klf2a couples mechanotransduction and zebrafish valve morphogenesis through fibronectin synthesis

Live imaging and modeling for shear stress quantification in the embryonic zebrafish heart

(2016) Francesco Boselli et al.   METHODS

Bending Gradients: How the Intestinal Stem Cell Gets Its Home

(2015) Amy E. Shyer et al.   CELL

Blood flow mechanics in cardiovascular development

(2015) Francesco Boselli et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Oscillatory Flow Modulates Mechanosensitive klf2a Expression through trpv4 and trpp2 during Heart Valve Development

(2015) Emilie Heckel et al.   CURRENT BIOLOGY

Flow-induced protein kinase A–CREB pathway acts via BMP signaling to promote HSC emergence

(2015) Peter Geon Kim et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Adenosine signaling promotes hematopoietic stem and progenitor cell emergence

(2015) Lili Jing et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Biomechanical forces promote blood development through prostaglandin E2and the cAMP–PKA signaling axis

(2015) Miguel F. Diaz et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Mutations in DCHS1 cause mitral valve prolapse

(2015) Ronen Durst et al.   NATURE

Genetic association analyses highlight biological pathways underlying mitral valve prolapse

(2015) Christian Dina et al.   NATURE GENETICS

Mitral valve disease—morphology and mechanisms

(2015) Robert A. Levine et al.   Nature Reviews Cardiology

Endothelial Cell Self-fusion during Vascular Pruning

(2015) Anna Lenard et al.   PLOS BIOLOGY

Intracardiac flow dynamics regulate atrioventricular valve morphogenesis

(2014) Stamatia Kalogirou et al.   CARDIOVASCULAR RESEARCH

Loss of Krox20 results in aortic valve regurgitation and impaired transcriptional activation of fibrillar collagen genes

(2014) Gaëlle Odelin et al.   CARDIOVASCULAR RESEARCH

Forms, forces, and stem cell fate

(2014) Evangelia Bellas et al.   CURRENT OPINION IN CELL BIOLOGY

Blood Flow and Bmp Signaling Control Endocardial Chamber Morphogenesis

(2014) Ann-Christin Dietrich et al.   DEVELOPMENTAL CELL

The Notochord Breaks Bilateral Symmetry by Controlling Cell Shapes in the Zebrafish Laterality Organ

(2014) Julien Compagnon et al.   DEVELOPMENTAL CELL

Emerging interactions between skin stem cells and their niches

(2014) Ya-Chieh Hsu et al.   NATURE MEDICINE

Multicolor two-photon light-sheet microscopy

(2014) Pierre Mahou et al.   NATURE METHODS

How to Make a Heart Valve: From Embryonic Development to Bioengineering of Living Valve Substitutes

(2014) D. MacGrogan et al.   Cold Spring Harbor Perspectives in Medicine

Biomechanical factors in the biology of aortic wall and aortic valve diseases

(2013) Magnus Bäck et al.   CARDIOVASCULAR RESEARCH

Forces in Tissue Morphogenesis and Patterning

(2013) Carl-Philipp Heisenberg et al.   CELL

Heartbeat-Driven Pericardiac Fluid Forces Contribute to Epicardium Morphogenesis

(2013) Marina Peralta et al.   CURRENT BIOLOGY

A network of epigenetic regulators guides developmental haematopoiesis in vivo

(2013) Hsuan-Ting Huang et al.   NATURE CELL BIOLOGY

Krüppel-Like Factor 2 Is Required for Normal Mouse Cardiac Development

(2013) Aditi R. Chiplunkar et al.   PLoS One

Mechanics of Epithelial Tissue Homeostasis and Morphogenesis

(2013) C. Guillot et al.   SCIENCE

Hyaluronan: A critical regulator of endothelial-to-mesenchymal transition during cardiac valve formation

(2013) Anne Karine Lagendijk et al.   TRENDS IN CARDIOVASCULAR MEDICINE

The role of filopodia in the recognition of nanotopographies

(2013) Jörg Albuschies et al.   Scientific Reports

Developmental basis for filamin-A-associated myxomatous mitral valve disease

(2012) Kimberly Sauls et al.   CARDIOVASCULAR RESEARCH

Endocardial and Epicardial Epithelial to Mesenchymal Transitions in Heart Development and Disease

(2012) Alexander von Gise et al.   CIRCULATION RESEARCH

Fluid flows and forces in development: functions, features and biophysical principles

(2012) J. B. Freund et al.   DEVELOPMENT

Mechanotransduction, PROX1, and FOXC2 Cooperate to Control Connexin37 and Calcineurin during Lymphatic-Valve Formation

(2012) Amélie Sabine et al.   DEVELOPMENTAL CELL

Extracellular-matrix tethering regulates stem-cell fate

(2012) Britta Trappmann et al.   NATURE MATERIALS

Differential expression analysis of multifactor RNA-Seq experiments with respect to biological variation

(2012) Davis J. McCarthy et al.   NUCLEIC ACIDS RESEARCH

The mechanobiology of mitral valve function, degeneration, and repair

(2012) Jennifer M. Richards et al.   Journal of Veterinary Cardiology

Planar Cell Polarity and the Developmental Control of Cell Behavior in Vertebrate Embryos

(2011) John B. Wallingford   Annual Review of Cell and Developmental Biology

A blood flow-dependent klf2a-NO signaling cascade is required for stabilization of hematopoietic stem cell programming in zebrafish embryos

(2011) L. Wang et al.   BLOOD

MicroRNA-23 Restricts Cardiac Valve Formation by Inhibiting Has2 and Extracellular Hyaluronic Acid Production

(2011) Anne Karine Lagendijk et al.   CIRCULATION RESEARCH

Distinct Cellular Mechanisms of Blood Vessel Fusion in the Zebrafish Embryo

(2011) Lukas Herwig et al.   CURRENT BIOLOGY

Dependence of cardiac trabeculation on neuregulin signaling and blood flow in zebrafish

(2011) Courtney Peshkovsky et al.   DEVELOPMENTAL DYNAMICS

A dual role for ErbB2 signaling in cardiac trabeculation

(2010) J. Liu et al.   DEVELOPMENT

Mechanical control of tissue and organ development

(2010) T. Mammoto et al.   DEVELOPMENT

MicroRNA-mediated integration of haemodynamics and Vegf signalling during angiogenesis

(2010) Stefania Nicoli et al.   NATURE

A scaling normalization method for differential expression analysis of RNA-seq data

(2010) Mark D Robinson et al.   GENOME BIOLOGY

TopHat: discovering splice junctions with RNA-Seq

(2009) Cole Trapnell et al.   BIOINFORMATICS

edgeR: a Bioconductor package for differential expression analysis of digital gene expression data

(2009) M. D. Robinson et al.   BIOINFORMATICS

TRPV4 Channels Mediate Cyclic Strain–Induced Endothelial Cell Reorientation Through Integrin-to-Integrin Signaling

(2009) Charles K. Thodeti et al.   CIRCULATION RESEARCH

Selective plane illumination microscopy techniques in developmental biology

(2009) J. Huisken et al.   DEVELOPMENT

Integrin-α9 Is Required for Fibronectin Matrix Assembly during Lymphatic Valve Morphogenesis

(2009) Eleni Bazigou et al.   DEVELOPMENTAL CELL

Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources

(2009) Da Wei Huang et al.   Nature Protocols

Reversing Blood Flows Act through klf2a to Ensure Normal Valvulogenesis in the Developing Heart

(2009) Julien Vermot et al.   PLOS BIOLOGY

High-speed imaging of developing heart valves reveals interplay of morphogenesis and function

(2008) P. J. Scherz et al.   DEVELOPMENT

Complex cell rearrangements during intersegmental vessel sprouting and vessel fusion in the zebrafish embryo

(2008) Yannick Blum et al.   DEVELOPMENTAL BIOLOGY

High-resolution in situ hybridization to whole-mount zebrafish embryos

(2007) Christine Thisse et al.   Nature Protocols