Directed structural modification of Clostridium perfringens enterotoxin to enhance binding to claudin-5

Claudin-3 and Claudin-5 Protein Folding and Assembly into the Tight Junction Are Controlled by Non-conserved Residues in the Transmembrane 3 (TM3) and Extracellular Loop 2 (ECL2) Segments

(2014) Jan Rossa et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Crystal Structure of a Claudin Provides Insight into the Architecture of Tight Junctions

(2014) H. Suzuki et al.   SCIENCE

Phylogenetic revision of the claudin gene family

(2013) David A. Baltzegar et al.   Marine Genomics

Creation and biochemical analysis of a broad-specific claudin binder

(2012) Azusa Takahashi et al.   BIOMATERIALS

Elucidating the signaling mechanism of an epithelial tight-junction opening induced by chitosan

(2012) Li-Wen Hsu et al.   BIOMATERIALS

Sodium caprate as an enhancer of macromolecule permeation across tricellular tight junctions of intestinal cells

(2012) Susanne M. Krug et al.   BIOMATERIALS

Claudin-4-targeted optical imaging detects pancreatic cancer and its precursor lesions

(2012) Albrecht Neesse et al.   GUT

The application of an alanine-substituted mutant of the C-terminal fragment of Clostridium perfringens enterotoxin as a mucosal vaccine in mice

(2011) Hidehiko Suzuki et al.   BIOMATERIALS

Eradication of chemotherapy-resistant CD44+ human ovarian cancer stem cells in mice by intraperitoneal administration of clostridium perfringens enterotoxin

(2011) Francesca Casagrande et al.   CANCER

Elucidating the principles of the molecular organization of heteropolymeric tight junction strands

(2011) Jörg Piontek et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Claudin as a Target for Drug Development

(2011) A. Takahashi et al.   CURRENT MEDICINAL CHEMISTRY

Novel Clostridium perfringens enterotoxin suicide gene therapy for selective treatment of claudin-3- and -4-overexpressing tumors

(2011) W Walther et al.   GENE THERAPY

Mechanism ofClostridium perfringensEnterotoxin Interaction with Claudin-3/-4 Protein Suggests Structural Modifications of the Toxin to Target Specific Claudins

(2011) Anna Veshnyakova et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Crystal Structure ofClostridium perfringensEnterotoxin Displays Features of β-Pore-forming Toxins

(2011) Kengo Kitadokoro et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Structure of the Food-Poisoning Clostridium perfringens Enterotoxin Reveals Similarity to the Aerolysin-Like Pore-Forming Toxins

(2011) David C. Briggs et al.   JOURNAL OF MOLECULAR BIOLOGY

Glucocorticoid Insensitivity at the Hypoxic Blood–Brain Barrier Can Be Reversed by Inhibition of the Proteasome

(2011) Christoph Kleinschnitz et al.   STROKE

Mucosal vaccination using claudin-4-targeting

(2010) Hideki Kakutani et al.   BIOMATERIALS

Glucocorticoid effects on endothelial barrier function in the murine brain endothelial cell line cEND incubated with sera from patients with multiple sclerosis

(2010) Kinga G Blecharz et al.   Multiple Sclerosis Journal

On the Interaction of Clostridium perfringens Enterotoxin with Claudins

(2010) Anna Veshnyakova et al.   Toxins

Structure and Function of Extracellular Claudin Domains

(2009) Gerd Krause et al.   Annals of the New York Academy of Sciences

Molecular Determinants of the Interaction betweenClostridium perfringensEnterotoxin Fragments and Claudin-3

(2009) Lars Winkler et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Clostridium perfringensEnterotoxin Interacts with Claudins via Electrostatic Attraction

(2009) Jun Kimura et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A Novel Tumor-Targeted Therapy Using a Claudin-4-Targeting Molecule

(2009) R. Saeki et al.   MOLECULAR PHARMACOLOGY

Structure and function of claudins

(2007) Gerd Krause et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Formation of tight junction: determinants of homophilic interaction between classic claudins

(2007) Jörg Piontek et al.   FASEB JOURNAL