Population pharmacokinetics of edoxaban and its main metabolite in a dedicated renal impairment study

Population Pharmacokinetics and Dose–Exposure Proportionality of Edoxaban in Healthy Volunteers

(2014) Ophelia Q. P. Yin et al.   CLINICAL DRUG INVESTIGATION

Edoxaban population pharmacokinetics and exposure–response analysis in patients with non-valvular atrial fibrillation

(2014) Ophelia Q. P. Yin et al.   EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY

Population pharmacokinetic-pharmacodynamic modeling analysis of intrinsic FXa and bleeding from edoxaban treatment

(2014) SaeHeum Song et al.   JOURNAL OF CLINICAL PHARMACOLOGY

Drug-Drug Interaction Studies of Cardiovascular Drugs Involving P-Glycoprotein, an Efflux Transporter, on the Pharmacokinetics of Edoxaban, an Oral Factor Xa Inhibitor

(2013) Jeanne Mendell et al.   American Journal of Cardiovascular Drugs

Edoxaban versus Warfarin in Patients with Atrial Fibrillation

(2013) Robert P. Giugliano et al.   NEW ENGLAND JOURNAL OF MEDICINE

Characterisation of exposure versus response of edoxaban in patients undergoing total hip replacement surgery

(2012) S. Rohatagi et al.   THROMBOSIS AND HAEMOSTASIS

Modelling and simulation of edoxaban exposure and response relationships in patients with atrial fibrillation

(2012) Jeanne Mendell et al.   THROMBOSIS AND HAEMOSTASIS

Prediction-Corrected Visual Predictive Checks for Diagnosing Nonlinear Mixed-Effects Models

(2011) Martin Bergstrand et al.   AAPS Journal

Clinical Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of the Novel Factor Xa Inhibitor Edoxaban in Healthy Volunteers

(2010) Koichiro Ogata et al.   JOURNAL OF CLINICAL PHARMACOLOGY

Effects of Food on the Pharmacokinetics of Edoxaban, an Oral Direct Factor Xa Inhibitor, in Healthy Volunteers

(2010) Jeanne Mendell et al.   JOURNAL OF CLINICAL PHARMACOLOGY

Importance of Shrinkage in Empirical Bayes Estimates for Diagnostics: Problems and Solutions

(2009) Radojka M. Savic et al.   AAPS Journal

Likelihood based approaches to handling data below the quantification limit using NONMEM VI

(2008) Jae Eun Ahn et al.   JOURNAL OF PHARMACOKINETICS AND PHARMACODYNAMICS

Mechanism-Based Concepts of Size and Maturity in Pharmacokinetics

(2007) B.J. Anderson et al.   Annual Review of Pharmacology and Toxicology