Investigation of triazole-linked indole and oxindole glycoconjugates as potential anticancer agents: novel Akt/PKB signaling pathway inhibitors

Design and synthesis of 2-oxindole based multi-targeted inhibitors of PDK1/Akt signaling pathway for the treatment of glioblastoma multiforme

(2015) Simona Sestito et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Synthesis and biological evaluation of novel Δ2-isoxazoline fused cyclopentane derivatives as potential antimicrobial and anticancer agents

(2015) Santosh Kumar Prajapti et al.   MedChemComm

Combined inhibition of AKT/mTOR and MDM2 enhances Glioblastoma Multiforme cell apoptosis and differentiation of cancer stem cells

(2015) Simona Daniele et al.   Scientific Reports

Synthesis of new class of spirocarbocycle derivatives by multicomponent domino reaction and their evaluation for antimicrobial, anticancer activity and molecular docking studies

(2014) N. Sudhapriya et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Structural optimization of indole based compounds for highly promising anti-cancer activities: Structure activity relationship studies and identification of lead molecules

(2014) Shaveta et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

An expedient synthesis of 3-alkylideneoxindoles by Ti(OiPr)4/pyridine-mediated Knoevenagel condensation

(2014) Hyun Ju Lee et al.   TETRAHEDRON LETTERS

Mechanisms of G1 cell cycle arrest and apoptosis in myeloma cells induced by hybrid-compound histone deacetylase inhibitor

(2013) Seiko Fujii et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Substituted indolin-2-ones as p90 ribosomal S6 protein kinase 2 (RSK2) inhibitors: Molecular docking simulation and structure–activity relationship analysis

(2013) Ye Zhong et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Chemistry and Biology of Indoles and Indazoles: A Mini-Review

(2013) Nasir Shafakat Ali et al.   MINI-REVIEWS IN MEDICINAL CHEMISTRY

Synthesis of Novel 3,5-Disubstituted-2-oxindole Derivatives As Antitumor Agents against Human Nonsmall Cell Lung Cancer

(2013) Giulia Nesi et al.   ACS Medicinal Chemistry Letters

Catalytic asymmetric synthesis of 3-hydroxyoxindole: a potentially bioactive molecule

(2012) Akshay Kumar et al.   RSC Advances

Ubiquitin carboxyl-terminal hydrolase 1 (UCHL1) is a potential tumour suppressor in prostate cancer and is frequently silenced by promoter methylation

(2011) Ramesh Ummanni et al.   Molecular Cancer

3-Alkenyl-oxindoles: Natural Products, Pharmaceuticals, and Recent Synthetic Advances in Tandem/Telescoped Approaches

(2010) Alessia Millemaggi et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Promise and challenges in drug discovery and development of hybrid anticancer drugs

(2009) Lalji K Gediya et al.   Expert Opinion on Drug Discovery

Highly Enantioselective and Organocatalytic α-Amination of 2-Oxindoles

(2009) Liang Cheng et al.   ORGANIC LETTERS

Functionalized 3-benzylidene-indolin-2-ones: Inducers of NAD(P)H-quinone oxidoreductase 1 (NQO1) with antiproliferative activity

(2008) Wei Zhang et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Application of Ball Milling Technology to Carbohydrate Reactions‐II. Solvent‐Free Mechanochemical Synthesis of Glycosyl Azides‡

(2008) G. Mugunthan et al.   JOURNAL OF CARBOHYDRATE CHEMISTRY