Human Claudin-8 and -14 Are Receptors Capable of Conveying the Cytotoxic Effects of Clostridium perfringens Enterotoxin

Proof of concept for claudin-targeted drug development

(2012) Hidehiko Suzuki et al.   Annals of the New York Academy of Sciences

Analysis of absorption enhancers in epithelial cell models

(2012) Rita Rosenthal et al.   Annals of the New York Academy of Sciences

Claudin-4 as therapeutic target in cancer

(2012) A. Neesse et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

Comparison of mucosal absorption-enhancing activity between a claudin-3/-4 binder and a broadly specific claudin binder

(2012) Koji Matsuhisa et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Targeting claudin-4 in human pancreatic cancer

(2012) Takashi Kojima et al.   EXPERT OPINION ON THERAPEUTIC TARGETS

Cysteine-Scanning Mutagenesis Supports the Importance of Clostridium perfringens Enterotoxin Amino Acids 80 to 106 for Membrane Insertion and Pore Formation

(2012) Jianwu Chen et al.   INFECTION AND IMMUNITY

Mechanism ofClostridium perfringensEnterotoxin Interaction with Claudin-3/-4 Protein Suggests Structural Modifications of the Toxin to Target Specific Claudins

(2011) Anna Veshnyakova et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Crystal Structure ofClostridium perfringensEnterotoxin Displays Features of β-Pore-forming Toxins

(2011) Kengo Kitadokoro et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Structure of the Food-Poisoning Clostridium perfringens Enterotoxin Reveals Similarity to the Aerolysin-Like Pore-Forming Toxins

(2011) David C. Briggs et al.   JOURNAL OF MOLECULAR BIOLOGY

On the Interaction of Clostridium perfringens Enterotoxin with Claudins

(2010) Anna Veshnyakova et al.   Toxins

Specificity of Interaction between Clostridium perfringens Enterotoxin and Claudin-Family Tight Junction Proteins

(2010) Leslie Mitchell et al.   Toxins

Identification of a Claudin-4 Residue Important for Mediating the Host Cell Binding and Action of Clostridium perfringens Enterotoxin

(2009) S. L. Robertson et al.   INFECTION AND IMMUNITY

Molecular Determinants of the Interaction betweenClostridium perfringensEnterotoxin Fragments and Claudin-3

(2009) Lars Winkler et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Clostridium perfringensEnterotoxin Interacts with Claudins via Electrostatic Attraction

(2009) Jun Kimura et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Physiology and Function of the Tight Junction

(2009) J. M. Anderson et al.   Cold Spring Harbor Perspectives in Biology

Domain mapping of a claudin-4 modulator, the C-terminal region of C-terminal fragment of Clostridium perfringens enterotoxin, by site-directed mutagenesis

(2008) Azusa Takahashi et al.   BIOCHEMICAL PHARMACOLOGY

Potential use of tight junction modulators to reversibly open membranous barriers and improve drug delivery

(2008) Mária A. Deli   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Noncytotoxic Clostridium perfringens Enterotoxin (CPE) Variants Localize CPE Intestinal Binding and Demonstrate a Relationship between CPE-Induced Cytotoxicity and Enterotoxicity

(2008) J. G. Smedley et al.   INFECTION AND IMMUNITY

Structural Constraints for the Binding of Short Peptides to Claudin-4 Revealed by Surface Plasmon Resonance

(2008) Jun Ling et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Structure and function of claudins

(2007) Gerd Krause et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Formation of tight junction: determinants of homophilic interaction between classic claudins

(2007) Jörg Piontek et al.   FASEB JOURNAL