Toll-Like Receptors Expressed by Synovial Fibroblasts Perpetuate Th1 and Th17 Cell Responses in Rheumatoid Arthritis

Hypoxia-Inducible Factor-1α and Interleukin 33 Form a Regulatory Circuit to Perpetuate the Inflammation in Rheumatoid Arthritis

(2013) Fanlei Hu et al.   PLoS One

Triggering of the dsRNA Sensors TLR3, MDA5, and RIG-I Induces CD55 Expression in Synovial Fibroblasts

(2012) Olga N. Karpus et al.   PLoS One

Spontaneous Production of Immunoglobulin M in Human Epithelial Cancer Cells

(2012) Fanlei Hu et al.   PLoS One

RNA sensors in human osteoarthritis and rheumatoid arthritis synovial fibroblasts: Immune regulation by vasoactive intestinal peptide

(2011) Mar Carrión et al.   ARTHRITIS AND RHEUMATISM

Blockade of Toll-like receptor 2 prevents spontaneous cytokine release from rheumatoid arthritis ex vivo synovial explant cultures

(2011) Sinéad Nic An Ultaigh et al.   ARTHRITIS RESEARCH & THERAPY

Synovial tissue hypoxia and inflammation in vivo

(2010) C. T. Ng et al.   ANNALS OF THE RHEUMATIC DISEASES

LY2439821, a humanized anti-interleukin-17 monoclonal antibody, in the treatment of patients with rheumatoid arthritis: A phase I randomized, double-blind, placebo-controlled, proof-of-concept study

(2010) M. C. Genovese et al.   ARTHRITIS AND RHEUMATISM

Pharmacology of TNF blockade in rheumatoid arthritis and other chronic inflammatory diseases

(2010) Peter C Taylor   CURRENT OPINION IN PHARMACOLOGY

Toll-like receptor 3 upregulation in macrophages participates in the initiation and maintenance of pristane-induced arthritis in rats

(2010) Liesu Meng et al.   ARTHRITIS RESEARCH & THERAPY

Fibroblast-like synoviocytes: key effector cells in rheumatoid arthritis

(2009) Beatrix Bartok et al.   IMMUNOLOGICAL REVIEWS

Targeted depletion of lymphotoxin-α–expressing TH1 and TH17 cells inhibits autoimmune disease

(2009) Eugene Y Chiang et al.   NATURE MEDICINE

Interleukin-17 and Type 17 Helper T Cells

(2009) Pierre Miossec et al.   NEW ENGLAND JOURNAL OF MEDICINE

Epidemiological studies in incidence, prevalence, mortality, and comorbidity of the rheumatic diseases

(2009) Sherine E Gabriel et al.   ARTHRITIS RESEARCH & THERAPY

Overexpression of toll-like receptors 3 and 4 in synovial tissue from patients with early rheumatoid arthritis: Toll-like receptor expression in early and longstanding arthritis

(2008) Caroline Ospelt et al.   ARTHRITIS AND RHEUMATISM

Evidence that cytokines play a role in rheumatoid arthritis

(2008) Fionula M. Brennan et al.   JOURNAL OF CLINICAL INVESTIGATION

Role of hypoxia-inducible factor-1  in hypoxia-induced expressions of IL-8, MMP-1 and MMP-3 in rheumatoid fibroblast-like synoviocytes

(2008) J. K. Ahn et al.   RHEUMATOLOGY