An Integrated Data Driven Approach to Drug Repositioning Using Gene-Disease Associations

Mining integrated semantic networks for drug repositioning opportunities

(2016) Joseph Mullen et al.   PeerJ

Extraction of relations between genes and diseases from text and large-scale data analysis: implications for translational research

(2015) Àlex Bravo et al.   BMC BIOINFORMATICS

Current treatment options in patients with mastocytosis: status in 2015 and future perspectives

(2015) Michel Arock et al.   EUROPEAN JOURNAL OF HAEMATOLOGY

Identification of highly related references about gene-disease association

(2014) Rey-Long Liu et al.   BMC BIOINFORMATICS

Genenames.org: the HGNC resources in 2015

(2014) Kristian A. Gray et al.   NUCLEIC ACIDS RESEARCH

The Comparative Toxicogenomics Database's 10th year anniversary: update 2015

(2014) Allan Peter Davis et al.   NUCLEIC ACIDS RESEARCH

The Rat Genome Database 2015: genomic, phenotypic and environmental variations and disease

(2014) Mary Shimoyama et al.   NUCLEIC ACIDS RESEARCH

Drug repositioning for orphan genetic diseases through Conserved Anticoexpressed Gene Clusters (CAGCs)

(2013) Ivan Molineris et al.   BMC BIOINFORMATICS

Inferring drug-disease associations from integration of chemical, genomic and phenotype data using network propagation

(2013) Yu-Fen Huang et al.   BMC Medical Genomics

Phenotypic vs. Target-Based Drug Discovery for First-in-Class Medicines

(2013) D C Swinney   CLINICAL PHARMACOLOGY & THERAPEUTICS

Drug Discovery for Neglected Diseases: Molecular Target-Based and Phenotypic Approaches

(2013) Ian H. Gilbert   JOURNAL OF MEDICINAL CHEMISTRY

The ChEMBL bioactivity database: an update

(2013) A. Patrícia Bento et al.   NUCLEIC ACIDS RESEARCH

The NHGRI GWAS Catalog, a curated resource of SNP-trait associations

(2013) Danielle Welter et al.   NUCLEIC ACIDS RESEARCH

PhenoDigm: analyzing curated annotations to associate animal models with human diseases

(2013) D. Smedley et al.   Database-The Journal of Biological Databases and Curation

Chapter 15: Disease Gene Prioritization

(2013) Yana Bromberg   PLoS Computational Biology

Bayesian integration of networks without gold standards

(2012) Jochen Weile et al.   BIOINFORMATICS

Drug repositioning through incomplete bi-cliques in an integrated drug–target–disease network

(2012) Simone Daminelli et al.   Integrative Biology

Discovery of small molecule cancer drugs: Successes, challenges and opportunities

(2012) Swen Hoelder et al.   Molecular Oncology

Use of genome-wide association studies for drug repositioning

(2012) Philippe Sanseau et al.   NATURE BIOTECHNOLOGY

Recent approaches to the prioritization of candidate disease genes

(2012) Nadezhda T. Doncheva et al.   Wiley Interdisciplinary Reviews-Systems Biology and Medicine

Assessing Drug Target Association Using Semantic Linked Data

(2012) Bin Chen et al.   PLoS Computational Biology

Constructing a semantic predication gold standard from the biomedical literature

(2011) Halil Kilicoglu et al.   BMC BIOINFORMATICS

Identify drug repurposing candidates by mining the Protein Data Bank

(2011) F. Moriaud et al.   BRIEFINGS IN BIOINFORMATICS

Parameterized Algorithmics for Finding Connected Motifs in Biological Networks

(2011) N. Betzler et al.   IEEE-ACM Transactions on Computational Biology and Bioinformatics

Gene-Disease Network Analysis Reveals Functional Modules in Mendelian, Complex and Environmental Diseases

(2011) Anna Bauer-Mehren et al.   PLoS One

Mining Relational Paths in Integrated Biomedical Data

(2011) Bing He et al.   PLoS One

Systematic Drug Repositioning Based on Clinical Side-Effects

(2011) Lun Yang et al.   PLoS One

DisGeNET: a Cytoscape plugin to visualize, integrate, search and analyze gene–disease networks

(2010) Anna Bauer-Mehren et al.   BIOINFORMATICS

A side effect resource to capture phenotypic effects of drugs

(2010) Michael Kuhn et al.   Molecular Systems Biology

Efficacy of Sunitinib in Advanced Medullary Thyroid Carcinoma: Intermediate Results of Phase II THYSU

(2010) A. Ravaud et al.   ONCOLOGIST

Advances in translational bioinformatics: computational approaches for the hunting of disease genes

(2009) M. G. Kann   BRIEFINGS IN BIOINFORMATICS

Systematic Evaluation of Drug–Disease Relationships to Identify Leads for Novel Drug Uses

(2009) A P Chiang et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

Predicting new molecular targets for known drugs

(2009) Michael J. Keiser et al.   NATURE