Next-generation active immunization approach for synucleinopathies: implications for Parkinson’s disease clinical trials
Published 2014 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Next-generation active immunization approach for synucleinopathies: implications for Parkinson’s disease clinical trials
Authors
Keywords
Vaccination, Parkinson’s disease, Immunotherapy, Alpha-synuclein, AFFITOPE<sup><strong class=EmphasisTypeBold >®</strong></sup>, AFFITOME<sup>®</sup>
Journal
ACTA NEUROPATHOLOGICA
Volume 127, Issue 6, Pages 861-879
Publisher
Springer Nature
Online
2014-02-13
DOI
10.1007/s00401-014-1256-4
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Axonopathy in an α-Synuclein Transgenic Model of Lewy Body Disease Is Associated with Extensive Accumulation of C-Terminal–Truncated α-Synuclein
- (2013) Dora Games et al. AMERICAN JOURNAL OF PATHOLOGY
- Time course and progression of wild type α-Synuclein accumulation in a transgenic mouse model
- (2013) David Amschl et al. BMC NEUROSCIENCE
- Incidence and Pathology of Synucleinopathies and Tauopathies Related to Parkinsonism
- (2013) Rodolfo Savica et al. JAMA Neurology
- Targeting Phospho-Ser422 by Active Tau Immunotherapy in the THYTau22 Mouse Model: A Suitable Therapeutic Approach
- (2012) Nadege Zommer et al. Current Alzheimer Research
- Fluoxetine ameliorates behavioral and neuropathological deficits in a transgenic model mouse of α-synucleinopathy
- (2012) Kiren Ubhi et al. EXPERIMENTAL NEUROLOGY
- Trans-cellular Propagation of Tau Aggregation by Fibrillar Species
- (2012) Najla Kfoury et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Antibody-Aided Clearance of Extracellular -Synuclein Prevents Cell-to-Cell Aggregate Transmission
- (2012) E.-J. Bae et al. JOURNAL OF NEUROSCIENCE
- The many faces of α-synuclein: from structure and toxicity to therapeutic target
- (2012) Hilal A. Lashuel et al. NATURE REVIEWS NEUROSCIENCE
- Alpha-synuclein overexpressing transgenic mice show internal organ pathology and autonomic deficits
- (2012) Penelope J. Hallett et al. NEUROBIOLOGY OF DISEASE
- Propagation of Tau Pathology in a Model of Early Alzheimer's Disease
- (2012) Alix de Calignon et al. NEURON
- A Progressive Mouse Model of Parkinson’s Disease: The Thy1-aSyn (“Line 61”) Mice
- (2012) Marie-Francoise Chesselet et al. Neurotherapeutics
- Trans-Synaptic Spread of Tau Pathology In Vivo
- (2012) Li Liu et al. PLoS One
- Immunotherapy for Alzheimer's Disease: Rational Basis in Ongoing Clinical Trials
- (2011) Manuel Menendez-Gonzalez et al. CURRENT PHARMACEUTICAL DESIGN
- AFFITOME® technology in neurodegenerative diseases: The doubling advantage
- (2011) Achim Schneeberger et al. Human vaccines & immunotherapeutics
- Protein aggregate spreading in neurodegenerative diseases: Problems and perspectives
- (2011) Seung-Jae Lee et al. NEUROSCIENCE RESEARCH
- Vaccination for Parkinson's disease
- (2011) A. Schneeberger et al. PARKINSONISM & RELATED DISORDERS
- Passive Immunization Reduces Behavioral and Neuropathological Deficits in an Alpha-Synuclein Transgenic Model of Lewy Body Disease
- (2011) Eliezer Masliah et al. PLoS One
- In vivo demonstration that -synuclein oligomers are toxic
- (2011) B. Winner et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Inflammation in neurodegenerative diseases
- (2010) Sandra Amor et al. IMMUNOLOGY
- Interactions between Chemokines
- (2010) Anna Cook et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Direct Transfer of α-Synuclein from Neuron to Astroglia Causes Inflammatory Responses in Synucleinopathies
- (2010) He-Jin Lee et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Neurodegeneration in a Transgenic Mouse Model of Multiple System Atrophy Is Associated with Altered Expression of Oligodendroglial-Derived Neurotrophic Factors
- (2010) K. Ubhi et al. JOURNAL OF NEUROSCIENCE
- A Pathologic Cascade Leading to Synaptic Dysfunction in -Synuclein-Induced Neurodegeneration
- (2010) D. A. Scott et al. JOURNAL OF NEUROSCIENCE
- Selective Molecular Alterations in the Autophagy Pathway in Patients with Lewy Body Disease and in Models of α-Synucleinopathy
- (2010) Leslie Crews et al. PLoS One
- Chemokines and Chemokine Receptors: Standing at the Crossroads of Immunobiology and Neurobiology
- (2009) Richard M. Ransohoff IMMUNITY
- Vaccination with A -Displaying Virus-Like Particles Reduces Soluble and Insoluble Cerebral A and Lowers Plaque Burden in APP Transgenic Mice
- (2009) P. Bach et al. JOURNAL OF IMMUNOLOGY
- Beclin 1 Gene Transfer Activates Autophagy and Ameliorates the Neurodegenerative Pathology in -Synuclein Models of Parkinson's and Lewy Body Diseases
- (2009) B. Spencer et al. JOURNAL OF NEUROSCIENCE
- Does neuroinflammation fan the flame in neurodegenerative diseases?
- (2009) Tamy C Frank-Cannon et al. Molecular Neurodegeneration
- Dissecting the potential molecular mechanisms underlying α-synuclein cell-to-cell transfer in Parkinson's disease
- (2009) Elodie Angot et al. PARKINSONISM & RELATED DISORDERS
- Inclusion formation and neuronal cell death through neuron-to-neuron transmission of -synuclein
- (2009) P. Desplats et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Is Parkinson's disease a prion disorder?
- (2009) C. W. Olanow et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Exploratory activity and motor coordination in old versus middle-aged C57BL/6J mice
- (2008) R. Lalonde et al. ARCHIVES OF GERONTOLOGY AND GERIATRICS
- Clearance and deposition of extracellular α-synuclein aggregates in microglia
- (2008) He-Jin Lee et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Role of Nitric Oxide Synthases in Parkinson’s Disease: A Review on the Antioxidant and Anti-inflammatory Activity of Polyphenols
- (2008) Katia Aquilano et al. NEUROCHEMICAL RESEARCH
Publish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn MoreCreate your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create Now