Advances in translational bioinformatics: computational approaches for the hunting of disease genes

Structural and functional restraints in the evolution of protein families and superfamilies

(2009) Sungsam Gong et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Automated inference of molecular mechanisms of disease from amino acid substitutions

(2009) B. Li et al.   BIOINFORMATICS

A geometric approach for classification and comparison of structural variants

(2009) S. Sindi et al.   BIOINFORMATICS

Disease candidate gene identification and prioritization using protein interaction networks

(2009) Jing Chen et al.   BMC BIOINFORMATICS

Next generation tools for the annotation of human SNPs

(2009) Rachel Karchin   BRIEFINGS IN BIOINFORMATICS

Exploring the human genome with functional maps

(2009) C. Huttenhower et al.   GENOME RESEARCH

ToppGene Suite for gene list enrichment analysis and candidate gene prioritization

(2009) J. Chen et al.   NUCLEIC ACIDS RESEARCH

Quantifying dominance and deleterious effect on human disease genes

(2009) Naoki Osada et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Potential etiologic and functional implications of genome-wide association loci for human diseases and traits

(2009) L. A. Hindorff et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Biomedical Discovery Acceleration, with Applications to Craniofacial Development

(2009) Sonia M. Leach et al.   PLoS Computational Biology

Structural Variation of Chromosomes in Autism Spectrum Disorder

(2008) Christian R. Marshall et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Walking the Interactome for Prioritization of Candidate Disease Genes

(2008) Sebastian Köhler et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Intrinsically Disordered Proteins in Human Diseases: Introducing the D2 Concept

(2008) Vladimir N. Uversky et al.   Annual Review of Biophysics

Gain and loss of phosphorylation sites in human cancer

(2008) P. Radivojac et al.   BIOINFORMATICS

Polymorphisms in microRNA targets: a gold mine for molecular epidemiology

(2008) K. Chen et al.   CARCINOGENESIS

Amyloidogenesis of Natively Unfolded Proteins

(2008) Vladimir Uversky   Current Alzheimer Research

Applications of computational algorithm tools to identify functional SNPs

(2008) C. George Priya Doss et al.   FUNCTIONAL & INTEGRATIVE GENOMICS

Genetic-linkage mapping of complex hereditary disorders to a whole-genome molecular-interaction network

(2008) I. Iossifov et al.   GENOME RESEARCH

Computational prediction of the functional effects of amino acid substitutions in signal peptides using a model-based approach

(2008) Lawrence S. Hon et al.   HUMAN MUTATION

Gene Expression Signatures, Clinicopathological Features, and Individualized Therapy in Breast Cancer

(2008) Chaitanya R. Acharya   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Identifying disease-causal genes using Semantic Web-based representation of integrated genomic and phenomic knowledge

(2008) Ranga Chandra Gudivada et al.   JOURNAL OF BIOMEDICAL INFORMATICS

An Ancient Evolutionary Origin of Genes Associated with Human Genetic Diseases

(2008) T. Domazet-Loso et al.   MOLECULAR BIOLOGY AND EVOLUTION

Mapping and sequencing of structural variation from eight human genomes

(2008) Jeffrey M. Kidd et al.   NATURE

Prioritization of candidate cancer genes—an aid to oncogenomic studies

(2008) Simon J. Furney et al.   NUCLEIC ACIDS RESEARCH

Reactome knowledgebase of human biological pathways and processes

(2008) L. Matthews et al.   NUCLEIC ACIDS RESEARCH

In Silico Detection of Sequence Variations Modifying Transcriptional Regulation

(2008) Malin C. Andersen et al.   PLoS Computational Biology

Network properties of genes harboring inherited disease mutations

(2008) I. Feldman et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

An integrated approach to inferring gene-disease associations in humans

(2008) Predrag Radivojac et al.   PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS

Core Signaling Pathways in Human Pancreatic Cancers Revealed by Global Genomic Analyses

(2008) S. Jones et al.   SCIENCE

An Integrated Genomic Analysis of Human Glioblastoma Multiforme

(2008) D. W. Parsons et al.   SCIENCE

Genetic Mapping in Human Disease

(2008) D. Altshuler et al.   SCIENCE