The exposure of autoantigens by microparticles underlies the formation of potent inflammatory components: the microparticle-associated immune complexes

Increased IgG on cell-derived plasma microparticles in systemic lupus erythematosus is associated with autoantibodies and complement activation

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Platelets can enhance vascular permeability

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Autoantibody Epitope Spreading in the Pre-Clinical Phase Predicts Progression to Rheumatoid Arthritis

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Microparticles as antigenic targets of antibodies to DNA and nucleosomes in systemic lupus erythematosus

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Platelets Participate in Synovitis via Cox-1–Dependent Synthesis of Prostacyclin Independently of Microparticle Generation

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Lipopolysaccharide Signaling without a Nucleus: Kinase Cascades Stimulate Platelet Shedding of Proinflammatory IL-1 -Rich Microparticles

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Impact of pre-analytical parameters on the measurement of circulating microparticles: towards standardization of protocol

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Detection and isolation of cell-derived microparticles are compromised by protein complexes resulting from shared biophysical parameters

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Microparticles stimulate angiogenesis by inducing ELR+ CXC-chemokines in synovial fibroblasts

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Human platelet FcγRIIA and phagocytes in immune-complex clearance

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Microparticles and their roles in inflammatory arthritides

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Pathogenetic mechanisms in the initiation and perpetuation of Sjögren's syndrome

(2010) Michael Voulgarelis et al.   Nature Reviews Rheumatology

The role of defective clearance of apoptotic cells in systemic autoimmunity

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Platelets Amplify Inflammation in Arthritis via Collagen-Dependent Microparticle Production

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The majority of circulating platelet-derived microparticles fail to bind annexin V, lack phospholipid-dependent procoagulant activity and demonstrate greater expression of glycoprotein Ib

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Circulating microparticles remain associated with complement activation despite intensive anti-inflammatory therapy in early rheumatoid arthritis

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Autoimmunity against Fibrinogen Mediates Inflammatory Arthritis in Mice

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The role of microparticles in the pathogenesis of rheumatic diseases

(2009) Christian Beyer et al.   Nature Reviews Rheumatology

A broad screen for targets of immune complexes decorating arthritic joints highlights deposition of nucleosomes in rheumatoid arthritis

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Microparticle-induced release of B-lymphocyte regulators by rheumatoid synoviocytes

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Increased levels of circulating microparticles in primary Sjögren's syndrome, systemic lupus erythematosus and rheumatoid arthritis and relation with disease activity

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Evidence of platelet activation in multiple sclerosis

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Circulating immune complexes contain citrullinated fibrinogen in rheumatoid arthritis

(2008) Xiaoyan Zhao et al.   ARTHRITIS RESEARCH & THERAPY