Design and synthesis of 2-oxindole based multi-targeted inhibitors of PDK1/Akt signaling pathway for the treatment of glioblastoma multiforme

Published 2015 View Full Article

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Title
Design and synthesis of 2-oxindole based multi-targeted inhibitors of PDK1/Akt signaling pathway for the treatment of glioblastoma multiforme
Authors
Keywords
PDK1 inhibitors, Kinase inhibitors, Oxindole derivatives, Glioblastoma, GBM stem cells, Multi-target therapy
Journal
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
Volume 105, Issue -, Pages 274-288
Publisher
Elsevier BV
Online
2015-10-25
DOI
10.1016/j.ejmech.2015.10.020

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