Synthesis and biological evaluation of novel Δ2-isoxazoline fused cyclopentane derivatives as potential antimicrobial and anticancer agents

Piperlongumine, an alkaloid causes inhibition of PI3 K/Akt/mTOR signaling axis to induce caspase-dependent apoptosis in human triple-negative breast cancer cells

(2014) Shweta Shrivastava et al.   APOPTOSIS

Isoxazoline containing natural products as anticancer agents: A review

(2014) Kamalneet Kaur et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

4,5,6,7-Tetrahydro-isoxazolo-[4,5-c]-pyridines as a new class of cytotoxic Hsp90 inhibitors

(2014) Riccardo Baruchello et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Use of JC-1 to assess mitochondrial membrane potential in sea urchin sperm

(2014) M.T. Binet et al.   JOURNAL OF EXPERIMENTAL MARINE BIOLOGY AND ECOLOGY

Probing functional diversity in pactamycin toward antibiotic, antitumor, and antiprotozoal activity

(2013) Stephen Hanessian et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Synthesis of new chromeno-annulated cis-fused pyrano[4,3-c]isoxazole derivatives via intramolecular nitrone cycloaddition and their cytotoxicity evaluation

(2013) Naveen Kumar Bejjanki et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Anti-inflammatory and apoptotic effects of the polyphenol curcumin on human fibroblast-like synoviocytes

(2013) Burkhard Kloesch et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Luteolin exerts anti-tumor activity through the suppression of epidermal growth factor receptor-mediated pathway in MDA-MB-231 ER-negative breast cancer cells

(2012) Eun-Ju Lee et al.   FOOD AND CHEMICAL TOXICOLOGY

Isoxazoles incorporated N-substituted decahydroquinolines: A precursor to the next generation antimicrobial drug

(2011) Mariappan Babu et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Synthesis and biological evaluation of cyclopentane-linked alkyl phosphocholines as potential anticancer agents that act by inhibiting Akt phosphorylation

(2011) Md. Maqusood Alam et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Synthesis and Biochemical Evaluation of Δ2-Isoxazoline Derivatives as DNA Methyltransferase 1 Inhibitors

(2011) Sabrina Castellano et al.   JOURNAL OF MEDICINAL CHEMISTRY

Discovery of Isoxazole Analogues of Sazetidine-A as Selective α4β2-Nicotinic Acetylcholine Receptor Partial Agonists for the Treatment of Depression

(2011) Jianhua Liu et al.   JOURNAL OF MEDICINAL CHEMISTRY

Design, synthesis and biological evaluation of 3,5-diaryl-isoxazoline/isoxazole-pyrrolobenzodiazepine conjugates as potential anticancer agents

(2010) Ahmed Kamal et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Synthesis, biological evaluation and molecular docking of novel series of spiro [(2H,3H) quinazoline-2,1′- cyclohexan]-4(1H)- one derivatives as anti-inflammatory and analgesic agents

(2010) K.M. Amin et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Synthesis and biological evaluation of 3,5-diaryl isoxazoline/isoxazole linked 2,3-dihydroquinazolinone hybrids as anticancer agents

(2010) Ahmed Kamal et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Structure of DNMT1-DNA Complex Reveals a Role for Autoinhibition in Maintenance DNA Methylation

(2010) J. Song et al.   SCIENCE

New cyclopentane derivatives as inhibitors of steroid metabolizing enzymes AKR1C1 and AKR1C3

(2009) Bogdan Štefane et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Microbial drug discovery: 80 years of progress

(2009) Arnold L Demain et al.   JOURNAL OF ANTIBIOTICS

A tryptophan-analog host whose interactions with ammonium ions in water are dominated by the hydrophobic effect

(2009) Amanda L. Whiting et al.   TETRAHEDRON LETTERS

Physicochemical and biological characterization of novel macrocycles derived from o-phthalaldehyde

(2008) P. Muralidhar Reddy et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY