Pharmacokinetics and Pharmacodynamics of Edoxaban, a Non-Vitamin K Antagonist Oral Anticoagulant that Inhibits Clotting Factor Xa

The Effect of Rifampin on the Pharmacokinetics of Edoxaban in Healthy Adults

(2015) Jeanne Mendell et al.   CLINICAL DRUG INVESTIGATION

An open-label, phase 1 study to evaluate the effects of hepatic impairment on edoxaban pharmacokinetics and pharmacodynamics

(2015) Jeanne Mendell et al.   JOURNAL OF CLINICAL PHARMACOLOGY

Evaluation of regional gastrointestinal absorption of edoxaban using the enterion capsule

(2015) Dolly A. Parasrampuria et al.   JOURNAL OF CLINICAL PHARMACOLOGY

Population pharmacokinetics of edoxaban and its main metabolite in a dedicated renal impairment study

(2015) Siv Jönsson et al.   JOURNAL OF CLINICAL PHARMACOLOGY

2014 AHA/ACC/HRS Guideline for the Management of Patients With Atrial Fibrillation: Executive Summary

(2014) Craig T. January et al.   CIRCULATION

Population Pharmacokinetics and Dose–Exposure Proportionality of Edoxaban in Healthy Volunteers

(2014) Ophelia Q. P. Yin et al.   CLINICAL DRUG INVESTIGATION

Edoxaban population pharmacokinetics and exposure–response analysis in patients with non-valvular atrial fibrillation

(2014) Ophelia Q. P. Yin et al.   EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY

Safety and Efficacy of Edoxaban, an Oral Factor Xa Inhibitor, for Thromboprophylaxis After Total Hip Arthroplasty in Japan and Taiwan

(2014) T. Fuji et al.   JOURNAL OF ARTHROPLASTY

Population pharmacokinetic-pharmacodynamic modeling analysis of intrinsic FXa and bleeding from edoxaban treatment

(2014) SaeHeum Song et al.   JOURNAL OF CLINICAL PHARMACOLOGY

Transition of Patients From Blinded Study Drug to Open-Label Anticoagulation

(2014) Christian T. Ruff et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Safety and efficacy of edoxaban in patients undergoing hip fracture surgery

(2014) Takeshi Fuji et al.   THROMBOSIS RESEARCH

Drug-Drug Interaction Studies of Cardiovascular Drugs Involving P-Glycoprotein, an Efflux Transporter, on the Pharmacokinetics of Edoxaban, an Oral Factor Xa Inhibitor

(2013) Jeanne Mendell et al.   American Journal of Cardiovascular Drugs

The Effects of the Antiplatelet Agents, Aspirin and Naproxen, on Pharmacokinetics and Pharmacodynamics of the Anticoagulant Edoxaban, a Direct Factor Xa Inhibitor

(2013) Jeanne Mendell et al.   JOURNAL OF CARDIOVASCULAR PHARMACOLOGY

Edoxaban versus Warfarin for the Treatment of Symptomatic Venous Thromboembolism

(2013)   NEW ENGLAND JOURNAL OF MEDICINE

Edoxaban versus Warfarin in Patients with Atrial Fibrillation

(2013) Robert P. Giugliano et al.   NEW ENGLAND JOURNAL OF MEDICINE

A randomized trial of the safety, pharmacokinetics and pharmacodynamics of edoxaban, an oral factor Xa inhibitor, following a switch from warfarin

(2012) Jeanne Mendell et al.   BRITISH JOURNAL OF CLINICAL PHARMACOLOGY

Antithrombotic Therapy for VTE Disease

(2012) Clive Kearon et al.   CHEST

2012 focused update of the ESC Guidelines for the management of atrial fibrillation

(2012) et al.   EUROPEAN HEART JOURNAL

Edoxaban administration following enoxaparin: A pharmacodynamic, pharmacokinetic, and tolerability assessment in human subjects

(2012) Nobuko Matsushima et al.   THROMBOSIS AND HAEMOSTASIS

Modelling and simulation of edoxaban exposure and response relationships in patients with atrial fibrillation

(2012) Jeanne Mendell et al.   THROMBOSIS AND HAEMOSTASIS

A Thorough Electrocardiogram Study of Edoxaban, a Novel Factor Xa Inhibitor

(2011) J. Mendell et al.   JOURNAL OF CLINICAL PHARMACOLOGY

Effect of edoxaban on markers of coagulation in venous and shed blood compared with fondaparinux

(2011) Meyer Samama et al.   THROMBOSIS AND HAEMOSTASIS

Novel Oral Factor Xa and Thrombin Inhibitors in the Management of Thromboembolism

(2010) Bengt I. Eriksson et al.   Annual Review of Medicine

Clinical Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of the Novel Factor Xa Inhibitor Edoxaban in Healthy Volunteers

(2010) Koichiro Ogata et al.   JOURNAL OF CLINICAL PHARMACOLOGY

Effects of Food on the Pharmacokinetics of Edoxaban, an Oral Direct Factor Xa Inhibitor, in Healthy Volunteers

(2010) Jeanne Mendell et al.   JOURNAL OF CLINICAL PHARMACOLOGY

Randomised, parallel-group, multicentre, multinational phase 2 study comparing edoxaban, an oral factor Xa inhibitor, with warfarin for stroke prevention in patients with atrial fibrillation

(2010) Stuart Connolly et al.   THROMBOSIS AND HAEMOSTASIS

Comparison of a direct Factor Xa inhibitor, edoxaban, with dalteparin and ximelagatran: A randomised controlled trial in healthy elderly adults

(2010) Meyer M. Samama et al.   THROMBOSIS RESEARCH

Pharmacology and Management of the Vitamin K Antagonists

(2008) Jack Ansell et al.   CHEST