Biomechanical forces promote blood development through prostaglandin E2and the cAMP–PKA signaling axis

Prostaglandin E2 Regulates Liver versus Pancreas Cell-Fate Decisions and Endodermal Outgrowth

(2014) Sahar Nissim et al.   DEVELOPMENTAL CELL

Mechanical motion promotes expression of Prg4 in articular cartilage via multiple CREB-dependent, fluid flow shear stress-induced signaling pathways

(2014) H. Ogawa et al.   GENES & DEVELOPMENT

Mouse extraembryonic arterial vessels harbor precursors capable of maturing into definitive HSCs

(2013) S. Gordon-Keylock et al.   BLOOD

Prostaglandin E2 enhances long-term repopulation but does not permanently alter inherent stem cell competitiveness

(2013) J. Hoggatt et al.   BLOOD

Prostaglandin-modulated umbilical cord blood hematopoietic stem cell transplantation

(2013) C. Cutler et al.   BLOOD

Differential stem- and progenitor-cell trafficking by prostaglandin E2

(2013) Jonathan Hoggatt et al.   NATURE

Early dynamic fate changes in haemogenic endothelium characterized at the single-cell level

(2013) Gemma Swiers et al.   Nature Communications

Recovery from hematopoietic injury by modulating prostaglandin E2 signaling post-irradiation

(2012) Jonathan Hoggatt et al.   BLOOD CELLS MOLECULES AND DISEASES

Noncanonical Wnt Signaling Maintains Hematopoietic Stem Cells in the Niche

(2012) Ryohichi Sugimura et al.   CELL

The Transcriptional Landscape of Hematopoietic Stem Cell Ontogeny

(2012) Shannon McKinney-Freeman et al.   Cell Stem Cell

Protein Kinase G and Focal Adhesion Kinase Converge on Src/Akt/β-Catenin Signaling Module in Osteoblast Mechanotransduction

(2012) Hema Rangaswami et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

PKA/CREB Signaling Triggers Initiation of Endothelial and Hematopoietic Cell Differentiation via Etv2 Induction

(2012) Kohei Yamamizu et al.   STEM CELLS

Prostaglandin E2 Increases Hematopoietic Stem Cell Survival and Accelerates Hematopoietic Recovery After Radiation Injury

(2012) Rebecca L. Porter et al.   STEM CELLS

A blood flow-dependent klf2a-NO signaling cascade is required for stabilization of hematopoietic stem cell programming in zebrafish embryos

(2011) L. Wang et al.   BLOOD

PGE2 promotes angiogenesis through EP4 and PKA C  pathway

(2011) Y. Zhang et al.   BLOOD

Canonical Wnt Signaling Regulates Hematopoiesis in a Dosage-Dependent Fashion

(2011) Tiago C. Luis et al.   Cell Stem Cell

Prostaglandin E2 Enhances Human Cord Blood Stem Cell Xenotransplants and Shows Long-Term Safety in Preclinical Nonhuman Primate Transplant Models

(2011) Wolfram Goessling et al.   Cell Stem Cell

Embryonic day 9 yolk sac and intra-embryonic hemogenic endothelium independently generate a B-1 and marginal zone progenitor lacking B-2 potential

(2011) M. Yoshimoto et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Metalloprotease-Dependent Onset of Blood Circulation in Zebrafish

(2010) Atsuo Iida et al.   CURRENT BIOLOGY

Enrichment Map: A Network-Based Method for Gene-Set Enrichment Visualization and Interpretation

(2010) Daniele Merico et al.   PLoS One

Renal and cardiovascular characterization of COX-2 knockdown mice

(2009) Francesca Seta et al.   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

Prostaglandin E2 enhances hematopoietic stem cell homing, survival, and proliferation

(2009) J. Hoggatt et al.   BLOOD

Hematopoietic Stem Cell Development Is Dependent on Blood Flow

(2009) Trista E. North et al.   CELL

Genetic Interaction of PGE2 and Wnt Signaling Regulates Developmental Specification of Stem Cells and Regeneration

(2009) Wolfram Goessling et al.   CELL

Shear Stress Induces Synthetic-to-Contractile Phenotypic Modulation in Smooth Muscle Cells via Peroxisome Proliferator-Activated Receptor α/δ Activations by Prostacyclin Released by Sheared Endothelial Cells

(2009) Min-Chien Tsai et al.   CIRCULATION RESEARCH

Continuous single-cell imaging of blood generation from haemogenic endothelium

(2009) Hanna M. Eilken et al.   NATURE

Biomechanical forces promote embryonic haematopoiesis

(2009) Luigi Adamo et al.   NATURE

Of lineage and legacy: the development of mammalian hematopoietic stem cells

(2008) Elaine Dzierzak et al.   NATURE IMMUNOLOGY

All primitive and definitive hematopoietic progenitor cells emerging before E10 in the mouse embryo are products of the yolk sac

(2007) C. T. Lux et al.   BLOOD