Edoxaban population pharmacokinetics and exposure–response analysis in patients with non-valvular atrial fibrillation

Evaluation of edoxaban in patients with atrial fibrillation and severe renal impairment

(2014) Y. Koretsune et al.   EUROPEAN HEART JOURNAL

Drug-Drug Interaction Studies of Cardiovascular Drugs Involving P-Glycoprotein, an Efflux Transporter, on the Pharmacokinetics of Edoxaban, an Oral Factor Xa Inhibitor

(2013) Jeanne Mendell et al.   American Journal of Cardiovascular Drugs

Anticoagulant Therapy with the Oral Direct Factor Xa Inhibitors Rivaroxaban, Apixaban and Edoxaban and the Thrombin Inhibitor Dabigatran Etexilate in Patients with Hepatic Impairment

(2013) Jochen Graff et al.   CLINICAL PHARMACOKINETICS

Factors Associated With Major Bleeding Events

(2013) Shaun G. Goodman et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Edoxaban versus Warfarin for the Treatment of Symptomatic Venous Thromboembolism

(2013)   NEW ENGLAND JOURNAL OF MEDICINE

Edoxaban versus Warfarin in Patients with Atrial Fibrillation

(2013) Robert P. Giugliano et al.   NEW ENGLAND JOURNAL OF MEDICINE

Indirect Comparisons of New Oral Anticoagulant Drugs for Efficacy and Safety When Used for Stroke Prevention in Atrial Fibrillation

(2012) Gregory Y.H. Lip et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Modelling and simulation of edoxaban exposure and response relationships in patients with atrial fibrillation

(2012) Jeanne Mendell et al.   THROMBOSIS AND HAEMOSTASIS

Evaluation of the novel factor Xa inhibitor edoxaban compared with warfarin in patients with atrial fibrillation: Design and rationale for the Effective aNticoaGulation with factor xA next GEneration in Atrial Fibrillation–Thrombolysis In Myocardial Infarction study 48 (ENGAGE AF–TIMI 48)

(2010) Christian T. Ruff et al.   AMERICAN HEART JOURNAL

Clinical Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of the Novel Factor Xa Inhibitor Edoxaban in Healthy Volunteers

(2010) Koichiro Ogata et al.   JOURNAL OF CLINICAL PHARMACOLOGY

Membrane transporters in drug development

(2010)   NATURE REVIEWS DRUG DISCOVERY

Randomised, parallel-group, multicentre, multinational phase 2 study comparing edoxaban, an oral factor Xa inhibitor, with warfarin for stroke prevention in patients with atrial fibrillation

(2010) Stuart Connolly et al.   THROMBOSIS AND HAEMOSTASIS

Oral direct factor Xa inhibition with edoxaban for thromboprophylaxis after elective total hip replacement

(2010) Alexander Cohen et al.   THROMBOSIS AND HAEMOSTASIS

Effects of Drug Transporters on Volume of Distribution

(2009) Anita Grover et al.   AAPS Journal

A review on the impact of P-glycoprotein on the penetration of drugs into the brain. Focus on psychotropic drugs

(2007) Kristian Linnet et al.   EUROPEAN NEUROPSYCHOPHARMACOLOGY