The Effect of the PB2 Mutation 627K on Highly Pathogenic H5N1 Avian Influenza Virus Is Dependent on the Virus Lineage

History of highly pathogenic avian influenza

(2016) D.J. ALEXANDER et al.   REVUE SCIENTIFIQUE ET TECHNIQUE-OFFICE INTERNATIONAL DES EPIZOOTIES

The Influenza A Virus PB2, PA, NP, and M Segments Play a Pivotal Role during Genome Packaging

(2012) Q. Gao et al.   JOURNAL OF VIROLOGY

Investigation of Influenza Virus Polymerase Activity in Pig Cells

(2012) O. Moncorge et al.   JOURNAL OF VIROLOGY

Experimental adaptation of an influenza H5 HA confers respiratory droplet transmission to a reassortant H5 HA/H1N1 virus in ferrets

(2012) Masaki Imai et al.   NATURE

An in vitro network of intermolecular interactions between viral RNA segments of an avian H5N2 influenza A virus: comparison with a human H3N2 virus

(2012) Cyrille Gavazzi et al.   NUCLEIC ACIDS RESEARCH

Role of Position 627 of PB2 and the Multibasic Cleavage Site of the Hemagglutinin in the Virulence of H5N1 Avian Influenza Virus in Chickens and Ducks

(2012) Karel A. Schat et al.   PLoS One

Molecular Basis of Efficient Replication and Pathogenicity of H9N2 Avian Influenza Viruses in Mice

(2012) Xiaokang Li et al.   PLoS One

A Single E627K Mutation in the PB2 Protein of H9N2 Avian Influenza Virus Increases Virulence by Inducing Higher Glucocorticoids (GCs) Level

(2012) Jin Tian et al.   PLoS One

Airborne Transmission of Influenza A/H5N1 Virus Between Ferrets

(2012) S. Herfst et al.   SCIENCE

The Potential for Respiratory Droplet-Transmissible A/H5N1 Influenza Virus to Evolve in a Mammalian Host

(2012) C. A. Russell et al.   SCIENCE

Interaction network linking the human H3N2 influenza A virus genomic RNA segments

(2012) Emilie Fournier et al.   VACCINE

Adaptive mutations in NEP compensate for defective H5N1 RNA replication in cultured human cells

(2012) Benjamin Mänz et al.   Nature Communications

Combination of PB2 271A and SR Polymorphism at Positions 590/591 Is Critical for Viral Replication and Virulence of Swine Influenza Virus in Cultured Cells and In Vivo

(2011) Q. Liu et al.   JOURNAL OF VIROLOGY

Reversion of PB2-627E to -627K during Replication of an H5N1 Clade 2.2 Virus in Mammalian Hosts Depends on the Origin of the Nucleoprotein

(2011) J. Bogs et al.   JOURNAL OF VIROLOGY

Virulence and Genetic Compatibility of Polymerase Reassortant Viruses Derived from the Pandemic (H1N1) 2009 Influenza Virus and Circulating Influenza A Viruses

(2011) M.-S. Song et al.   JOURNAL OF VIROLOGY

A supramolecular assembly formed by influenza A virus genomic RNA segments

(2011) Emilie Fournier et al.   NUCLEIC ACIDS RESEARCH

Pathogenicity of two Egyptian H5N1 highly pathogenic avian influenza viruses in domestic ducks

(2010) J. L. Wasilenko et al.   ARCHIVES OF VIROLOGY

Evolution of highly pathogenic avian H5N1 influenza viruses and the emergence of dominant variants

(2010) G. Neumann et al.   JOURNAL OF GENERAL VIROLOGY

PB2 Residue 271 Plays a Key Role in Enhanced Polymerase Activity of Influenza A Viruses in Mammalian Host Cells

(2010) K. A. Bussey et al.   JOURNAL OF VIROLOGY

Evidence for Avian and Human Host Cell Factors That Affect the Activity of Influenza Virus Polymerase

(2010) O. Moncorge et al.   JOURNAL OF VIROLOGY

Correlation between polymerase activity and pathogenicity in two duck H5N1 influenza viruses suggests that the polymerase contributes to pathogenicity

(2010) Bo Wah Leung et al.   VIROLOGY

Pathogenicity of swine influenza viruses possessing an avian or swine-origin PB2 polymerase gene evaluated in mouse and pig models

(2010) Wenjun Ma et al.   VIROLOGY

Characterization of influenza virus sialic acid receptors in minor poultry species

(2010) Brian Kimble et al.   Virology Journal

The effect of age on the pathogenesis of a highly pathogenic avian influenza (HPAI) H5N1 virus in Pekin ducks (Anas platyrhynchos) infected experimentally

(2009) Brandon Z. Löndt et al.   Influenza and Other Respiratory Viruses

Genome packaging in influenza A virus

(2009) E. C. Hutchinson et al.   JOURNAL OF GENERAL VIROLOGY

Ostrich Involvement in the Selection of H5N1 Influenza Virus Possessing Mammalian-Type Amino Acids in the PB2 Protein

(2009) K. Shinya et al.   JOURNAL OF VIROLOGY

Characterization of the H5N1 Highly Pathogenic Avian Influenza Virus Derived from Wild Pikas in China

(2009) J. Zhou et al.   JOURNAL OF VIROLOGY

Adaptive strategies of the influenza virus polymerase for replication in humans

(2009) Andrew Mehle et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Transmission of Influenza Virus in a Mammalian Host Is Increased by PB2 Amino Acids 627K or 627E/701N

(2009) John Steel et al.   PLoS Pathogens

Host Restriction of Avian Influenza Viruses at the Level of the Ribonucleoproteins

(2008) Nadia Naffakh et al.   Annual Review of Microbiology

Pathogenesis of highly pathogenic avian influenza A/turkey/Turkey/1/2005 H5N1 in Pekin ducks (Anas platyrhynchos) infected experimentally

(2008) Brandon Z. Löndt et al.   AVIAN PATHOLOGY

Recent Avian H5N1 Viruses Exhibit Increased Propensity for Acquiring Human Receptor Specificity

(2008) James Stevens et al.   JOURNAL OF MOLECULAR BIOLOGY