Targeting and alteration of tight junctions by bacteria and their virulence factors such as Clostridium perfringens enterotoxin
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Title
Targeting and alteration of tight junctions by bacteria and their virulence factors such as Clostridium perfringens enterotoxin
Authors
Keywords
<em class=EmphasisTypeItalic >Clostridium perfringens</em> enterotoxin, Bacterial receptors, Intestinal barrier, Claudin targeting, Pore-forming toxin
Journal
PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY
Volume 469, Issue 1, Pages 77-90
Publisher
Springer Nature
Online
2016-11-18
DOI
10.1007/s00424-016-1902-x
References
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Note: Only part of the references are listed.- The CpAL system regulates changes of the trans-epithelial resistance of human enterocytes during Clostridium perfringens type C infection
- (2016) Porfirio Nava et al. ANAEROBE
- A Genome-wide CRISPR Screen in Toxoplasma Identifies Essential Apicomplexan Genes
- (2016) Saima M. Sidik et al. CELL
- Cryo-EM structure of aerolysin variants reveals a novel protein fold and the pore-formation process
- (2016) Ioan Iacovache et al. Nature Communications
- Examination of the effects of Campylobacter concisus zonula occludens toxin on intestinal epithelial cells and macrophages
- (2016) Vikneswari Mahendran et al. Gut Pathogens
- Structural basis for disruption of claudin assembly in tight junctions by an enterotoxin
- (2016) Takehiro Shinoda et al. Scientific Reports
- Specific binding ofClostridium perfringensenterotoxin fragment to Claudin-b and modulation of zebrafish epidermal barrier
- (2015) Jingjing Zhang et al. EXPERIMENTAL DERMATOLOGY
- Interaction of theClostridium difficileBinary Toxin CDT and Its Host Cell Receptor, Lipolysis-stimulated Lipoprotein Receptor (LSR)
- (2015) Sarah Hemmasi et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Yersinia enterocoliticaAffects Intestinal Barrier Function in the Colon
- (2015) Nina A. Hering et al. JOURNAL OF INFECTIOUS DISEASES
- Claudin-4 SPECT Imaging Allows Detection of Aplastic Lesions in a Mouse Model of Breast Cancer
- (2015) M. Mosley et al. JOURNAL OF NUCLEAR MEDICINE
- Secretory diarrhoea: mechanisms and emerging therapies
- (2015) Jay R. Thiagarajah et al. Nature Reviews Gastroenterology & Hepatology
- Clostridium perfringens Alpha-Toxin Induces Gm1a Clustering and Trka Phosphorylation in the Host Cell Membrane
- (2015) Teruhisa Takagishi et al. PLoS One
- Structural insight into tight junction disassembly by Clostridium perfringens enterotoxin
- (2015) Y. Saitoh et al. SCIENCE
- Assembly and function of claudins: Structure–function relationships based on homology models and crystal structures
- (2015) G. Krause et al. SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY
- Membrane-Binding Mechanism of Clostridium perfringens Alpha-Toxin
- (2015) Masataka Oda et al. Toxins
- A claudin 3 and claudin 4-targeted Clostridium perfringens protoxin is selectively cytotoxic to PSA-producing prostate cancer cells
- (2014) Victor Romanov et al. CANCER LETTERS
- Directed structural modification of Clostridium perfringens enterotoxin to enhance binding to claudin-5
- (2014) Jonas Protze et al. CELLULAR AND MOLECULAR LIFE SCIENCES
- Towards an understanding of the role of Clostridium perfringens toxins in human and animal disease
- (2014) Francisco A Uzal et al. Future Microbiology
- α-Haemolysin ofEscherichia coliin IBD: a potentiator of inflammatory activity in the colon
- (2014) Roland Bücker et al. GUT
- Clostridium perfringens Type A Enterotoxin Damages the Rabbit Colon
- (2014) J. P. Garcia et al. INFECTION AND IMMUNITY
- Structure of a C. perfringens Enterotoxin Mutant in Complex with a Modified Claudin-2 Extracellular Loop 2
- (2014) Tamas S. Yelland et al. JOURNAL OF MOLECULAR BIOLOGY
- Preclinical study on combined chemo- and nonviral gene therapy for sensitization of melanoma using a human TNF-alpha expressing MIDGE DNA vector
- (2014) Dennis Kobelt et al. Molecular Oncology
- Cyclical Appearance of African Trypanosomes in the Cerebrospinal Fluid: New Insights in How Trypanosomes Enter the CNS
- (2014) Stefan Mogk et al. PLoS One
- Correlation between In Vitro Cytotoxicity and In Vivo Lethal Activity in Mice of Epsilon Toxin Mutants from Clostridium perfringens
- (2014) Jonatan Dorca-Arévalo et al. PLoS One
- Crystal Structure of a Claudin Provides Insight into the Architecture of Tight Junctions
- (2014) H. Suzuki et al. SCIENCE
- Internalization ofClostridium perfringensα-toxin leads to ERK activation and is involved on its cytotoxic effect
- (2013) Laura Monturiol-Gross et al. CELLULAR MICROBIOLOGY
- Chloride channel-targeted therapy for secretory diarrheas
- (2013) Jay R Thiagarajah et al. CURRENT OPINION IN PHARMACOLOGY
- Importance of Toxin A, Toxin B, and CDT in Virulence of an Epidemic Clostridium difficile Strain
- (2013) Sarah A. Kuehne et al. JOURNAL OF INFECTIOUS DISEASES
- The inhibition of COPII trafficking is important for intestinal epithelial tight junction disruption during enteropathogenic Escherichia coli and Citrobacter rodentium infection
- (2013) Ajitha Thanabalasuriar et al. MICROBES AND INFECTION
- Role of Pore-Forming Toxins in Bacterial Infectious Diseases
- (2013) F. C. O. Los et al. MICROBIOLOGY AND MOLECULAR BIOLOGY REVIEWS
- Clostridium perfringens Beta-Toxin Induces Necrostatin-Inhibitable, Calpain-Dependent Necrosis in Primary Porcine Endothelial Cells
- (2013) Delphine Autheman et al. PLoS One
- Human Claudin-8 and -14 Are Receptors Capable of Conveying the Cytotoxic Effects of Clostridium perfringens Enterotoxin
- (2013) A. Shrestha et al. mBio
- Immunologic and chemical targeting of the tight-junction protein Claudin-6 eliminates tumorigenic human pluripotent stem cells
- (2013) Uri Ben-David et al. Nature Communications
- Creation and biochemical analysis of a broad-specific claudin binder
- (2012) Azusa Takahashi et al. BIOMATERIALS
- Molecular mechanisms of gastric epithelial cell adhesion and injection of CagA by Helicobacter pylori
- (2012) Steffen Backert et al. Cell Communication and Signaling
- Shigella Targets Epithelial Tricellular Junctions and Uses a Noncanonical Clathrin-Dependent Endocytic Pathway to Spread Between Cells
- (2012) Makoto Fukumatsu et al. Cell Host & Microbe
- Claudin-4-targeted optical imaging detects pancreatic cancer and its precursor lesions
- (2012) Albrecht Neesse et al. GUT
- Cysteine-Scanning Mutagenesis Supports the Importance of Clostridium perfringens Enterotoxin Amino Acids 80 to 106 for Membrane Insertion and Pore Formation
- (2012) Jianwu Chen et al. INFECTION AND IMMUNITY
- Epithelial Barriers in Intestinal Inflammation
- (2011) Lena J. John et al. ANTIOXIDANTS & REDOX SIGNALING
- Unexpected wide substrate specificity of C. perfringens α-toxin phospholipase C
- (2011) Patricia Urbina et al. BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES
- Novel Clostridium perfringens enterotoxin suicide gene therapy for selective treatment of claudin-3- and -4-overexpressing tumors
- (2011) W Walther et al. GENE THERAPY
- Development and Application of a Mouse Intestinal Loop Model To Study theIn VivoAction of Clostridium perfringens Enterotoxin
- (2011) Justin A. Caserta et al. INFECTION AND IMMUNITY
- Polarity-regulating Kinase Partitioning-defective 1b (PAR1b) Phosphorylates Guanine Nucleotide Exchange Factor H1 (GEF-H1) to Regulate RhoA-dependent Actin Cytoskeletal Reorganization
- (2011) Yukie Yamahashi et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Mechanism ofClostridium perfringensEnterotoxin Interaction with Claudin-3/-4 Protein Suggests Structural Modifications of the Toxin to Target Specific Claudins
- (2011) Anna Veshnyakova et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Crystal Structure ofClostridium perfringensEnterotoxin Displays Features of β-Pore-forming Toxins
- (2011) Kengo Kitadokoro et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- LSR defines cell corners for tricellular tight junction formation in epithelial cells
- (2011) S. Masuda et al. JOURNAL OF CELL SCIENCE
- Aerolysin From Aeromonas hydrophila Perturbs Tight Junction Integrity and Cell Lesion Repair in Intestinal Epithelial HT-29/B6 Cells
- (2011) Roland Bücker et al. JOURNAL OF INFECTIOUS DISEASES
- Structure of the Food-Poisoning Clostridium perfringens Enterotoxin Reveals Similarity to the Aerolysin-Like Pore-Forming Toxins
- (2011) David C. Briggs et al. JOURNAL OF MOLECULAR BIOLOGY
- Extending the Aerolysin Family: From Bacteria to Vertebrates
- (2011) Pawel Szczesny et al. PLoS One
- Lipolysis-stimulated lipoprotein receptor (LSR) is the host receptor for the binary toxin Clostridium difficile transferase (CDT)
- (2011) P. Papatheodorou et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Clostridium perfringens enterotoxin carboxy-terminal fragment is a novel tumor-homing peptide for human ovarian cancer
- (2010) Emiliano Cocco et al. BMC CANCER
- A Claudin-Targeting Molecule as an Inhibitor of Tumor Metastasis
- (2010) R. Saeki et al. JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS
- Yersinia enterocolitica induces epithelial barrier dysfunction through regional tight junction changes in colonic HT-29/B6 cell monolayers
- (2010) Nina A Hering et al. LABORATORY INVESTIGATION
- Development and Application of New Mouse Models To Study the Pathogenesis of Clostridium perfringens Type C Enterotoxemias
- (2009) F. A. Uzal et al. INFECTION AND IMMUNITY
- Identification of a Claudin-4 Residue Important for Mediating the Host Cell Binding and Action of Clostridium perfringens Enterotoxin
- (2009) S. L. Robertson et al. INFECTION AND IMMUNITY
- Molecular Determinants of the Interaction betweenClostridium perfringensEnterotoxin Fragments and Claudin-3
- (2009) Lars Winkler et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Clostridium perfringensEnterotoxin Interacts with Claudins via Electrostatic Attraction
- (2009) Jun Kimura et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Tricellulin Forms a Barrier to Macromolecules in Tricellular Tight Junctions without Affecting Ion Permeability
- (2009) Susanne M. Krug et al. MOLECULAR BIOLOGY OF THE CELL
- Recombinant CPE fused to tumor necrosis factor targets human ovarian cancer cells expressing the claudin-3 and claudin-4 receptors
- (2009) X. Yuan et al. MOLECULAR CANCER THERAPEUTICS
- The bacterial virulence factor InlC perturbs apical cell junctions and promotes cell-to-cell spread of Listeria
- (2009) Tina Rajabian et al. NATURE CELL BIOLOGY
- Clostridium perfringens Epsilon Toxin Increases the Small Intestinal Permeability in Mice and Rats
- (2009) Jorge Goldstein et al. PLoS One
- Clostridium perfringens Iota-Toxin: Structure and Function
- (2009) Jun Sakurai et al. Toxins
- Domain mapping of a claudin-4 modulator, the C-terminal region of C-terminal fragment of Clostridium perfringens enterotoxin, by site-directed mutagenesis
- (2008) Azusa Takahashi et al. BIOCHEMICAL PHARMACOLOGY
- EspF Interacts with Nucleation-Promoting Factors To Recruit Junctional Proteins into Pedestals for Pedestal Maturation and Disruption of Paracellular Permeability
- (2008) J. Peralta-Ramirez et al. INFECTION AND IMMUNITY
- Effects of Clostridium perfringens Beta-Toxin on the Rabbit Small Intestine and Colon
- (2008) J. E. Vidal et al. INFECTION AND IMMUNITY
- Noncytotoxic Clostridium perfringens Enterotoxin (CPE) Variants Localize CPE Intestinal Binding and Demonstrate a Relationship between CPE-Induced Cytotoxicity and Enterotoxicity
- (2008) J. G. Smedley et al. INFECTION AND IMMUNITY
- NetB, a New Toxin That Is Associated with Avian Necrotic Enteritis Caused by Clostridium perfringens
- (2008) Anthony L. Keyburn et al. PLoS Pathogens
- Structure and function of claudins
- (2007) Gerd Krause et al. BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES
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