The sirtuin SIRT6 regulates lifespan in male mice

Regulation of Caenorhabditis elegans lifespan by sir-2.1 transgenes

(2011) Mohan Viswanathan et al.   NATURE

Absence of effects of Sir2 overexpression on lifespan in C. elegans and Drosophila

(2011) Camilla Burnett et al.   NATURE

The Evolutionarily Conserved Longevity Determinants HCF-1 and SIR-2.1/SIRT1 Collaborate to Regulate DAF-16/FOXO

(2011) Gizem Rizki et al.   PLoS Genetics

The genetics of ageing

(2010) Cynthia J. Kenyon   NATURE

Dietary Restriction: Standing Up for Sirtuins

(2010) J. A. Baur et al.   SCIENCE

Sirt1 improves healthy ageing and protects from metabolic syndrome-associated cancer

(2010) Daniel Herranz et al.   Nature Communications

Aging in inbred strains of mice: study design and interim report on median lifespans and circulating IGF1 levels

(2009) Rong Yuan et al.   AGING CELL

SIRT6 protects against pathological damage caused by diet-induced obesity

(2009) Yariv Kanfi et al.   AGING CELL

Genes and gene expression modules associated with caloric restriction and aging in the laboratory mouse

(2009) William R Swindell   BMC GENOMICS

SIRT6 Links Histone H3 Lysine 9 Deacetylation to NF-κB-Dependent Gene Expression and Organismal Life Span

(2009) Tiara L.A. Kawahara et al.   CELL

IGF1 and its binding proteins 3 and 1 are differentially associated with metabolic syndrome in older men

(2009) Bu B Yeap et al.   EUROPEAN JOURNAL OF ENDOCRINOLOGY

Short-Term Calorie Restriction in Male Mice Feminizes Gene Expression and Alters Key Regulators of Conserved Aging Regulatory Pathways

(2009) Preston Wayne Estep et al.   PLoS One

Ribosomal Protein S6 Kinase 1 Signaling Regulates Mammalian Life Span

(2009) C. Selman et al.   SCIENCE

Regulation of SIRT1 protein levels by nutrient availability

(2008) Yariv Kanfi et al.   FEBS LETTERS