Histone-acetylation: a link between Alzheimer's disease and post-traumatic stress disorder?

Sodium Butyrate Improves Memory Function in an Alzheimer's Disease Mouse Model When Administered at an Advanced Stage of Disease Progression

(2018) Nambirajan Govindarajan et al.   JOURNAL OF ALZHEIMERS DISEASE

Loss of HDAC5 Impairs Memory Function: Implications for Alzheimer's Disease

(2018) Roberto Carlos Agis-Balboa et al.   JOURNAL OF ALZHEIMERS DISEASE

Dysregulation of Histone Acetylation in the APP/PS1 Mouse Model of Alzheimer's Disease

(2017) Yitshak I. Francis et al.   JOURNAL OF ALZHEIMERS DISEASE

Genome-wide analysis of H4K5 acetylation associated with fear memory in mice

(2013) C Park et al.   BMC GENOMICS

Oral Administration of Histone Deacetylase Inhibitor MS-275 Ameliorates Neuroinflammation and Cerebral Amyloidosis and Improves Behavior in a Mouse Model

(2013) Zhi-Yuan Zhang et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

A Novel Activator of CBP/p300 Acetyltransferases Promotes Neurogenesis and Extends Memory Duration in Adult Mice

(2013) S. Chatterjee et al.   JOURNAL OF NEUROSCIENCE

Loss of Histone Deacetylase 2 Improves Working Memory and Accelerates Extinction Learning

(2013) M. J. Morris et al.   JOURNAL OF NEUROSCIENCE

Histone H3 lysine methylation in cognition and intellectual disability disorders

(2013) S. Parkel et al.   LEARNING & MEMORY

Repeated valproate treatment facilitates fear extinction under specific stimulus conditions

(2013) Stephen C. Heinrichs et al.   NEUROSCIENCE LETTERS

Acetyltransferases (HATs) as Targets for Neurological Therapeutics

(2013) Anne Schneider et al.   Neurotherapeutics

Genomic targets, and histone acetylation and gene expression profiling of neural HDAC inhibition

(2013) Jose P. Lopez-Atalaya et al.   NUCLEIC ACIDS RESEARCH

Childhood Trauma and PTSD Symptoms Increase the Risk of Cognitive Impairment in a Sample of Former Indentured Child Laborers in Old Age

(2013) Andrea Burri et al.   PLoS One

Differential effects of cocaine on histone posttranslational modifications in identified populations of striatal neurons

(2013) Emmanuelle Jordi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Vorinostat ameliorates impaired fear extinction possibly via the hippocampal NMDA-CaMKII pathway in an animal model of posttraumatic stress disorder

(2013) Yasutaka Matsumoto et al.   PSYCHOPHARMACOLOGY

Interindividual Variability in Stress Susceptibility: A Role for Epigenetic Mechanisms in PTSD

(2013) Iva B. Zovkic et al.   Frontiers in Psychiatry

Exploring Epigenetic Regulation of Fear Memory and Biomarkers Associated with Post-Traumatic Stress Disorder

(2013) Stephanie A. Maddox et al.   Frontiers in Psychiatry

HDAC4 Governs a Transcriptional Program Essential for Synaptic Plasticity and Memory

(2012) Richard Sando et al.   CELL

Reducing HDAC6 ameliorates cognitive deficits in a mouse model for Alzheimer's disease

(2012) Nambirajan Govindarajan et al.   EMBO Molecular Medicine

Adaptation of the CHARM DNA methylation platform for the rat genome reveals novel brain region-specific differences

(2012) Richard S. Lee et al.   Epigenetics

Mercaptoacetamide-based class II HDAC inhibitor lowers Aβ levels and improves learning and memory in a mouse model of Alzheimer's disease

(2012) You Me Sung et al.   EXPERIMENTAL NEUROLOGY

An Essential Role for Histone Deacetylase 4 in Synaptic Plasticity and Memory Formation

(2012) M.-S. Kim et al.   JOURNAL OF NEUROSCIENCE

HDAC1 Regulates Fear Extinction in Mice

(2012) S. Bahari-Javan et al.   JOURNAL OF NEUROSCIENCE

Vorinostat, a histone deacetylase inhibitor, facilitates fear extinction and enhances expression of the hippocampal NR2B-containing NMDA receptor gene

(2012) Yosuke Fujita et al.   JOURNAL OF PSYCHIATRIC RESEARCH

Differential roles for Nr4a1 and Nr4a2 in object location vs. object recognition long-term memory

(2012) S. E. McNulty et al.   LEARNING & MEMORY

An epigenetic blockade of cognitive functions in the neurodegenerating brain

(2012) Johannes Gräff et al.   NATURE

Epigenetic mechanisms in neurological disease

(2012) Mira Jakovcevski et al.   NATURE MEDICINE

Deep brain stimulation, histone deacetylase inhibitors and glutamatergic drugs rescue resistance to fear extinction in a genetic mouse model

(2012) Nigel Whittle et al.   NEUROPHARMACOLOGY

Clinical and Biomarker Changes in Dominantly Inherited Alzheimer's Disease

(2012) Randall J. Bateman et al.   NEW ENGLAND JOURNAL OF MEDICINE

DNA methylation in repetitive elements and post-traumatic stress disorder: a case–control study of US military service members

(2012) Jennifer A Rusiecki et al.   Epigenomics

Intracellular Trafficking of Histone Deacetylase 4 Regulates Long-Term Memory Formation

(2011) Wen-Han Wang et al.   Anatomical Record-Advances in Integrative Anatomy and Evolutionary Biology

Posttraining systemic administration of the histone deacetylase inhibitor sodium butyrate ameliorates aging-related memory decline in rats

(2011) Gustavo K. Reolon et al.   BEHAVIOURAL BRAIN RESEARCH

Twenty years of Alzheimer’s disease-causing mutations

(2011) Alison Goate et al.   JOURNAL OF NEUROCHEMISTRY

HDAC3 Is a Critical Negative Regulator of Long-Term Memory Formation

(2011) S. C. McQuown et al.   JOURNAL OF NEUROSCIENCE

Hippocampal Focal Knockout of CBP Affects Specific Histone Modifications, Long-Term Potentiation and Long-Term Memory

(2011) Ruth M Barrett et al.   NEUROPSYCHOPHARMACOLOGY

Haploinsufficiency of HDAC4 Causes Brachydactyly Mental Retardation Syndrome, with Brachydactyly Type E, Developmental Delays, and Behavioral Problems

(2010) Stephen R. Williams et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Posttraumatic Stress Disorder and Risk of Dementia Among US Veterans

(2010) Kristine Yaffe et al.   ARCHIVES OF GENERAL PSYCHIATRY

Tuning acetylation levels with HAT activators: Therapeutic strategy in neurodegenerative diseases

(2010) B. Ruthrotha Selvi et al.   Biochimica et Biophysica Acta-Gene Regulatory Mechanisms

Phenylbutyrate rescues dendritic spine loss associated with memory deficits in a mouse model of Alzheimer disease

(2010) Ana Ricobaraza et al.   HIPPOCAMPUS

CREB Binding Protein Is Required for Both Short-Term and Long-Term Memory Formation

(2010) G. Chen et al.   JOURNAL OF NEUROSCIENCE

Alzheimer's disease: clinical trials and drug development

(2010) Francesca Mangialasche et al.   LANCET NEUROLOGY

DNA methylation and memory formation

(2010) Jeremy J Day et al.   NATURE NEUROSCIENCE

Amyloid-β–induced neuronal dysfunction in Alzheimer's disease: from synapses toward neural networks

(2010) Jorge J Palop et al.   NATURE NEUROSCIENCE

Amygdala Transcriptome and Cellular Mechanisms Underlying Stress-Enhanced Fear Learning in a Rat Model of Posttraumatic Stress Disorder

(2010) Igor Ponomarev et al.   NEUROPSYCHOPHARMACOLOGY

Epigenetic and immune function profiles associated with posttraumatic stress disorder

(2010) M. Uddin et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Association of histone deacetylase genes with schizophrenia in Korean population

(2010) Tae Kim et al.   PSYCHIATRY RESEARCH

Altered Histone Acetylation Is Associated with Age-Dependent Memory Impairment in Mice

(2010) S. Peleg et al.   SCIENCE

Targeting the correct HDAC(s) to treat cognitive disorders

(2010) André Fischer et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

The epigenetic bottleneck of neurodegenerative and psychiatric diseases

(2009) Farahnaz Sananbenesi et al.   BIOLOGICAL CHEMISTRY

Cocaine self-administration alters the expression of chromatin-remodelling proteins; modulation by histone deacetylase inhibition

(2009) Lionel Host et al.   JOURNAL OF PSYCHOPHARMACOLOGY

HDAC2 negatively regulates memory formation and synaptic plasticity

(2009) Ji-Song Guan et al.   NATURE

Phenylbutyrate Ameliorates Cognitive Deficit and Reduces Tau Pathology in an Alzheimer's Disease Mouse Model

(2009) Ana Ricobaraza et al.   NEUROPSYCHOPHARMACOLOGY

Inhibitors of Class 1 Histone Deacetylases Reverse Contextual Memory Deficits in a Mouse Model of Alzheimer's Disease

(2009) Mark Kilgore et al.   NEUROPSYCHOPHARMACOLOGY

Epigenetic targets of HDAC inhibition in neurodegenerative and psychiatric disorders

(2008) T ABEL et al.   CURRENT OPINION IN PHARMACOLOGY

The histone deacetylase inhibitor valproic acid enhances acquisition, extinction, and reconsolidation of conditioned fear

(2008) T. W. Bredy et al.   LEARNING & MEMORY

Histone deacetylase inhibitors improve learning consolidation in young and in KA-induced-neurodegeneration and SAMP-8-mutant mice

(2008) Ángela Fontán-Lozano et al.   MOLECULAR AND CELLULAR NEUROSCIENCE