Blood flow mechanics in cardiovascular development

The Wall-stress Footprint of Blood Cells Flowing in Microvessels

(2014) Jonathan B. Freund et al.   BIOPHYSICAL JOURNAL

Reciprocal myocardial-endocardial interactions pattern the delay in atrioventricular junction conduction

(2014) M. Bressan et al.   DEVELOPMENT

High-resolution imaging of cardiomyocyte behavior reveals two distinct steps in ventricular trabeculation

(2014) D. W. Staudt et al.   DEVELOPMENT

Blood Flow and Bmp Signaling Control Endocardial Chamber Morphogenesis

(2014) Ann-Christin Dietrich et al.   DEVELOPMENTAL CELL

The role of Hath6, a newly identified shear-stress-responsive transcription factor, in endothelial cell differentiation and function

(2014) F. Fang et al.   JOURNAL OF CELL SCIENCE

Piezo1 integration of vascular architecture with physiological force

(2014) Jing Li et al.   NATURE

High-resolution reconstruction of the beating zebrafish heart

(2014) Michaela Mickoleit et al.   NATURE METHODS

Multicolor two-photon light-sheet microscopy

(2014) Pierre Mahou et al.   NATURE METHODS

Hemodynamic Forces Regulate Developmental Patterning of Atrial Conduction

(2014) Michael C. Bressan et al.   PLoS One

Piezo1, a mechanically activated ion channel, is required for vascular development in mice

(2014) S. S. Ranade et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Forces in Tissue Morphogenesis and Patterning

(2013) Carl-Philipp Heisenberg et al.   CELL

Heartbeat-Driven Pericardiac Fluid Forces Contribute to Epicardium Morphogenesis

(2013) Marina Peralta et al.   CURRENT BIOLOGY

Pulse propagation by a capacitive mechanism drives embryonic blood flow

(2013) H. Anton et al.   DEVELOPMENT

Biomechanical force in blood development: Extrinsic physical cues drive pro-hematopoietic signaling

(2013) Hyun Jung Lee et al.   DIFFERENTIATION

Krüppel-Like Factor 2 Is Required for Normal Mouse Cardiac Development

(2013) Aditi R. Chiplunkar et al.   PLoS One

Blood Flow Changes Coincide with Cellular Rearrangements during Blood Vessel Pruning in Zebrafish Embryos

(2013) Eva Kochhan et al.   PLoS One

Haemodynamically dependent valvulogenesis of zebrafish heart is mediated by flow-dependent expression of miR-21

(2013) Toshihiro Banjo et al.   Nature Communications

A Nodal-independent and tissue-intrinsic mechanism controls heart-looping chirality

(2013) Emily S. Noël et al.   Nature Communications

The Transitional Cardiac Pumping Mechanics in the Embryonic Heart

(2013) Brennan M. Johnson et al.   Cardiovascular Engineering and Technology

Stress and strain adaptation in load-dependent remodeling of the embryonic left ventricle

(2012) Christine M. Buffinton et al.   Biomechanics and Modeling in Mechanobiology

Biomechanics of early cardiac development

(2012) Sevan Goenezen et al.   Biomechanics and Modeling in Mechanobiology

Fluid flows and forces in development: functions, features and biophysical principles

(2012) J. B. Freund et al.   DEVELOPMENT

Red blood cell distribution in simplified capillary networks

(2012) D. Obrist et al.   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY A-MATHEMATICAL PHYSICAL AND ENGINEERING SCIENCES

Haemodynamics-Driven Developmental Pruning of Brain Vasculature in Zebrafish

(2012) Qi Chen et al.   PLOS BIOLOGY

The Fluid Mechanics of Cancer and Its Therapy

(2011) Petros Koumoutsakos et al.   Annual Review of Fluid Mechanics

The Pathobiology of Arrhythmogenic Cardiomyopathy

(2011) Jeffrey E. Saffitz   Annual Review of Pathology-Mechanisms of Disease

Basic and Therapeutic Aspects of Angiogenesis

(2011) Michael Potente et al.   CELL

Fluid Dynamics of Heart Development

(2011) Arvind Santhanakrishnan et al.   CELL BIOCHEMISTRY AND BIOPHYSICS

Coordinating cell behaviour during blood vessel formation

(2011) I. Geudens et al.   DEVELOPMENT

Dependence of cardiac trabeculation on neuregulin signaling and blood flow in zebrafish

(2011) Courtney Peshkovsky et al.   DEVELOPMENTAL DYNAMICS

Molecular control of endothelial cell behaviour during blood vessel morphogenesis

(2011) Shane P. Herbert et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

A dual role for ErbB2 signaling in cardiac trabeculation

(2010) J. Liu et al.   DEVELOPMENT

Pulsatile shear and Gja5 modulate arterial identity and remodeling events during flow-driven arteriogenesis

(2010) I. Buschmann et al.   DEVELOPMENT

How does the tubular embryonic heart work? Looking for the physical mechanism generating unidirectional blood flow in the valveless embryonic heart tube

(2010) Jörg Männer et al.   DEVELOPMENTAL DYNAMICS

Heartbeat regulates cardiogenesis by suppressing retinoic acid signaling via expression of miR-143

(2010) Kota Y. Miyasaka et al.   MECHANISMS OF DEVELOPMENT

MicroRNA-mediated integration of haemodynamics and Vegf signalling during angiogenesis

(2010) Stefania Nicoli et al.   NATURE

Cardiac conduction is required to preserve cardiac chamber morphology

(2010) N. C. Chi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Reversing Blood Flows Act through klf2a to Ensure Normal Valvulogenesis in the Developing Heart

(2009) Julien Vermot et al.   PLOS BIOLOGY

High-speed imaging of developing heart valves reveals interplay of morphogenesis and function

(2008) P. J. Scherz et al.   DEVELOPMENT

Computational studies of resonance wave pumping in compliant tubes

(2008) IDIT AVRAHAMI et al.   JOURNAL OF FLUID MECHANICS

Genetic and Physiologic Dissection of the Vertebrate Cardiac Conduction System

(2008) Neil C Chi et al.   PLOS BIOLOGY