Genome-wide association meta-analysis of human longevity identifies a novel locus conferring survival beyond 90 years of age
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Title
Genome-wide association meta-analysis of human longevity identifies a novel locus conferring survival beyond 90 years of age
Authors
Keywords
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Journal
HUMAN MOLECULAR GENETICS
Volume 23, Issue 16, Pages 4420-4432
Publisher
Oxford University Press (OUP)
Online
2014-04-01
DOI
10.1093/hmg/ddu139
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Note: Only part of the references are listed.- Health and function of participants in the Long Life Family Study: A comparison with other cohorts
- (2016) Anne B. Newman et al. Aging-US
- Identifying the genomic determinants of aging and longevity in human population studies: Progress and challenges
- (2013) Joris Deelen et al. BIOESSAYS
- Genetic determinants of mortality. Can findings from genome-wide association studies explain variation in human mortality?
- (2013) Andrea Ganna et al. HUMAN GENETICS
- Systematic identification of trans eQTLs as putative drivers of known disease associations
- (2013) Harm-Jan Westra et al. NATURE GENETICS
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- (2012) A. P. Boyle et al. GENOME RESEARCH
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- (2012) LANCET
- Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes
- (2012) NATURE GENETICS
- A genome-wide approach accounting for body mass index identifies genetic variants influencing fasting glycemic traits and insulin resistance
- (2012) Alisa K Manning et al. NATURE GENETICS
- Genetic Signatures of Exceptional Longevity in Humans
- (2012) Paola Sebastiani et al. PLoS One
- Genome-wide association study identifies a single major locus contributing to survival into old age; the APOE locus revisited
- (2011) Joris Deelen et al. AGING CELL
- Genome-Wide Association Identifies Nine Common Variants Associated With Fasting Proinsulin Levels and Provides New Insights Into the Pathophysiology of Type 2 Diabetes
- (2011) R. J. Strawbridge et al. DIABETES
- How to deal with the early GWAS data when imputing and combining different arrays is necessary
- (2011) Hae-Won Uh et al. EUROPEAN JOURNAL OF HUMAN GENETICS
- A genome-wide association study confirms APOE as the major gene influencing survival in long-lived individuals
- (2011) Almut Nebel et al. MECHANISMS OF AGEING AND DEVELOPMENT
- Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk
- (2011) Georg B. Ehret et al. NATURE
- Common variants at MS4A4/MS4A6E, CD2AP, CD33 and EPHA1 are associated with late-onset Alzheimer's disease
- (2011) Adam C Naj et al. NATURE GENETICS
- Common variants at ABCA7, MS4A6A/MS4A4E, EPHA1, CD33 and CD2AP are associated with Alzheimer's disease
- (2011) Paul Hollingworth et al. NATURE GENETICS
- Large-scale association analysis identifies 13 new susceptibility loci for coronary artery disease
- (2011) Heribert Schunkert et al. NATURE GENETICS
- Genome-wide association study identifies six new loci influencing pulse pressure and mean arterial pressure
- (2011) Louise V Wain et al. NATURE GENETICS
- Non-coding RNAs in human disease
- (2011) Manel Esteller NATURE REVIEWS GENETICS
- HaploReg: a resource for exploring chromatin states, conservation, and regulatory motif alterations within sets of genetically linked variants
- (2011) L. D. Ward et al. NUCLEIC ACIDS RESEARCH
- Speed-bumps ahead for the genetics of later-life diseases
- (2011) Thomas B.L. Kirkwood et al. TRENDS IN GENETICS
- Familial longevity is marked by enhanced insulin sensitivity
- (2010) Carolien A. Wijsman et al. AGING CELL
- LocusZoom: regional visualization of genome-wide association scan results
- (2010) R. J. Pruim et al. BIOINFORMATICS
- Genevar: a database and Java application for the analysis and visualization of SNP-gene associations in eQTL studies
- (2010) T.-P. Yang et al. BIOINFORMATICS
- Common Variants at 10 Genomic Loci Influence Hemoglobin A1C Levels via Glycemic and Nonglycemic Pathways
- (2010) N. Soranzo et al. DIABETES
- Hallmark Features of Immunosenescence Are Absent in Familial Longevity
- (2010) E. Derhovanessian et al. JOURNAL OF IMMUNOLOGY
- A Meta-analysis of Four Genome-Wide Association Studies of Survival to Age 90 Years or Older: The Cohorts for Heart and Aging Research in Genomic Epidemiology Consortium
- (2010) Anne B. Newman et al. JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES
- Biological, clinical and population relevance of 95 loci for blood lipids
- (2010) Tanya M. Teslovich et al. NATURE
- Genetic variation in GIPR influences the glucose and insulin responses to an oral glucose challenge
- (2010) Richa Saxena et al. NATURE GENETICS
- New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk
- (2010) Josée Dupuis et al. NATURE GENETICS
- Genomics of human longevity
- (2010) P. E. Slagboom et al. PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES
- Genetics and Beyond – The Transcriptome of Human Monocytes and Disease Susceptibility
- (2010) Tanja Zeller et al. PLoS One
- Genome-wide association study (GWAS)-identified disease risk alleles do not compromise human longevity
- (2010) M. Beekman et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Common Inherited Variation in Mitochondrial Genes Is Not Enriched for Associations with Type 2 Diabetes or Related Glycemic Traits
- (2010) Ayellet V. Segrè et al. PLoS Genetics
- Nonagenarian Siblings and Their Offspring Display Lower Risk of Mortality and Morbidity than Sporadic Nonagenarians: The Leiden Longevity Study
- (2009) Rudi G.J. Westendorp et al. JOURNAL OF THE AMERICAN GERIATRICS SOCIETY
- Long non-coding RNAs: insights into functions
- (2009) Tim R. Mercer et al. NATURE REVIEWS GENETICS
- Association ofFOXO3Avariation with human longevity confirmed in German centenarians
- (2009) Friederike Flachsbart et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Identifying Relationships among Genomic Disease Regions: Predicting Genes at Pathogenic SNP Associations and Rare Deletions
- (2009) Soumya Raychaudhuri et al. PLoS Genetics
- Estimation of the multiple testing burden for genomewide association studies of nearly all common variants
- (2008) Itsik Pe'er et al. GENETIC EPIDEMIOLOGY
- Lower Systolic Blood Pressure Is Associated with Greater Mortality in People Aged 85 and Older
- (2008) Lena Molander et al. JOURNAL OF THE AMERICAN GERIATRICS SOCIETY
- Inequalities in healthy life years in the 25 countries of the European Union in 2005: a cross-national meta-regression analysis
- (2008) Carol Jagger et al. LANCET
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