Cysteine redox state plays a key role in the inter-domain movements of HMGB1: a molecular dynamics simulation study

EGCG in Green Tea Induces Aggregation of HMGB1 Protein through Large Conformational Changes with Polarized Charge Redistribution

(2016) Xuan-Yu Meng et al.   Scientific Reports

Structural insight into the interaction between the Hox and HMGB1 and understanding of the HMGB1-enhancing effect of Hox-DNA binding

(2015) Hyun-Hwi Kim et al.   BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS

MD-2 is required for disulfide HMGB1–dependent TLR4 signaling

(2015) Huan Yang et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Theoretical study of the dimerization of aqueous beryllium cations

(2015) Xiaoyan Jin et al.   JOURNAL OF MOLECULAR MODELING

The I-TASSER Suite: protein structure and function prediction

(2015) Jianyi Yang et al.   NATURE METHODS

Two high-mobility group box domains act together to underwind and kink DNA

(2015) R. Sánchez-Giraldo et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Integrating protein structural dynamics and evolutionary analysis with Bio3D

(2014) Lars Skjærven et al.   BMC BIOINFORMATICS

Classification of Intrinsically Disordered Regions and Proteins

(2014) Robin van der Lee et al.   CHEMICAL REVIEWS

GMXPBSA 2.0: A GROMACS tool to perform MM/PBSA and computational alanine scanning

(2014) C. Paissoni et al.   COMPUTER PHYSICS COMMUNICATIONS

Structural Insights into the Mechanism of Negative Regulation of Single-box High Mobility Group Proteins by the Acidic Tail Domain

(2014) Katherine Stott et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

HMGB1 in health and disease

(2014) Rui Kang et al.   MOLECULAR ASPECTS OF MEDICINE

Energy landscapes of functional proteins are inherently risky

(2014) Anne Gershenson et al.   Nature Chemical Biology

The Role of High Mobility Group Box 1 in Innate Immunity

(2014) Shin-Ae Lee et al.   YONSEI MEDICAL JOURNAL

Redox-sensitive structural change in the A-domain of HMGB1 and its implication for the binding to cisplatin modified DNA

(2013) Jing Wang et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

GROMACS 4.5: a high-throughput and highly parallel open source molecular simulation toolkit

(2013) Sander Pronk et al.   BIOINFORMATICS

The roles of conditional disorder in redox proteins

(2013) Dana Reichmann et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

Protein dynamics and motions in relation to their functions: several case studies and the underlying mechanisms

(2013) Li-Quan Yang et al.   JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS

The many faces of HMGB1: molecular structure-functional activity in inflammation, apoptosis, and chemotaxis

(2013) Huan Yang et al.   JOURNAL OF LEUKOCYTE BIOLOGY

How Well Does a Funneled Energy Landscape Capture the Folding Mechanism of Spectrin Domains?

(2013) Robert B. Best   JOURNAL OF PHYSICAL CHEMISTRY B

Classification of Domain Movements in Proteins Using Dynamic Contact Graphs

(2013) Daniel Taylor et al.   PLoS One

MetaDisorder: a meta-server for the prediction of intrinsic disorder in proteins

(2012) Lukasz P Kozlowski et al.   BMC BIOINFORMATICS

Mutually exclusive redox forms of HMGB1 promote cell recruitment or proinflammatory cytokine release

(2012) Emilie Venereau et al.   JOURNAL OF EXPERIMENTAL MEDICINE

HMGB1: A multifunctional alarmin driving autoimmune and inflammatory disease

(2012) Helena Erlandsson Harris et al.   Nature Reviews Rheumatology

Exploring Protein Dynamics Space: The Dynasome as the Missing Link between Protein Structure and Function

(2012) Ulf Hensen et al.   PLoS One

Exploring PHD Fingers and H3K4me0 Interactions with Molecular Dynamics Simulations and Binding Free Energy Calculations: AIRE-PHD1, a Comparative Study

(2012) Dimitrios Spiliotopoulos et al.   PLoS One

Linkers in the structural biology of protein-protein interactions

(2012) Vishnu Priyanka Reddy Chichili et al.   PROTEIN SCIENCE

HMGB1-Facilitated p53 DNA Binding Occurs via HMG-Box/p53 Transactivation Domain Interaction, Regulated by the Acidic Tail

(2012) John P. Rowell et al.   STRUCTURE

High Mobility Group Box Protein-1 in Wound Repair

(2012) Elia Ranzato et al.   Cells

HMGB1 Is a Therapeutic Target for Sterile Inflammation and Infection

(2011) Ulf Andersson et al.   Annual Review of Immunology

HMGB proteins and transcriptional regulation

(2010) Tetsuya Ueda et al.   Biochimica et Biophysica Acta-Gene Regulatory Mechanisms

HMGB proteins: Interactions with DNA and chromatin

(2010) Michal Štros   Biochimica et Biophysica Acta-Gene Regulatory Mechanisms

The HADDOCK web server for data-driven biomolecular docking

(2010) Sjoerd J de Vries et al.   Nature Protocols

I-TASSER: a unified platform for automated protein structure and function prediction

(2010) Ambrish Roy et al.   Nature Protocols

A critical cysteine is required for HMGB1 binding to Toll-like receptor 4 and activation of macrophage cytokine release

(2010) H. Yang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

HMGB proteins function as universal sentinels for nucleic-acid-mediated innate immune responses

(2009) Hideyuki Yanai et al.   NATURE

The structural basis of lipopolysaccharide recognition by the TLR4–MD-2 complex

(2009) Beom Seok Park et al.   NATURE

Exploring the Free Energy Landscape: From Dynamics to Networks and Back

(2009) Diego Prada-Gracia et al.   PLoS Computational Biology