Continuous flow Negishi cross-couplings employing silica-supported Pd-PEPPSI–IPr precatalyst

Supported Catalysis in Continuous-Flow Microreactors

(2015) Rajesh Munirathinam et al.   ADVANCED SYNTHESIS & CATALYSIS

Selective Monoarylation of Primary Amines Using the Pd-PEPPSI-IPentClPrecatalyst

(2015) Sepideh Sharif et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

The Selective Cross-Coupling of Secondary Alkyl Zinc Reagents to Five-Membered-Ring Heterocycles Using Pd-PEPPSI-IHeptCl

(2015) Bruce Atwater et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Electrostatic Grafting of a Palladium N-Heterocyclic Carbene Catalyst on a Periodic Mesoporous Organosilica and its Application in the Suzuki-Miyaura Reaction

(2015) Fatemeh Rajabi et al.   ChemCatChem

An Alternative Approach to PEPPSI Catalysts: From Palladium Isonitriles to Highly Active Unsymmetrically Substituted PEPPSI Catalysts

(2015) Anna Zeiler et al.   CHEMISTRY-A EUROPEAN JOURNAL

PEPPSI-Effect on Suzuki-Miyaura Reactions Using 4,5-Dicyano-1,3-dimesitylimidazol-2-ylidene-Palladium Complexes: A Comparison betweentrans-Ligands

(2015) Heiko Baier et al.   EUROPEAN JOURNAL OF INORGANIC CHEMISTRY

Efficient and Versatile Buchwald-Hartwig Amination of (Hetero)aryl Chlorides Using the Pd-PEPPSI-IPr(NMe2)2Precatalyst in the Presence of Carbonate Base

(2015) Yin Zhang et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

SiliaCat: A Versatile Catalyst Series for Synthetic Organic Chemistry

(2015) Rosaria Ciriminna et al.   ORGANIC PROCESS RESEARCH & DEVELOPMENT

Benchmarking Immobilized Di- and Triarylphosphine Palladium Catalysts for Continuous-Flow Cross-Coupling Reactions: Efficiency, Durability, and Metal Leaching Studies

(2015) Roberto Greco et al.   ACS Catalysis

Heterogenization of Pd–NHC complexes onto a silica support and their application in Suzuki–Miyaura coupling under batch and continuous flow conditions

(2015) Alberto Martínez et al.   Catalysis Science & Technology

First Example of Alkyl–Aryl Negishi Cross-Coupling in Flow: Mild, Efficient and Clean Introduction of Functionalized Alkyl Groups

(2015) Brecht Egle et al.   Journal of Flow Chemistry

On The Remarkably Different Role of Salt in the Cross-Coupling of Arylzincs From That Seen With Alkylzincs

(2014) Lucas C. McCann et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Room-Temperature Amination of Deactivated Aniline and Aryl Halide Partners with Carbonate Base Using a Pd-PEPPSI-IPentCl-o-Picoline Catalyst

(2014) Matthew Pompeo et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

The use of the sterically demanding IPr* and related ligands in catalysis

(2014) Frédéric Izquierdo et al.   CHEMICAL COMMUNICATIONS

Multicomponent, Flow Diazotization/Mizoroki-Heck Coupling Protocol: Dispelling Myths about Working with Diazonium Salts

(2014) Kumara S. Nalivela et al.   CHEMISTRY-A EUROPEAN JOURNAL

[(IPent)PdCl2(morpholine)]: A Readily Activated Precatalyst for Room-Temperature, Additive-Free Carbon-Sulfur Coupling

(2014) Jennifer L. Farmer et al.   CHEMISTRY-A EUROPEAN JOURNAL

‘Auto-click’ functionalization for diversified copper(i) and gold(i) NHCs

(2014) Houssein Ibrahim et al.   DALTON TRANSACTIONS

[Pd(IPr*OMe)(cin)Cl] (cin = Cinnamyl): A Versatile Catalyst for C–N and C–C Bond Formation

(2014) Gulluzar Bastug et al.   ORGANOMETALLICS

Pd–PEPPSI-Type Expanded Ring N-Heterocyclic Carbene Complexes: Synthesis, Characterization, and Catalytic Activity in Suzuki–Miyaura Cross Coupling

(2014) Jay J. Dunsford et al.   ORGANOMETALLICS

Robust and reusable supported palladium catalysts for cross-coupling reactions in flow

(2014) William R. Reynolds et al.   Catalysis Science & Technology

Highly Active Mononuclear NAC-Gold(I) Catalysts

(2013) Maria Camila Blanco Jaimes et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Simple and rapid hydrogenation ofp-nitrophenol with aqueous formic acid in catalytic flow reactors

(2013) Rahat Javaid et al.   Beilstein Journal of Organic Chemistry

Reusable and highly active supported copper(i)–NHC catalysts for Click chemistry

(2013) John-Michael Collinson et al.   CHEMICAL COMMUNICATIONS

Sulfination by Using Pd-PEPPSI Complexes: Studies into Precatalyst Activation, Cationic and Solvent Effects and the Role of Butoxide Base

(2013) Mahmoud Sayah et al.   CHEMISTRY-A EUROPEAN JOURNAL

Potassium Isopropoxide: For Sulfination It is the Only Base You Need!

(2013) Mahmoud Sayah et al.   CHEMISTRY-A EUROPEAN JOURNAL

Continuous process technology: a tool for sustainable production

(2013) Charlotte Wiles et al.   GREEN CHEMISTRY

(IPr)Pd(pydc) (pydc = pyridine-2,6-dicarboxylate) – A highly active precatalyst for the sterically hindered C–N coupling reactions

(2013) Yan-Jing Li et al.   JOURNAL OF ORGANOMETALLIC CHEMISTRY

Continuous Synthesis and Use of N-Heterocyclic Carbene Copper(I) Complexes from Insoluble Cu2O

(2013) Suzanne M. Opalka et al.   ORGANIC LETTERS

Carbon–Heteroatom Coupling Using Pd-PEPPSI Complexes

(2013) Cory Valente et al.   ORGANIC PROCESS RESEARCH & DEVELOPMENT

Chiral PEPPSI Complexes: Synthesis, Characterization, and Application in Asymmetric Suzuki–Miyaura Coupling Reactions

(2013) Laure Benhamou et al.   ORGANOMETALLICS

A solid supported palladium(0) nano/microparticle catalyzed ultrasound induced continuous flow technique for large scale Suzuki reactions

(2013) Arun K. Shil et al.   RSC Advances

Higher-Order Zincates as Transmetalators in Alkyl-Alkyl Negishi Cross-Coupling

(2012) Lucas C. McCann et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Pd-PEPPSI-IPentCl: A Highly Effective Catalyst for the Selective Cross-Coupling of Secondary Organozinc Reagents

(2012) Matthew Pompeo et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

The Development of Bulky Palladium NHC Complexes for the Most-Challenging Cross-Coupling Reactions

(2012) Cory Valente et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Pd-PEPPSI-IPentCl: An Effective Catalyst for the Preparation of Triarylamines

(2012) Ka Hou Hoi et al.   CHEMISTRY-A EUROPEAN JOURNAL

PEPPSI-Type Palladium Complexes Containing Basic 1,2,3-Triazolylidene Ligands and Their Role in Suzuki-Miyaura Catalysis

(2012) Daniel Canseco-Gonzalez et al.   CHEMISTRY-A EUROPEAN JOURNAL

Access to functionalised silver(i) and gold(i) N-heterocyclic carbenes by [2 + 3] dipolar cycloadditions

(2012) Audrey Hospital et al.   DALTON TRANSACTIONS

Recyclable Hybrid Silica-Based Catalysts Derived from Pd-NHC Complexes for Suzuki, Heck and Sonogashira Reactions

(2012) Guadalupe Borja et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Regioselective Cross-Coupling of Allylboronic Acid Pinacol Ester Derivatives with Aryl Halides via Pd-PEPPSI-IPent

(2012) Jennifer L. Farmer et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

[Pd(IPr*)(3-Cl-pyridinyl)Cl2]: A Novel and Efficient PEPPSI Precatalyst

(2012) Anthony Chartoire et al.   ORGANOMETALLICS

A direct and practical approach for the synthesis of N-heterocyclic carbene coinage metal complexes

(2012) Shifa Zhu et al.   TETRAHEDRON

Differentiating CBr and CCl Bond Activation by Using Solvent Polarity: Applications to Orthogonal Alkyl-Alkyl Negishi Reactions

(2011) Niloufar Hadei et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Negishi cross-coupling of secondary alkylzinc halides with aryl/heteroaryl halides using Pd–PEPPSI–IPent

(2011) Selçuk Çalimsiz et al.   CHEMICAL COMMUNICATIONS

N-Heterocyclic carbene (NHC) ligands and palladium in homogeneous cross-coupling catalysis: a perfect union

(2011) George C. Fortman et al.   CHEMICAL SOCIETY REVIEWS

Amination with Pd-NHC Complexes: Rate and Computational Studies on the Effects of the Oxidative Addition Partner

(2011) Ka Hou Hoi et al.   CHEMISTRY-A EUROPEAN JOURNAL

In Situ Generation and Intramolecular Schmidt Reaction of Keto Azides in a Microwave-Assisted Flow Format

(2011) Thomas O. Painter et al.   CHEMISTRY-A EUROPEAN JOURNAL

Amination with PdNHC Complexes: Rate and Computational Studies Involving Substituted Aniline Substrates

(2011) Ka Hou Hoi et al.   CHEMISTRY-A EUROPEAN JOURNAL

Potassium 2,2,5,7,8-Pentamethylchroman-6-oxide: A Rationally Designed Base for Pd-Catalysed Amination

(2011) Ka Hou Hoi et al.   CHEMISTRY-A EUROPEAN JOURNAL

Carbon-Sulfur Bond Formation of Challenging Substrates at Low Temperature by Using Pd-PEPPSI-IPent

(2011) Mahmoud Sayah et al.   CHEMISTRY-A EUROPEAN JOURNAL

Panning for gold in a hot flowing stream

(2011) Gjergji Shore et al.   GOLD BULLETIN

Continuous flow reactors: a perspective

(2011) Charlotte Wiles et al.   GREEN CHEMISTRY

Catalytic activity of PdCl2 complexes with pyridines in nitrobenzene carbonylation

(2011) Agnieszka Krogul et al.   JOURNAL OF MOLECULAR CATALYSIS A-CHEMICAL

Tin(IV) porphyrin functionalization of electrochemically active fluoride-doped tin-oxide (FTO) via Huisgen [3+2] click chemistry

(2011) Shiva Prasad et al.   JOURNAL OF PORPHYRINS AND PHTHALOCYANINES

Suzuki–Miyaura Cross-Coupling of Heteroaryl Halides and Arylboronic Acids in Continuous Flow

(2011) Timothy Noël et al.   ORGANIC LETTERS

Packed-Bed Reactors for Continuous-Flow CN Cross-Coupling

(2010) John R. Naber et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Pd-PEPPSI-IPent: Low-Temperature Negishi Cross-Coupling for the Preparation of Highly Functionalized, Tetra-ortho-Substituted Biaryls

(2010) Selçuk Çalimsiz et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Silica-Supported Palladium-Catalyzed Hiyama Cross-Coupling Reactions Using Continuous Flow System

(2010) Ga-Ram Yang et al.   BULLETIN OF THE KOREAN CHEMICAL SOCIETY

Copper N-heterocyclic carbene (NHC) complexes as carbene transfer reagents

(2010) Marc R. L. Furst et al.   CHEMICAL COMMUNICATIONS

On the role of additives in alkyl–alkyl Negishi cross-couplings

(2010) George T. Achonduh et al.   CHEMICAL COMMUNICATIONS

An Efficient Low-Temperature Stille-Migita Cross-Coupling Reaction for Heteroaromatic Compounds by Pd-PEPPSI-IPent

(2010) Meenakshi Dowlut et al.   CHEMISTRY-A EUROPEAN JOURNAL

Scaling Out by Microwave-Assisted, Continuous Flow Organic Synthesis (MACOS): Multi-Gram Synthesis of Bromo- and Fluoro-benzofused Sultams Benzthiaoxazepine-1,1-dioxides

(2010) Farman Ullah et al.   CHEMISTRY-A EUROPEAN JOURNAL

Structure-Activity Relationship Analysis of Pd-PEPPSI Complexes in Cross-Couplings: A Close Inspection of the Catalytic Cycle and the Precatalyst Activation Model

(2010) Joanna Nasielski et al.   CHEMISTRY-A EUROPEAN JOURNAL

Simple and versatile synthesis of copper and silver N-heterocyclic carbene complexes in water or organic solvents

(2010) Cécilia A. Citadelle et al.   DALTON TRANSACTIONS

Continuous Flow Palladium(II)-Catalyzed Oxidative Heck Reactions with Arylboronic Acids

(2010) Luke R. Odell et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Palladium-catalyzed amination reactions in flow: overcoming the challenges of clogging via acoustic irradiation

(2010) Timothy Noël et al.   Chemical Science

Pd-PEPPSI-IPent: An Active, Sterically Demanding Cross-Coupling Catalyst and Its Application in the Synthesis of Tetra-Ortho-Substituted Biaryls

(2009) Michael G. Organ et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Density Functional Theory Investigation of the Alkyl-Alkyl Negishi Cross-Coupling Reaction Catalyzed by N-Heterocyclic Carbene (NHC)-Pd Complexes

(2009) Gregory A. Chass et al.   CHEMISTRY-A EUROPEAN JOURNAL

Ring-opening metathesis polymerization-derived, polymer-bound Cu-catalysts for click-chemistry and hydrosilylation reactions under micellar conditions

(2009) Gajanan M. Pawar et al.   DALTON TRANSACTIONS

Fluoride-Free Hiyama and Copper- and Amine-Free Sonogashira Coupling in Air in a Mixed Aqueous Medium by a Series of PEPPSI-Themed Precatalysts

(2009) Chandrakanta Dash et al.   EUROPEAN JOURNAL OF INORGANIC CHEMISTRY

Escape from Flatland: Increasing Saturation as an Approach to Improving Clinical Success

(2009) Frank Lovering et al.   JOURNAL OF MEDICINAL CHEMISTRY

Negishi Coupling of Secondary Alkylzinc Halides with Aryl Bromides and Chlorides

(2009) Chong Han et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Well-Defined Silica-Supported Olefin Metathesis Catalysts

(2009) Daryl P. Allen et al.   ORGANIC LETTERS

Surveying Sterically Demanding N-Heterocyclic Carbene Ligands with Restricted Flexibility for Palladium-catalyzed Cross-Coupling Reactions

(2008) Sebastian Würtz et al.   ACCOUNTS OF CHEMICAL RESEARCH

Pd-Catalyzed Aryl Amination Mediated by Well Defined, N-Heterocyclic Carbene (NHC)–Pd Precatalysts, PEPPSI

(2008) Michael G. Organ et al.   CHEMISTRY-A EUROPEAN JOURNAL

One-Pot Negishi Cross-Coupling Reactions of In Situ Generated Zinc Reagents with Aryl Chlorides, Bromides, and Triflates

(2008) Shohei Sase et al.   JOURNAL OF ORGANIC CHEMISTRY

Effective Pd-Nanoparticle (PdNP)-Catalyzed Negishi Coupling Involving Alkylzinc Reagents at Room Temperature

(2008) Jing Liu et al.   ORGANIC LETTERS

Immobilization of NHC-Bearing Palladium Catalysts on Polyvinylpyridine; Applications in Suzuki-Miyaura and Hartwig-Buchwald Reactions under Batch and Continuous-Flow Conditions

(2008) Andreas Kirschning et al.   SYNTHESIS-STUTTGART

Pd-NHC (PEPPSI) Complexes: Synthetic Utility and Computational Studies into Their Reactivity

(2008) Michael Organ et al.   SYNTHESIS-STUTTGART

Pd–N-heterocyclic carbene (NHC) organic silica: synthesis and application in carbon–carbon coupling reactions

(2008) Vivek Polshettiwar et al.   TETRAHEDRON

Diels–Alder cycloadditions by microwave-assisted, continuous flow organic synthesis (MACOS): the role of metal films in the flow tube

(2007) Gjergji Shore et al.   CHEMICAL COMMUNICATIONS

High yielding alkylations of unactivated sp3and sp2centres with alkyl-9-BBN reagents using an NHC-based catalyst: Pd-PEPPSI-IPr

(2007) Cory Valente et al.   CHEMICAL COMMUNICATIONS

Pd PEPPSI-IPr-Mediated Reactions in Metal-Coated Capillaries Under MACOS: The Synthesis of Indoles by Sequential Aryl Amination/ Heck Coupling

(2007) Gjergji Shore et al.   CHEMISTRY-A EUROPEAN JOURNAL