The sirtuin SIRT6 blocks IGF-Akt signaling and development of cardiac hypertrophy by targeting c-Jun
Published 2012 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
The sirtuin SIRT6 blocks IGF-Akt signaling and development of cardiac hypertrophy by targeting c-Jun
Authors
Keywords
-
Journal
NATURE MEDICINE
Volume 18, Issue 11, Pages 1643-1650
Publisher
Springer Nature
Online
2012-10-22
DOI
10.1038/nm.2961
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- The sirtuin SIRT6 regulates lifespan in male mice
- (2012) Yariv Kanfi et al. NATURE
- Caloric restriction: powerful protection for the aging heart and vasculature
- (2011) Edward P. Weiss et al. AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY
- Identification of Genes that Elicit Disuse Muscle Atrophy via the Transcription Factors p50 and Bcl-3
- (2011) Chia-Ling Wu et al. PLoS One
- The Deacetylase SIRT1 Promotes Membrane Localization and Activation of Akt and PDK1 During Tumorigenesis and Cardiac Hypertrophy
- (2011) N. R. Sundaresan et al. Science Signaling
- Aging and disease: connections to sirtuins
- (2010) Gizem Donmez et al. AGING CELL
- The Histone Deacetylase Sirt6 Regulates Glucose Homeostasis via Hif1α
- (2010) Lei Zhong et al. CELL
- Hepatic-Specific Disruption of SIRT6 in Mice Results in Fatty Liver Formation Due to Enhanced Glycolysis and Triglyceride Synthesis
- (2010) Hyun-Seok Kim et al. Cell Metabolism
- Defining and Setting National Goals for Cardiovascular Health Promotion and Disease Reduction
- (2010) Donald M. Lloyd-Jones et al. CIRCULATION
- The role of IGF-1 resistance in obesity and type 2 diabetes-mellitus-related insulin resistance and vascular disease
- (2010) Victoria K Gatenby et al. EXPERT OPINION ON THERAPEUTIC TARGETS
- SIRT6 Deficiency Results in Severe Hypoglycemia by Enhancing Both Basal and Insulin-stimulated Glucose Uptake in Mice
- (2010) Cuiying Xiao et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- SIRT3 regulates mitochondrial fatty-acid oxidation by reversible enzyme deacetylation
- (2010) Matthew D. Hirschey et al. NATURE
- Extending Healthy Life Span--From Yeast to Humans
- (2010) L. Fontana et al. SCIENCE
- The proliferating role of insulin and insulin-like growth factors in cancer
- (2010) Emily Jane Gallagher et al. TRENDS IN ENDOCRINOLOGY AND METABOLISM
- SIRT6 protects against pathological damage caused by diet-induced obesity
- (2009) Yariv Kanfi et al. AGING CELL
- SIRT6 Links Histone H3 Lysine 9 Deacetylation to NF-κB-Dependent Gene Expression and Organismal Life Span
- (2009) Tiara L.A. Kawahara et al. CELL
- The Role of IGF-1 Receptor and Insulin Receptor Signaling for the Pathogenesis of Alzheimers Disease: From Model Organisms to Human Disease
- (2009) S. Freude et al. Current Alzheimer Research
- Effect of short term calorie restriction on pro-inflammatory NF-kB and AP-1 in aged rat kidney
- (2009) K. J. Jung et al. INFLAMMATION RESEARCH
- Peptidoglycan Enhances IL-6 Production in Human Synovial Fibroblasts via TLR2 Receptor, Focal Adhesion Kinase, Akt, and AP-1- Dependent Pathway
- (2009) Y.-C. Chiu et al. JOURNAL OF IMMUNOLOGY
- Activation of SIRT1, a class III histone deacetylase, contributes to fructose feeding-mediated induction of the α-myosin heavy chain expression
- (2008) Jyothish B. Pillai et al. AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY
- IGF2: Epigenetic regulation and role in development and disease
- (2008) Wendy Chao et al. CYTOKINE & GROWTH FACTOR REVIEWS
- Activation of Insulin-Like Growth Factor II Receptor Induces Mitochondrial-Dependent Apoptosis through Gαq and Downstream Calcineurin Signaling in Myocardial Cells
- (2008) Chun-Hsien Chu et al. ENDOCRINOLOGY
- Regulation of SIRT6 protein levels by nutrient availability
- (2008) Yariv Kanfi et al. FEBS LETTERS
- SIRT3 Is a Stress-Responsive Deacetylase in Cardiomyocytes That Protects Cells from Stress-Mediated Cell Death by Deacetylation of Ku70
- (2008) N. R. Sundaresan et al. MOLECULAR AND CELLULAR BIOLOGY
- SIRT6 is a histone H3 lysine 9 deacetylase that modulates telomeric chromatin
- (2008) Eriko Michishita et al. NATURE
Find the ideal target journal for your manuscript
Explore over 38,000 international journals covering a vast array of academic fields.
SearchAdd your recorded webinar
Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.
Upload Now