Autophagy induction by SIRT6 is involved in oxidative stress-induced neuronal damage

The autophagy pathway maintained signaling crosstalk with the Keap1–Nrf2 system through p62 in auditory cells under oxidative stress

(2015) Ken Hayashi et al.   CELLULAR SIGNALLING

Icariin Promotes Angiogenic Differentiation and Prevents Oxidative Stress-Induced Autophagy in Endothelial Progenitor Cells

(2015) Yubo Tang et al.   STEM CELLS

Oxidative stress and autophagy: the clash between damage and metabolic needs

(2014) G Filomeni et al.   CELL DEATH AND DIFFERENTIATION

Biochemical Characterization of Sirtuin 6 in the Brain and Its Involvement in Oxidative Stress Response

(2014) Alessio Cardinale et al.   NEUROCHEMICAL RESEARCH

The Role of miR-34a in the Hepatoprotective Effect of Hydrogen Sulfide on Ischemia/Reperfusion Injury in Young and Old Rats

(2014) Xinli Huang et al.   PLoS One

MDM2-mediated degradation of SIRT6 phosphorylated by AKT1 promotes tumorigenesis and trastuzumab resistance in breast cancer

(2014) U. Thirumurthi et al.   Science Signaling

SIRT1 Positively Regulates Autophagy and Mitochondria Function in Embryonic Stem Cells Under Oxidative Stress

(2014) Xuan Ou et al.   STEM CELLS

Chromatin and beyond: the multitasking roles for SIRT6

(2014) Sita Kugel et al.   TRENDS IN BIOCHEMICAL SCIENCES

Upregulated autophagy protects cardiomyocytes from oxidative stress-induced toxicity

(2013) Debapriya Dutta et al.   Autophagy

Decreased expression of sirtuin 6 is associated with release of high mobility group box-1 after cerebral ischemia

(2013) Ok-Hee Lee et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

A miR-34a-SIRT6 axis in the squamous cell differentiation network

(2013) Karine Lefort et al.   EMBO JOURNAL

The Role of SIRT6 Protein in Aging and Reprogramming of Human Induced Pluripotent Stem Cells

(2013) Amit Sharma et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Activation of the Protein Deacetylase SIRT6 by Long-chain Fatty Acids and Widespread Deacylation by Mammalian Sirtuins

(2013) Jessica L. Feldman et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Autophagy Induction by SIRT6 through Attenuation of Insulin-like Growth Factor Signaling Is Involved in the Regulation of Human Bronchial Epithelial Cell Senescence

(2013) N. Takasaka et al.   JOURNAL OF IMMUNOLOGY

The Ubiquitin Ligase CHIP Prevents SirT6 Degradation through Noncanonical Ubiquitination

(2013) Sarah M. Ronnebaum et al.   MOLECULAR AND CELLULAR BIOLOGY

Adiponectin Modulates Oxidative Stress-Induced Autophagy in Cardiomyocytes

(2013) Eric E. Essick et al.   PLoS One

CHIP has a protective role against oxidative stress-induced cell death through specific regulation of Endonuclease G

(2013) J S Lee et al.   Cell Death & Disease

USP10 Antagonizes c-Myc Transcriptional Activation through SIRT6 Stabilization to Suppress Tumor Formation

(2013) Zhenghong Lin et al.   Cell Reports

Inhibition of SIRT6 in prostate cancer reduces cell viability and increases sensitivity to chemotherapeutics

(2013) Yewei Liu et al.   Protein & Cell

Curcumin induces autophagy to protect vascular endothelial cell survival from oxidative stress damage

(2012) Jing Han et al.   Autophagy

Suppression of Acquired Docetaxel Resistance in Prostate Cancer through Depletion of Notch- and Hedgehog-Dependent Tumor-Initiating Cells

(2012) Josep Domingo-Domenech et al.   CANCER CELL

The sirtuin SIRT6 regulates lifespan in male mice

(2012) Yariv Kanfi et al.   NATURE

The sirtuin SIRT6 blocks IGF-Akt signaling and development of cardiac hypertrophy by targeting c-Jun

(2012) Nagalingam R Sundaresan et al.   NATURE MEDICINE

Molecular definitions of cell death subroutines: recommendations of the Nomenclature Committee on Cell Death 2012

(2011) L Galluzzi et al.   CELL DEATH AND DIFFERENTIATION

miR-33a/b contribute to the regulation of fatty acid metabolism and insulin signaling

(2011) A. Davalos et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mammalian Sirtuins: Biological Insights and Disease Relevance

(2010) Marcia C. Haigis et al.   Annual Review of Pathology-Mechanisms of Disease

Autophagy and the Integrated Stress Response

(2010) Guido Kroemer et al.   MOLECULAR CELL

Regulation Mechanisms and Signaling Pathways of Autophagy

(2009) Congcong He et al.   Annual Review of Genetics

SIRT6 is a histone H3 lysine 9 deacetylase that modulates telomeric chromatin

(2008) Eriko Michishita et al.   NATURE