Epigenomics, gestational programming and risk of metabolic syndrome

Maternal obesity and high-fat diet program offspring metabolic syndrome

(2014) Mina Desai et al.   AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY

Prevalence of Childhood and Adult Obesity in the United States, 2011-2012

(2014) Cynthia L. Ogden et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Hypothalamic miR-103 Protects from Hyperphagic Obesity in Mice

(2014) I. A. Vinnikov et al.   JOURNAL OF NEUROSCIENCE

Effects of hypoxic exercise training on microRNA expression and lipid metabolism in obese rat livers

(2014) Ying-li Lu et al.   Journal of Zhejiang University-SCIENCE B

A Long Noncoding RNA Transcriptional Regulatory Circuit Drives Thermogenic Adipocyte Differentiation

(2014) Xu-Yun Zhao et al.   MOLECULAR CELL

The RNA World: molecular cooperation at the origins of life

(2014) Paul G. Higgs et al.   NATURE REVIEWS GENETICS

In utero undernourishment perturbs the adult sperm methylome and intergenerational metabolism

(2014) E. J. Radford et al.   SCIENCE

Paternal transgenerational glucose intolerance with epigenetic alterations in second generation offspring of GDM

(2013) Guo-Lian Ding et al.   ASIAN JOURNAL OF ANDROLOGY

Transgenerational effects of prenatal exposure to the 1944-45 Dutch famine

(2013) MVE Veenendaal et al.   BJOG-AN INTERNATIONAL JOURNAL OF OBSTETRICS AND GYNAECOLOGY

Paternal obesity is associated with IGF2hypomethylation in newborns: results from a Newborn Epigenetics Study (NEST) cohort

(2013) Adelheid Soubry et al.   BMC Medicine

Developmental Programming of Offspring Obesity, Adipogenesis, and Appetite

(2013) MICHAEL G. ROSS et al.   CLINICAL OBSTETRICS AND GYNECOLOGY

Maternal Obesity Induces Epigenetic Modifications to Facilitate Zfp423 Expression and Enhance Adipogenic Differentiation in Fetal Mice

(2013) Q.-Y. Yang et al.   DIABETES

Maternal Obesity Enhances White Adipose Tissue Differentiation and Alters Genome-Scale DNA Methylation in Male Rat Offspring

(2013) Sarah J. Borengasser et al.   ENDOCRINOLOGY

High folate gestational and post-weaning diets alter hypothalamic feeding pathways by DNA methylation in Wistar rat offspring

(2013) Clara E. Cho et al.   Epigenetics

Differential DNA methylation patterns between high and low responders to a weight loss intervention in overweight or obese adolescents: the EVASYON study

(2013) Adriana Moleres et al.   FASEB JOURNAL

Prevalence and Trends of Metabolic Syndrome in the Adult U.S. Population, 1999–2010

(2013) Hiram Beltrán-Sánchez et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Differential methylation in glucoregulatory genes of offspring born before vs. after maternal gastrointestinal bypass surgery

(2013) F. Guenard et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Long noncoding RNAs regulate adipogenesis

(2013) Lei Sun et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Global differences in specific histone H3 methylation are associated with overweight and type 2 diabetes

(2013) Åsa Jufvas et al.   Clinical Epigenetics

DNA methylation age of human tissues and cell types

(2013) Steve Horvath   GENOME BIOLOGY

Epigenetic regulation of adipogenesis by histone methylation

(2012) Kai Ge   Biochimica et Biophysica Acta-Gene Regulatory Mechanisms

Maternal weight gain during the first half of pregnancy and offspring obesity at 16 years: a prospective cohort study

(2012) J Laitinen et al.   BJOG-AN INTERNATIONAL JOURNAL OF OBSTETRICS AND GYNAECOLOGY

Developmental Origins of Obesity: Programmed Adipogenesis

(2012) Mina Desai et al.   Current Diabetes Reports

Epigenetic regulation of adipogenesis

(2012) Melina M. Musri et al.   CURRENT OPINION IN CLINICAL NUTRITION AND METABOLIC CARE

Global profiling of DNA methylation erasure in mouse primordial germ cells

(2012) S. Guibert et al.   GENOME RESEARCH

Inflammatory markers and bariatric surgery: a meta-analysis

(2012) S. Raghavendra Rao   INFLAMMATION RESEARCH

Prevalence of Obesity and Trends in Body Mass Index Among US Children and Adolescents, 1999-2010

(2012) Cynthia L. Ogden et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Prevalence of Obesity and Trends in the Distribution of Body Mass Index Among US Adults, 1999-2010

(2012) Katherine M. Flegal et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

DNA methylation in metabolic disorders

(2011) Romain Barres et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

Epigenetics: a possible role in acute and transgenerational regulation of dairy cow milk production

(2011) K. Singh et al.   Animal

Nutrition, Epigenetics, and Metabolic Syndrome

(2011) Junjun Wang et al.   ANTIOXIDANTS & REDOX SIGNALING

Obesity related methylation changes in DNA of peripheral blood leukocytes

(2011) Xiaoling Wang et al.   BMC Medicine

Cancerous miRNAs and their regulation

(2011) Xu-Bao Shi et al.   CELL CYCLE

microRNAs in the Regulation of Adipogenesis and Obesity

(2011) R. A. McGregor et al.   CURRENT MOLECULAR MEDICINE

Epigenetic Gene Promoter Methylation at Birth Is Associated With Child's Later Adiposity

(2011) K. M. Godfrey et al.   DIABETES

Maternal High-Fat Diet Effects on Third-Generation Female Body Size via the Paternal Lineage

(2011) Gregory A. Dunn et al.   ENDOCRINOLOGY

Environmental epigenetic transgenerational inheritance and somatic epigenetic mitotic stability

(2011)   Epigenetics

Intergenerational change and familial aggregation of body mass index

(2011) Paul C. D. Johnson et al.   EUROPEAN JOURNAL OF EPIDEMIOLOGY

Environmental regulation of the neural epigenome

(2011) Christian Caldji et al.   FEBS LETTERS

High birth weight and obesity—a vicious circle across generations

(2011) S Cnattingius et al.   INTERNATIONAL JOURNAL OF OBESITY

Epigenetic regulation in obesity

(2011) C Lavebratt et al.   INTERNATIONAL JOURNAL OF OBESITY

Genetic variation near IRS1 associates with reduced adiposity and an impaired metabolic profile

(2011) Tuomas O Kilpeläinen et al.   NATURE GENETICS

Neuronal activity modifies the DNA methylation landscape in the adult brain

(2011) Junjie U Guo et al.   NATURE NEUROSCIENCE

Changes in Whole Blood Gene Expression in Obese Subjects with Type 2 Diabetes Following Bariatric Surgery: a Pilot Study

(2011) Stela Z. Berisha et al.   PLoS One

Allele-Specific, Age-Dependent and BMI-Associated DNA Methylation of Human MCHR1

(2011) Stefanie Stepanow et al.   PLoS One

Fasting and High-Fat Diet Alter Histone Deacetylase Expression in the Medial Hypothalamus

(2011) Hiromasa Funato et al.   PLoS One

Progressive, Transgenerational Changes in Offspring Phenotype and Epigenotype following Nutritional Transition

(2011) Graham C. Burdge et al.   PLoS One

Fetal Programming of Adipose Tissue: Effects of Intrauterine Growth Restriction and Maternal Obesity/High-Fat Diet

(2011) Mina Desai et al.   SEMINARS IN REPRODUCTIVE MEDICINE

Nuclear receptor coregulators merge transcriptional coregulation with epigenetic regulation

(2011) Shigeaki Kato et al.   TRENDS IN BIOCHEMICAL SCIENCES

Epigenetic regulation by nuclear receptors

(2011) Christopher D Green et al.   Epigenomics

Epigenetics of programmed obesity: alteration in IUGR rat hepatic IGF1 mRNA expression and histone structure in rapid vs. delayed postnatal catch-up growth

(2010) Darran N. Tosh et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

What an epigenome remembers

(2010) Ulrike C. Lange et al.   BIOESSAYS

Insulin promoter DNA methylation correlates negatively with insulin gene expression and positively with HbA1c levels in human pancreatic islets

(2010) B. T. Yang et al.   DIABETOLOGIA

Epigenetic Changes in the Hypothalamic Proopiomelanocortin and Glucocorticoid Receptor Genes in the Ovine Fetus after Periconceptional Undernutrition

(2010) Adam Stevens et al.   ENDOCRINOLOGY

Maternal High-Fat Diet Alters Methylation and Gene Expression of Dopamine and Opioid-Related Genes

(2010) Zivjena Vucetic et al.   ENDOCRINOLOGY

Transgenerational Inheritance of Glucose Intolerance in a Mouse Model of Neonatal Overnutrition

(2010) Thais Pentinat et al.   ENDOCRINOLOGY

Epigenetic changes in early life and future risk of obesity

(2010) K A Lillycrop et al.   INTERNATIONAL JOURNAL OF OBESITY

Epigenetic regulation of adipocyte differentiation and adipogenesis

(2010) Hong-xing Li et al.   Journal of Zhejiang University-SCIENCE B

Maternal Gestational Weight Gain and Offspring Weight in Adolescence

(2010) Emily Oken et al.   OBSTETRICS AND GYNECOLOGY

MiRNA Expression Profile of Human Subcutaneous Adipose and during Adipocyte Differentiation

(2010) Francisco J. Ortega et al.   PLoS One

Perinatal exposure of rats to Bisphenol A affects fertility of male offspring—An overview

(2010) Smita Salian et al.   REPRODUCTIVE TOXICOLOGY

Bigger babies born to women survivors of the 1959–1961 Chinese famine: a puzzle due to survival selection?

(2010) C. Huang et al.   Journal of Developmental Origins of Health and Disease

Differential epigenomic and transcriptomic responses in subcutaneous adipose tissue between low and high responders to caloric restriction

(2009) Luigi Bouchard et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

Forced catch-up growth after fetal protein restriction alters the adipose tissue gene expression program leading to obesity in adult mice

(2009) V. V. Bol et al.   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

Maternal obesity is necessary for programming effect of high-fat diet on offspring

(2009) Christy L. White et al.   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

Growth and chronic disease: findings in the Helsinki Birth Cohort

(2009) David J. P. Barker et al.   ANNALS OF HUMAN BIOLOGY

CpG island methylation pattern in different human tissues and its correlation with gene expression

(2009) Shicai Fan et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Expression of the peroxisome proliferator activated receptor gamma gene is repressed by DNA methylation in visceral adipose tissue of mouse models of diabetes

(2009) Katsunori Fujiki et al.   BMC BIOLOGY

Estrogen Regulation of MicroRNA Expression

(2009) Carolyn Klinge   CURRENT GENOMICS

Obesity and metabolic syndrome in histone demethylase JHDM2a-deficient mice

(2009) Takeshi Inagaki et al.   GENES TO CELLS

DNA methylation differences after exposure to prenatal famine are common and timing- and sex-specific

(2009) Elmar W. Tobi et al.   HUMAN MOLECULAR GENETICS

The role of GNAS and other imprinted genes in the development of obesity

(2009) L S Weinstein et al.   INTERNATIONAL JOURNAL OF OBESITY

Effects of Maternal Surgical Weight Loss in Mothers on Intergenerational Transmission of Obesity

(2009) J. Smith et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Non-coding RNAs: regulators of disease

(2009) Ryan J Taft et al.   JOURNAL OF PATHOLOGY

High fat diet-induced obesity modifies the methylation pattern of leptin promoter in rats

(2009) F. I. Milagro et al.   JOURNAL OF PHYSIOLOGY AND BIOCHEMISTRY

Hypothalamic proopiomelanocortin promoter methylation becomes altered by early overfeeding: an epigenetic model of obesity and the metabolic syndrome

(2009) Andreas Plagemann et al.   JOURNAL OF PHYSIOLOGY-LONDON

Imprinting and epigenetic changes in the early embryo

(2009) Jamie R. Weaver et al.   MAMMALIAN GENOME

Epigenetics in spermatogenesis

(2009) Jacquetta M. Trasler   MOLECULAR AND CELLULAR ENDOCRINOLOGY

An Architectural Role for a Nuclear Noncoding RNA: NEAT1 RNA Is Essential for the Structure of Paraspeckles

(2009) Christine M. Clemson et al.   MOLECULAR CELL

Role of Jhdm2a in regulating metabolic gene expression and obesity resistance

(2009) Keisuke Tateishi et al.   NATURE

Human DNA methylomes at base resolution show widespread epigenomic differences

(2009) Ryan Lister et al.   NATURE

Increased Expression of DNA Methyltransferase 3a in Obese Adipose Tissue: Studies With Transgenic Mice

(2009) Yasutomi Kamei et al.   Obesity

Transgenerational effects of prenatal exposure to the Dutch famine on neonatal adiposity and health in later life

(2008) RC Painter et al.   BJOG-AN INTERNATIONAL JOURNAL OF OBSTETRICS AND GYNAECOLOGY

Protein restriction during gestation and/or lactation causes adverse transgenerational effects on biometry and glucose metabolism in F1 and F2 progenies of rats

(2008) Alessandra R. Pinheiro et al.   CLINICAL SCIENCE

Intergenerational Transmission of Glucose Intolerance and Obesity by In Utero Undernutrition in Mice

(2008) J. C. Jimenez-Chillaron et al.   DIABETES

Environmental epigenomics in human health and disease

(2008) Dana C. Dolinoy et al.   ENVIRONMENTAL AND MOLECULAR MUTAGENESIS

Developmental exposure to bisphenol A increases prostate cancer susceptibility in adult rats: epigenetic mode of action is implicated

(2008) Gail S. Prins et al.   FERTILITY AND STERILITY

Inflammatory signalling as mediator of epigenetic modulation in tissue-specific chronic inflammation

(2008) Liselotte Bäckdahl et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Histone Code Modifications Repress Glucose Transporter 4 Expression in the Intrauterine Growth-restricted Offspring

(2008) Nupur Raychaudhuri et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Maternal nutritional history predicts obesity in adult offspring independent of postnatal diet

(2008) G. J. Howie et al.   JOURNAL OF PHYSIOLOGY-LONDON

Transgenerational Epigenetic Programming of the Brain Transcriptome and Anxiety Behavior

(2008) Michael K. Skinner et al.   PLoS One

Targeted inactivation of MLL3 histone H3-Lys-4 methyltransferase activity in the mouse reveals vital roles for MLL3 in adipogenesis

(2008) J. Lee et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Specific expression of long noncoding RNAs in the mouse brain

(2008) T. R. Mercer et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Persistent epigenetic differences associated with prenatal exposure to famine in humans

(2008) B. T. Heijmans et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Regulating the regulators: mechanisms controlling the maturation of microRNAs

(2008) Xavier C. Ding et al.   TRENDS IN BIOTECHNOLOGY

Intersection of nuclear receptors and the proteasome on the epigenetic landscape

(2007) H. Karimi Kinyamu et al.   ENVIRONMENTAL AND MOLECULAR MUTAGENESIS

What is an epigenetic transgenerational phenotype?

(2007) Michael K. Skinner   REPRODUCTIVE TOXICOLOGY