Genetically modified (GM) crops: milestones and new advances in crop improvement

Programmable editing of a target base in genomic DNA without double-stranded DNA cleavage

(2016) Alexis C. Komor et al.   NATURE

Improving nutritional quality and fungal tolerance in soya bean and grass pea by expressing an oxalate decarboxylase

(2016) Vinay Kumar et al.   PLANT BIOTECHNOLOGY JOURNAL

Fruit Ripening Regulation of α-Mannosidase Expression by the MADS Box Transcription Factor RIPENING INHIBITOR and Ethylene

(2016) Mohammad Irfan et al.   Frontiers in Plant Science

Cpf1 Is a Single RNA-Guided Endonuclease of a Class 2 CRISPR-Cas System

(2015) Bernd Zetsche et al.   CELL

Development of plants resistant to tomato geminiviruses using artificial trans-acting small interfering RNA

(2015) Archana Singh et al.   MOLECULAR PLANT PATHOLOGY

A calmodulin like EF hand protein positively regulates oxalate decarboxylase expression by interacting with E-box elements of the promoter

(2015) Ayushi Kamthan et al.   Scientific Reports

Small RNAs in plants: recent development and application for crop improvement

(2015) Ayushi Kamthan et al.   Frontiers in Plant Science

Establishing a CRISPR–Cas-like immune system conferring DNA virus resistance in plants

(2015) Xiang Ji et al.   Nature Plants

Conferring resistance to geminiviruses with the CRISPR–Cas prokaryotic immune system

(2015) Nicholas J. Baltes et al.   Nature Plants

Association of dengue virus infection susceptibility with polymorphisms of 2′-5′-oligoadenylate synthetase genes: a case–control study

(2014) Ramanathan Thamizhmani et al.   Brazilian Journal of Infectious Diseases

Insights into transcriptional regulation of  -D-N-acetylhexosaminidase, an N-glycan-processing enzyme involved in ripening-associated fruit softening

(2014) M. Irfan et al.   JOURNAL OF EXPERIMENTAL BOTANY

Single-Domain Antibodies Targeting Neuraminidase Protect against an H5N1 Influenza Virus Challenge

(2014) F. M. Cardoso et al.   JOURNAL OF VIROLOGY

The movement protein (NSm) ofTomato spotted wilt virusis the avirulence determinant in the tomatoSw-5gene-based resistance

(2014) Ana Peiró et al.   MOLECULAR PLANT PATHOLOGY

Simultaneous editing of three homoeoalleles in hexaploid bread wheat confers heritable resistance to powdery mildew

(2014) Yanpeng Wang et al.   NATURE BIOTECHNOLOGY

RNA-guided transcriptional regulationin plantavia synthetic dCas9-based transcription factors

(2014) Agnieszka Piatek et al.   PLANT BIOTECHNOLOGY JOURNAL

The CRISPR/Cas9 system produces specific and homozygous targeted gene editing in rice in one generation

(2014) Hui Zhang et al.   PLANT BIOTECHNOLOGY JOURNAL

Improved soybean oil quality by targeted mutagenesis of the fatty acid desaturase 2 gene family

(2014) William Haun et al.   PLANT BIOTECHNOLOGY JOURNAL

Targeted Genome Editing of Sweet Orange Using Cas9/sgRNA

(2014) Hongge Jia et al.   PLoS One

Multigeneration analysis reveals the inheritance, specificity, and patterns of CRISPR/Cas-induced gene modifications in Arabidopsis

(2014) Z. Feng et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Coordinated regulation of photosynthesis in rice increases yield and tolerance to environmental stress

(2014) Madana M. R. Ambavaram et al.   Nature Communications

Efficient genome editing in plants using a CRISPR/Cas system

(2013) Zhengyan Feng et al.   CELL RESEARCH

Targeted Mutagenesis in Zea mays Using TALENs and the CRISPR/Cas System

(2013) Zhen Liang et al.   Journal of Genetics and Genomics

RNA-Guided Genome Editing in Plants Using a CRISPR–Cas System

(2013) Kabin Xie et al.   Molecular Plant

Multiplex and homologous recombination–mediated genome editing in Arabidopsis and Nicotiana benthamiana using guide RNA and Cas9

(2013) Jian-Feng Li et al.   NATURE BIOTECHNOLOGY

Insect resistance to Bt crops: lessons from the first billion acres

(2013) Bruce E Tabashnik et al.   NATURE BIOTECHNOLOGY

Targeted mutagenesis in the model plant Nicotiana benthamiana using Cas9 RNA-guided endonuclease

(2013) Vladimir Nekrasov et al.   NATURE BIOTECHNOLOGY

Targeted genome modification of crop plants using a CRISPR-Cas system

(2013) Qiwei Shan et al.   NATURE BIOTECHNOLOGY

Demonstration of CRISPR/Cas9/sgRNA-mediated targeted gene modification in Arabidopsis, tobacco, sorghum and rice

(2013) Wenzhi Jiang et al.   NUCLEIC ACIDS RESEARCH

Male-sterile maize plants produced by targeted mutagenesis of the cytochrome P450-like gene (MS26) using a re-designed I-CreI homing endonuclease

(2013) Vesna Djukanovic et al.   PLANT JOURNAL

TAL effector nucleases induce mutations at a pre-selected location in the genome of primary barley transformants

(2013) Toni Wendt et al.   PLANT MOLECULAR BIOLOGY

RNA-Guided Genome Editing for Target Gene Mutations in Wheat

(2013) Santosh Kumar Upadhyay et al.   G3-Genes Genomes Genetics

Down-regulation of POLYGALACTURONASE1 alters firmness, tensile strength and water loss in apple (Malus x domestica) fruit

(2012) Ross G Atkinson et al.   BMC PLANT BIOLOGY

Obligate Ligation-Gated Recombination (ObLiGaRe): Custom-designed nuclease-mediated targeted integration through nonhomologous end joining

(2012) M. Maresca et al.   GENOME RESEARCH

Widespread adoption of Bt cotton and insecticide decrease promotes biocontrol services

(2012) Yanhui Lu et al.   NATURE

Plant disease resistance genes: Current status and future directions

(2012) Mayank Anand Gururani et al.   PHYSIOLOGICAL AND MOLECULAR PLANT PATHOLOGY

Overexpression of Arabidopsis and Rice stress genes’ inducible transcription factor confers drought and salinity tolerance to rice

(2012) Karabi Datta et al.   PLANT BIOTECHNOLOGY JOURNAL

Tuber-specific silencing of asparagine synthetase-1 reduces the acrylamide-forming potential of potatoes grown in the field without affecting tuber shape and yield

(2012) Rekha Chawla et al.   PLANT BIOTECHNOLOGY JOURNAL

The wheat chloroplastic small heat shock protein (sHSP26) is involved in seed maturation and germination and imparts tolerance to heat stress

(2012) HARSH CHAUHAN et al.   PLANT CELL AND ENVIRONMENT

Isolation and functional characterisation of banana phytoene synthase genes as potential cisgenes

(2012) Bulukani Mlalazi et al.   PLANTA

OsLEA3-2, an Abiotic Stress Induced Gene of Rice Plays a Key Role in Salt and Drought Tolerance

(2012) Jianli Duan et al.   PLoS One

Expression of a fungal sterol desaturase improves tomato drought tolerance, pathogen resistance and nutritional quality

(2012) Ayushi Kamthan et al.   Scientific Reports

SEPALLATA1/2-suppressed mature apples have low ethylene, high auxin and reduced transcription of ripening-related genes

(2012) Robert J. Schaffer et al.   AoB Plants

Genome Engineering With Zinc-Finger Nucleases

(2011) Dana Carroll   GENETICS

Grapevines engineered to express cisgenic Vitis vinifera thaumatin-like protein exhibit fungal disease resistance

(2011) Sadanand A. Dhekney et al.   IN VITRO CELLULAR & DEVELOPMENTAL BIOLOGY-PLANT

The development of a cisgenic apple plant

(2011) Thalia Vanblaere et al.   JOURNAL OF BIOTECHNOLOGY

Involvement of cytosolic ascorbate peroxidase and Cu/Zn-superoxide dismutase for improved tolerance against drought stress

(2011) M. Faize et al.   JOURNAL OF EXPERIMENTAL BOTANY

Role of DREBs in regulation of abiotic stress responses in plants

(2011) C. Lata et al.   JOURNAL OF EXPERIMENTAL BOTANY

Expression of the Arabidopsis AtMYB44 gene confers drought/salt-stress tolerance in transgenic soybean

(2011) Jun Sung Seo et al.   MOLECULAR BREEDING

Over-expression of a DEAD-box helicase, PDH45, confers both seedling and reproductive stage salinity tolerance to rice (Oryza sativa L.)

(2011) Mahzabin Amin et al.   MOLECULAR BREEDING

Pleiotropic Effects of the Wheat Dehydrin DHN-5 on Stress Responses in Arabidopsis

(2011) F. Brini et al.   PLANT AND CELL PHYSIOLOGY

Cisgenic barley with improved phytase activity

(2011) Inger B. Holme et al.   PLANT BIOTECHNOLOGY JOURNAL

Bacillus thuringiensis: a century of research, development and commercial applications

(2011) Georgina Sanahuja et al.   PLANT BIOTECHNOLOGY JOURNAL

C4Cycles: Past, Present, and Future Research on C4Photosynthesis

(2011) Jane A. Langdale   PLANT CELL

Functional analysis and expression profiling of HcrVf1 and HcrVf2 for development of scab resistant cisgenic and intragenic apples

(2011) Sameer G. Joshi et al.   PLANT MOLECULAR BIOLOGY

Targeted transcriptional repression using a chimeric TALE-SRDX repressor protein

(2011) Magdy M. Mahfouz et al.   PLANT MOLECULAR BIOLOGY

Targeted Mutagenesis of Duplicated Genes in Soybean with Zinc-Finger Nucleases

(2011) S. J. Curtin et al.   PLANT PHYSIOLOGY

Human Umbilical Cord Blood Cells Restore Brain Damage Induced Changes in Rat Somatosensory Cortex

(2011) Maren Geißler et al.   PLoS One

Constitutive Overexpression of the OsNAS Gene Family Reveals Single-Gene Strategies for Effective Iron- and Zinc-Biofortification of Rice Endosperm

(2011) Alexander A. T. Johnson et al.   PLoS One

TAL Effectors: Customizable Proteins for DNA Targeting

(2011) A. J. Bogdanove et al.   SCIENCE

Fruit improvement using intragenesis and artificial microRNA

(2011) Barbara Molesini et al.   TRENDS IN BIOTECHNOLOGY

Agricultural biotechnology for crop improvement in a variable climate: hope or hype?

(2011) Rajeev K. Varshney et al.   TRENDS IN PLANT SCIENCE

From genome studies to agricultural biotechnology: closing the gap between basic plant science and applied agriculture

(2010) Douglas R Cook et al.   CURRENT OPINION IN PLANT BIOLOGY

Developing stress tolerant plants through in vitro selection—An overview of the recent progress

(2010) Manoj K. Rai et al.   ENVIRONMENTAL AND EXPERIMENTAL BOTANY

Targeting DNA Double-Strand Breaks with TAL Effector Nucleases

(2010) M. Christian et al.   GENETICS

The N-glycan processing enzymes α-mannosidase and β-D-N-acetylhexosaminidase are involved in ripening-associated softening in the non-climacteric fruits of capsicum

(2010) Sumit Ghosh et al.   JOURNAL OF EXPERIMENTAL BOTANY

Peer-reviewed surveys indicate positive impact of commercialized GM crops

(2010) Janet E Carpenter   NATURE BIOTECHNOLOGY

The role of transgenic crops in sustainable development

(2010) Julian Raymond Park et al.   PLANT BIOTECHNOLOGY JOURNAL

An efficient method for the production of marker-free transgenic plants of peanut (Arachis hypogaea L.)

(2010) Madhurima Bhatnagar et al.   PLANT CELL REPORTS

Reactive oxygen species and antioxidant machinery in abiotic stress tolerance in crop plants

(2010) Sarvajeet Singh Gill et al.   PLANT PHYSIOLOGY AND BIOCHEMISTRY

Enhancement of fruit shelf life by suppressing N-glycan processing enzymes

(2010) V. S. Meli et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

High frequency targeted mutagenesis in Arabidopsis thaliana using zinc finger nucleases

(2010) F. Zhang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Next-generation protein-rich potato expressing the seed protein geneAmA1is a result of proteome rebalancing in transgenic tuber

(2010) Subhra Chakraborty et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Ripening of fleshy fruit: Molecular insight and the role of ethylene

(2009) Vishwas A. Bapat et al.   BIOTECHNOLOGY ADVANCES

Biology and genetic engineering of fruit maturation for enhanced quality and shelf-life

(2009) Antonio J Matas et al.   CURRENT OPINION IN BIOTECHNOLOGY

Cisgenesis: an important sub-invention for traditional plant breeding companies

(2009) E. Jacobsen et al.   EUPHYTICA

First transgenic geminivirus-resistant plant in the field

(2009) Francisco J L Aragão et al.   NATURE BIOTECHNOLOGY

Heritable targeted mutagenesis in maize using a designed endonuclease

(2009) Huirong Gao et al.   PLANT JOURNAL

Antisense Down-Regulation of the FaPG1 Gene Reveals an Unexpected Central Role for Polygalacturonase in Strawberry Fruit Softening

(2009) M. A. Quesada et al.   PLANT PHYSIOLOGY

Auto-excision of selectable marker genes from transgenic tobacco via a stress inducible FLP/FRT site-specific recombination system

(2009) Hee-Jong Woo et al.   TRANSGENIC RESEARCH

NB-LRRs work a “bait and switch” on pathogens

(2009) Sarah M. Collier et al.   TRENDS IN PLANT SCIENCE

Applied Biotechnology to Combat Late Blight in Potato Caused by Phytophthora Infestans

(2009) A. J. Haverkort et al.   POTATO RESEARCH

Engineering with Precision: Tools for the New Generation of Transgenic Crops

(2008) Lorena Moeller et al.   BIOSCIENCE

Using C4 photosynthesis to increase the yield of rice—rationale and feasibility

(2008) Julian M Hibberd et al.   CURRENT OPINION IN PLANT BIOLOGY

What are the prospects for genetically engineered, disease resistant plants?

(2008) David B. Collinge et al.   EUROPEAN JOURNAL OF PLANT PATHOLOGY

A transgenic durum wheat line that is free of marker genes and expresses 1Dy10

(2008) Agata Gadaleta et al.   JOURNAL OF CEREAL SCIENCE

Artificial MicroRNAs Highly Accessible to Targets Confer Efficient Virus Resistance in Plants

(2008) C.-G. Duan et al.   JOURNAL OF VIROLOGY

Pyramiding Xa23 and Rxo1 for resistance to two bacterial diseases into an elite indica rice variety using molecular approaches

(2008) Yong-Li Zhou et al.   MOLECULAR BREEDING

Low-acrylamide French fries and potato chips

(2008) Caius M. Rommens et al.   PLANT BIOTECHNOLOGY JOURNAL

Enhanced heat and drought tolerance in transgenic rice seedlings overexpressing OsWRKY11 under the control of HSP101 promoter

(2008) Xiaolan Wu et al.   PLANT CELL REPORTS

Regulating the Regulators: The Future Prospects for Transcription-Factor-Based Agricultural Biotechnology Products

(2008) K. Century et al.   PLANT PHYSIOLOGY

Alfalfa benefits from Medicago truncatula: The RCT1 gene from M. truncatula confers broad-spectrum resistance to anthracnose in alfalfa

(2008) S. Yang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cisgenesis and intragenesis, sisters in innovative plant breeding

(2008) Henk J. Schouten et al.   TRENDS IN PLANT SCIENCE

Alleviating peanut allergy using genetic engineering: the silencing of the immunodominant allergen Ara h 2 leads to its significant reduction and a decrease in peanut allergenicity

(2007) Hortense W. Dodo et al.   PLANT BIOTECHNOLOGY JOURNAL