The Role of SIRT6 Protein in Aging and Reprogramming of Human Induced Pluripotent Stem Cells

SIRT6 stabilizes DNA-dependent Protein Kinase at chromatin for DNA double-strand break repair

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MicroRNAs in Stress Signaling and Human Disease

(2012) Joshua T. Mendell et al.   CELL

The Histone Deacetylase SIRT6 Is a Tumor Suppressor that Controls Cancer Metabolism

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The sirtuin SIRT6 regulates lifespan in male mice

(2012) Yariv Kanfi et al.   NATURE

Sirtuin 1 Facilitates Generation of Induced Pluripotent Stem Cells from Mouse Embryonic Fibroblasts through the miR-34a and p53 Pathways

(2012) Yin Lau Lee et al.   PLoS One

MicroRNA Regulation of SIRT1

(2012) Munekazu Yamakuchi   Frontiers in Physiology

MicroRNA Modulation of Cholesterol Homeostasis

(2011) Carlos Fernández-Hernando et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Cell cycle-dependent deacetylation of telomeric histone H3 lysine K56 by human SIRT6

(2011) Eriko Michishita et al.   CELL CYCLE

The Efficiency of Cell Fusion-Based Reprogramming Is Affected by the Somatic Cell Type and the In Vitro Age of Somatic Cells

(2011) Pollyanna Agnes Tat et al.   Cellular Reprogramming

SIRT6 Promotes DNA Repair Under Stress by Activating PARP1

(2011) Z. Mao et al.   SCIENCE

Aging alters tissue resident mesenchymal stem cell properties

(2011) Eckhard U. Alt et al.   Stem Cell Research

MicroRegulators come of age in senescence

(2011) Myriam Gorospe et al.   TRENDS IN GENETICS

SIRT6 is required for maintenance of telomere position effect in human cells

(2011) Ruth I. Tennen et al.   Nature Communications

Dynamic Chromatin Localization of Sirt6 Shapes Stress- and Aging-Related Transcriptional Networks

(2011) Tiara L. A. Kawahara et al.   PLoS Genetics

microRNA and aging: A novel modulator in regulating the aging network

(2010) Li-Hsin Chen et al.   AGEING RESEARCH REVIEWS

Aging and disease: connections to sirtuins

(2010) Gizem Donmez et al.   AGING CELL

miR-17, miR-19b, miR-20a, and miR-106a are down-regulated in human aging

(2010) Matthias Hackl et al.   AGING CELL

Age-related changes in mesenchymal stem cells derived from rhesus macaque bone marrow

(2010) Ji Min Yu et al.   AGING CELL

Effects of Ionizing Radiation on Self-Renewal and Pluripotency of Human Embryonic Stem Cells

(2010) K. D. Wilson et al.   CANCER RESEARCH

Recent Stem Cell Advances: Induced Pluripotent Stem Cells for Disease Modeling and Stem Cell–Based Regeneration

(2010) Yoshinori Yoshida et al.   CIRCULATION

MicroRNAs Both Promote and Antagonize Longevity in C. elegans

(2010) Alexandre de Lencastre et al.   CURRENT BIOLOGY

SIRT6 Links Histone H3 Lysine 9 Deacetylation to NF-κB-Dependent Gene Expression and Organismal Life Span

(2009) Tiara L.A. Kawahara et al.   CELL

Senescence impairs successful reprogramming to pluripotent stem cells

(2009) A. Banito et al.   GENES & DEVELOPMENT

Recent progress in the biology and physiology of sirtuins

(2009) Toren Finkel et al.   NATURE

miRGen 2.0: a database of microRNA genomic information and regulation

(2009) Panagiotis Alexiou et al.   NUCLEIC ACIDS RESEARCH

c-Myc Is Dispensable for Direct Reprogramming of Mouse Fibroblasts

(2008) Marius Wernig et al.   Cell Stem Cell

Sirt7 Increases Stress Resistance of Cardiomyocytes and Prevents Apoptosis and Inflammatory Cardiomyopathy in Mice

(2008) Olesya Vakhrusheva et al.   CIRCULATION RESEARCH

SIRT6 is a histone H3 lysine 9 deacetylase that modulates telomeric chromatin

(2008) Eriko Michishita et al.   NATURE