Novel Clostridium perfringens enterotoxin suicide gene therapy for selective treatment of claudin-3- and -4-overexpressing tumors

Turn a diarrhoea toxin into a receptor-mediated therapy for a plethora of CLDN-4-overexpressing cancers

(2010) Qin Yao et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Claudin-4-targeting of diphtheria toxin fragment A using a C-terminal fragment of Clostridium perfringens enterotoxin

(2010) Hideki Kakutani et al.   EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS

A Claudin-Targeting Molecule as an Inhibitor of Tumor Metastasis

(2010) R. Saeki et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Gene therapy-mediated delivery of targeted cytotoxins for glioma therapeutics

(2010) M. Candolfi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Molecular Determinants of the Interaction betweenClostridium perfringensEnterotoxin Fragments and Claudin-3

(2009) Lars Winkler et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Recombinant CPE fused to tumor necrosis factor targets human ovarian cancer cells expressing the claudin-3 and claudin-4 receptors

(2009) X. Yuan et al.   MOLECULAR CANCER THERAPEUTICS

A Novel Tumor-Targeted Therapy Using a Claudin-4-Targeting Molecule

(2009) R. Saeki et al.   MOLECULAR PHARMACOLOGY

Pyroptosis: host cell death and inflammation

(2009) Tessa Bergsbaken et al.   NATURE REVIEWS MICROBIOLOGY

Novel Jet-Injection Technology for Nonviral Intratumoral Gene Transfer in Patients with Melanoma and Breast Cancer

(2008) W. Walther et al.   CLINICAL CANCER RESEARCH