Use of Highly Pathogenic Avian Influenza A(H5N1) Gain-Of-Function Studies for Molecular-Based Surveillance and Pandemic Preparedness: FIG 1 

Revised and updated nomenclature for highly pathogenic avian influenza A (H5N1) viruses

(2014)   Influenza and Other Respiratory Viruses

Serological Responses to an Avian Influenza A/H7N9 Vaccine Mixed at the Point-of-Use With MF59 Adjuvant

(2014) Mark J. Mulligan et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Identification of Molecular Markers Associated with Alteration of Receptor-Binding Specificity in a Novel Genotype of Highly Pathogenic Avian Influenza A(H5N1) Viruses Detected in Cambodia in 2013

(2014) S. Rith et al.   JOURNAL OF VIROLOGY

LABEL: Fast and Accurate Lineage Assignment with Assessment of H5N1 and H9N2 Influenza A Hemagglutinins

(2014) Samuel S. Shepard et al.   PLoS One

The K526R substitution in viral protein PB2 enhances the effects of E627K on influenza virus replication

(2014) Wenjun Song et al.   Nature Communications

Improving pandemic influenza risk assessment

(2014) Colin A Russell et al.   eLife

Pathogenesis and transmission of avian influenza A (H7N9) virus in ferrets and mice

(2013) Jessica A. Belser et al.   NATURE

Human Infection with a Novel Avian-Origin Influenza A (H7N9) Virus

(2013) Rongbao Gao et al.   NEW ENGLAND JOURNAL OF MEDICINE

Corrections and Clarifications

(2013)   SCIENCE

Gain-of-Function Research: Unproven Technique

(2013) A. Mahmoud   SCIENCE

Transmission Studies Resume For Avian Flu

(2013) R. A. M. Fouchier et al.   SCIENCE

Infectivity, Transmission, and Pathology of Human-Isolated H7N9 Influenza Virus in Ferrets and Pigs

(2013) H. Zhu et al.   SCIENCE

Synthetic Generation of Influenza Vaccine Viruses for Rapid Response to Pandemics

(2013) P. R. Dormitzer et al.   Science Translational Medicine

Many ways to make an influenza virus - review of influenza virus reverse genetics methods

(2012) Othmar G. Engelhardt   Influenza and Other Respiratory Viruses

Prediction and prevention of the next pandemic zoonosis

(2012) Stephen S Morse et al.   LANCET

Experimental adaptation of an influenza H5 HA confers respiratory droplet transmission to a reassortant H5 HA/H1N1 virus in ferrets

(2012) Masaki Imai et al.   NATURE

Life Technologies promises $1,000 genome

(2012) Laura DeFrancesco   NATURE BIOTECHNOLOGY

Airborne Transmission of Influenza A/H5N1 Virus Between Ferrets

(2012) S. Herfst et al.   SCIENCE

Mammalian-Transmissible H5N1 Influenza: the Dilemma of Dual-Use Research

(2012) R. G. Webster   mBio

Ferret-Transmissible Influenza A(H5N1) Virus: Let Us Err on the Side of Caution

(2012) L. N. Murillo   mBio

Rethinking Biosafety in Research on Potential Pandemic Pathogens

(2012) M. Lipsitch et al.   mBio

The Pause on Avian H5N1 Influenza Virus Transmission Research Should Be Ended

(2012) R. A. M. Fouchier et al.   mBio

Neuraminidase Inhibitor Sensitivity and Receptor-Binding Specificity of Cambodian Clade 1 Highly Pathogenic H5N1 Influenza Virus

(2011) M. Naughtin et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Effect of receptor binding domain mutations on receptor binding and transmissibility of avian influenza H5N1 viruses

(2011) Taronna R. Maines et al.   VIROLOGY

In vitro evolution of H5N1 avian influenza virus toward human-type receptor specificity

(2011) Li-Mei Chen et al.   VIROLOGY

Differential Contribution of PB1-F2 to the Virulence of Highly Pathogenic H5N1 Influenza A Virus in Mammalian and Avian Species

(2011) Mirco Schmolke et al.   PLoS Pathogens

Pathogenicity of highly pathogenic avian H5N1 influenza A viruses isolated from humans between 2003 and 2008 in northern Vietnam

(2010) Q. M. Le et al.   JOURNAL OF GENERAL VIROLOGY

Glycosylation at 158N of the Hemagglutinin Protein and Receptor Binding Specificity Synergistically Affect the Antigenicity and Immunogenicity of a Live Attenuated H5N1 A/Vietnam/1203/2004 Vaccine Virus in Ferrets

(2010) W. Wang et al.   JOURNAL OF VIROLOGY

In Vitro Assessment of Attachment Pattern and Replication Efficiency of H5N1 Influenza A Viruses with Altered Receptor Specificity

(2010) S. Chutinimitkul et al.   JOURNAL OF VIROLOGY

Viremia Associated with Fatal Outcomes in Ferrets Infected with Avian H5N1 Influenza Virus

(2010) Xue Wang et al.   PLoS One

Structures of Receptor Complexes of a North American H7N2 Influenza Hemagglutinin with a Loop Deletion in the Receptor Binding Site

(2010) Hua Yang et al.   PLoS Pathogens

Selection of H5N1 Influenza Virus PB2 during Replication in Humans

(2009) Q. M. Le et al.   JOURNAL OF VIROLOGY

Identification of Amino Acids in HA and PB2 Critical for the Transmission of H5N1 Avian Influenza Viruses in a Mammalian Host

(2009) Yuwei Gao et al.   PLoS Pathogens

Evolution of drug resistance in multiple distinct lineages of H5N1 avian influenza

(2008) Andrew W. Hill et al.   INFECTION GENETICS AND EVOLUTION

Recent Avian H5N1 Viruses Exhibit Increased Propensity for Acquiring Human Receptor Specificity

(2008) James Stevens et al.   JOURNAL OF MOLECULAR BIOLOGY

A new influenza virus virulence determinant: The NS1 protein four C-terminal residues modulate pathogenicity

(2008) D. Jackson et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Human-Like Receptor Specificity Does Not Affect the Neuraminidase-Inhibitor Susceptibility of H5N1 Influenza Viruses

(2008) Natalia A. Ilyushina et al.   PLoS Pathogens