Viral factors in influenza pandemic risk assessment

Differences in the epidemiology and virology of mild, severe and fatal human infections with avian influenza A (H7N9) virus

(2016) Jianping Sha et al.   ARCHIVES OF VIROLOGY

Modulation of the pH Stability of Influenza Virus Hemagglutinin: A Host Cell Adaptation Strategy

(2016) Santiago Di Lella et al.   BIOPHYSICAL JOURNAL

Coupling high-throughput genetics with phylogenetic information reveals an epistatic interaction on the influenza A virus M segment

(2016) Nicholas C. Wu et al.   BMC GENOMICS

Selective Bottlenecks Shape Evolutionary Pathways Taken during Mammalian Adaptation of a 1918-like Avian Influenza Virus

(2016) Louise H. Moncla et al.   Cell Host & Microbe

Clinical, epidemiological and virological characteristics of the first detected human case of avian influenza A(H5N6) virus

(2016) Rusheng Zhang et al.   INFECTION GENETICS AND EVOLUTION

Ongoing transmission of avian influenza A viruses in Hong Kong despite very comprehensive poultry control measures: A prospective seroepidemiology study

(2016) Kelvin K.W. To et al.   JOURNAL OF INFECTION

Amino Acid Substitutions That Affect Receptor Binding and Stability of the Hemagglutinin of Influenza A/H7N9 Virus

(2016) Eefje J. A. Schrauwen et al.   JOURNAL OF VIROLOGY

Complexities in Ferret Influenza Virus Pathogenesis and Transmission Models

(2016) Jessica A. Belser et al.   MICROBIOLOGY AND MOLECULAR BIOLOGY REVIEWS

Species difference in ANP32A underlies influenza A virus polymerase host restriction

(2016) Jason S. Long et al.   NATURE

Quantifying influenza virus diversity and transmission in humans

(2016) Leo L M Poon et al.   NATURE GENETICS

Molecular requirements for a pandemic influenza virus: An acid-stable hemagglutinin protein

(2016) Marion Russier et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The global antigenic diversity of swine influenza A viruses

(2016) Nicola S Lewis et al.   eLife

Novel Highly Pathogenic Avian A(H5N2) and A(H5N8) Influenza Viruses of Clade 2.3.4.4 from North America Have Limited Capacity for Replication and Transmission in Mammals

(2016) Bryan S. Kaplan et al.   mSphere

Avian influenza viruses in humans

(2016) J.S. MALIK PEIRIS   REVUE SCIENTIFIQUE ET TECHNIQUE-OFFICE INTERNATIONAL DES EPIZOOTIES

Software for the analysis and visualization of deep mutational scanning data

(2015) Jesse D Bloom   BMC BIOINFORMATICS

Differences in the Epidemiology of Human Cases of Avian Influenza A(H7N9) and A(H5N1) Viruses Infection

(2015) Ying Qin et al.   CLINICAL INFECTIOUS DISEASES

Serological comparison of antibodies to avian influenza viruses, subtypes H5N2, H6N1, H7N3 and H7N9 between poultry workers and non-poultry workers in Taiwan in 2012

(2015) S. Y. HUANG et al.   EPIDEMIOLOGY AND INFECTION

Adaptive mutation PB2 D701N promotes nuclear import of influenza vRNPs in mammalian cells

(2015) Hanna Sediri et al.   EUROPEAN JOURNAL OF CELL BIOLOGY

Nomenclature updates resulting from the evolution of avian influenza A(H5) virus clades 2.1.3.2a, 2.2.1, and 2.3.4 during 2013-2014

(2015) Gavin J. D. Smith et al.   Influenza and Other Respiratory Viruses

Two novel reassortants of avian influenza A (H5N6) virus in China

(2015) Yuhai Bi et al.   JOURNAL OF GENERAL VIROLOGY

Identification of Stabilizing Mutations in an H5 Hemagglutinin Influenza Virus Protein

(2015) Anthony Hanson et al.   JOURNAL OF VIROLOGY

Continual Reintroduction of Human Pandemic H1N1 Influenza A Viruses into Swine in the United States, 2009 to 2014

(2015) Martha I. Nelson et al.   JOURNAL OF VIROLOGY

Pandemic Swine H1N1 Influenza Viruses with Almost Undetectable Neuraminidase Activity Are Not Transmitted via Aerosols in Ferrets and Are Inhibited by Human Mucus but Not Swine Mucus

(2015) Mark Zanin et al.   JOURNAL OF VIROLOGY

The soft palate is an important site of adaptation for transmissible influenza viruses

(2015) Seema S. Lakdawala et al.   NATURE

End of cancer-genome project prompts rethink

(2015) Heidi Ledford   NATURE

Human Infection with a Novel Avian Influenza A(H5N6) Virus

(2015) Zi-Feng Yang et al.   NEW ENGLAND JOURNAL OF MEDICINE

Immune history profoundly affects broadly protective B cell responses to influenza

(2015) Sarah F. Andrews et al.   Science Translational Medicine

An H10N8 influenza virus vaccine strain and mouse challenge model based on the human isolate A/Jiangxi-Donghu/346/13

(2015) Teddy John Wohlbold et al.   VACCINE

Novel reassortant H5N5 viruses bind to a human-type receptor as a factor in pandemic risk

(2015) Qunhui Li et al.   VETERINARY MICROBIOLOGY

Viral dominance of reassortants between canine influenza H3N2 and pandemic (2009) H1N1 viruses from a naturally co-infected dog

(2015) Woonsung Na et al.   Virology Journal

Reply to “Studies on Influenza Virus Transmission between Ferrets: the Public Health Risks Revisited”

(2015) Marc Lipsitch et al.   mBio

Studies on Influenza Virus Transmission between Ferrets: the Public Health Risks Revisited

(2015) Ron A. M. Fouchier   mBio

Mammalian adaptation of influenza A(H7N9) virus is limited by a narrow genetic bottleneck

(2015) Hassan Zaraket et al.   Nature Communications

Seven challenges in modeling pathogen dynamics within-host and across scales

(2015) Julia R. Gog et al.   Epidemics

Nine challenges in modelling the emergence of novel pathogens

(2015) James O. Lloyd-Smith et al.   Epidemics

Geometric Constraints Dominate the Antigenic Evolution of Influenza H3N2 Hemagglutinin

(2015) Austin G. Meyer et al.   PLoS Pathogens

Mapping influenza transmission in the ferret model to transmission in humans

(2015) Michael G Buhnerkempe et al.   eLife

Modelling the species jump: towards assessing the risk of human infection from novel avian influenzas

(2015) A. A. Hill et al.   Royal Society Open Science

GRASP: analysis of genotype-phenotype results from 1390 genome-wide association studies and corresponding open access database

(2014) R. Leslie et al.   BIOINFORMATICS

YASARA View—molecular graphics for all devices—from smartphones to workstations

(2014) Elmar Krieger et al.   BIOINFORMATICS

Identification, Characterization, and Natural Selection of Mutations Driving Airborne Transmission of A/H5N1 Virus

(2014) Martin Linster et al.   CELL

Influenza A Virus Transmission Bottlenecks Are Defined by Infection Route and Recipient Host

(2014) Andrew Varble et al.   Cell Host & Microbe

A LC3-Interacting Motif in the Influenza A Virus M2 Protein Is Required to Subvert Autophagy and Maintain Virion Stability

(2014) Rupert Beale et al.   Cell Host & Microbe

Seroprevalence to Avian Influenza A(H7N9) Virus Among Poultry Workers and the General Population in Southern China: A Longitudinal Study

(2014) Xin Wang et al.   CLINICAL INFECTIOUS DISEASES

Glycomic Characterization of Respiratory Tract Tissues of Ferrets

(2014) Nan Jia et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Viral determinants of influenza A virus host range

(2014) A. V. Cauldwell et al.   JOURNAL OF GENERAL VIROLOGY

Avian Influenza A(H5N1) and A(H9N2) Seroprevalence and Risk Factors for Infection Among Egyptians: A Prospective, Controlled Seroepidemiological Study

(2014) Mokhtar R. Gomaa et al.   JOURNAL OF INFECTIOUS DISEASES

How sticky should a virus be? The impact of virus binding and release on transmission fitness using influenza as an example

(2014) A. Handel et al.   Journal of the Royal Society Interface

Introductions and Evolution of Human-Origin Seasonal Influenza A Viruses in Multinational Swine Populations

(2014) M. I. Nelson et al.   JOURNAL OF VIROLOGY

The Matrix Gene Segment Destabilizes the Acid and Thermal Stability of the Hemagglutinin of Pandemic Live Attenuated Influenza Virus Vaccines

(2014) C. D. O'Donnell et al.   JOURNAL OF VIROLOGY

The M Segment of the 2009 Pandemic Influenza Virus Confers Increased Neuraminidase Activity, Filamentous Morphology, and Efficient Contact Transmissibility to A/Puerto Rico/8/1934-Based Reassortant Viruses

(2014) P. J. Campbell et al.   JOURNAL OF VIROLOGY

Clinical and epidemiological characteristics of a fatal case of avian influenza A H10N8 virus infection: a descriptive study

(2014) HaiYing Chen et al.   LANCET

Structural insight into cap-snatching and RNA synthesis by influenza polymerase

(2014) Stefan Reich et al.   NATURE

The draft genome sequence of the ferret (Mustela putorius furo) facilitates study of human respiratory disease

(2014) Xinxia Peng et al.   NATURE BIOTECHNOLOGY

Deep mutational scanning: a new style of protein science

(2014) Douglas M Fowler et al.   NATURE METHODS

Filament-Producing Mutants of Influenza A/Puerto Rico/8/1934 (H1N1) Virus Have Higher Neuraminidase Activities than the Spherical Wild-Type

(2014) Jill Seladi-Schulman et al.   PLoS One

Genesis and pathogenesis of the 1918 pandemic H1N1 influenza A virus

(2014) M. Worobey et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Glycan receptor specificity as a useful tool for characterization and surveillance of influenza A virus

(2014) Rahul Raman et al.   TRENDS IN MICROBIOLOGY

Use of Highly Pathogenic Avian Influenza A(H5N1) Gain-Of-Function Studies for Molecular-Based Surveillance and Pandemic Preparedness: FIG 1 

(2014) C. Todd Davis et al.   mBio

Influenza Gain-of-Function Experiments: Their Role in Vaccine Virus Recommendation and Pandemic Preparedness

(2014) S. Schultz-Cherry et al.   mBio

Moratorium on Research Intended To Create Novel Potential Pandemic Pathogens: FIG 1 

(2014) Marc Lipsitch et al.   mBio

Predicting the risk of avian influenza A H7N9 infection in live-poultry markets across Asia

(2014) Marius Gilbert et al.   Nature Communications

Ferrets exclusively synthesize Neu5Ac and express naturally humanized influenza A virus receptors

(2014) Preston S.K. Ng et al.   Nature Communications

Epistatically Interacting Substitutions Are Enriched during Adaptive Protein Evolution

(2014) Lizhi Ian Gong et al.   PLoS Genetics

Genetics, Receptor Binding Property, and Transmissibility in Mammals of Naturally Isolated H9N2 Avian Influenza Viruses

(2014) Xuyong Li et al.   PLoS Pathogens

A Single Amino Acid in the Stalk Region of the H1N1pdm Influenza Virus HA Protein Affects Viral Fusion, Stability and Infectivity

(2014) Christopher R. Cotter et al.   PLoS Pathogens

The inherent mutational tolerance and antigenic evolvability of influenza hemagglutinin

(2014) Bargavi Thyagarajan et al.   eLife

Improving pandemic influenza risk assessment

(2014) Colin A Russell et al.   eLife

Receptor binding and pH stability — How influenza A virus hemagglutinin affects host-specific virus infection

(2013) Caroline M. Mair et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Containing the accidental laboratory escape of potential pandemic influenza viruses

(2013) Stefano Merler et al.   BMC Medicine

Structural Determinants for Naturally Evolving H5N1 Hemagglutinin to Switch Its Receptor Specificity

(2013) Kannan Tharakaraman et al.   CELL

Outbreak of Variant Influenza A(H3N2) Virus in the United States

(2013) M. A. Jhung et al.   CLINICAL INFECTIOUS DISEASES

Considerations regarding appropriate sample size for conducting ferret transmission experiments

(2013) Jessica A Belser et al.   Future Microbiology

Mutations in haemagglutinin that affect receptor binding and pH stability increase replication of a PR8 influenza virus with H5 HA in the upper respiratory tract of ferrets and may contribute to transmissibility

(2013) H. Shelton et al.   JOURNAL OF GENERAL VIROLOGY

The Effect of the PB2 Mutation 627K on Highly Pathogenic H5N1 Avian Influenza Virus Is Dependent on the Virus Lineage

(2013) J. S. Long et al.   JOURNAL OF VIROLOGY

Hemagglutinin Receptor Specificity and Structural Analyses of Respiratory Droplet-Transmissible H5N1 Viruses

(2013) R. P. de Vries et al.   JOURNAL OF VIROLOGY

The Short Stalk Length of Highly Pathogenic Avian Influenza H5N1 Virus Neuraminidase Limits Transmission of Pandemic H1N1 Virus in Ferrets

(2013) D. Blumenkrantz et al.   JOURNAL OF VIROLOGY

Spherical Influenza Viruses Have a Fitness Advantage in Embryonated Eggs, while Filament-Producing Strains Are Selected In Vivo

(2013) J. Seladi-Schulman et al.   JOURNAL OF VIROLOGY

The pH of Activation of the Hemagglutinin Protein Regulates H5N1 Influenza Virus Replication and Pathogenesis in Mice

(2013) H. Zaraket et al.   JOURNAL OF VIROLOGY

Molecular Basis of the Receptor Binding Specificity Switch of the Hemagglutinins from both the 1918 and 2009 Pandemic Influenza A Viruses by a D225G Substitution

(2013) W. Zhang et al.   JOURNAL OF VIROLOGY

Increased Acid Stability of the Hemagglutinin Protein Enhances H5N1 Influenza Virus Growth in the Upper Respiratory Tract but Is Insufficient for Transmission in Ferrets

(2013) H. Zaraket et al.   JOURNAL OF VIROLOGY

Emergence of the Virulence-Associated PB2 E627K Substitution in a Fatal Human Case of Highly Pathogenic Avian Influenza Virus A(H7N7) Infection as Determined by Illumina Ultra-Deep Sequencing

(2013) M. Jonges et al.   JOURNAL OF VIROLOGY

AVIAN INFLUENZA SHEDDING PATTERNS IN WATERFOWL: IMPLICATIONS FOR SURVEILLANCE, ENVIRONMENTAL TRANSMISSION, AND DISEASE SPREAD

(2013) Viviane Hénaux et al.   JOURNAL OF WILDLIFE DISEASES

Receptor binding by a ferret-transmissible H5 avian influenza virus

(2013) Xiaoli Xiong et al.   NATURE

Receptor binding by an H7N9 influenza virus from humans

(2013) Xiaoli Xiong et al.   NATURE

Mutational landscape and significance across 12 major cancer types

(2013) Cyriac Kandoth et al.   NATURE

Human Infection with a Novel Avian-Origin Influenza A (H7N9) Virus

(2013) Rongbao Gao et al.   NEW ENGLAND JOURNAL OF MEDICINE

Cross-species comparison of site-specific evolutionary-rate variation in influenza haemagglutinin

(2013) A. G. Meyer et al.   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Multiple scales of selection influence the evolutionary emergence of novel pathogens

(2013) M. Park et al.   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Sample Size Considerations for One-to-One Animal Transmission Studies of the Influenza A Viruses

(2013) Hiroshi Nishiura et al.   PLoS One

Quantifying the Fitness Advantage of Polymerase Substitutions in Influenza A/H7N9 Viruses during Adaptation to Humans

(2013) Judith M. Fonville et al.   PLoS One

Mutational effects on stability are largely conserved during protein evolution

(2013) O. Ashenberg et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Substitutions Near the Receptor Binding Site Determine Major Antigenic Change During Influenza Virus Evolution

(2013) B. F. Koel et al.   SCIENCE

Rapid emergence of a virulent PB2 E627K variant during adaptation of highly pathogenic avian influenza H7N7 virus to mice

(2013) Rineke MC de Jong et al.   Virology Journal

H5N1 receptor specificity as a factor in pandemic risk

(2013) James C. Paulson et al.   VIRUS RESEARCH

Selection on haemagglutinin imposes a bottleneck during mammalian transmission of reassortant H5N1 influenza viruses

(2013) Peter R. Wilker et al.   Nature Communications

Influenza A Virus Utilizes Suboptimal Splicing to Coordinate the Timing of Infection

(2013) Mark A. Chua et al.   Cell Reports

Global Mortality Estimates for the 2009 Influenza Pandemic from the GLaMOR Project: A Modeling Study

(2013) Lone Simonsen et al.   PLOS MEDICINE

Glycomic Analysis of Human Respiratory Tract Tissues and Correlation with Influenza Virus Infection

(2013) Trevenan Walther et al.   PLoS Pathogens

New World Bats Harbor Diverse Influenza A Viruses

(2013) Suxiang Tong et al.   PLoS Pathogens

Influenza HA Subtypes Demonstrate Divergent Phenotypes for Cleavage Activation and pH of Fusion: Implications for Host Range and Adaptation

(2013) Summer E. Galloway et al.   PLoS Pathogens

Stability-mediated epistasis constrains the evolution of an influenza protein

(2013) Lizhi Ian Gong et al.   eLife

Human infection with avian influenza A H6N1 virus: an epidemiological analysis

(2013) Sung-Hsi Wei et al.   Lancet Respiratory Medicine

Tropism and innate host responses of a novel avian influenza A H7N9 virus: an analysis of ex-vivo and in-vitro cultures of the human respiratory tract

(2013) Michael CW Chan et al.   Lancet Respiratory Medicine

Evidence for avian H9N2 influenza virus infections among rural villagers in Cambodia

(2013) Patrick J. Blair et al.   Journal of Infection and Public Health

The H275Y Neuraminidase Mutation of the Pandemic A/H1N1 Influenza Virus Lengthens the Eclipse Phase and Reduces Viral Output of Infected Cells, Potentially Compromising Fitness in Ferrets

(2012) L. T. Pinilla et al.   JOURNAL OF VIROLOGY

Structure and Receptor Complexes of the Hemagglutinin from a Highly Pathogenic H7N7 Influenza Virus

(2012) Hua Yang et al.   JOURNAL OF VIROLOGY

Detecting Patches of Protein Sites of Influenza A Viruses under Positive Selection

(2012) C. Tusche et al.   MOLECULAR BIOLOGY AND EVOLUTION

Experimental adaptation of an influenza H5 HA confers respiratory droplet transmission to a reassortant H5 HA/H1N1 virus in ferrets

(2012) Masaki Imai et al.   NATURE

Flu surveillance lacking

(2012) Declan Butler   NATURE

Decoding the Distribution of Glycan Receptors for Human-Adapted Influenza A Viruses in Ferret Respiratory Tract

(2012) Akila Jayaraman et al.   PLoS One

Evolution of the receptor binding properties of the influenza A(H3N2) hemagglutinin

(2012) Y. P. Lin et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

H5N1 influenza viruses: Facts, not fear

(2012) P. Palese et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Seroevidence for H5N1 Influenza Infections in Humans: Meta-Analysis

(2012) T. T. Wang et al.   SCIENCE

Comment on "Seroevidence for H5N1 Influenza Infections in Humans: Meta-Analysis"

(2012) M. D. Van Kerkhove et al.   SCIENCE

Airborne Transmission of Influenza A/H5N1 Virus Between Ferrets

(2012) S. Herfst et al.   SCIENCE

The Potential for Respiratory Droplet-Transmissible A/H5N1 Influenza Virus to Evolve in a Mammalian Host

(2012) C. A. Russell et al.   SCIENCE

Influenza Virus-Mediated Membrane Fusion: Determinants of Hemagglutinin Fusogenic Activity and Experimental Approaches for Assessing Virus Fusion

(2012) Brian S. Hamilton et al.   Viruses-Basel

Adaptive mutations in NEP compensate for defective H5N1 RNA replication in cultured human cells

(2012) Benjamin Mänz et al.   Nature Communications

Emerging Roles for the Influenza A Virus Nuclear Export Protein (NEP)

(2012) Duncan Paterson et al.   PLoS Pathogens

Species-Specific Inhibition of RIG-I Ubiquitination and IFN Induction by the Influenza A Virus NS1 Protein

(2012) Ricardo Rajsbaum et al.   PLoS Pathogens

A review of mathematical models of influenza A infections within a host or cell culture: lessons learned and challenges ahead

(2011) Catherine AA Beauchemin et al.   BMC PUBLIC HEALTH

Hallmarks of Cancer: The Next Generation

(2011) Douglas Hanahan et al.   CELL

The accumulation of influenza A virus segment 7 spliced mRNAs is regulated by the NS1 protein

(2011) N. C. Robb et al.   JOURNAL OF GENERAL VIROLOGY

Highly Pathogenic Avian Influenza (H5N1): Pathways of Exposure at the Animal‐Human Interface, a Systematic Review

(2011) Maria D. Van Kerkhove et al.   PLoS One

Assessing the In Vitro Fitness of an Oseltamivir-Resistant Seasonal A/H1N1 Influenza Strain Using a Mathematical Model

(2011) Benjamin P. Holder et al.   PLoS One

Single HA2 Mutation Increases the Infectivity and Immunogenicity of a Live Attenuated H5N1 Intranasal Influenza Vaccine Candidate Lacking NS1

(2011) Brigitte M. Krenn et al.   PLoS One

Correction: Serological Evidence of Subclinical Transmission of the 2009 Pandemic H1N1 Influenza Virus Outside of Mexico

(2011) Day-Yu Chao et al.   PLoS One

Hemagglutinin-neuraminidase balance confers respiratory-droplet transmissibility of the pandemic H1N1 influenza virus in ferrets

(2011) H.-L. Yen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Receptor specificity of subtype H1 influenza A viruses isolated from swine and humans in the United States

(2011) Li-Mei Chen et al.   VIROLOGY

In vitro evolution of H5N1 avian influenza virus toward human-type receptor specificity

(2011) Li-Mei Chen et al.   VIROLOGY

Anticipating the Species Jump: Surveillance for Emerging Viral Threats

(2011) M. L. Flanagan et al.   Zoonoses and Public Health

Networks link antigenic and receptor-binding sites of influenza hemagglutinin: Mechanistic insight into fitter strain propagation

(2011) Venkataramanan Soundararajan et al.   Scientific Reports

Prevalence of Epistasis in the Evolution of Influenza A Surface Proteins

(2011) Sergey Kryazhimskiy et al.   PLoS Genetics

Acid Stability of the Hemagglutinin Protein Regulates H5N1 Influenza Virus Pathogenicity

(2011) Rebecca M. DuBois et al.   PLoS Pathogens

Ecology of avian influenza viruses in a changing world

(2010) Kurt J. Vandegrift et al.   Annals of the New York Academy of Sciences

Avian Influenza Virus Surveillance and Wild Birds: Past and Present

(2010) Scott Krauss et al.   AVIAN DISEASES

The I222V Neuraminidase Mutation Has a Compensatory Role in Replication of an Oseltamivir-Resistant Influenza Virus A/H3N2 E119V Mutant

(2010) P. Simon et al.   JOURNAL OF CLINICAL MICROBIOLOGY

In Vitro Assessment of Attachment Pattern and Replication Efficiency of H5N1 Influenza A Viruses with Altered Receptor Specificity

(2010) S. Chutinimitkul et al.   JOURNAL OF VIROLOGY

Receptor Specificity of Influenza A H3N2 Viruses Isolated in Mammalian Cells and Embryonated Chicken Eggs

(2010) J. Stevens et al.   JOURNAL OF VIROLOGY

Introduction of Virulence Markers in PB2 of Pandemic Swine-Origin Influenza Virus Does Not Result in Enhanced Virulence or Transmission

(2010) S. Herfst et al.   JOURNAL OF VIROLOGY

Evidence for Avian and Human Host Cell Factors That Affect the Activity of Influenza Virus Polymerase

(2010) O. Moncorge et al.   JOURNAL OF VIROLOGY

Point: Hypotheses first

(2010) Robert Weinberg   NATURE

Towards identifying genes underlying ecologically relevant traits in Arabidopsis thaliana

(2010) Joy Bergelson et al.   NATURE REVIEWS GENETICS

Receptor Specificity and Transmission of H2N2 Subtype Viruses Isolated from the Pandemic of 1957

(2010) Claudia Pappas et al.   PLoS One

Permissive Secondary Mutations Enable the Evolution of Influenza Oseltamivir Resistance

(2010) J. D. Bloom et al.   SCIENCE

The PB2-E627K Mutation Attenuates Viruses Containing the 2009 H1N1 Influenza Pandemic Polymerase

(2010) B. W. Jagger et al.   mBio

Structures of Receptor Complexes of a North American H7N2 Influenza Hemagglutinin with a Loop Deletion in the Receptor Binding Site

(2010) Hua Yang et al.   PLoS Pathogens

Biological and Structural Characterization of a Host-Adapting Amino Acid in Influenza Virus

(2010) Shinya Yamada et al.   PLoS Pathogens

Context-Specific Target Definition in Influenza A Virus Hemagglutinin-Glycan Receptor Interactions

(2009) Zachary Shriver et al.   CHEMISTRY & BIOLOGY

NS2/NEP protein regulates transcription and replication of the influenza virus RNA genome

(2009) Nicole C. Robb et al.   JOURNAL OF GENERAL VIROLOGY

Distinct Glycan Topology for Avian and Human Sialopentasaccharide Receptor Analogues upon Binding Different Hemagglutinins: A Molecular Dynamics Perspective

(2009) Dong Xu et al.   JOURNAL OF MOLECULAR BIOLOGY

Combining Molecular Dynamics with Bayesian Analysis To Predict and Evaluate Ligand-Binding Mutations in Influenza Hemagglutinin

(2009) Peter M. Kasson et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Structure, Receptor Binding, and Antigenicity of Influenza Virus Hemagglutinins from the 1957 H2N2 Pandemic

(2009) R. Xu et al.   JOURNAL OF VIROLOGY

Amino Acid Residues in the Fusion Peptide Pocket Regulate the pH of Activation of the H5N1 Influenza Virus Hemagglutinin Protein

(2009) M. L. Reed et al.   JOURNAL OF VIROLOGY

The pH of Activation of the Hemagglutinin Protein Regulates H5N1 Influenza Virus Pathogenicity and Transmissibility in Ducks

(2009) M. L. Reed et al.   JOURNAL OF VIROLOGY

Receptor-binding specificity of pandemic influenza A (H1N1) 2009 virus determined by carbohydrate microarray

(2009) Robert A Childs et al.   NATURE BIOTECHNOLOGY

Enhancement of the Influenza A Hemagglutinin (HA)-Mediated Cell-Cell Fusion and Virus Entry by the Viral Neuraminidase (NA)

(2009) Bin Su et al.   PLoS One

Structures of receptor complexes formed by hemagglutinins from the Asian Influenza pandemic of 1957

(2009) J. Liu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Adaptive strategies of the influenza virus polymerase for replication in humans

(2009) Andrew Mehle et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Host Restriction of Avian Influenza Viruses at the Level of the Ribonucleoproteins

(2008) Nadia Naffakh et al.   Annual Review of Microbiology

Neutralizing antibodies derived from the B cells of 1918 influenza pandemic survivors

(2008) Xiaocong Yu et al.   NATURE

Glycan topology determines human adaptation of avian H5N1 virus hemagglutinin

(2008) Aarthi Chandrasekaran et al.   NATURE BIOTECHNOLOGY

The Host-Dependent Interaction of α-Importins with Influenza PB2 Polymerase Subunit Is Required for Virus RNA Replication

(2008) Patricia Resa-Infante et al.   PLoS One

Contemporary North American influenza H7 viruses possess human receptor specificity: Implications for virus transmissibility

(2008) J. A. Belser et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA