbauer Current Opinion in Virology
- Seq and CLIP through the miRNA world
- (2014) Nitish Mittal et al. GENOME BIOLOGY
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- (2014) Tao Wang et al. GENOME BIOLOGY
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- (2014) Thalia A Farazi et al. GENOME BIOLOGY
- PIPE-CLIP: a comprehensive online tool for CLIP-seq data analysis
- (2014) Beibei Chen et al. GENOME BIOLOGY
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- (2013) Miao Shi et al. ANALYTICAL BIOCHEMISTRY
- Mapping the Human miRNA Interactome by CLASH Reveals Frequent Noncanonical Binding
- (2013) Aleksandra Helwak et al. CELL
- Drosophila miR-932 modulates hedgehog signaling by targeting its co-receptor Brother of ihog
- (2013) Lei Gao et al. DEVELOPMENTAL BIOLOGY
- Identification of potential microRNA–target pairs associated with osteopetrosis by deep sequencing, iTRAQ proteomics and bioinformatics
- (2013) Minglin Ou et al. EUROPEAN JOURNAL OF HUMAN GENETICS
- Analysis of CDS-located miRNA target sites suggests that they can effectively inhibit translation
- (2013) J. Hausser et al. GENOME RESEARCH
- Where we stand, where we are moving: Surveying computational techniques for identifying miRNA genes and uncovering their regulatory role
- (2013) Dimitrios Kleftogiannis et al. JOURNAL OF BIOMEDICAL INFORMATICS
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- (2013) W. Li et al. JOURNAL OF NEUROSCIENCE
- Identifying Argonaute binding sites in Caenorhabditis elegans using iCLIP
- (2013) James P. Broughton et al. METHODS
- iCLIP: Protein–RNA interactions at nucleotide resolution
- (2013) Ina Huppertz et al. METHODS
- Integrative Omics Analysis Reveals the Importance and Scope of Translational Repression in microRNA-mediated Regulation
- (2013) Qi Liu et al. MOLECULAR & CELLULAR PROTEOMICS
- Natural RNA circles function as efficient microRNA sponges
- (2013) Thomas B. Hansen et al. NATURE
- Circular RNAs are a large class of animal RNAs with regulatory potency
- (2013) Sebastian Memczak et al. NATURE
- MicroRNA target site identification by integrating sequence and binding information
- (2013) William H Majoros et al. NATURE METHODS
- A biophysical miRNA-mRNA interaction model infers canonical and noncanonical targets
- (2013) Mohsen Khorshid et al. NATURE METHODS
- System-wide identification of RNA-binding proteins by interactome capture
- (2013) Alfredo Castello et al. Nature Protocols
- Argonaute proteins: functional insights and emerging roles
- (2013) Gunter Meister NATURE REVIEWS GENETICS
- TALEN-based knockout library for human microRNAs
- (2013) Young-Kook Kim et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Treatment of HCV Infection by Targeting MicroRNA
- (2013) Harry L.A. Janssen et al. NEW ENGLAND JOURNAL OF MEDICINE
- MREdictor: a two-step dynamic interaction model that accounts for mRNA accessibility and Pumilio binding accurately predicts microRNA targets
- (2013) Danny Incarnato et al. NUCLEIC ACIDS RESEARCH
- starBase v2.0: decoding miRNA-ceRNA, miRNA-ncRNA and protein–RNA interaction networks from large-scale CLIP-Seq data
- (2013) Jun-Hao Li et al. NUCLEIC ACIDS RESEARCH
- Chromosomal deletions and inversions mediated by TALENs and CRISPR/Cas in zebrafish
- (2013) An Xiao et al. NUCLEIC ACIDS RESEARCH
- Isolation and identification of cell-specific microRNAs targeting a messenger RNA using a biotinylated anti-sense oligonucleotide capture affinity technique
- (2013) Tidi Hassan et al. NUCLEIC ACIDS RESEARCH
- DIANA-microT web server v5.0: service integration into miRNA functional analysis workflows
- (2013) Maria D. Paraskevopoulou et al. NUCLEIC ACIDS RESEARCH
- Miravirsen (SPC3649) can inhibit the biogenesis of miR-122
- (2013) Luca F. R. Gebert et al. NUCLEIC ACIDS RESEARCH
- Large-Scale Screens of miRNA-mRNA Interactions Unveiled That the 3′UTR of a Gene Is Targeted by Multiple miRNAs
- (2013) Peng Zhou et al. PLoS One
- Loss of ALS-associated TDP-43 in zebrafish causes muscle degeneration, vascular dysfunction, and reduced motor neuron axon outgrowth
- (2013) B. Schmid et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- 4-thiouridine inhibits rRNA synthesis and causes a nucleolar stress response
- (2013) Kaspar Burger et al. RNA Biology
- Suppression of microRNAs by dual-targeting and clustered Tough Decoy inhibitors
- (2013) Anne Kruse Hollensen et al. RNA Biology
- Genome-wide identification of translationally inhibited and degraded miR-155 targets using RNA-interacting protein-IP
- (2013) Jan Meier et al. RNA Biology
- Translational Repression and eIF4A2 Activity Are Critical for MicroRNA-Mediated Gene Regulation
- (2013) H. A. Meijer et al. SCIENCE
- Plasmid-based target protectors allow specific blockade of miRNA silencing activity in mammalian developmental systems
- (2013) Jennifer L. Knauss et al. Frontiers in Cellular Neuroscience
- Dampening the Signals Transduced through Hedgehog via MicroRNA miR-7 Facilitates Notch-Induced Tumourigenesis
- (2013) Vanina G. Da Ros et al. PLOS BIOLOGY
- Competition and collaboration between RNA-binding proteins and microRNAs
- (2013) J. J. David Ho et al. Wiley Interdisciplinary Reviews-RNA
- miRNA sponges: soaking up miRNAs for regulation of gene expression
- (2013) Rasmus O. Bak et al. Wiley Interdisciplinary Reviews-RNA
- PARma: identification of microRNA target sites in AGO-PAR-CLIP data
- (2013) Florian Erhard et al. GENOME BIOLOGY
- miR-TRAP: A Benchtop Chemical Biology Strategy to Identify microRNA Targets
- (2012) Huricha Baigude et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Functional microRNA targets in protein coding sequences
- (2012) Martin Reczko et al. BIOINFORMATICS
- Regulation of Circadian Behavioral Output via a MicroRNA-JAK/STAT Circuit
- (2012) Wenyu Luo et al. CELL
- Insights into RNA Biology from an Atlas of Mammalian mRNA-Binding Proteins
- (2012) Alfredo Castello et al. CELL
- Mutual Repression by Bantam miRNA and Capicua Links the EGFR/MAPK and Hippo Pathways in Growth Control
- (2012) Héctor Herranz et al. CURRENT BIOLOGY
- Drosophila miR-124 regulates neuroblast proliferation through its target anachronism
- (2012) R. Weng et al. DEVELOPMENT
- miR-92b regulates Mef2 levels through a negative-feedback circuit during Drosophila muscle development
- (2012) Z. Chen et al. DEVELOPMENT
- let-7-Complex MicroRNAs Regulate the Temporal Identity of Drosophila Mushroom Body Neurons via chinmo
- (2012) Yen-Chi Wu et al. DEVELOPMENTAL CELL
- EBV and human microRNAs co-target oncogenic and apoptotic viral and human genes during latency
- (2012) Kasandra J Riley et al. EMBO JOURNAL
- Pumilio facilitates miRNA regulation of the E2F3 oncogene
- (2012) W. O. Miles et al. GENES & DEVELOPMENT
- Extensive alternative polyadenylation during zebrafish development
- (2012) I. Ulitsky et al. GENOME RESEARCH
- RIP-chip-SRM--a new combinatorial large-scale approach identifies a set of translationally regulated bantam/miR-58 targets in C. elegans
- (2012) M. Jovanovic et al. GENOME RESEARCH
- Impact of miR-7 over-expression on the proteome of Chinese hamster ovary cells
- (2012) Paula Meleady et al. JOURNAL OF BIOTECHNOLOGY
- Identification of Novel miR-21 Target Proteins in Multiple Myeloma Cells by Quantitative Proteomics
- (2012) Qian Xiong et al. JOURNAL OF PROTEOME RESEARCH
- The hunting of targets: challenge in miRNA research
- (2012) F Akbari Moqadam et al. LEUKEMIA
- MS2-TRAP (MS2-tagged RNA affinity purification): Tagging RNA to identify associated miRNAs
- (2012) Je-Hyun Yoon et al. METHODS
- Functional validation of microRNA-target RNA interactions
- (2012) S. Vasudevan METHODS
- Argonaute CLIP – A method to identify in vivo targets of miRNAs
- (2012) Lukasz Jaskiewicz et al. METHODS
- Generation of miRNA sponge constructs
- (2012) Joost Kluiver et al. METHODS
- Genome-wide identification of miRNA targets by PAR-CLIP
- (2012) Markus Hafner et al. METHODS
- Transcriptome-wide miR-155 Binding Map Reveals Widespread Noncanonical MicroRNA Targeting
- (2012) Gabriel B. Loeb et al. MOLECULAR CELL
- Systematic Analysis of Tissue-Restricted miRISCs Reveals a Broad Role for MicroRNAs in Suppressing Basal Activity of the C. elegans Pathogen Response
- (2012) Brian A. Kudlow et al. MOLECULAR CELL
- The microRNA miR-34 modulates ageing and neurodegeneration in Drosophila
- (2012) Nan Liu et al. NATURE
- Long-term, efficient inhibition of microRNA function in mice using rAAV vectors
- (2012) Jun Xie et al. NATURE METHODS
- High-throughput assessment of microRNA activity and function using microRNA sensor and decoy libraries
- (2012) Gavriel Mullokandov et al. NATURE METHODS
- MicroRNAs and their targets: recognition, regulation and an emerging reciprocal relationship
- (2012) Amy E. Pasquinelli NATURE REVIEWS GENETICS
- An alternative mode of microRNA target recognition
- (2012) Sung Wook Chi et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- A potent 2′ -O- methylated RNA-based microRNA inhibitor with unique secondary structures
- (2012) Takeshi Haraguchi et al. NUCLEIC ACIDS RESEARCH
- miRGator v3.0: a microRNA portal for deep sequencing, expression profiling and mRNA targeting
- (2012) Sooyoung Cho et al. NUCLEIC ACIDS RESEARCH
- HuR protein attenuates miRNA-mediated repression by promoting miRISC dissociation from the target RNA
- (2012) Pradipta Kundu et al. NUCLEIC ACIDS RESEARCH
- Rapid Generation of MicroRNA Sponges for MicroRNA Inhibition
- (2012) Joost Kluiver et al. PLoS One
- Capturing microRNA targets using an RNA-induced silencing complex (RISC)-trap approach
- (2012) X. A. Cambronne et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Potent microRNA suppression by RNA Pol II-transcribed 'Tough Decoy' inhibitors
- (2012) R. O. Bak et al. RNA
- Association of Argonaute proteins and microRNAs can occur after cell lysis
- (2012) K. J. Riley et al. RNA
- miRNA-Mediated Gene Silencing by Translational Repression Followed by mRNA Deadenylation and Decay
- (2012) S. Djuranovic et al. SCIENCE
- Ribosome Profiling Shows That miR-430 Reduces Translation Before Causing mRNA Decay in Zebrafish
- (2012) A. A. Bazzini et al. SCIENCE
- A Resource for the Conditional Ablation of microRNAs in the Mouse
- (2012) Chong Yon Park et al. Cell Reports
- Ago HITS-CLIP Expands Understanding of Kaposi's Sarcoma-associated Herpesvirus miRNA Function in Primary Effusion Lymphomas
- (2012) Irina Haecker et al. PLoS Pathogens
- The Viral and Cellular MicroRNA Targetome in Lymphoblastoid Cell Lines
- (2012) Rebecca L. Skalsky et al. PLoS Pathogens
- Analysis of CLIP and iCLIP methods for nucleotide-resolution studies of protein-RNA interactions
- (2012) Yoichiro Sugimoto et al. GENOME BIOLOGY
- An Extensive MicroRNA-Mediated Network of RNA-RNA Interactions Regulates Established Oncogenic Pathways in Glioblastoma
- (2011) Pavel Sumazin et al. CELL
- Coding-Independent Regulation of the Tumor Suppressor PTEN by Competing Endogenous mRNAs
- (2011) Yvonne Tay et al. CELL
- In Vivo Identification of Tumor- Suppressive PTEN ceRNAs in an Oncogenic BRAF-Induced Mouse Model of Melanoma
- (2011) Florian A. Karreth et al. CELL
- Overlapping functions of microRNAs in control of apoptosis during Drosophila embryogenesis
- (2011) W Ge et al. CELL DEATH AND DIFFERENTIATION
- Viral MicroRNA Targetome of KSHV-Infected Primary Effusion Lymphoma Cell Lines
- (2011) Eva Gottwein et al. Cell Host & Microbe
- The Art of MicroRNA Research
- (2011) Eva van Rooij CIRCULATION RESEARCH
- Notch-mediated repression of bantam miRNA contributes to boundary formation in the Drosophila wing
- (2011) I. Becam et al. DEVELOPMENT
- miR-31 modulates dystrophin expression: new implications for Duchenne muscular dystrophy therapy
- (2011) Davide Cacchiarelli et al. EMBO REPORTS
- Unusually effective microRNA targeting within repeat-rich coding regions of mammalian mRNAs
- (2011) M. Schnall-Levin et al. GENOME RESEARCH
- Two-tiered Approach Identifies a Network of Cancer and Liver Disease-related Genes Regulated by miR-122
- (2011) Daniel R. Boutz et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Sponge Transgenic Mouse Model Reveals Important Roles for the MicroRNA-183 (miR-183)/96/182 Cluster in Postmitotic Photoreceptors of the Retina
- (2011) Qubo Zhu et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- miRWalk – Database: Prediction of possible miRNA binding sites by “walking” the genes of three genomes
- (2011) Harsh Dweep et al. JOURNAL OF BIOMEDICAL INFORMATICS
- Genome-wide Characterization ofmiR-34aInduced Changes in Protein and mRNA Expression by a Combined Pulsed SILAC and Microarray Analysis
- (2011) Markus Kaller et al. MOLECULAR & CELLULAR PROTEOMICS
- Integrative Regulatory Mapping Indicates that the RNA-Binding Protein HuR Couples Pre-mRNA Processing and mRNA Stability
- (2011) Neelanjan Mukherjee et al. MOLECULAR CELL
- Transcriptome-wide Analysis of Regulatory Interactions of the RNA-Binding Protein HuR
- (2011) Svetlana Lebedeva et al. MOLECULAR CELL
- A resource of vectors and ES cells for targeted deletion of microRNAs in mice
- (2011) Haydn M Prosser et al. NATURE BIOTECHNOLOGY
- Mapping in vivo protein-RNA interactions at single-nucleotide resolution from HITS-CLIP data
- (2011) Chaolin Zhang et al. NATURE BIOTECHNOLOGY
- miRNA regulation of Sdf1 chemokine signaling provides genetic robustness to germ cell migration
- (2011) Alison A Staton et al. NATURE GENETICS
- MicroRNAs can generate thresholds in target gene expression
- (2011) Shankar Mukherji et al. NATURE GENETICS
- Silencing of microRNA families by seed-targeting tiny LNAs
- (2011) Susanna Obad et al. NATURE GENETICS
- A quantitative analysis of CLIP methods for identifying binding sites of RNA-binding proteins
- (2011) Shivendra Kishore et al. NATURE METHODS
- Use of target protector morpholinos to analyze the physiological roles of specific miRNA-mRNA pairs in vivo
- (2011) Alison A Staton et al. Nature Protocols
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- Weak seed-pairing stability and high target-site abundance decrease the proficiency of lsy-6 and other microRNAs
- (2011) David M Garcia et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
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- (2011) Shuai Li et al. NUCLEIC ACIDS RESEARCH
- doRiNA: a database of RNA interactions in post-transcriptional regulation
- (2011) Gerd Anders et al. NUCLEIC ACIDS RESEARCH
- Experimental strategies for microRNA target identification
- (2011) D. W. Thomson et al. NUCLEIC ACIDS RESEARCH
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- (2011) K Schramedei et al. ONCOGENE
- Quantitative Proteomics Identify Novel miR-155 Target Proteins
- (2011) Christopher Lößner et al. PLoS One
- MultiMiTar: A Novel Multi Objective Optimization based miRNA-Target Prediction Method
- (2011) Ramkrishna Mitra et al. PLoS One
- Cross-linking, ligation, and sequencing of hybrids reveals RNA-RNA interactions in yeast
- (2011) G. Kudla et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Global identification of miR-373-regulated genes in breast cancer by quantitative proteomics
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- (2011) Matteo Osella et al. PLoS Computational Biology
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- (2011) Ashish Lal et al. PLoS Genetics
- Identification of RNA-protein interaction networks using PAR-CLIP
- (2011) Manuel Ascano et al. Wiley Interdisciplinary Reviews-RNA
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- (2011) David L Corcoran et al. GENOME BIOLOGY
- TargetSpy: a supervised machine learning approach for microRNA target prediction
- (2010) Martin Sturm et al. BMC BIOINFORMATICS
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- (2010) Peter T. Nelson et al. BRAIN RESEARCH
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- (2010) Markus Hafner et al. CELL
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- (2010) Lars Dölken et al. Cell Host & Microbe
- MicroRNAs Both Promote and Antagonize Longevity in C. elegans
- (2010) Alexandre de Lencastre et al. CURRENT BIOLOGY
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- Got target?: computational methods for microRNA target prediction and their extension
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- Systematic Proteome Analysis Identifies Transcription Factor YY1 as a Direct Target of miR-34a
- (2010) Qing-Rong Chen et al. JOURNAL OF PROTEOME RESEARCH
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- (2010) Yi Yang et al. Molecular BioSystems
- Expanding the MicroRNA Targeting Code: Functional Sites with Centered Pairing
- (2010) Chanseok Shin et al. MOLECULAR CELL
- Pathogenic LRRK2 negatively regulates microRNA-mediated translational repression
- (2010) Stephan Gehrke et al. NATURE
- A dicer-independent miRNA biogenesis pathway that requires Ago catalysis
- (2010) Sihem Cheloufi et al. NATURE
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- (2010) Huili Guo et al. NATURE
- A coding-independent function of gene and pseudogene mRNAs regulates tumour biology
- (2010) Laura Poliseno et al. NATURE
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- (2010) Martijn Kedde et al. NATURE CELL BIOLOGY
- A quantitative targeted proteomics approach to validate predicted microRNA targets in C. elegans
- (2010) Marko Jovanovic et al. NATURE METHODS
- The widespread regulation of microRNA biogenesis, function and decay
- (2010) Jacek Krol et al. NATURE REVIEWS GENETICS
- Comprehensive discovery of endogenous Argonaute binding sites in Caenorhabditis elegans
- (2010) Dimitrios G Zisoulis et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
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- (2010) Julian König et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Desperately seeking microRNA targets
- (2010) Marshall Thomas et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Strategies to identify microRNA targets: New advances
- (2010) Hongtao Jin et al. New Biotechnology
- MicroRNAs – targeting and target prediction
- (2010) Takaya Saito et al. New Biotechnology
- CLIPZ: a database and analysis environment for experimentally determined binding sites of RNA-binding proteins
- (2010) M. Khorshid et al. NUCLEIC ACIDS RESEARCH
- starBase: a database for exploring microRNA–mRNA interaction maps from Argonaute CLIP-Seq and Degradome-Seq data
- (2010) Jian-Hua Yang et al. NUCLEIC ACIDS RESEARCH
- Affinity purification of microRNA-133a with the cardiac transcription factor, Hand2
- (2010) N. K. Vo et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Transcriptome and targetome analysis in MIR155 expressing cells using RNA-seq
- (2010) G. Xu et al. RNA
- MicroRNA sponges: Progress and possibilities
- (2010) M. S. Ebert et al. RNA
- A Novel miRNA Processing Pathway Independent of Dicer Requires Argonaute2 Catalytic Activity
- (2010) D. Cifuentes et al. SCIENCE
- Computational methods to identify miRNA targets
- (2010) Molly Hammell SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY
- A study of miRNAs targets prediction and experimental validation
- (2010) Yong Huang et al. Protein & Cell
- HITS-CLIP: panoramic views of protein-RNA regulation in living cells
- (2010) Robert B. Darnell Wiley Interdisciplinary Reviews-RNA
- Comprehensive modeling of microRNA targets predicts functional non-conserved and non-canonical sites
- (2010) Doron Betel et al. GENOME BIOLOGY
- TargetMiner: microRNA target prediction with systematic identification of tissue-specific negative examples
- (2009) Sanghamitra Bandyopadhyay et al. BIOINFORMATICS
- nhl-2 Modulates MicroRNA Activity in Caenorhabditis elegans
- (2009) Christopher M. Hammell et al. CELL
- The TRIM-NHL Protein TRIM32 Activates MicroRNAs and Prevents Self-Renewal in Mouse Neural Progenitors
- (2009) Jens C. Schwamborn et al. CELL
- MicroRNAs: Target Recognition and Regulatory Functions
- (2009) David P. Bartel CELL
- Widespread Shortening of 3′UTRs by Alternative Cleavage and Polyadenylation Activates Oncogenes in Cancer Cells
- (2009) Christine Mayr et al. CELL
- Survey of Computational Algorithms for MicroRNA Target Prediction
- (2009) Dong Yue et al. CURRENT GENOMICS
- Systematic analysis of dynamic miRNA-target interactions during C. elegans development
- (2009) L. Zhang et al. DEVELOPMENT
- miR-9a prevents apoptosis during wing development by repressing Drosophila LIM-only
- (2009) Fernando Bejarano et al. DEVELOPMENTAL BIOLOGY
- Experimental identification of microRNA targets
- (2009) Ulf Andersson Ørom et al. GENE
- HuR recruits let-7/RISC to repress c-Myc expression
- (2009) H. H. Kim et al. GENES & DEVELOPMENT
- An Integrated Approach for Experimental Target Identification of Hypoxia-induced miR-210
- (2009) Pasquale Fasanaro et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Computational approaches for microRNA studies: a review
- (2009) Li Li et al. MAMMALIAN GENOME
- Quantitative Proteomic Profiling of Prostate Cancer Reveals a Role for miR-128 in Prostate Cancer
- (2009) Amjad P. Khan et al. MOLECULAR & CELLULAR PROTEOMICS
- Mammalian miRNA RISC Recruits CAF1 and PABP to Affect PABP-Dependent Deadenylation
- (2009) Marc R. Fabian et al. MOLECULAR CELL
- Argonaute HITS-CLIP decodes microRNA–mRNA interaction maps
- (2009) Sung Wook Chi et al. NATURE
- Transgenic microRNA inhibition with spatiotemporal specificity in intact organisms
- (2009) Carlos M Loya et al. NATURE METHODS
- Predicting microRNA targets and functions: traps for the unwary
- (2009) William Ritchie et al. NATURE METHODS
- Biogenesis of small RNAs in animals
- (2009) V. Narry Kim et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Current tools for the identification of miRNA genes and their targets
- (2009) N. D. Mendes et al. NUCLEIC ACIDS RESEARCH
- DIANA-microT web server: elucidating microRNA functions through target prediction
- (2009) M. Maragkakis et al. NUCLEIC ACIDS RESEARCH
- Labeled microRNA pull-down assay system: an experimental approach for high-throughput identification of microRNA-target mRNAs
- (2009) Ren-Jun Hsu et al. NUCLEIC ACIDS RESEARCH
- Sequence context outside the target region influences the effectiveness of miR-223 target sites in the RhoB 3′UTR
- (2009) Guihua Sun et al. NUCLEIC ACIDS RESEARCH
- Tandem affinity purification of miRNA target mRNAs (TAP-Tar)
- (2009) Nora Nonne et al. NUCLEIC ACIDS RESEARCH
- Vectors expressing efficient RNA decoys achieve the long-term suppression of specific microRNA activity in mammalian cells
- (2009) Takeshi Haraguchi et al. NUCLEIC ACIDS RESEARCH
- Immunopurification of Ago1 miRNPs selects for a distinct class of microRNA targets
- (2009) X. Hong et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Identification of miR-21 targets in breast cancer cells using a quantitative proteomic approach
- (2009) Yi Yang et al. PROTEOMICS
- Anti-Argonaute RIP-Chip shows that miRNA transfections alter global patterns of mRNA recruitment to microribonucleoprotein complexes
- (2009) W.-X. Wang et al. RNA
- Poly(A)-binding protein modulates mRNA susceptibility to cap-dependent miRNA-mediated repression
- (2009) R. W. Walters et al. RNA
- Therapeutic Silencing of MicroRNA-122 in Primates with Chronic Hepatitis C Virus Infection
- (2009) R. E. Lanford et al. SCIENCE
- Concordant Regulation of Translation and mRNA Abundance for Hundreds of Targets of a Human microRNA
- (2009) David G. Hendrickson et al. PLOS BIOLOGY
- Identification of genes targeted by microRNAs
- (2008) Tamas Dalmay BIOCHEMICAL SOCIETY TRANSACTIONS
- MicroRNA target prediction by expression analysis of host genes
- (2008) V. A. Gennarino et al. GENOME RESEARCH
- MicroRNA-target pairs in the rat kidney identified by microRNA microarray, proteomic, and bioinformatic analysis
- (2008) Z. Tian et al. GENOME RESEARCH
- Most mammalian mRNAs are conserved targets of microRNAs
- (2008) R. C. Friedman et al. GENOME RESEARCH
- Selected reaction monitoring for quantitative proteomics: a tutorial
- (2008) Vinzenz Lange et al. Molecular Systems Biology
- The impact of microRNAs on protein output
- (2008) Daehyun Baek et al. NATURE
- Widespread changes in protein synthesis induced by microRNAs
- (2008) Matthias Selbach et al. NATURE
- HITS-CLIP yields genome-wide insights into brain alternative RNA processing
- (2008) Donny D. Licatalosi et al. NATURE
- LNA-mediated microRNA silencing in non-human primates
- (2008) Joacim Elmén et al. NATURE
- Exploiting position effects and the gypsy retrovirus insulator to engineer precisely expressed transgenes
- (2008) Michele Markstein et al. NATURE GENETICS
- Stable knockdown of microRNA in vivo by lentiviral vectors
- (2008) Bernhard Gentner et al. NATURE METHODS
- miRecords: an integrated resource for microRNA-target interactions
- (2008) F. Xiao et al. NUCLEIC ACIDS RESEARCH
- Systematic Identification of mRNAs Recruited to Argonaute 2 by Specific microRNAs and Corresponding Changes in Transcript Abundance
- (2008) David G. Hendrickson et al. PLoS One
- Integrative MicroRNA and Proteomic Approaches Identify Novel Osteoarthritis Genes and Their Collaborative Metabolic and Inflammatory Networks
- (2008) Dimitrios Iliopoulos et al. PLoS One
- A novel biochemical method to identify target genes of individual microRNAs: Identification of a new Caenorhabditis elegans let-7 target
- (2008) Y. Andachi RNA
- Deadenylation is a widespread effect of miRNA regulation
- (2008) A. Eulalio et al. RNA
- Hybrid Neurons in a MicroRNA Mutant Are Putative Evolutionary Intermediates in Insect CO2 Sensory Systems
- (2008) P. Cayirlioglu et al. SCIENCE
- Experimental validation of miRNA targets
- (2007) Donald E. Kuhn et al. METHODS
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